Dr Gregory Moseley - Researcher Profile

Biography

Gregory works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

PHD

Institution: Sheffield

Year awarded: 2002

HONS. BIOCHEMISTRY

Institution: University of York

Year awarded: 1996

Publications

Journal Articles

Oksayan, S., Wiltzer, L., Rowe, C.L., Blondel, D., Jans, D.A., Moseley, G.W., 2012, A novel nuclear trafficking module regulates the nucleocytoplasmic localization of the rabies virus interferon antagonist, P protein, Journal Of Biological Chemistry [P], vol 287, issue 33, American Society for Biochemistry and Molecular Biology Inc., USA, pp. 28112-28121.

Wiltzer, L., Larrous, F., Oksayan, S., Ito, N., Marsh, G.A., Blondel, D., Bourhy, H., Jans, D.A., Moseley, G.W., 2012, Conservation of a unique mechanism of immune evasion across the Lyssavirus genus, Journal Of Virology [P], vol 86, issue 18, American Society for Microbiology, USA, pp. 10194-10199.

Oksayan, S., Ito, N., Moseley, G.W., Blondel, D., 2012, Subcellular trafficking in rhabdovirus infection and immune evasion: a novel target for therapeutics, Infectious Disorders - Drug Targets [P], vol 12, issue 1, Bentham Science Publishers Ltd, The Netherlands, pp. 38-58.

Moseley, G., Jans, D., 2012, Subcellular trafficking of pathogens: targeting for therapeuticsUntitled Publication, Infectious Disorders - Drug Targets [P], vol 12, issue 1, Bentham Science Publishers Ltd, The Netherlands, pp. 2-3.

Moseley, G.W., 2012, Viral interferon antagonism: Making the leap from the bench to the clinic, Journal of Virology & Antiviral Research [P], vol 1, issue 1, SciTechnol, USA, pp. 1-2.

Martino Roth, D., Moseley, G., Pouton, C., Jans, D., 2011, Mechanism of microtubule-facilitated "fast track" nuclear import, Journal Of Biological Chemistry [P], vol 286, issue 16, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 14335-14351.

Moseley, G.W., Leyton, D.L., Glover, D.J., Filmer, R.P., Jans, D.A., 2010, Enhancement of protein transduction-mediated nuclear delivery by interaction with dynein/microtubules, Journal of Biotechnology [P], vol 145, Elsevier BV, The Netherlands, pp. 222-225.

Ito, N., Moseley, G.W., Blondel, D., Shimizu, K., Rowe, C.L., Ito, Y., Masatani, T., Nakagawa, K., Jans, D.A., Sugiyama, M., 2010, Role of interferon antagonist activity of rabies virus phosphoprotein in viral pathogenicity, Journal Of Virology [P], vol 84, issue 13, American Society for Microbiology, USA, pp. 6699-6710.

Glover, D., Leyton, D.L., Moseley, G.W., Jans, D.A., 2010, The efficiency of nuclear plasmid DNA delivery is a critical determinant of transgene expression at the single cell level, Journal Of Gene Medicine [P], vol 12, John Wiley & Sons, Inc., USA, pp. 77-85.

Parthasarathy, V., Martin, F., Higginbottom, A., Murray, H., Moseley, G.W., Read, R.C., Mal, G., Hulme, R., Monk, P.N., Partridge, L.J., 2009, Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells, Immunology [P], vol 127, issue 2, Wiley-Blackwell Publishing Ltd., UK, pp. 237-248.

Moseley, G.W., Lahaye, X., Roth, D.M., Oksayan, S., Filmer, R.P., Rowe, C.L., Blondel, D., Jans, D.A., 2009, Dual modes of rabies P-protein association with microtubules: a novel strategy to suppress the antiviral response, Journal Of Cell Science [P], vol 122, issue 20, The Company of Biologists Ltd, UK, pp. 3652-3662.

Hassuna, N., Monk, P.N., Moseley, G.W., Partridge, L.J., 2009, Strategies for targeting tetraspanin proteins: Potential therapeutic applications in microbial infections, BioDrugs [P], vol 23, issue 6, Adis International Ltd, NZ, pp. 341-359.

Roth, D., Moseley, G.W., Glover, D., Pouton, C.W., Jans, D.A., 2007, A microtubule-facilitated nuclear import pathway for cancer regulatory proteins, Traffic, vol 8, issue 6, Blackwell Publishing, Oxford England UK, pp. 673-686.

