Dr Shahid Kazi - Researcher Profile

Biography

Shahid works in the Centre for Green Chemistry at Monash University as a Research Fellow.

Shahid's research areas of interest are:

• Natural product synthesis
• Organic synthesis
• Ligand synthesis
• Catalyst & Catalysis in organic synthesis
• Medicinal chemistry

Keywords

Anticancer agent, (+) discodermolide, Asymmetric synthesis, Green chemistry, IgG, quinoline thio-ether, Nucleic acid, TFO, aldol reaction, enantiopure, monoclonal antibody, hybridoma, radical reduction, small molecule enhancer, stereotriad, oxazaborolidinone

Qualifications

DOCTOR OF PHILOSOPHY / SYNTHETIC ORGANIC CHEMISTRY

Institution: Ehime University - Japan

Year awarded: 2003

MASTER'S BY RESEARCH-SYNTHETIC ORGANIC CHEMISTRY

Institution: Kochi University - Japan

Year awarded: 2001

MASTER'S BY RESEARCH-ORGANIC CHEMISTRY

Institution: University of Dhaka

Year awarded: 1996

BACHELOR OF SCIENCE WITH HONOURS - CHEMISTRY

Institution: University of Dhaka

Year awarded: 1994

Publications

Journal Articles

Kazi, S., Kelso, G., Harris, S., Boysen, R., Chowdhury, J., Hearn, M., 2010, Synthesis of quinoline thioethers as novel small molecule enhancers of monoclonal antibody production in mammalian cell culture, Tetrahedron [P], vol 66, issue 48, Pergamon Elsevier Science Ltd, Oxford England, pp. 9461-9467.

Kazi, S., Majumdar, A., Alam, R., Liu, S., Kuan, J.Y., Sui, X., Cuenoud, B., Glazer, P.M., Miller, P.S., Seidman, M.M., 2006, Targeted cross-linking of the human beta-globin gene in living cells mediated by a triple helix forming oligonucleotide, Biochemistry [P], vol 45, issue 6, American Chemical Society, United States, pp. 1970-1978.

Kiyooka, S., Kazi, S., Goto, F., Okazaki, M., Shuto, Y., 2003, Regulated-stereoselective construction of thirteen stereogenic centers necessary for the frame of (+)-Discodermolide, based on iterative Lewis Acid-promoted Aldol reactions, Journal Of Organic Chemistry [P], vol 68, issue 21, American Chemical Society, United States, pp. 7967-7978.

Kazi, S.A., Li, Y.N., Okazaki, M., Shuto, Y., Goto, F., Kiyooka, S., 2002, A short synthesis of the C15-C21 segment of (+)-discodermolide, based on an asymmetric approach from achiral 2-methyl-1,3-propanediol to versatile enantiopure stereotriads, Tetrahedron Letters [P], vol 43, issue 36, Pergamon, United Kingdom, pp. 6373-6376.

Kazi, S.A., Mursheda, J., Okazaki, M., Shuto, Y., Goto, F., Kiyooka, S., 2002, A straightforward, highly stereoselective construction of eight stereogenic centers in (+)-discodermolide C1-C13 segment, based on a strategy of iterative aldol reactions, Tetrahedron Letters [P], vol 43, issue 36, Pergamon, United Kingdom, pp. 6377-6381.

Kiyooka, S., Kazi, S.A., 2001, A divergent synthesis of essentially enantiopure syn- and anti-propionate aldol adducts based on the chiral 1,3,2-oxazaborolidin-5-one-promoted asymmetric aldol reaction followed by diastereoselective radical reduction, Bulletin Of The Chemical Society Of Japan [P], vol 74, issue 8, Chemical Society of Japan, Japan, pp. 1485-1495.

Kiyooka, S., Kazi, S.A., 2000, An efficient method for the synthesis of enantiopure 2,3-anti-propionate aldols involving a 3,5-syn- or anti-diol subunit through chiral borane-mediated enantioselective aldol reaction coupled with radical reduction, Tetrahedron Letters [P], vol 41, issue 15, Pergamon, United Kingdom, pp. 2633-2637.