Prof Robyn O'Hehir - Researcher Profile

Biography

Professor Robyn O’Hehir has been a key international figure in allergy and asthma research and clinical care for over 25 years.  She is an academic clinician scientist who successfully combines a strong track record in basic research with a clear commitment to clinical medicine, in this way demonstrating the value of translational medical research.  The contribution of Professor O’Hehir to the allergy and respiratory field ranges from basic animal studies on the immunology of allergy and T cell epitope mapping, through translational research on novel immunogens designed to invoke protective immunity, to clinical research on the pathophysiology and management of asthma.  She has more than 200 publications.  The importance of her research is reflected by her success in competitive grant funding with an annual personal research budget in excess of $1.5 million.  This includes continuous NHMRC funding (including 21 NHMRC or ARC grants over her career at Monash/Alfred since 1997) and a Co-operative Research Centre for Asthma and Airways.    In 2007 she was honoured by the NHMRC in a publication as one of ten “Great Minds in Australian Research” and in 2010 was made a Life Governor of the Asthma Foundation of Victoria in recognition of 14 years service as a Director of Asthma Victoria.  Professor O’Hehir also contributes to the community through membership of World Allergy Organisation committees, the Anaphylaxis and Asthma State Committees, the Food Standards Authority of Australia and New Zealand Scientific Committee and the Governing Board of Cabrini Health.

Professor O’Hehir currently serves as Editor of the international journal Clinical and Experimental Allergy.  She is regularly invited to give plenary and symposium keynote talks at national and international meetings.  Professor O’Hehir is Director of the Department of Allergy, Immunology and Respiratory Medicine at The Alfred Hospital with 150 staff, studying and treating the full range of allergic and respiratory conditions.  She is noted for offering the highest quality of leadership to a broadly based Department, with strong areas of basic research, clinical research, public health commitment and specialist clinical practice.  She is actively engaged in national and international clinical trials, to ensure that her combined research and clinical duties focus on translation of research findings into improved Hospital and community clinical practice.

Research & Supervision Interests

Professor O’Hehir’s research targets allergy and inflammation, addressing fundamental issues (such as the molecular characterisation of allergens, and regulators of the inflammatory response to allergens) in the context of translation to the clinic, emphasising prevention of harmful clinical outcomes such as anaphylaxis and inflammation-mediated fibrosis.  She has a particular clinical and research interest in grass pollen, peanut and seafood allergy with a view to developing safe and effective diagnostics and immunotherapy for these allergic diseases.   Additionally she has an active translational research program seeking to progress research and clinical trials into the role of follistatin as a therapeutic for inflammatory lung disorders including cystic fibrosis and idiopathic pulmonary fibrosis.

Qualifications

FRCPATH

Institution: Royal College of Pathologists

Year awarded: 2005

FRCP

Institution: Royal College of Physicians

Year awarded: 1995

PHD

Institution: University of London

Year awarded: 1989

FRACP

Institution: Royal Australasian College of Physicians

Year awarded: 1987

MBBS HONS I

Institution: Monash University

Year awarded: 1979

BACHELOR OF SCIENCE

Institution: Monash University

Year awarded: 1975

Publications

Books

O'Hehir, R.E., Berger, W.E., 2003, Asthma and Allergies for Dummies, Wiley Publishing Australia Pty Ltd, Milton Qld Australia.

Book Chapters

O'Hehir, R.E., Sutherland, M.F., Drew, A.C., Rolland, J.M., 2008, Latex Allergy, in Allergy and Allergic Diseases, eds Eds. A.B. Kay, J. Bousquet, P.G. Holt & A.P. Kaplan, Blackwell Publishing, United Kingdom, pp. 1164-1184.

Douglass, J.A., O'Hehir, R., 2000, Asthma: a multisystem disease, in Understanding asthma, MacLennan & Petty, Sydney NSW Australia, pp. 144-152.

O'Hehir, R., Askonas, B., Lamb, J., 1997, T-Cell Cloning, in Allergy and Allergic Diseases, Blackwell Science Ltd., London UK, pp. 755-765.

Journal Articles

Mittag, D., Varese, N., Scholzen, A., Mansell, A.S., Barker, G., Rice, G., Rolland, J.M., O'Hehir, R.E., 2013, TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decreaseinduction of Foxp3hi regulatory T cells, European Journal Of Immunology [P], vol 43, Wiley, Germany, pp. 1-11.

Smith, W.B., O'Hehir, R.E., 2012, ACEI associated angioedema, Australian Family Physician [P], vol 41, issue 3, Royal Australian College of General Practitioners, Australia, p. 89.

Starkl, P., Felix, F., Krishnamurthy, D., Stremnitzer, C., Roth-Walter, F., Prickett, S., Voskamp, A.L., Willensdorfer, A., Szalai, K., Weichselbaumer, M., O'Hehir, R.E., Jensen-Jarolim, E., 2012, An unfolded variant of the major peanut allergen Ara h 2 with decreased anaphylactic potential, Clinical and Experimental Allergy [E], vol 42, issue 12, Blackwell, Germany, pp. 1801-1812.

Chua, J., Douglass, J., Gillman, A., O'Hehir, R.E., Meeusen, E.N.T., 2012, Galectin-10, a Potential Biomarker of Eosinophilic Airway Inflammation, PLoS ONE [P], vol 7, issue 8, PLOS, Online, pp. 1-6.

Amarasekera, M., Gunawardena, N., De Silva, N., Douglass, J., O'Hehir, R.E., Weerasinghe, A., 2012, Impact of helminth infection on childhood allergic disease in an area in transition from high to low infection burden, International Archives Of Allergy And Immunology [P], vol 2, Karger AG, Basel, pp. 122-128.

Van Gramberg, J.L., De Veer, M.J., O'Hehir, R.E., Meeusen, E.N.T., Bischof, R., 2012, Induction of allergic responses to peanut allergen in sheep, PLoS ONE [P], vol 7, issue 12 (Art. No.: e51386), Public Library of Science, USA, pp. 1-6.

Hardy, C., LeMasurier, J., Belz, G., Scalzo-Inguanti, K., Yao, J., Xiang, S., Kanellakis, P., Bobik, A., Strickland, D.H., Rolland, J., O'Hehir, R., Plebanski, M., 2012, Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation, Journal of Immunology [E], vol 188, issue 3, American Association of Immunologists, USA, pp. 1431-1441.

Wardlaw, A.J., O'Hehir, R.E., Corrigan, C.J., Hamid, Q., 2012, Special issue on severe asthma, Clinical and Experimental Allergy [E], vol 42, issue 5, Blackwell Publishing, UK, p. 611.

