Assoc Prof Andrea Robinson - Researcher Profile

Biography

Andrea works in the School of Chemistry at Monash University as a Associate Professor

Andrea’s research areas of interest are:

Chemical Biology
• Cyclic peptides
• Disulfide replacement
• ALTMET polymerisation

Catalysis
• Spirocycles
• Renewables chemistry
• Fungal pigments

 

Keywords

Chemical Biology, Catalysis

Qualifications

DOCTOR OF PHILOSOPHY

Institution: Monash University

Year awarded: 1997

BACH OF SCIENCE

Institution: Monash University

Year awarded: 1989

Publications

Journal Articles

Van Der Werff, L., Robinson, A.J., Kyratzis, I.L., 2012, Combinatorial approach for the rapid determination of thermochromic behavior of binary and ternary cholesteric liquid crystalline mixtures, Journal of Combinatorial Chemistry [E], vol 14, issue 11, American Chemical Society, United States, pp. 605-612.

Byrnes, M.J., Hilton, A.M., Woodward, C.P., Jackson, W.R., Robinson, A.J., 2012, Electrostatic immobilization of an olefin metathesis pre-catalyst on iron oxide magnetic particles, Green Chemistry [P], vol 14, issue 1, Royal Society of Chemistry Publications, United Kingdom, pp. 81-84.

Woodward, C.P., Spiccia, N.D., Jackson, W.R., Robinson, A.J., 2011, A simple amine protection strategy for olefin metathesis reactions, Chemical Communications [P], vol 47, issue 2, Royal Society of Chemistry, UK, pp. 779-781.

Van Lierop, B., Bornschein, C., Jackson, W., Robinson, A., 2011, Ring-closing metathesis in peptides - the sting is in the tail!, Australian Journal of Chemistry [E], vol 64, issue 6, CSIRO Publishing, Collingwood Vic Australia, pp. 806-811.

Young, J., Thienthong, N., Hearn, M., Robinson, A., Jackson, W., 2011, Synthesis and evaluation of potentially transdermal morphine derivatives, Australian Journal of Chemistry [E], vol 64, issue 10, CSIRO Publishing, Collingwood Vic Australia, pp. 1339-1345.

Mountford, S., Campi, E., Robinson, A., Hearn, M., 2011, Synthesis of N-heterocyclic ligands for use in affinity and mixed mode chromatography, Tetrahedron [P], vol 67, issue 2, Pergamon Elsevier Science Ltd, Oxford England, pp. 471-485.

Hossain, M., Guilhaudis, L., Sonnevend, A., Attoub, S., Van Lierop, B., Robinson, A., Wade, J., Conlon, J., 2011, Synthesis, conformational analysis and biological properties of a dicarba derivative of the antimicrobial peptide, brevinin-1BYa, European Biophysics Journal With Biophysics Letters [P], vol 40, issue 4, Springer, New York USA, pp. 555-564.

Van Lierop, B.J., Jackson, W.R., Robinson, A.J., 2010, 5,5-Dimethylproline dipeptides: Anacid-stable class of pseudoproline, Tetrahedron [P], vol 66, issue 29, Pergamon Elsevier Science Ltd, Oxford England, pp. 5357-5366.

Van Lierop, B., Whelan, A., Andrikopoulos, S., Mulder, R., Jackson, W., Robinson, A., 2010, Methods for enhancing ring closing metathesis yield in peptides: synthesis of a dicarba human growth hormone fragment, International Journal Of Peptide Research And Therapeutics [P], vol 16, issue 3, Springer, New York USA, pp. 133-144.

Zhang, s., Hughes, R., Bathgate, R., Shabanpoor, F., Hossain, M., Lin, F., Van Lierop, B., Robinson, A., Wade, J., 2010, Role of the intra-A-chain disulfide bond of insulin-like peptide 3 in binding and activation of its receptor, RXFP2, Peptides [P], vol 31, issue 9, Elsevier Science Inc, New York USA, pp. 1730-1736.

Mountford, S.J., Campi, E.M., Robinson, A.J., Hearn, M.T.W., 2010, S -> N type Smiles rearrangement of the aminoethanethiol moiety attached to heterocyclic compounds, Tetrahedron [P], vol 66, issue 19, Pergamon Elsevier Science LTD, Oxford England, pp. 3452-3456.

Illesinghe, J.P.M., Guo, C., Garland, R., Ahmed, A., Van Lierop, B.J., Elaridi, J., Jackson, W.R., Robinson, A.J., 2009, Metathesis assisted synthesis of cyclic peptides, Chemical Communications [P], Royal Society of Chemistry, United Kingdom, pp. 295-297.

