Dr Paul Cameron - Researcher Profile

Biography

Paul works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Senior Lecturer.

Qualifications

PHD

Institution: University of Western Australia

Year awarded: 1992

MEDICINE, SURGURY

Institution: University of Western Australia

Year awarded: 1979

MEDICAL SCIENCE

Institution: University of Western Australia

Year awarded: 1976

Publications

Journal Articles

Evans, V.A., Khoury, G., Saleh, S.M., Cameron, P.U., Lewin, S.R., 2012, HIV persistence: chemokines and their signalling pathways, Cytokine and Growth Factor Reviews [P], vol 23, issue 4-5, Elsevier Ltd, United Kingdom, pp. 151-157.

Rajasuriar, R., Booth, D.R., Gouillou, M., Spelman, T., James, I.R., Solomon, A., Chua, K., Stewart, G., Deeks, S.G., Bangsberg, D.R., Muzoora, C., Cameron, P., Hunt, P., Martin, J., Lewin, S., 2012, The role of SNPs in the a-chain of the IL-7R gene in CD4þ T-cell recovery in HIV-infected African patients receiving suppressive cART, Genes And Immunity [P], vol 13, Nature Publishing Group, United Kingdom, pp. 83-93.

Rajasuriar, R., Gouillou, M., Spelman, T., Read, T., Hoy, J., Law, M., Cameron, P., Petoumenos, K., Lewin, S.R., 2011, Clinical predictors of immune reconstitution following combination antiretroviral therapy in patients from the Australian HIV Observational Database., PLoS ONE [P], vol 6, issue 6, Public Library of Science, USA, pp. 1-10.

Tippett, E., Cheng, W., Westhorpe, C., Cameron, P., Brew, B., Lewin, S., Jaworowski, A., Crowe, S., 2011, Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals, PLoS ONE [P], vol 6, issue 5 (Art. No: e19968), Public Library of Science, United States, pp. 1-11.

Jones, K.L., Smyth, R.P., Pereira, C.d.F., Cameron, P.U., Lewin, S.R., Jaworowski, A., Mak, J., 2011, Early events of HIV-1 infection: Can signaling be the next therapeutic target?, Journal Of Neuroimmune Pharmacology [P], vol 6, issue 2, Springer New York LLC, USA, pp. 269-283.

Saleh, S., Wightman, F., Ramanayake, S., Alexander, M., Kumar, N., Khoury, G., Pereira, C., Purcell, D., Cameron, P., Lewin, S., 2011, Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells, Retrovirology [P], vol 8, issue 80, BioMed Central Ltd, UK, pp. 1-11.

Cameron, P., Jones, P., Gorniak, M., Dunster, K., Paul, E., Lewin, S., Woolley, I., Spelman, D., 2011, Splenectomy associated changes in IgM memory B cells in an adult spleen registry cohort, PLoS ONE [P], vol 6, issue 8 (Art. No: e23164), Public Library of Science, United States, pp. 1-8.

Khoury, G., Rajasuriar, R., Lewin, S., Cameron, P., 2011, The role of naive T-cells in HIV-1 pathogenesis: An emerging key player., Clinical Immunology [P], vol 141, issue 3, Academic Press (Elsevier), US, pp. 253-267.

Evans, V., Lal, L., Akkina, R., Solomon, A., Wright, E., Lewin, S., Cameron, P., 2011, Thymic plasmacytoid dendritic cells are susceptible to productive HIV-1 infection and efficiently transfer R5 HIV-1 to thymocytes in vitro, Retrovirology [P], vol 8, issue 43, BioMed Central Ltd, UK, pp. 1-12.

Cornall, A., Sharma, L., Solomon, A., Gorry, P., Crowe, S., Cameron, P.U., Lewin, S.R., 2010, A novel, rapid method to detect infectious HIV-1 from plasma of persons infected with HIV-1, Journal of Virological Methods [P], vol 165, issue 1, Elsevier BV, The Netherlands, pp. 90-96.

Rajasuriar, R., Booth, D., Solomon, A., Chua, K., Spelman, T., Gouillou, M., Schlub, T., Davenport, M., Crowe, S., Elliott, J., Hoy, J., Fairley, C., Stewart, G., Cameron, P., Lewin, S., 2010, Biological determinants of immune reconstitution in HIV-infected patients receiving antiretroviral therapy: The role of interleukin 7 and interleukin 7 receptor alpha and microbial translocation, Journal Of Infectious Diseases [P], vol 202, issue 8, Oxford University Press, USA, pp. 1254-1264.