Hardy, C.L., Nguyen, H.T., Mohamud, R., Yao, J.J., Oh, D.Y., Plebanski, M., Loveland, K.A.L., Harrison, C., Rolland, J.M., O'Hehir, R.E., 2012, The activin A antagonist follistatin inhibits asthmatic airway remodelling., Thorax [P], B M J Group, United Kingdom, pp. 1-10.

de Kretser, D., O'Hehir, R., Hardy, C., Hedger, M., 2012, The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair, Molecular and Cellular Endocrinology [P], vol 359, issue 1-2, Elsevier Ireland Ltd, Ireland, pp. 101-106.

Jayaraj, R., Hales, B., Viberg, L., Pizzuto, S., Holt, D., Holt, D., Rolland, J.M., O'Hehir, R.E., Currie, B.J., Walton, S., 2011, A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei, Diagnostic Microbiology and Infectious Disease [P], vol 71, issue 4, Elsevier, USA, pp. 403-407.

Turner, P.J., Gray, P.E.A., Wong, M., Varese, N., Rolland, J.M., O'Hehir, R.E., Campbell, D., 2011, Anaphylaxis to apple and orange seed, Journal Of Allergy And Clinical Immunology [P], vol 128, issue 6, Elsevier, New York, USA, pp. 1363-1365.

Prickett, S.R., Voskamp, A.L., Dacumos-Hill, A., Symons, K., Rolland, J.M., O'Hehir, R.E., 2011, Ara h 2 peptides containing dominant CD4+ T-cell epitopes: Candidates for a peanut allergy therapeutic, Journal Of Allergy And Clinical Immunology [P], vol 127, issue 3, Mosby, Inc., United States, pp. 608-615.

Glaspole, I.N., De Leon, M., Prickett, S., O'Hehir, R.E., Rolland, J.M., 2011, Clinical Allergy to Hazelnut and Peanut: Identification of T Cell Cross-Reactive Allergens, International Archives Of Allergy And Immunology [P], vol 155, issue 4, Karger, Basel, Switzerland, pp. 345-354.

Davies, J.M., Dang, T., Voskamp, A.L., Drew, A.C., Biondo, M.A., Phung, M.W., Upham, J.W., Rolland, J.M., O'Hehir, R.E., 2011, Functional immunoglobulin E cross-reactivity between Pas n 1 of Bahia grass pollen and other group 1 grass pollen allergens, Clinical and Experimental Allergy [E], vol 41, Blackwell Publishing, United Kingdom, pp. 281-291.

Drew, A.C., Davies, J.M., Dang, T., Rolland, J.M., O'Hehir, R.E., 2011, Purification of the Major Group 1 Allergen from Bahia Grass Pollen, Pas n 1, International Archives Of Allergy And Immunology [P], vol 154, Karger, Basel, Switzerland, pp. 295-298.

Davies, J.M., Voskamp, A.L., Dang, T., Pettit, B., Loo, D., Petersen, A., Hill, M.M., Upham, J.W., Rolland, J.M., O'Hehir, R.E., 2011, The dominant 55 kDa allergen of the subtropical Bahia grass (Paspalum notatum) pollen is a group 13 pollen allergen, Pas n 13, Molecular Immunology [P], vol 48, Elsevier, Netherlands, pp. 931-940.

Allen, K.J., O'Hehir, R.E., 2011, The evolution of oral immunotherapy for the treatment of peanut allergy, Clinical and Experimental Allergy [E], vol 41, Blackwell Publishing, United Kingdom, pp. 1172-1174.

Abdel Rahman, A., Lopata, A.L., O'Hehir, R., Robinson, J., Banoub, J., Helleur, R., 2010, Characterization and de novo sequencing of snow crab tropomyosin enzymatic peptides by both electrospary ionization and matrix-assisted laser desorption ionization QqToF tandemmass spectrometry, Journal of Mass Spectrometry [P], vol 45, issue 4, John Wiley & Sons Ltd, England, pp. 372-381.

Bousquet, J., Schunemann, H., Zuberbier, T., Bachert, C., Baena-Cagnani, C.E., Bousquet, P.J., Brozek, J., Canonica, G.W., Casale, T.B., Demoly, P., Gerth van Wijk, R., Ohta, K., Bateman, E.D., Calderon, M., Cruz, A.A., Dolen, W.K., Haughney, J., Lockey, R.F., Lotvall, J., O'Byrne, P., Spranger, O., Togias, A., Bonini, S., Boulet, L.P., Camargos, P., Carlsen, K.H., Chavannes, N.H., Delgado, L., Durham, S.R., Fokkens, W.J., Fonseca, J., Haahtela, T., Kalayci, O., Kowalski, L., Larenas-Linnemann, D., Li, J., Mohammad, Y., Mullol, J., Naclerio, R., O'Hehir, R.E., Papadopoulos, N., Passalacqua, G., Rabe, K.F., Pawankar, R., Ryan, D., Samolinski, B., Simons, F.E.R., Valovirta, E., Yorgancioglu, A., Yusuf, O.M., Agache, I., Ait-Khaled, N., Annesi-Maesano, I., Beghe, B., Kheder, A.B., Blaiss, M.S., Boakye, D.A., Bouchard, J., Burney, P.G., Busse, W.W., Chan-Yeung, M., Chen, Y., Chuchalin, A.G., Costa, D.J., Custovic, A., Dahl, R., Denburg, J., Douagui, H., Emuzyte, R., Grouse, L., Humbert, M., Jackson, C., Johnston, S.L., Kaliner, A., Keith, P.K., Kim, Y.Y., Klossek, J.M., Kuna, P., Le, L.T., Lemiere, C., Lipworth, B., Mahboub, B., Malo, J.L., Marshall, G.D., Mavale-Manuel, S., Meltzer, E.O., Morais-Almeida, M., Motala, C., Naspitz, C., Nekam, K., Niggemann, B., Nizankowska-Mogilnicka, E., Okamoto, Y., Orru, M.P., Ouedraogo, S., Palkonen, S., Popov, T.A., Price, D., Rosado-Pinto, J., Scadding, G.K., Sooronbaev, T.M., Stoloff, S.W., Toskala, E., Van Cauwenberge, P., Vandenplas, O., Van Weel, C., Viegi, G., Virchow, J.C., Wang, D.Y., Wickman, M., Williams, D., Yawn, B.P., Zar, H.J., Zernotti, M., Zhong, N., 2010, Development and implementation of guidelines in allergic rhinitis - an ARIA-GA2LEN paper, Allergy [P], vol 65, issue 10, Wiley-Blackwell Publishing Ltd, UK, Switzerland, pp. 1212-1221.