Robinson, A.J., Van Lierop, B.J., Garland, R., Teoh, C.M.E., Elaridi, J., Illesinghe, J.P.M., Jackson, W.R., 2009, Regioselective formation of interlocked dicarba bridges in naturally occurring cyclic peptide toxins using olefin metathesis, Chemical Communications [P], Royal Society of Chemistry, UK, pp. 4293-4295.

Hossain, M.A., Rosengren, K.J., Zhang, S., Bathgate, R.A.D., Tregear, G.W., Van Lierop, B.J., Robinson, A.J., Wade, J.D., 2009, Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity, Organic & Biomolecular Chemistry [P], vol 7, issue 8, Royal Society of Chemistry, United Kingdom, pp. 1547-1553.

MacRaild, C.A., Illesinghe, J., Van Lierop, B.J., Townsend, A.L., Chebib, M., Livett, B.G., Robinson, A.J., Norton, R.S., 2009, Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an a-conotoxin containing a nonreducible cystine analogue, Journal of Medicinal Chemistry [P], vol 52, issue 3, American Chemical Society, United States, pp. 755-762.

Robinson, A.J., Elaridi, J., Van Lierop, B.J., Mujcinovic, S., Jackson, W.R., 2007, Microwave-assisted RCM for the synthesis of carbocyclic peptides, Journal of Peptide Science, vol 13, issue 4, John Wiley & Sons Ltd., UK, pp. 280-285.

Elaridi, J., Patel, J., Jackson, W.R., Robinson, A.J., 2006, Controlled synthesis of (S,S)-2,7-diaminosuberic acid: A method for regioselective construction of dicarba analogues of multicystine-containing peptides, Journal of Organic Chemistry, vol 71, issue 20, American Chemical Society, USA, pp. 7538-7545.

Patel, J., Mujcinovic, S., Jackson, W.R., Robinson, A.J., Serelis, A.K., Such, C.H., 2006, High conversion and productive catalyst turnovers in cross-metathesis reactions of natural oils with 2-butene, Green Chemistry, vol 8, issue 5, Royal Society of Chemistry, UK, pp. 450-454.

Zhu, Y., Patel, J., Mujcinovic, S., Jackson, W.R., Robinson, A.J., 2006, Preparation of terminal oxygenates from renewable natural oils by a one-pot metathesis-isomerisation-methoxycarbonylation-transesterification reaction sequence, Green Chemistry, vol 8, issue 8, Royal Society of Chemistry, UK, pp. 746-749.

Elaridi, J., Jackson, W.R., Robinson, A.J., 2005, A catalytic asymmetric synthesis of 5,5-dimethylproline, Tetrahedron: Asymmetry, vol 16, issue 11, Pergamon Elsevier Science LTD, Oxford England, pp. 2025-2029.

Robinson, A.J., Elaridi, J., Patel, J., Jackson, W.R., 2005, A one pot, metathesis-hydrogenation sequence for the selective formation of carbon-carbon bonds, Chemical Communications, issue 44, The Royal Society of Chemistry, Cambridge England, pp. 5544-5545.

Elaridi, J., Thaqi, A., Prosser, A., Jackson, W.R., Robinson, A.J., 2005, An enantioselective synthesis of beta2-animo acid derivatives, Tetahedron Asymmetry, vol 16, issue 7, Pergamon-Elsevier Science Ltd, Oxford England, pp. 1309-1319.

Patel, J., Elaridi, J., Jackson, W.R., Robinson, A.J., Serelis, A.K., Such, C.H., 2005, Cross-metathesis of unsaturated natural oils with 2-butene. High conversion and productive catalyst turnovers, Chemical Communications, issue 44, Royal Society of Chemistry, Cambridge England, pp. 5546-5547.

Teoh, C.M.E., Jackson, W.R., Robinson, A.J., 2005, Cyclic alpha-amino acids via enantioselective metal-catalyzed cascade reactions of dienamides in supercritical carbon dioxide, Australian Journal of Chemistry, vol 58, issue 1, CSIRO Publishing, Collingwood Vic Australia, pp. 63-65.

Whelan, A.N., Elaridi, J., Mulder, R.J., Robinson, A.J., Jackson, W.R., 2005, Metal-catalysed tandem metathesis-hydrogenation reactions for the synthesis of carba analogues of cyclic peptides, Canadian Journal of Chemistry, vol 83, issue 6-7, National Research of Council of Canada, Ottawa Canada, pp. 875-881.

Whelan, A.N., Elaridi, J., Harte, M.F., Smith, S.V., Jackson, W.R., Robinson, A.J., 2004, A tandem metathesis-hydrogenation route to dicarba analogues of cystine-containing cyclic peptides, Tetrahedron Letters, vol 45, issue 52, Elsevier, Oxford England, pp. 9545-9547.

