Dr Saleela Ruwanpura - Researcher Profile

Biography

Saleela works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Keywords

lung cancer, emphysema, IL-6, Stat3, genetic models

Qualifications

MEDICINE

Institution: Monash University

Year awarded: 2008

BIOMEDICAL SCIENCE (HONS)

Institution: Monash University

Year awarded: 2003

Publications

Journal Articles

Ruwanpura, S., McLeod, L., Miller, A., Jones, J., Vlahos, R., Ramm, G., Longano, A., Bardin, P., Bozinovski, S., Anderson, G., Jenkins, B., 2012, Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice, American Journal Of Physiology-Lung Cellular And Molecular Physiology [P], vol 32, issue 7, American Physiological Society, Untied States, pp. L627-L639.

Ruwanpura, S., McLeod, L., Miller, A., Jones, J., Bozinovski, S., Vlahos, R., Ernst, M., Armes, J., Bardin, P., Anderson, G., Jenkins, B., 2011, Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice, American Journal Of Respiratory Cell And Molecular Biology [P], vol 45, issue 4, American Thoracic Society, United States, pp. 720-730.

Ruwanpura, S., McLachlan, R., Meachem, S., 2010, Hormonal regulation of male germ cell development, Journal of Endocrinology [P], vol 205, issue 2, BioScientifica Ltd., United Kingdom, pp. 117-131.

Crosbie, J., Anderson, R., Rothkamm, K., Restall, C., Cann, L.M., Ruwanpura, S.M., Meachem, S.J., Yagi, N., Svalbe, I.D., Lewis, R., Williams, B.R.G., Rogers, P.A.W., 2010, Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues, International Journal of Radiation Oncology Biology Physics [P], vol 77, issue 3, Elsevier Inc., USA, pp. 886-894.

Ruwanpura, S.M., McLachlan, R.I., Stanton, P.G., Meachem, S.J., 2008, Follicle-stimulating hormone affects spermatogonial survival by regulating the intrinsic apoptotic pathway in adult rats, Biology of Reproduction, vol 78, issue 4, Society for the Study of Reproduction, Madison WI USA, pp. 705-713.

Ruwanpura, S.M., McLachlan, R.I., Matthiesson, K.L., Meachem, S.J., 2008, Gonadotrophins regulate germ cell survival, not proliferation, in normal adult men, Human Reproduction, vol 23, issue 2, Oxford University Press, Oxford, UK, pp. 403-411.

Ruwanpura, S.M., McLachlan, R.I., Stanton, P.G., Loveland, K.A.L., Meachem, S.J., 2008, Pathways involved in testicular germ cell apoptosis in immature rats after FSH suppression, Journal of Endocrinology, vol 197, issue 1, Society of Endocrinology, Bristol, UK, pp. 35-43.

Meachem, S.J., Schlatt, S., Ruwanpura, S.M., Stanton, P.G., 2007, The effect of testosterone, dihydrotestosterone and oestradiol on the re-initiation of spermatogenesis in the adult photoinhibited Djungarian hamster, Journal of Endocrinology, vol 192, issue 3, Society of Endocrinology, Bristol England UK, pp. 553-561.

Meachem, S.J., Ruwanpura, S.M., Ziolkowski, J., Ague, J.M., Skinner, M.K., Loveland, K.A.L., 2005, Developmentally distinct in vivo effects of FSH on proliferation and apoptosis during testis maturation, Journal of Endocrinology, vol 186, issue 12, Society for Endocrinology, UK, pp. 429-446.

Awards

Academic awards (national, international)
2009 - 2010
Bridging Fellowship
Monash University Faculty of Medicine Nursing and Health Science

Academic prizes (national, international)
2011 - 2011
Cell Biology/Immunology Prize
TSANZ

Grants

Title:

Deregulated cytokine signalling as a molecular bridge between the pathogenesis of emphysema and lung cancer.

Investigators:

Ruwanpura, S

Funding:

(2010 - 2014). National Health & Medical Research Council (NHMRC).

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Deregulated IL-6 signalling as a key molecular bridge linking the pathogenesis of emphysema and L/C.

Supervisors:

Jenkins, B (Main), Ruwanpura, S (Associate), Watkins, D (Associate).