Rolland, J., Gardner, L., O'Hehir, R., 2010, Functional regulatory T cells and allergen immunotherapy, Current Opinion In Allergy And Clinical Immunology [P], vol 10, issue 6, Lippincott Williams & Wilkins, USA, pp. 559-566.

Walton, S., Pizzutto, S., Slender, A., Viberg, L., Holt, D., Hales, B., Kemp, D.J., Currie, B., Rolland, J., O'Hehir, R., 2010, Increased allergic immune response to sarcoptes scabiei antigens in crusted versus ordinary scabies, Clinical And Vaccine Immunology [P], vol 17, issue 9, American Society for Microbiology, USA, pp. 1428-1438.

Hardy, C.L., LeMasurier, J., Olsson, F.P., Dang, T., Yao, J.J., Yang, M., Plebanski, M., Phillips, D.J., Mollard, R.A., Rolland, J.M., O'Hehir, R.E., 2010, Interleukin-13 regulates secretion of the tumor growth factor - ? superfamily cytokine activin A in allergic airway inflammation, American Journal Of Respiratory Cell And Molecular ..., vol 42, issue 6, Amercan Thoracic Society, United States, pp. 667-675.

Drew, A.C., Davies, J., Dang, T., Rolland, J., O'Hehir, R., 2010, Purification of the major group 1 allergen from bahia grass pollen, Pas n 1, International Archives Of Allergy And Immunology [P], vol 154, issue 4, S. Karger AG, Switzerland, pp. 295-298.

Lopata, A.L., O'Hehir, R., Lehrer, S.B., 2010, Shellfish allergy, Clinical And Experimental Allergy [P], vol 40, issue 6, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 850-858.

Mittag, D., Scholzen, A., Varese, N.P., Baxter, L., Paukovics, G., Harrison, L., Rolland, J., O'Hehir, R., 2010, The effector T cell response to ryegrass pollen Is counterregulated by simultaneous induction of regulatory T cells, Journal Of Immunology [P], vol 184, issue 9, American Association of Immunologists, USA, pp. 4708-4716.

Rolland, J.M., Gardner, L.M., O'Hehir, R.E., 2009, Allergen-related approaches to immunotherapy, Pharmacology & Therapeutics, vol 121, issue Dec 7, Elsevier Inc, United States, pp. 273-284.

O'Hehir, R.E., Gardner, L.M., De Leon, M., Hales, B., Biondo, M., Douglass, J.A., Rolland, J.M., Sandrini Lopes de Souza, A., 2009, House dust mite sublingual immunotherapy: The role for transforming growth factor-beta and functional regulatory T cells, American Journal Of Respiratory And Critical Care M..., vol 180, issue 10, American Thoracic Society, United States, pp. 936-947.

Goeman, D.P., Sanci, L.A., Scharf, S.L., Bailey, M.J., O'Hehir, R.E., Jenkins, C., Douglass, J.A., 2009, Improving general practice consultations for older people with asthma: A cluster randomised control trial, Medical Journal Of Australia [P], vol 191, issue 2, Australasian Medical Publishing Company Pty. Ltd, Australia, pp. 113-117.

Douglass, J.A., Carroll, K., Voskamp, A.L., Bourke, P., Wei, A., O'Hehir, R.E., 2009, Omalizumab is effective in treating systemic mastocytosis in a nonatopic patient, Allergy [P], vol E, Wiley-Blackwell Publishing Ltd, United Kingdom, Switzerland, pp. 1-2.

O'Hehir, R.E., 2009, Treating allergy: Where to from here?, Internal Medicine Journal [E], vol 39, issue 8, Wiley-Blackwell Publishing Asia, Australia, pp. 491-494.

Bousquet, J., Bachert, C., Canonica, G.W., Casale, T.B., Cruz, A.A., Lockey, R.J., Zuberbier, T., O'Hehir, R.E., 2009, Unmet needs in severe chronic upper airway disease (SCUAD), Journal Of Allergy And Clinical Immunology [P], vol 124, issue 3, Mosby, Inc., United States, pp. 428-433.

Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A., Zuberbier, T., Baena-Cagnani, C.E., Canonica, G.W., Weel, C., Agache, I., Ait-Khaled, N., Bachert, C., Blaiss, M.S., Bonini, S., Boulet, L.P., Bousquet, P.J., Camargos, P., Carlsen, K.H., Chen, Y., Custovic, A., Dahl, R., Demoly, P., Douagui, H., Durham, S.R., Wijk, R.G.v., Kalayci, O., Kaliner, A., Kim, Y.Y., Kowalski, L., Kuna, P., Le, L.T., Lemiere, C., Li, J., Lockey, R.F., Mavale-Manuel, S., Meltzer, E.O., Mohammad, Y., Mullol, J., Naclerio, R., O'Hehir, R.E., Ohta, K., Ouedraogo, S., Palkonen, S., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T.A., Rabe, K.F., Rosado-Pinto, J., Scadding, G.K., Simons, F.E.R., Toskala, E., Valovirta, E., van Cauwenberge, P., Wang, D.Y., Wickman, M., Yawn, B.P., Yorgancioglu, A., Yusuf, O.M., Zar, H., 2008, Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update, Allergy [P], vol 63, issue Suppl 86, Wiley-Blackwell Publishing Ltd, United Kingdom, Switzerland, pp. 8-160.

Nolan, R.C., Puy, R., Deckert, K., O'Hehir, R.E., Douglass, J.A., 2008, Experience with a new commercial skin testing kit to identify IgE-mediated penicillin allergy, Internal Medicine Journal, vol 38, issue 5, Wiley-Blackwell Publishing Asia, Australia, pp. 357-361.

Wrobel, J.P., O'Hehir, R.E., Douglass, J.A., 2008, Food allergy in adults: An over- or underrated problem? [Nahrungsmittelallergie bei erwachsenen - Uber- oder unterschatzt?], Australian Family Physician, vol 105, issue 4, Royal Australian College of General Practitioners, Australia, pp. 715-723.

Davies, J.M., O'Hehir, R.E., 2008, Immunogenetic characteristics of immunoglobulin E in allergic disease, Clinical and Experimental Allergy, vol 38, issue 4, Blackwell Publishing, United Kingdom, pp. 566-578.

Rolland, J.M., O'Hehir, R.E., 2008, Latex allergy: a model for therapy, Clinical and Experimental Allergy, vol 38, issue 6, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 898-912.

Davies, J., Mittag, D., Dang, T., Symons, K., Voskamp, A.L., Rolland, J.M., O'Hehir, R.E., 2008, Molecular cloning, expression and immunological characterisation of Pas n 1, the major allergen of Bahia grass Paspalum notatum pollen, Molecular Immunology, vol 46, issue 2, Pergamon, United Kingdom, pp. 286-293.