Moseley, G.W., Roth, D., De Jesus, M., Leyton, D.L., Filmer, R., Pouton, C.W., Jans, D.A., 2007, Dynein light chain association sequences can facilitate nuclear protein import, Molecular Biology of the Cell, vol 18, issue 8, The American Society for Cell Biology, Bethesda MD USA, pp. 3204-3213.

Moseley, G.W., Filmer, R., De Jesus, M., Jans, D.A., 2007, Nucleocytoplasmic distribution of rabies virus P-protein is regulated by phosphorylation adjacent to C-terminal nuclear import and export signals, Biochemistry, vol 46, issue 43, American Chemical Society, Washington DC USA, pp. 12053-12061.

Pouton, C.W., Wagstaff, K.M., Roth, D., Moseley, G.W., Jans, D.A., 2007, Targeted delivery to the nucleus, Advanced Drug Delivery Reviews, vol 59, issue 8, Elsevier Science BV, Amsterdam, pp. 698-717.

Ho, S., Martin, F., Higginbottom, A., Partridge, L.J., Parthasarathy, V., Moseley, G.W., Lopez, P., Cheng-Mayer, C., Monk, P.N., 2006, Recombinant extracellular domains of tetraspanin proteins are potent inhibitors of the infection of macrophages by human immunodeficiency virus type 1, Journal of Virology, vol 80, issue 13, American Society for Microbiology, Washington USA, pp. 6487-6496.

Moseley, G.W., 2005, Tetraspanin-Fc receptor interactions, Platelets, vol 16, issue 1, Taylor & Francis Ltd, Abingdon England, pp. 3-11.

Martin, F., Roth, D.M., Jans, D.A., Pouton, C.W., Partridge, L.J., Monk, P.N., Moseley, G.W., 2005, Tetraspanins in viral infections: a fundamental role in viral biology?, Journal of Virology, vol 79, issue 17, American Society for Microbiology, USA, pp. 10839-10851.

Wright, M.D., Geary, S., Fitter, S., Moseley, G.W., Lau, L., Sheng, K., Apostolopoulos, V., Stanley, E., Jackson, D., Ashman, L.K., 2004, Characterization of mice lacking the tetraspanin superfamily member CD151, Molecular and Cellular Biology, vol 24, issue 13, American Society for Microbiology, USA, pp. 5978-5988.

Wright, M.D., Moseley, G.W., van Spriel, A.B., 2004, Tetraspanin microdomains in immune cell signalling and malignant disease, Tissue Antigens, vol 64, issue 5, Wiley-Blackwell Publishing, Inc., USA, pp. 533-542.

Moseley, G.W., Jackson, D.E., 2004, The multiple functions of PECAM-1, Australian Biochemist, vol 35, issue 2, Worldwide OnLine Printing, Caulfield South Vic Australia, pp. 9-12.

Lau, L., Wee, J.L., Wright, M.D., Moseley, G.W., Hogarth, P.M., Ashman, L.K., Jackson, D.E., 2004, The tetraspanin superfamily member CD151 regulates outside-in integrin IIb3 signaling and platelet function, Blood, vol 104, issue 8, American Society of Hematology, Washington USA, pp. 2368-2375.

Moseley, G.W., Elliott, J., Wright, M.D., Partridge, L.J., Monk, P.N., 2003, Interspecies contamination of the KM3 cell line: implications for CD63 function in melanoma metastasis, International Journal of Cancer, vol 105, issue 5, Wiley-Liss, Hoboken USA, pp. 613-616.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Immune evasion strategies of Paramyxovirinae: The role of protein trafficking in host-pathogen interactions..

Supervisors:

Jans, D (Joint), Moseley, G (Joint-co).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Mechanisms of viral immune evasion: Nucleocytoplasmic trafficking of Lyssavirus phosphoproteins and their isoforms..

Supervisors:

Jans, D (Joint), Moseley, G (Joint-co).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Nuclear localisation mechanisms and function of the Rabies virus phosphoprotein.

Supervisors:

Jans, D (Joint), Moseley, G (Joint-co).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The role of microtubules in regulating nuclear trafficking: significance to viral biology.

Supervisors:

Jans, D (Joint), Moseley, G (Joint-co).