Dr Maria Liaskos - Researcher Profile

Biography

Maria works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Keywords

bacterial pathogenesis, Helicobacter pylori, innate and adaptive immunity

Qualifications

DOCTOR OF PHILOSOPHY

Institution: The University of Melbourne

Year awarded: 2005

Publications

Book Chapters

Kaparakis, M., Allison, C., Hutton, M., Ferrero, R., 2010, Innate immune initiators and effectors in Helicobacter pylori infection, in Helicobacter pylori in the 21st Century, eds Philip Sutton and Hazel M. Mitchell, CABI, UK, pp. 142-166.

Journal Articles

Gantier, M.P.M., Stunden, H.J., McCoy, C., Behlke, M.A., Wang, D., Liaskos, M., Sarvestani, S., Yang, Y.H., Xu, D., Corr, S.C., Morand, E.F., Williams, B.R.G., 2012, A miR-19 regulon that controls NF-{kappa}B signaling, Nucleic Acids Research [P], vol 40, issue 16, Oxford University Press, United Kingdom, pp. 8048-8058.

Hutton, M., Liaskos, M., Ferrero, R., 2012, The use of AlbuMAX II[R] as a blood or serum alternative for the culture of helicobacter pylori, Helicobacter [E], vol 17, issue 1, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 68-76.

Liaskos, M., Turnbull, L., Carneiro, L., Firth, S.D., Coleman, H.A., Parkington, H.C., Le Bourhis, L., Karrar, A., Viala, J., Mak J., Hutton, M.L., Davies, J.K., Crack, P.J., Hertzog, P.J., Philpott, D., Girardin, S.E., Whitchurch, C.B., Ferrero, R.L., 2010, Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells, Cellular Microbiology [P], vol 12, Wiley-Blackwell Publishing Ltd, UK, pp. 372-385.

Gantier, M.P.M., Irving, A.T., Liaskos, M., Xu, D., Evans, V., Cameron, P.U., Bourne, J.A., Ferrero, R.L., John, M., Behlke, M.A., Williams, B.R.G., 2010, Genetic modulation of TLR8 response following bacterial phagocytosis, Human Mutation [P], vol 31, issue 9, John Wiley & Sons, Inc., USA, pp. 1069-1079.

Hutton, M., Liaskos, M., Turner, L., Cardona, A., Kwok-Schuelein, T., Ferrero, R., 2010, Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells, Infection And Immunity [P], vol 78, issue 11, American Society for Microbiology, United States, pp. 4523-4531.

Ding, S., Fischer, W., Kaparakis-Liaskos, M., Liechti, G., Merrell, D., Grant, P.A., Ferrero, R., Crowe, S., Hass, R., Hatakeyama, M., Goldberg, J., 2010, Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis, PLoS ONE [P], vol 5, issue 4 (e9875), Public Library of Science, United States, pp. 1-15.

Grubman, A., Liaskos, M.(., Viala, J., Allison, C.C., Badea, L., Karrar, A., Boneca, I.G., Le Bourhis, L., Reeve, S.B., Smith, A.I., Hartland, E.L., Philpott, D.J., Ferrero, R.L., 2010, The innate immune molecule, NOD1, regulates direct killing of Helicobacter pylori by antimicrobial peptides, Cellular Microbiology [P], vol 12, Wiley-Blackwell Publishing Ltd, UK, pp. 626-639.

Grubman, A., Phillips, A., Thibonnier, M., Kaparakis-Liaskos, M., Johnson, C., Thiberge, J.-., Radcliffe, F.J., Ecobichon, C., Labigne, A., de Reuse, H., Mendz, G.L., Ferrero, R.L., 2010, Vitamin B 6 is required for full motility and virulence in Helicobacter pylori, mBio [E], vol 1, issue 3 (e00112-10), American Society for Microbiology, United States, pp. 1-9.