Rolland, J.M., Apostolou, E., De Leon, M., Stockley, C.S., O'Hehir, R.E., 2008, Specific and sensitive enzyme-linked immunosorbent assays for analysis of residual allergenic food proteins in commercial bottled wine fined with egg white, milk, and nongrape-derived tannins, Journal of Agricultural and Food Chemistry, vol 56, American Chemical Society, USA, pp. 349-354.

Glaspole, I.N., De Leon, M., Rolland, J.M., O'Hehir, R.E., 2007, Anaphylaxis to lemon soap: citrus seed and peanut allergen cross-reactivity, Annals of Allergy, Asthma and Immunology, vol 98, issue 3, American College of Allergy Asthma and Immunology, USA, pp. 286-289.

De Leon, M., Drew, A.C., Glaspole, I.N., Suphioglu, C., O'Hehir, R.E., Rolland, J.M., 2007, IgE cross-reactivity between the major peanut allergen Ara h 2 and tree nut allergens, Molecular Immunology, vol 44, issue March 2006, Pergamon, UK, pp. 463-471.

O'Hehir, R.E., Douglass, J.A., 2007, Risk-minimisation strategies for peanut allergy, Invalid Code, vol 370, issue 9586, The Lancet Publishing Group, United Kingdom, p. 483.

O'Hehir, R.E., Sandrini Lopes de Souza, A., Anderson, G.P., Rolland, J.M., 2007, Sublingual allergen immunotherapy: Immunological mechanisms and prospects for refined vaccine preparations, Current Medicinal Chemistry, vol 14, issue 21, Bentham Science Publishers Ltd, The Netherlands, pp. 2235-2244.

De Leon, M., Rolland, J.M., O'Hehir, R.E., 2007, The peanut allergy epidemic: allergen molecular characterisation and prospects for specific therapy, Expert Reviews in Molecular Medicine, vol 9, issue 1, Cambridge university press, United Kingdom, pp. 1-18.

Goeman, D.P., O'Hehir, R.E., Jenkins, C., Scharf, S.L., Douglass, J.A., 2007, 'You have to learn to live with it': a qualitative and quantitative study of older people with asthma, The Clinical Respiratory Journal [P], vol 1, issue 2, Wiley-Blackwell Munksgaard, United Kingdom, pp. 99-105.

Douglass, J.A., O'Hehir, R.E., 2006, 1. Diagnosis, treatment and prevention of allergic disease: the basics, Medical Journal of Australia, vol 185, issue 4, Australasian Medical Publishing Company Pty. Ltd, Australia, pp. 228-233.

Kedda, M., Duffy, D.L., Bradley, B., O'Hehir, R.E., Thompson, P.J., 2006, ADAM33 haplotypes are associated with asthma in a large Australian population, European Journal of Human Genetics, vol 14, issue 9, Nature Publishing Group, UK, pp. 1027-1036.

Apostolou, E., Deckert, K., Puy, R., Sandrini, A., De Leon, M., Douglass, J.A., Rolland, J.M., O'Hehir, R.E., 2006, Anaphylaxis to Gelofusine(R) confirmed by in vitro basophil activation test: a case series, Anaesthesia, vol 61, issue 3, Blackwell Publishing Ltd, UK, pp. 264-268.

Hardy, C.L., O'Connor, A.E., Yao, J.(., Sebire, K., de Kretser, D.M., Rolland, J.M., Anderson, G., Phillips, D.J., O'Hehir, R.E., 2006, Follistatin is a candidate endogenous negative regulator of Activin A in experimental allergic asthma, Clinical and Experimental Allergy, vol 36, issue 7, Blackwell Scientific Publications, UK, pp. 941-950.

Stockley, C., O'Hehir, R.E., Rolland, J.M., 2006, Is allergen labelling necessary for Australian wine?, Australian and New Zealand Wine Industry Journal, vol 21, issue 3, Wine Publishers Pty. Ltd, Australia, pp. 17-21.

Rolland, J.M., Apostolou, E., Deckert, K., De Leon, M., Douglass, J.A., Glaspole, I.N., Bailey, M.J., Stockley, C., O'Hehir, R.E., 2006, Potential food allergens in wine: double-blind, placebo-controlled trial and basophil activation analysis, Nutrition, vol 22, issue 9, Elsevier Inc., USA, pp. 882-888.

Nolan, R.C., De Leon, M., Rolland, J.M., Koh, R.K., O'Hehir, R.E., 2006, What's in a kiss: peanut allergen transmission as a sensitizer?, Journal of Allergy and Clinical Immunology, vol 119, issue 3, Mosby-Elsevier, New York USA, p. 755.

Drew, A.C., Eusebius, N.P., Kenins, L., De Silva, H.D., Suphioglu, C., Rolland, J.M., O'Hehir, R.E., 2005, A candidate vaccine for specific immunotherapy in latex allergy: hypoallergenic variants of Hev b 6.01, Allergy and Clinical Immunology International: Journal of the World Allergy Organization, vol Supp 2, issue Supp 2, Hogrefe & Huber Publishers, USA, pp. 222-225.

Rolland, J.M., Drew, A.C., O'Hehir, R.E., 2005, Advances in development of hypoallergenic latex immunotherapy, Current Opinion in Allergy and Clinical Immunology, vol 5, issue 6, Lippincott, Williams & Wilkins, USA, pp. 544-551.

Davies, J.M., Bright, M.L., Rolland, J.M., O'Hehir, R.E., 2005, Bahia grass pollen specific IgE is common in seasonal rhinitis patients but has limited cross-reactivity with Ryegrass, Allergy, vol 60, issue 2, Blackwell Munksgaard, Denmark, pp. 251-255.

Glaspole, I.N., De Leon, M., Rolland, J.M., O'Hehir, R.E., 2005, Characterization of the T-cell epitopes of a major peanut allergen, Ara h 2, Allergy: European Journal of Allergy and Immunology, vol 60, issue 1, Blackwell Munksgaard, Denmark, pp. 35-40.

Rolland, J.M., O'Hehir, R.E., 2005, Detection of the major latex allergen Hev b 6.02 in low-allergen latex gloves, Tissue Antigens, vol 66, issue 5, Blackwell Publishing, Oxford England, p. 401.

De Leon, M.P., Drew, A.C., Glaspole, I.N., Suphioglu, C., Rolland, J.M., O'Hehir, R.E., 2005, Functional analysis of cross-reactive immunoglobulin E antibodies: peanut-specific immunoglobulin E sensitizes basophils to tree nut allergens, Clinical and Experimental Allergy, vol 35, issue 8, Blackwell Publishing Ltd, UK, pp. 1056-1064.

