Dr Glen Carter - Researcher Profile

Biography

Glen works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

PHD

Institution: University of Nottingham

Year awarded: 2005

Publications

Book Chapters

Carter, G.P., Lyras, D., Poon, R., Howarth, P., Rood, J.I., 2010, Methods for gene cloning and targeted mutagenesis, in Methods in Molecular Biology - Clostridium difficile: Methods and Protocols, eds Peter Mullany and Adam P Roberts, Humana Press, UK, pp. 183-201.

Davis, I.J., Carter, G.P., Young, M., Minton, N.P., 2005, Gene cloning in clostridia, in Handbook on Clostridia, eds Peter Durre, CRC Press, Boca Raton USA, pp. 37-52.

Journal Articles

Carter, G.P., Rood, J.I., Lyras, D., 2012, The role of toxin A and toxin B in the virulence of clostridium difficile, Trends in Microbiology [P], vol 20, issue 1, Elsevier Ltd * Trends Journals, UK, pp. 21-29.

Walk, S., Jain, R., Trivedi, I., Grossman, S., Newton, D., Thelen, T., Hao, Y., Songer, J., Carter, G., Lyras, D., Young, V., Aronoff, D., 2011, Non-toxigenic Clostridium sordellii: Clinical and microbiological features of a case of cholangitis-associated bacteremia, Anaerobe [P], vol 17, issue 5, Elsevier Science Ltd, UK, pp. 252-256.

Carter, G.P., Awad, M.M., Kelly, M.L., Rood, J.I., Lyras, D., 2011, TcdB or not TcdB: a tale of two Clostridium difficile toxins, Future Microbiology [P], vol 6, issue 2, Future Medicine Ltd, UK, pp. 121-123.

Carter, G.P., Awad, M.M., Hao, Y., Thelen, T., Bergin, I.L., Howarth, P.M., Seemann, T., Rood, J.I., Aronoff, D.M., Lyras, D., 2011, TcsL Is an Essential Virulence Factor in Clostridium sordellii ATCC 9714, Infection And Immunity [P], vol 79, issue 3, American Society for Microbiology, USA, pp. 1025-1032.

Carter, G.P., Douce, G.R., Govind, R., Howarth, P.M., Mackin, K.E., Spencer, J., Buckley, A.M., Antunes, A., Kotsanas, D., Jenkin, G.A., Dupuy, B., Rood, J.I., Lyras, D., 2011, The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile, Plos Pathogens [P], vol 7, issue 10 (Art. No: e1002317), Public Library of Science, USA, pp. 1-11.

Chakravorty, A., Awad, M., Hiscox, T., Cheung, K., Carter, G., Choo, J., Lyras, D., Rood, J., 2011, The cysteine protease alpha-clostripain is not essential for the pathogenesis of Clostridium perfringens-mediated myonecrosis, PLoS ONE [P], vol 6, issue 7 (Art. No: e22762), Public Library of Science, USA, pp. 1-7.

Cheung, J.K., Keyburn, A.L., Carter, G.P., Lanckriet, A.L., Van Immerseel, F., Moore, R.J., Rood, J.I., 2010, The VirSR two-component signal transduction system regulates NetB toxin production in Clostridium perfringens, Infection And Immunity [P], vol 78, issue 7, American Society for Microbiology, USA, pp. 3064-3072.

Carter, G.P., Rood, J.I., Lyras, D., 2010, The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives, Gut Microbes [P], vol 1, issue 1, Landes Bioscience, USA, pp. 58-64.

Lyras, D., O'Connor, J.R., Howarth, P.M., Sambol, S.P., Carter, G.P., Phumoonna, T., Poon, R., Adams, V.M., Vedantam, G., Johnson, S., Gerding, D., Rood, J.I., 2009, Toxin B is essential for virulence of Clostridium difficile, Nature, vol 458, issue 7242, Nature Publishing Group, UK, pp. 1176-1179.

Carter, G.P., Lyras, D., Allen, D.L., Mackin, K., Howarth, P., O'Connor, J.R., Rood, J.I., 2007, Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator, Journal of Bacteriology, vol 189, issue 10, American Society of Microbiology, Washington, DC, USA, pp. 7290-7301.

Heap, J.T., Pennington, O., Cartman, S.T., Carter, G.P., Minton, N., 2007, The ClosTron: a universal gene knock-out system for the genus Clostridium, Journal of Microbiological Methods, vol 70, issue 3, Elsevier Science BV, Amsterdam, The Netherlands, pp. 452-464.

Carter, G.P., Purdy, D., Williams, P., Minton, N.P., 2005, Quorum sensing in Clostridium difficile: analysis of a luxS-type signalling system, Journal of Medical Microbilogy, vol 54, issue Pt 2, Society General Microbiology, Spencers Woods England, pp. 119-127.

Minton, N., Carter, G.P., Herbert, M., O'Keeffe, T., Purdy, D., Elmore, M., Ostrowski, A., Pennington, O., Davis, I., 2004, The development of Clostridium difficile genetic systems, Anaerobe, vol 10, issue 2, Elsevier Sci Ltd, Oxford England, pp. 75-84.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Analysis of Clostridium difficile Colonisation Factors.

Supervisors:

Carter, G (Joint), Lyras, D (Joint-co).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The use of recombinant B. subtilis spores as C. difficile vaccines.

Supervisors:

Lyras, D (Main), Carter, G (Associate), Johanesen, P (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Understanding the role of the gut mucus layer in susceptibility to Clostridium difficile infection.

Supervisors:

Carter, G (Joint), Lyras, D (Joint-co).