Chaouche-Drider, N., Kaparakis, M., Karrar, A., Fernandez, M., Carneiro, L.A.M., Viala, J., Boneca, I.G., Moran, A.P., Philpott, D.J., Ferrero, R.L., 2009, A commensal Helicobacter sp. of the rodent intestinal flora activates TLR2 and NOD1 responses in epithelial cells, PLoS ONE [P], vol 4, issue 4 (e5396), Public Library of Science, USA, pp. 1-10.

Allison, C.C., Kufer, T.A., Kremmer, E., Liaskos, M.(., Ferrero, R.L., 2009, Helicobacter pylori induces MAPK phosphorylation and AP-1 activation via a NOD1-dependent mechanism, Journal Of Immunology [P], vol 183, issue 12, American Association of Immunologists, USA, pp. 8099-8109.

Badea, L., Beatson, S.A., Kaparakis, M., Ferrero, R.L., Hartland, E.L., 2009, Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli, BMC Microbiology, vol 9, issue 30, BioMed Central Ltd, UK, pp. 1-10.

Kaparakis, M., Walduck, A.K., Price, J.D., Pedersen, J., van Rooijen, N., Pearse, M.J., Wijburg, O.L., Strugnell, R.A., 2008, Macrophages are mediators of gastritis in acute helicobacter pylori infection in C57BL/6 Mice, Infection and Immunity, vol 76, issue 5, American Society for Microbiology, USA, pp. 2235-2239.

Tan, M.P., Kaparakis, M., Galic, M., Pedersen, J.S., Pearse, M.J., Wijburg, O.L.C., Janssen, P.H., Strugnell, R.A., 2007, Chronic Helicobacter pylori infection does not significantly alter the microbiota of the murine stomach, Applied and Environmental Microbiology, vol 73, issue 3, American Society for Microbiology, USA, pp. 1010-1013.

Kaparakis, M., Philpott, D., Ferrero, R.L., 2007, Mammalian NLR proteins; discriminating foe from friend, Immunology & Cell Biology, vol 85, issue 6, Nature Publishing Group, New York NY USA, pp. 495-502.

McGuckin, M., Every, A.L., Skene, C.D., Linden, S.K., Chionh, Y.T., Swierczak, A., McAuley, J., Harbour, S., Kaparakis, M., Ferrero, R.L., Sutton, P., 2007, Muc1 mucin limits both Helicobacter pylori colonization of the murine gastric mucosa and associated gastritis, Gastroenterology, vol 133, issue 4, WB Saunders Co-Elsevier Inc, Philadelphia, PA, USA, pp. 1210-1218.

Kaparakis, M., Laurie, K.L., Wijburg, O.L.C., Pedersen, J.S., Pearse, M.J., van Driel, I.R., Gleeson, P.A., Strugnell, R.A., 2006, CD4+ CD25+ regulatory T cells modulate the T-cell and antibody responses in Helicobacter-infected BALB/c mice, Infection and Immunity, vol 74, issue 6, American Society for Microbiology, USA, pp. 3519-3529.

Activities

Education

From: 01/02/2010
Monash Institute of Medical Research
Postgraduate Committee Member

From: 01/03/2010
Monash Institute of Medical Research
National Scientists in Schools Program

From: 05/04/2010
Monash Institute of Medical Research
Victorian Undergraduate Research Opportunities (UROP)- Committee Member

Grants

Title:

Designing effective Gram negative bacterial vaccines.

Investigators:

Liaskos, M

Funding:

(2011 - 2015). Australian Research Council (ARC).

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The immunomodulatory roles of Helicobacter pylori outer membrane vesicles..

Supervisors:

Ferrero, R (Main), Kaparakis Liaskos, M (Associate).

Completed Supervision

Student:

Allison, C.

Program of Study:

The role of the pathogen recognition molecule, NOD1, in the induction of gastric epithelial cell signalling during Helicobacter pylori infection. (PHD) 2010.

Supervisors:

Davies, J (Main), Ferrero, R (Associate), Kaparakis Liaskos, M (Associate).

Student:

Hutton, M.

Program of Study:

The role of cholesterol in Helicobacter pylori interactions with host cells. (PHD) 2012.

Supervisors:

Ferrero, R (Main), Kaparakis Liaskos, M (Associate).