Hardy, C.L., Rolland, J.M., O'Hehir, R.E., 2004, Blocking antibodies in allergen immunotherapy: the Yin and Yang, Clinical and Experimental Allergy, vol 34, issue 4, Blackwell Publishing Ltd, UK, pp. 510-512.

Gardner, L.M., O'Hehir, R.E., Rolland, J.M., 2004, High dose allergen stimulation of T cells from house dust mite-allergic subjects induces expansion of IFN-+ T cells, apoptosis of CD4+IL-4+ T cells and T cell anergy, International Archives of Allergy and Immunology, vol 133, issue 1, S. Karger AG, Switzerland, pp. 1-13.

Drew, A.C., Eusebius, N.P., Kenins, L., De Silva, H.D., Suphioglu, C., Rolland, J.M., O'Hehir, R.E., 2004, Hypoallergenic variants of the major latex allergen Hev b 6.01 retaining human T lymphocyte reactivity, The Journal of Immunology, vol 173, issue 9, American Association of Immunologists, USA, pp. 5872-5879.

Gardner, L.M., Spyroglou, L.G., O'Hehir, R.E., Rolland, J.M., 2004, Increased allergen concentration enhances IFN- production by allergic donor T cells expressing a peripheral tissue trafficking phenotype, Allergy, vol 59, issue 12, Blackwell Munksgaard, Denmark, pp. 1308-1317.

Gardner, L.M., Thien, F., Douglass, J.A., Rolland, J.M., O'Hehir, R.E., 2004, Induction of T 'regulatory' cells by standardized house dust mite immunotherapy: an increase in CD4+CD25+ interleukin-10+ T cells expressing peripheral tissue trafficking markers, Clinical and Experimental Allergy, vol 34, issue 8, Blackwell Publishing Ltd, UK, pp. 1209-1219.

de Silva, H.D., Gardner, L.M., Drew, A.C., Beezhold, D.H., Rolland, J.M., O'Hehir, R.E., 2004, The hevein domain of the major latex-glove allergen Hev b 6.01 contains dominant T cell reactive sites, Clinical and Experimental Allergy, vol 34, issue 4, Blackwell Publishing Ltd, UK, pp. 611-618.

Beezhold, D.H., Hickey, V.L., Sutherland, M.F., O'Hehir, R.E., 2004, The latex allergen Hev b 5 is an antigen with repetitive murine B-cell epitopes, International Archives of Allergy and Immunology, vol 134, issue 4, S. Karger AG, Switzerland, pp. 334-340.

Petrovska, N., Wu, X., Donato, R., Wang, Z., Ong, E.K., Jones, E., Forester, J., Emmerling, M., Sidoli, A., O'Hehir, R.E., Spangenberg, G.C., 2004, Transgenic ryegrasses (Lolium spp.) with down-regulation of main pollen allergens, Molecular Breeding: New Strategies in Plant Improvement, vol 14, Springer-Verlag Dordrecht, Netherlands, pp. 489-501.

Davies, J.M., O'Hehir, R.E., 2004, VH gene usage in immunoglobulin E responses of seasonal rhinitis patients allergic to grass pollen is oligoclonal and antigen driven, Clinical and Experimental Allergy, vol 34, issue 3, Blackwell Publishing Ltd, UK, pp. 429-436.

Douglass, J.A., O'Hehir, R.E., 2003, Adrenaline and non-life threatening allergic reactions: Intramuscular adrenaline is safe, BMJ (Clinical research ed.) [P], vol 327, BMJ Group, United Kingdom, pp. 226-227.

Hardy, C.L., Kenins, L., Drew, A.C., Rolland, J.M., O'Hehir, R.E., 2003, Characterization of a mouse model of allergy to a major occupational latex glove allergen Hev b 5, American Journal of Respiratory and Critical Care Medicine, vol 167, issue 10, American Lung Association, USA, pp. 1393-1399.

Tharp, M., O'Hehir, R.E., Renwick, A.G., Testa, B., 2003, Consensus Group on New-Generation Antihistamines (CONGA): Present status and recommendations. Panel 4: Lack of drug-drug interactions, Clinical And Experimental Allergy [P], vol 33, issue 9, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 1316-1317.

Douglass, J.A., O'Hehir, R.E., 2003, Emergency treatment of asthma: how are we doing?, Internal Medicine Journal, vol 33, issue 9-10, Blackwell Publishing Asia, Carlton Vic Australia, pp. 401-403.

De Leon, M.P., Glaspole, I.N., Drew, A.C., Rolland, J.M., O'Hehir, R.E., Suphioglu, C., 2003, Immunological analysis of allergenic cross-reactivity between peanut and tree nuts, Clinical and Experimental Allergy, vol 33, issue 9, Blackwell Publishing Ltd, Oxford UK, pp. 1273-1280.

Gruehn, S., Suphioglu, C., O'Hehir, R.E., Volkmann, D., 2003, Molecular cloning and characterization of hazel pollen protein (70 kD) as a luminal binding protein (BiP): a novel cross-reactive plant allergen, International Archives of Allergy and Immunology, vol 131, issue 2, S. Karger AG, Switzerland, pp. 91-100.

Haque, S., Boyce, N., Thien, F., O'Hehir, R.E., Douglass, J.A., 2003, Role of intravenous immunoglobulin in severe steroid-dependant asthma, Internal Medicine Journal, vol 33, Blackwell Publishing Asia, Australia, pp. 341-344.

Gardner, L.M., O'Hehir, R.E., Rolland, J.M., 2003, T cell targeted allergen derivatives for improved efficacy and safety of specific immunotherapy for allergic disease, Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, vol 2, issue 4, Bentham Science Publishers Ltd, The Netherlands, pp. 351-365.

Rolland, J.M., O'Hehir, R., 2002, Allergen immunotherapy: Current and new therapeutic strategies, Allergology International, vol 51, Blackwell Publishing Asia, Australia, pp. 221-231.

Burton, M.D., Papalia, L., Eusebius, N.P., O'Hehir, R., Rolland, J.M., 2002, Characterization of the human T cell response to rye grass pollen allergens Lol p 1 and Lol p 5, Allergy, vol 57, issue 12, Blackwell Munksgaard, Copenhagen Denmark, pp. 1136-1144.

O'Hehir, R., 2002, Immunology and allergy, Medical Journal of Australia, vol 176, issue 1, Australasian Medical Publishing Co Ltd, Sydney NSW Australia, p. 22.

Sutherland, M.F., Suphioglu, C., Rolland, J.M., O'Hehir, R., 2002, Latex allergy: towards immunotherapy for health care workers, Clinical and Experimental Allergy, vol 32, issue 5, Blackwell Publishing Ltd, Oxford UK, pp. 667-673.