Wightman, F., Solomon, A., Khoury, G., Green, J., Gray, L., Gorry, P.R., Ho, Y., Saksena, N., Hoy, J.F., Crowe, S., Cameron, P., Lewin, S., 2010, Both CD31+and CD31- naive CD4+ T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy, Journal of Infectious Diseases [E], vol 202, issue 11, Oxford University Press, United States, pp. 1738-1748.

Iser, D., Warner, N., Revill, P., Solomon, A., Wightman, F., Saleh, S., Crane, M., Cameron, P.U., Bowden, S., Nguyen, T., Pereira, C., Desmond, P., Locarnini, S., Lewin, S., 2010, Coinfection of hepatic cell lines with human immunodeficiency virus and hepatitis B virus leads to an increase in intracellular hepatitis B surface antigen, Journal Of Virology [P], vol 84, issue 12, American Society for Microbiology, USA, pp. 5860-5867.

Cameron, P., Saleh, S., Sallmann, G., Solomon, A., Wightman, F., Evans, V., Boucher, G., Haddad, E., Sekaly, R., Harman, A., Anderson, J., Jones, K.L., Mak, J., Cunningham, A., Jaworowski, A., Lewin, S., 2010, Establishment of HIV-1 latency in resting CD4 + T cells depends on chemokine-induced changes in the actin cytoskeleton, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 107, issue 39, National Academy of Sciences, USA, pp. 16934-16939.

Gantier, M.P.M., Irving, A.T., Liaskos, M., Xu, D., Evans, V., Cameron, P.U., Bourne, J.A., Ferrero, R.L., John, M., Behlke, M.A., Williams, B.R.G., 2010, Genetic modulation of TLR8 response following bacterial phagocytosis, Human Mutation [P], vol 31, issue 9, John Wiley & Sons, Inc., USA, pp. 1069-1079.

Lichtfuss, G., Meehan, A., Cheng, W., Cameron, P., Lewin, S., Crowe, S., Jaworowski, A., 2010, HIV inhibits early signal transduction events triggered by CD16 cross-linking on NK cells, which are important for antibody-dependent cellular cytotoxicity, Journal of Leukocyte Biology [P], vol 89, Federation of American Societies for Experimental Biology, USA, pp. 149-158.

Polizzotto, M., Jones, P., Cameron, P., Spelman, D., Woolley, I., 2010, The influence of splenectomy on the infectious complications and outcomes of people With HIV: Marked, sustained elevation in risk of severe infection with bacteria including Streptococcus pneumoniae, Jaids-Journal Of Acquired Immune Deficiency Syndromes [P], vol 55, issue 3, Lippincott Williams & Wilkins, USA, pp. e24-e26.

Abbott, I., Chang, C.C., Skinner, M.J., Street, A., Perry, G., McLean, C., Wright, E.J., Cameron, P.U., 2009, Development and management of systemic lupus erythematosus in an HIV-infected man with hepatitis C and B co-infection following interferon therapy: A case report, Journal of Medical Case Reports [E], vol 3, issue 7289, BioMed Central Ltd, United Kingdom, pp. 1-5.

Van der Meulen, J.D., Mifsud, N.A., Abud, D., Paul, E., Varney, M., Lewin, S.R., Cameron, P.U., Kotsimbos, T.C., 2009, Differential dynamics of donor DC and non-DC peripheral blood mononuclear cell microchimerism in lung transplantation, Clinical Immunology [P], vol 133, issue 2, Academic Press, United States, pp. 179-183.

Chang, J.J., Sirivichayakul, S., Avihingsanon, A., Thompson, A.J.V., Revill, P., Iser, D., Slavin, J., Buranapraditkun, S., Marks, P., Matthews, G., Cooper, D.A., Kent, S., Cameron, P.U., Sasadeusz, J., Desmond, P., Locarnini, S., Dore, G., Ruxrungtham, K., Lewin, S.R., 2009, Impaired quality of the hepatitis B virus (HBV)-specific T-cell response in human immunodeficiency virus type 1-HBV coinfection, Journal Of Virology [P], vol 83, issue 15, American Society for Microbiology, United States, pp. 7649-7658.

Shehu-Xhilaga, M., Rhodes, D., Wightman, F., Liu, H.B., Solomon, A., Saleh, S.M., Dear, A.E., Cameron, P.U., Lewin, S.R., 2009, The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells, AIDS [P], vol 23, issue 15, Lippincott Williams & Wilkins, United States, pp. 2047-2050.

