Assoc Prof Mark Wright - Researcher Profile

Mark Wright

Address

Department of Immunology
Monash University, The Alfred Hospital

Contact Details

Tel: +61 3 990 30703

Email: Mark.Wright@monash.edu


Biography

Mark works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as an Associate Professor.

Qualifications

DOCTOR OF PHILOSOPHY
Institution: University of Melbourne
Year awarded: 1990
Unknown
Institution: University of Melbourne
Year awarded: 1984

Publications

Journal Articles

Zhang, J., Czabotar, P.E., Policheni, A.N., Caminschi, I., Wan, S., Kitsoulis, S., Tullett, K.M., Robin, A.Y., Brammananth, R., van Delft, M.F., Lu, J., O'Reilly, L.A., Josefsson, E.C., Kile, B.T., Chin, W., Mintern, J.D., Olshina, M.A., Wong, W., Baum, J., Wright, M.D., Huang, D.C., Mohandas, N., Coppel, R.L., Colman, P.M., Nicola, N.A., Shortman, K., Lahoud, M.H., 2012, The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments, Immunity [P], vol 36, issue 4, Cell Press, USA, pp. 646-657.

Jones, E., Demaria, M., Wright, M., 2011, Tetraspanins in cellular immunity, Biochemical Society Transactions [P], vol 39, issue 2, Portland Press Ltd, UK, pp. 506-511.

Orlowski, E., Chand, R., Yip, J., Wong, C., Goschnick, M.W., Wright, M.D., Ashman, L.K., Jackson, D.E., 2009, A platelet tetraspanin superfamily member, CD151, is required for regulation of thrombus growth and stability in vivo., Journal Of Thrombosis And Haemostasis [P], vol 7, issue 12, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 2074-2084.

Sheng, K., van Spriel, A.B., Gartlan, K., Sofi, M., Apostolopoulos, V., Ashman, L.K., Wright, M.D., 2009, Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC, European Journal Of Immunology [P], vol 39, issue 1, Wiley - VCH Verlag GmbH & Co. KGaA, Germany, pp. 50-55.

Lahoud, M., Proietto, A.I., Ahmet, F., Kitsoulis, S., Eidsmo, L., Wu, L., Sathe, P., Pietersz, S., Chang, H., Walker, I., Maraskovsky, E., Braley, H., Lew, A.M., Wright, M.D., Heath, W.R., Shortman, K., Caminschi, I., 2009, The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses, Journal Of Immunology [P], vol 182, issue 12, American Association of Immunologists, United States, pp. 7587-7594.

van Spriel, A., Sofi, M., Gartlan, K., van der Schaaf, A., Verschueren, I., Torensma, R., Raymakers, R.A.P., Loveland, B.E., Netea, M.G., Adema, G.J., Wright, M.D., Figdor, C.G., 2009, The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity, Plos Pathogens [P], vol 5, issue 3 (e1000338), Public Library of Science, United States, pp. 1-11.

Sheng, K., Kalkanidis, M., Pouniotis, D., Wright, M.D., Pietersz, G.A., Apostolopoulos, V., 2008, The adjuvanticity of a mannosylated antigen reveals TLR4 functionality essential for subset specialization and functional maturation of mouse dendritic cells, Journal of Immunology, vol 181, issue 4, American Association of Immunologists, United States, pp. 2455-2464.

Caminschi, I., Proietto, A.I., Ahmet, F., Kitsoulis, S., Teh, J., Lo, J.Y., Rizzitelli, A., Wu, L., Vremec, D., van Dommelen, S.L., Campbell, I.K., Maraskovsky, E., Braley, H., Davey, G.M., Mottram, P.L., van de Velde, N.C., Jensen, K., Lew, A.M., Wright, M.D., Heath, W.R., Shortman, K., Lahoud, M.H., 2008, The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement, Blood [P], vol 112, issue 8, American Society of Hematology, USA, pp. 3264-3273.

Meyer-Wentrup, F., Figdor, C.G., Ansems, M., Brossart, P., Wright, M.D., Adema, G.J., van Spriel, A., 2007, Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production, Journal Of Immunology [P], vol 178, issue 1, American Association of Immunologists, United States, pp. 154-162.

Caminschi, I., Corbett, A., Zahra, C., Lahoud, M., Lucas, K., Sofi, M., Vremec, D., Gramberg, T., Pohlmann, S., Curtis, J., Handman, E., van Dommelen, S.L., Fleming, P., Degli-Esposti, M., Shortman, K., Wright, M.D., 2006, Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN, International Immunology [P], vol 18, issue 5, Oxford University Press, United Kingdom, pp. 741-753.

Caminschi, I., Vandenabeele, S., Sofi, M., McKnight, A.J., Ward, N., Brodnicki, T.C., Toy, T., Lahoud, M., Maraskovsky, E., Shortman, K., Wright, M.D., 2006, Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE, Dna Sequence [P], vol 17, issue 1, Informa Healthcare, United Kingdom, pp. 8-14.