Eusebius, N.P., Papalia, L., Suphioglu, C., McLellan, S.C., Varney, M., Rolland, J.M., O'Hehir, R., 2002, Oligoclonal Analysis of the Atopic T Cell Response to the Group 1 Allergen of Cynoden dactylon (Bermuda Grass) Pollen: Pre- and Post-Allergen-Specific Immunotherapy, International Archives of Allergy and Immunology, vol 127, issue 3, Karger, Basel Switzerland, pp. 234-244.

Mitakakis, T., Tovey, E.R., Yates, D.H., Toelle, B.G., Johnson, A., Sutherland, M.F., O'Hehir, R., Marks, G.B., 2002, Particulate masks and non-powdered gloves reduce latex allergan inhaled by healthcare workers, Clinical and Experimental Allergy, vol 32, issue 8, Blackwell Publishing Ltd, Oxford UK, pp. 1166-1169.

Douglass, J.A., O'Hehir, R.E., 2002, Specific allergen immunotherapy: time for alternatives?, Clinical and Experimental Allergy, vol 32, issue 1, Blackwell Publishing Ltd., UK, pp. 1-3.

Sutherland, M.F., Drew, A., Rolland, J.M., Slater, J.E., Suphioglu, C., O'Hehir, R., 2002, Specific monoclonal antibodies and human immunoglobin e show that Hev b 5 is an abundant allergen in high protein powdered latex gloves, Clinical and Experimental Allergy, vol 32, issue 4, Blackwell Publishing Ltd, Oxford UK, pp. 583-589.

Suphioglu, C., Schappi, G.F., Kenrick, J., Levy, D., Davies, J.M., O'Hehir, R., 2001, A novel grass pollen allergen mimotype identified by phage display peptide library inhibits allergen-human IgE antibody interaction, FEBS Letters, vol 502, issue 1-2, Elsevier Science BV, Amsterdam Netherlands, pp. 46-52.

Levy, D., Davies, J.M., O'Hehir, R., Suphioglu, C., 2001, A rapid and efficient two-step gel electrophoresis method for the purification of major rye grass pollen allergens, Electrophoresis, vol 22, issue 10, Wiley - V C H Verlag GMBH, Berlin Germany, pp. 1900-1905.

Westall, G.P., Thien, F., Czarny, D., O'Hehir, R.E., Douglass, J.A., 2001, Adverse events associated with rush hymenoptera venom immunotherapy, Medical Journal of Australia, vol 174, Australasian Medical Publishing Company Pty. Ltd., Australia, pp. 227-230.

Knight, B.A., Puy, R., Douglass, J.A., O'Hehir, R.E., Thien, F., 2001, Chlorhexidine anaphylaxis: a case report and review of the literature, Internal Medicine Journal, vol 31, Blackwell Publishing Asia, Australia, p. 436.

Rolland, J.M., O'Hehir, R., 2001, Targeting the allergen- specific CD4+ T Cell - Strategies for improved allergen immunotherapy, Allergy and Clinical Immunology International, vol 13, issue 4, Hogrefe & Huber Publishers, USA, pp. 170-177.

Rolland, J.M., Douglass, J., O'Hehir, R., 2000, Allergen immunotheraphy: current and new therapeutic strategies, Expert Opinion on Investigational Drugs, vol 9 issue 3, Ashley Publications, London UK, pp. 515-527.

De Silva, H., Sutherland, M.F., Suphioglu, C., McLellan, S.C., Slater, J.E., Rolland, J.M., O'Hehir, R., 2000, Human T-cell epitopes of the latex allergen Hev b 5 in health care workers, Journal of Allergy & Clinical Immunology, vol 105, Mosby, Inc., St Louis MO USA, pp. 1017-1024.

Davies, J.M., O'Hehir, R., Suphioglu, C., 2000, Use of Phage display technology to investigate allergen-antibody interactions, Journal of Allergy Clinical Immunology, vol 105, Mosby Inc, St Louis USA, pp. 1085-1092.

Douglass, J., O'Hehir, R., 2000, What determines asthma phenotype?, American Journal of Respiratory and Critical Care Medicine, vol 161, American Thoracic Society, New York NY USA, pp. S211-S214.

Thien, F.P., Douglass, J., O'Hehir, R., 1999, Asthma, Check Program of Self Assessment, vol 328, Royal Australian College of General Practitioners, South Melbourne Vic Australia, pp. 3-17.

Sutherland, M.F., O'Hehir, R., Czarny, D., Suphioglu, C., 1999, Macadamia nut anaphylaxis: Demonstration of specific IgE reactivity and partial cross-reactivity with hazelnut, Journal of Allergy and Clinical Immunology, vol 104, Mosby-year book inc, St Louis USA, pp. 889-890.

Sutherland, M.R., O'Hehir, R., Czarny, D., Suphioglu, C., 1999, Macadamia nut anaphylaxis: Demonstration of specific IgE reactivity and partial cross-reactivity with hazelnut, Journal of Allergy and Clinical Immunology, vol 104, Mosby Inc., St Louis USA, pp. 889-890.

Suphioglu, C., Mawdsley, D., Schappi, G.F., Gruehn, S., De Leon, M., Rolland, J.M., O'Hehir, R., 1999, Molecular cloning, expression and immunological characterisation of Lol p 5C, a novel allergen isoform of rye grass pollen demonstrating high IgE reactivity, Federation of European Biochemical Societies - Letters, vol 462, Elsevier Science, Amsterdam Netherlands, pp. 435-441.

Slater, J.E., Paupore, E.J., O'Hehir, R., 1999, Murine B-cell and T-cell epitopes of the allergen Hev b 5 from natural rubber latex, Molecular Immunology, vol 36, Pergamon-Elsevier Science LTD, Oxford England, pp. 135-143.

O'Hehir, R., Douglass, J., 1999, Stinging insect allergy, Medical Journal of Australia, vol 171, Australasian Medical Publishing, North Sydney NSW Australia, pp. 649-650.

Burton, M.D., Blaher, B., Suphioglu, C., O'Hehir, R., Carbone, F.R., Rolland, J.M., 1999, T-Cell Receptor Contact and MHC Binding Residues of a Major Rye Grass Pollen Allergen T-Cell Epitope, The Journal of Allergy and Clinical Immunology, vol 103:2, Mosby - Year Book Inc, St Louis USA, pp. 255-261.

Rolland, J.M., O'Hehir, R., 1999, Turning off the T-cells: Peptides for Treatment of Allergic Diseases, Today's Life Science, Reed Business Information, Chatswood NSW Australia, pp. 28-35.