Evans, V., Cameron, P.U., Lewin, S.R., 2008, Human thymic dendritic cells: regulators of T cell development in health and HIV-1 infection, Clinical Immunology [P], vol 126, issue 1, Academic Press, USA, pp. 1-12.

Lewin, S.R., Murray, J.M., Solomon, A., Wightman, F., Cameron, P.U., Purcell, D.J., Zaunders, J.J., Grey, P., Bloch, M., Smith, D., Cooper, D.A., Kelleher, A.D., 2008, Virologic determinants of success after structured treatment interruptions of antiretrovirals in acute HIV-1 infection, Jaids-Journal Of Acquired Immune Deficiency Syndromes [P], vol 47, issue 2, Lippincott Williams & Wilkins, USA, pp. 140-147.

Saleh, S.M., Solomon, A., Wightman, F., Shehu-Xhilaga, M., Cameron, P.U., Lewin, S.R., 2007, CCR7 ligands CCL19 and CCL21 increase permissiveness of resting memory CD4+ T cells to HIV-1 infection: a novel model of HIV-1 latency, Blood, vol 110, issue 13, American Society of Hematology, USA, pp. 4161-4164.

Cameron, P.U., Handley, A., Baylis, D.C., Solomon, A., Bernard, N., Purcell, D., Lewin, S.R., 2007, Preferential infection of dendritic cells during human immunodeficiency virus type 1 infection of blood leukocytes, Journal of Virology, vol 81, issue 5, American Society for Microbiology, US, pp. 2297-2306.

Ellery, P., Tippett, E.D., Chiu, Y., Paukovics, G., Cameron, P.U., Solomon, A., Lewin, S.R., Gorry, P.R., Jaworowski, A., Greene, W.C., Sonza, S., Crowe, S.M., 2007, The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo, The Journal of Immunology, vol 178, issue 10, American Association of Immunologists, USA, pp. 6581-6589.

Chang, J.J., Thompson, A.J.V., Visvanathan, K., Kent, S.J., Cameron, P.U., Wightman, F., Desmond, P.V., Locarnini, S., Lewin, S.R., 2007, The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection, Hepatology, vol 46, issue 5, John Wiley & Sons Inc, USA, pp. 1332-1340.

Shehu-Xhilaga, M., Kent, S.J., Batten, J., Ellis, S., Van der Meulen, J.D., O'Bryan, M.K., Cameron, P.U., Lewin, S.R., Hedger, M.P., 2007, The testis and epididymis are productively infected by SIV and SHIV in juvenile macaques during the post-acute stage of infection, Retrovirology, vol 4, issue 1, BioMed Central Ltd, United Kingdom, pp. 1-13.

Kedzierska, K., Paukovics, G., Handley, A., Hewish, M., Hocking, J., Cameron, P.U., Crowe, S.M., 2004, Interferon-gamma Therapy Activates Human Monocytes for Enhanced Phagocytosis of Mycobacterium avium Complex in HIV-Infected Individuals, HIV Clinical Trials, vol 5, issue 2, Thomas Land Publishers, Inc, USA, pp. 80-85.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Characterisation of human cytomegalovirus (CMV) specific T cell immunity following haematopoietic stem cell transplantation (HSCT): toward improved management of CMV end organ disease.

Supervisors:

Lewin, S (Main), Cameron, P (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

DC induced establishment of HIV-1 latency in resting memory CD4+ T cells..

Supervisors:

Cameron, P (Joint), Lewin, S (Joint-co), Evans, V (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Viral reservoirs- role of naive T-cells in the pathogenesis of T-Cell decline and long term persistence of HIV infection.

Supervisors:

Cameron, P (Joint), Lewin, S (Joint-co).

Completed Supervision

Student:

Evans, V.

Program of Study:

Dendritic cell and T cell interactions: their role in HIV-1 spread and latency. (PHD) 2010.

Supervisors:

Cameron, P (Joint), Lewin, S (Joint-Co).

Student:

Evans, V.

Program of Study:

HIV. 2005.

Supervisors:

Cameron, P (Joint-Co), Lewin, S (Joint).

Student:

Rajasuriar, R.

Program of Study:

Biological determinants of long-term immune reconstitution following combination antiretroviral therapy (cART). (PHD) 2011.

Supervisors:

Cameron, P (Joint), Lewin, S (Joint-Co).

Student:

Tippett, E.

Program of Study:

The role of monocyte subsets in HIV-1 pathogenesis and their contribution to the viral reservoir. (PHD) 2011.

Supervisors:

Crowe, S (Main), Cameron, P (Associate), Lewin, S (Associate).