Sheng, K., Pouniotis, D., Wright, M.D., Tang, C.K., Lazoura, E., Pietersz, G.A., Apostolopoulos, V., 2006, Mannan derivatives induce phenotypic and functional maturation of mouse dendritic cells, Immunology [P], vol 118, issue 3, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 372-383.

Lahoud, M.H., Proietto, A.I., Gartlan, K., Kitsoulis, S., Curtis, J., Wettenhall, J., Sofi, M., Daunt, C.P., O'Keeffe, M., Caminschi, I., Satterley, K., Rizzitelli, A., Schnorrer, P., Hinohara, A., Yamaguchi, Y., Wu, L., Smyth, G.K., Handman, E., Shortman, K., Wright, M.D., 2006, Signal regulatory protein molecules are differentially expressed, by CD8- dendritic cells, Journal Of Immunology [P], vol 177, issue 1, American Association of Immunologists, United States, pp. 372-382.

Cowin, A.J., Adams, D., Geary, S., Wright, M.D., Jones, J.C., Ashman, L.K., 2006, Wound healing is defective in mice lacking tetraspanin CD151, Journal of Investigative Dermatology [P], vol 126, issue 3, Nature Publishing Group, United Kingdom, pp. 680-689.

Van den Berg, T.K., van Beek, E.M., Buhring, H., Colonna, M., Hamaguhi, M., Howard, C.J., Kasuga, M., Liu, Y., Matozaki, T., Neel, B., Parkos, C.A., Sano, S., Vignery, A., Vivier, E., Wright, M.D., Zawatzky, R., Barclay, A., 2005, A nomenclature for signal regulatory protein family members, Journal Of Immunology [P], vol 175, issue 12, American Association of Immunologists, USA, pp. 7788-7789.

Corbett, A., Caminschi, I., McKenzie, B., Brady, J.L., Wright, M.D., Mottram, P.L., Hogarth, P.M., Hodder, A.N., Zhan, Y., Tarlinton, D.M., Shortman, K., Lew, A.M., 2005, Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger", European Journal Of Immunology [P], vol 35, issue 10, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 2815-2825.

Sheng, K., Pietersz, G.A., Wright, M.D., Apostolopoulos, V., 2005, Dendritic cells: Activation and maturation - Applications for cancer immunotherapy, Current Medicinal Chemistry [P], vol 12, issue 15, Bentham Science Publishers Ltd, Netherlands, pp. 1783-1800.

Rizzitelli, A., Vremec, D., Villadangos, J.A., Mavaddat, N., Wright, M.D., Shortman, K., 2005, Switching from a restricted to an effective CD4 T cell response by activating CD8+ murine dendritic cells with a Toll-like receptor 9 ligand, European Journal Of Immunology [P], vol 35, issue 11, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 3209-3220.

van Spriel, A.B., Puls, K.L., Sofi, M., Pouniotis, D., Hochrein, H., Orinska, Z., Knobeloch, K., Plebanski, M., Wright, M.D., 2004, A regulatory role for CD37 in T cell proliferation, Journal Of Immunology [P], vol 172, issue 5, American Association of Immunologists, United States, pp. 2953-2961.

Proietto, A.I., O'Keeffe, M., Gartlan, K., Wright, M.D., Shortman, K., Wu, L., Lahoud, M., 2004, Differential production of inflammatory chemokines by murine dendritic cell subsets, Immunobiology [P], vol 209, issue 1-2, Urban und Fischer Verlag, Germany, pp. 163-172.

Tarrant, J.M., Robb, L., van Spriel, A.B., Wright, M.D., 2003, Tetraspanins: Molecular organisers of the leukocyte surface, Trends In Immunology [P], vol 24, issue 11, Elsevier Ltd., Trends Journals, United Kingdom, pp. 610-617.

Postgraduate Research Supervisions

Current Supervision

Program of Study:
(DOCTORATE BY RESEARCH).
Thesis Title:
A reverse genetics approach to tetraspanin CD82.
Supervisors:
Wright, M (Main).
Program of Study:
(DOCTORATE BY RESEARCH).
Thesis Title:
The function of leucocyte-specific tetraspanins CD37 and CD53 in the immune system..
Supervisors:
Wright, M (Main).
Program of Study:
(DOCTORATE BY RESEARCH).
Thesis Title:
Towards developing cytokines as therapeutics for infections in pigs.
Supervisors:
Wright, M (Main).
Program of Study:
(DOCTORATE BY RESEARCH).
Thesis Title:
Where is all begins - exploring dendritic cell control of virtal infection and cell development in the bone marrow of mice and man.
Supervisors:
O''Keeffe, M (Main), Wright, M (Associate).