Rolland, J.M., O'Hehir, R., 1998, Immunotherapy of allergy: anergy, deletion, and immune deviation, Current Opinion in Immunology, vol 10 (6), Current Biology Publications, London UK, pp. 640-645.

Douglas, R., Weiner, J., Abramson, M.J., O'Hehir, R., 1998, Prevalence of severe anti-venom allergy in southeastern Australia, Journal of Allergy and Clinical Immunology, vol 101 (1), Mosby-Year Book Inc, St Louis USA, pp. 129-131.

Douglas, R., O'Hehir, R., 1997, Peanut allergy: education, avoidance and adrenaline are the mainstays of management, Medical Journal of Australia, vol 166, Asutralasian Medical Publishing Co Ltd, Sydney NSW Australia, pp. 63-64.

Douglas, R., Morton, J., Czarny, D., O'Hehir, R.E., 1997, Prevalence of IgE-mediated allergy to latex in hospital nursing staff, Australian and New Zealand Journal of Medicine, vol 27, Adis International Pty Ltd, Frenchs Forest NSW Australia, pp. 165-169.

Glaspole, I., Douglass, J., Czarny, D., O'Hehir, R., 1997, Stinging insect allergies: Assessing and managing, Australian Family Physician - Bites and Stings, vol 26, RACGP, Sydney NSW Australia, pp. 1395-1399.

Conference Proceedings

Davies, J., Dang, T., Pettit, B., Voskamp, A.L., Rolland, J.M., O'Hehir, R.E., 2009, Characterisation of the group 13 pollen allergen of the subtropical bahia grass, Paspalum notatum, Allergy, June 6-10, Wiley-Blackwell Publishing Ltd, United Kingdom, Switzerland, pp. 108-109.

Li, S., Rolland, J.M., Paukovics, G., Douglass, J.A., Baxter, L., Deckert, K., Suphioglu, C., Weiner, J.M., O'Hehir, R.E., 2007, Induction of Regulatory T Cells by Cynodon dactylon-specific allergen immunotherapy, Allergy and Clinical Immunology International: Journal of the World Allergy Organization, 5-10 May 2006, Hogrefe and Huber Publishers, USA, pp. 1-5.

Burton, M.D., Blaher, B., Suphioglu, C., O'Hehir, R.E., Carbone, F.R., Rolland, J.M., 1997, Identification of MHC and TCR contact residuesof a major rye grass pollen T cell epitope, The Alfred Science Symposium, Melbourne 14/11/97, The Alfred, Melbourne Vic Australia, pp. 45-46.

O'Hehir, R.E., Rolland, J.M., 1997, Peptide Therapy in Allergic Diseases, 5th West pacific Allergy Symposium, 11-14/6/97, West Pacific allergy Symposium, Seoul Korea.

Rolland, J.M., O'Hehir, R.E., 1997, Peptide immunotherapy for allergic disease, The Australasian Society for Immunology Inc. 27th Annual Meeting, Perth 31 Nov-4 Dec 1997, ASI Inc., Perth WA Australia, p. 36.

O'Hehir, R.E., Rolland, J.M., 1997, T cells and allergy: Changes during immunotherapy, Mucosal Solutions, Sydney 27-31/1/97, University of Sydney, Sydney NSW Australia, pp. 59-70.

O'Hehir, R., Rolland, J.M., 1997, T cells and allergy: changes during immunotherapy, Mucosal Solutions, Advances in Mucosal Immunology, Sydney, Australia, 27-31 January 1997, University of Sydney, Sydney NSW Australia, pp. 59-70.

Other

O'Hehir, R., Rolland, J., 2010, IMMUNOTHERAPEUTIC AND IMMUNOPROPHYLACTIC REAGENTS, AUSTRALIA.

de Kretser, D.M., Phillips, D.J., Jones, K.J., O'Hehir, R.E., Patella, S., Wilson, K.M., Sebire, K.L., 2004, Therapeutic method.

Rolland, J.M., O'Hehir, R., 1998, Immunotherapy of allergy: anergy, deletion, and immune deviation, Current Opinion in Immunology, vol 10, Elsevier Science Ltd, London UK, pp. 640-645.

Douglass, J.A., Thien, F.C., O'Hehir, R., 1997, Immunotherapy in Asthma, Thorax, vol 52, BMJ Publishing Group, London UK, pp. 22-29.

Grants

Title:

Abi Prism Tm 7700 Sequence Detection System - Equipment Grant 2000.

Investigators:

Thomson, N, O'Hehir, R, Wesselingh, S, Toh, B, Walters, E

Funding:

(2001 - 2001). National Health & Medical Research Council (NHMRC).

(2001 - 2015). Monash University.

(2001 - 2015). Wellcome Trust.

Title:

BD Biosciences FACSAria flow cytometer.

Investigators:

Rolland, J, Lewin, S, O'Hehir, R, Wesselingh, S, Jackson, S, Toh, B, Crowe, S

Funding:

(2005 - 2009). National Health & Medical Research Council (NHMRC).

Title:

CRC - Project 4 - Immunomodulation.

Investigators:

O'Hehir, R

Funding:

(2010 - 2014). Cooperative Research Centres (CRC).

Title:

CRC Asthma.

Investigators:

O'Hehir, R

Funding:

(2000 - 2004). Cooperative Research Centres (CRC).

(2005 - 2009). Cooperative Research Centres (CRC).

Title:

CRC for Asthma & Airways.

Investigators:

O'Hehir, R

Funding:

Title:

Clinical and Cellular Characterisation of Allergic Disease in Man.

Investigators:

O'Hehir, R

Funding:

(1997 - 2001). Australian Allergy Foundation.

Title:

Couch Grass Allergy: Cellular and Molecular Studies Directed At Improved Specific Immunotherapy.

Investigators:

O'Hehir, R, Suphioglu, C, Rolland, J

Funding:

(2002 - 2004). National Health & Medical Research Council (NHMRC).

Title:

Down-regulating Th2-type allergen-specific responses by antigen.

Investigators:

Rolland, J, O'Hehir, R, Gardner, L

Funding:

(2001 - 2001). Alfred Hospital Research Trust.

Title:

Epitopes of a Major Latex Allergen and Mutagenesis to Express Hypoallergenic Variants for Immunotherapy.

Investigators:

O'Hehir, R, Rolland, J, Suphioglu, C

Funding:

(1999 - 2001). National Health & Medical Research Council (NHMRC).

Title:

Follistatin Therapy for Cystic Fibrosis and other lung inflammatory diseases.

Investigators:

O'Hehir, R, Mackay-Fisson, F, Hardy, C, Rolland, J

Funding:

(2010 - 2013). CASS Foundation Limited.

(2011 - 2015). CASS Foundation Limited.

Title:

Follistatin effects on mucus secretion in transgenic mice.

Investigators:

O'Hehir, R

Funding:

(2012 - 2017). Paranta Biosciences Limited.

Title:

Gene-amp Pcr System 2400 - Equipment Request.

Investigators:

O'Hehir, R, Suphioglu, C

Funding:

(2002 - 2002). Collier Charitable Fund.

(2002 - 2006). Monash University.

Title:

Grass Pollens Allergens.

Investigators:

O'Hehir, R

Funding:

( - ). Autogen Research Pty Ltd.

Title:

Human CD4+ T-cell epitope-based therapeutic for peanut allergy.

Investigators:

O'Hehir, R, Rolland, J

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Title:

Immunoglobulin epsilon VH gene usage and cross reactivity in allergic disease.

Investigators:

O'Hehir, R, Davies, J

Funding:

(2002 - 2007). Monash University.

(2002 - 2010). Monash University.

Title:

Immunological and Molecular Basis of Anaphylaxis Caused By Peanut and Tree Nut Allergy (gms Id 000403).

Investigators:

O'Hehir, R, Rolland, J

Funding:

(2000 - 2002). National Health & Medical Research Council (NHMRC).

Title:

Impaired respiratory tolerance in obesity - the link with asthma?.

Investigators:

O'Hehir, R, Rolland, J, Bruce, C, Hardy, C

Funding:

(2012 - 2016). National Health & Medical Research Council (NHMRC).

Title:

Induction of regulatory T cell responses to inhibit 'anaphylactic'-type immune responses to nut allergens.

Investigators:

O'Hehir, R

Funding:

(2007 - 2011). Ilhan Food Allergy Foundation.

Title:

Inhibition of allergic airway inflammation by nanoparticles.

Investigators:

Plebanski, M, O'Hehir, R, Hardy, C, Rolland, J

Funding:

(2008 - 2011). National Health & Medical Research Council (NHMRC).

Title:

Mechanisms of nanoparticle-mediated inhibition of asthma.

Investigators:

Plebanski, M, O'Hehir, R, Hardy, C, Friend, J, Rolland, J

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Title:

Microplate Scintillation & Luminescence Counter (packard Topcount Nxt).

Investigators:

Gleeson, P, Thomson, N, O'Hehir, R, Walters, E, Stein-Oakley, A

Funding:

(2000 - 2000). National Health & Medical Research Council (NHMRC).

(2000 - 2004). Monash University.

Title:

Modulation of T Cell Response to House Mite Dust Allergens By Peptides.

Investigators:

O'Hehir, R

Funding:

(1998 - 1998). Alfred Healthcare Group Research Award.

Title:

Molecular determinants of an allergic response.

Investigators:

O'Hehir, R

Funding:

(2009 - 2013). Australian Research Council (ARC).

Title:

Purchase of Abi Prism Tm 7700 Sequence Detection System.

Investigators:

Thomson, N, O'Hehir, R, Wesselingh, S, Toh, B, Walters, E

Funding:

(2001 - 2003). Wellcome Trust (UK).

Title:

The interface between innate and adaptive immunity in allergy and asthma. ID: 334000.

Investigators:

O'Hehir, R, Anderson, G, Hamilton, J, Rolland, J

Funding:

(2005 - 2009). National Health & Medical Research Council (NHMRC).

Title:

The use of follistatin to treat the reperfusion injury in organ transplants.

Investigators:

de Kretser, D, O'Hehir, R

Funding:

(2012 - 2016). CASS Foundation Limited.

Title:

Uvp Bioimaging Chemi System - Equipment Grant 2000.

Investigators:

Suphioglu, C, O'Hehir, R, Toh, B

Funding:

(2001 - 2001). National Health & Medical Research Council (NHMRC).

Title:

Activin: a key driver of inflammation and remodelling in chronic airways disease ID: 334087.

Investigators:

O'Hehir, R, Hardy, C, Wilson, J

Funding:

(2005 - 2009). National Health & Medical Research Council (NHMRC).

Title:

Clinical and immunological evaluation of sublingual versus subcutaneous immunotherapy for house dust mite allergy ID: 334086.

Investigators:

O'Hehir, R, Douglass, J, Rolland, J

Funding:

(2005 - 2009). National Health & Medical Research Council (NHMRC).

Title:

Physiological aetiology of Refractory Asthma.

Investigators:

Thompson, B, Thien, F, Douglass, J, King, G, O'Hehir, R

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Postgraduate Research Supervisions

Completed Supervision

Student:

De Leon, M.

Program of Study:

IMMUNOLOGICAL AND MOLECULAR CHARACTERISATION OF MAJOR PEANUT ALLERGENS AND THEIR CROSS-REACTIVE COMPONENTS IN TREE NUTS. (PHD) 2004.

Supervisors:

O''Hehir, R (Main), Rolland, J (Associate), Suphioglu, C (Associate).

Student:

Eusebius, N.

Program of Study:

The Human T Cell Response to the Major Bermuda Grass Pollen Allergen, Cyn d 1. (Masters) 2004.

Supervisors:

O''Hehir, R (Main), Rolland, J (Associate), Suphioglu, C (Associate).

Student:

Gardner, L.

Program of Study:

MODULATION OF THE ALLERGEN-SPECIFIC T CELL RESPONSE. (PHD) 2003.

Supervisors:

O''Hehir, R (Joint), Rolland, J (Joint-Co).

Student:

Glaspole, I.

Program of Study:

THE HUMAN CELLULAR RESPONSE TO PEANUT (ARACHIS HYPOGAEA) AND CROSS-REACTING TREE-NUTS. (PHD) 2004.

Supervisors:

O''Hehir, R (Joint-Co), Rolland, J (Joint).

Student:

Goeman, D.

Program of Study:

Improving the style and content of general practice consultations for older people with asthma. (PHD) 2011.

Supervisors:

Douglass, J (Main), O''Hehir, R (Associate).

Student:

Holzer, K.

Program of Study:

EXERCISE-INDUCED ASTHMA IN ELITE ATHLETES. (PHD) 2004.

Supervisors:

O''Hehir, R (Main), Douglass ((Double Id)), J (Associate).

Student:

Papalia, L.

Program of Study:

CHARACTERISATION AND MODULATION OF THE T CELL RESPONSE TO RYE GRASS POLLEN ALLERGENS. (Masters) 2001.

Supervisors:

Rolland, J (Main), O''Hehir, R (Joint-Co).

Student:

Sutherland, M.

Program of Study:

THE HUMAN IMMUNE RESPONSE TO THE LATEX ALLERGEN HEV B 5. (PHD) 2003.

Supervisors:

O''Hehir, R (Main), Rolland, J (Associate), Suphioglu, C (Associate).