Illesinghe, J.P.M., Ebeling, R., Ferguson, B., Patel, J., Campi, E.M., Jackson, W.R., Robinson, A.J., 2004, An evaluation of some hindered diamines as chiral modifiers of metal-promoted reactions, Australian Journal of Chemistry, vol 57, CSIRO Publishing, Collingwood Vic Australia, pp. 167-176.

Illesinghe, J.P.M., Campi, E.M., Jackson, W.R., Robinson, A.J., 2004, Synthesis of nitrogen heterocycles by rhodium-catalyzed hydroformylation of polymer-attached amino alkenes with syngas, Australian Journal of Chemistry, vol 57, issue 6, CSIRO Publishing, Australia, pp. 531-536.

Fallon, G.D., Illesinghe, J.P.M., Campi, E.M., Jackson, W.R., Robinson, A.J., 2003, 1,2-Bis[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]benzene, Acta Crystallographica Section E: Structure Reports Online [P], vol E59, issue 8, Wiley-Blackwell Munksgaard, Denmark, United States, Netherlands, United Kingdom, pp. 01163-01164.

Joubran, L., Jackson, W.R., Campi, E.M., Robinson, A.J., Wells, B.A., Godfrey, P.D., Callaway, J.K., Jarrott, B., 2003, Arylpropanolamines incorporating an antioxidant function as neuroprotective agents, Australian Journal of Chemistry, vol 56, issue 6, CSIRO Publishing, Collingwood Vic Australia, pp. 597-605.

Teoh, C.M., Campi, E.M., Jackson, W.R., Robinson, A.J., 2003, One-pot tandem enantioselective hydrogenation-hydroformylation synthesis of cyclic alpha-amino acids, New Journal of Chemistry, vol 27, issue 2, Royal Society of Chemistry, Cambridge England, pp. 387-394.

Robinson, A.J., DeLucca, I., Drummond, S., Boswell, G.A., 2003, Steroidal nitrone inhibitors of 5-reductase, Tetrahedron Letters, vol 44, Pergamon-Elsevier Science Ltd, Oxford England, pp. 4801-4804.

Aguilar, M., Fallon, G.D., Mayes, P.A., Nordin, S., Robinson, A.J., Rose, M.L., Vounatsos, F., Wilman, B.E., Perlmutter, P., 2003, The asymmetric imino-aldol approach to the enantioselective synthesis of beta-amino acids, Letters in Peptide Science, vol 10, issue 5-6, Kluwer Academic Publishers, Dordrecht The Netherlands, pp. 597-604.

Teoh, C.M., Campi, E.M., Jackson, W.R., Robinson, A.J., 2002, A highly enantioselective synthesis of cyclic -amino acids involving a one-pot, single catalyst, tandem hydrogenation-hydroformylation sequence, Chemical Communications, vol 9, Royal Society of Chemistry, Cambridge England, pp. 978-979.

Saylik, D., Campi, E.M., Donohue, A.C., Jackson, W.R., Robinson, A.J., 2001, A new enantioselective synthesis of b-amino acids, Tetrahedron: Asymmetry, vol 12, issue 4, Pergamon-Elsevier Science Ltd, Oxford England, pp. 657-667.

Robinson, A.J., Stanislawski, P., Mulholland, D., He, L., Li, H., 2001, Expedient asymmetric synthesis of all four isomers of N,N-protected 2,3-diaminobutanoic Acid, Journal of Organic Chemistry, vol 66, American Chemical society, Washington USA, pp. 4148-4152.

Robinson, A.J., Lim, C., He, L., Ma, P., Li, H., 2001, Highly enantioselective synthesis of a,b-diaminopropanoic acid derivatives using a catalytic asymmetric hydrogenation approach, Journal of Organic Chemistry, vol 66, issue 12, American Chemical Society, Washington USA, pp. 4141-4147.

Robinson, A.J., 1997, Catalytic asymmetric hydrogenation; new chiral ligands for asymmetric synthesis; rearrangement chemistry of 4-hydroxy-4,5-dihydroazepines, Chemistry in Australia, vol december, RACI, Australia, pp. 40-41.

Duggan, P.J., Robinson, A.J., White, P.A., 1997, Extracts, Theoretical Work, vol no, Chemistry in Australia, Australia, p. 44.

Robinson, A.J., 1997, The Honours Year, Chemistry in Australia, vol november, RACI, Australia, p. 48.

Kerr, J.S., Li, H., Wexler, R.S., Robinson, A.J., Robinson, C.S., Boswell, G.A., Krauthauser, C., Harlow, P.P., 1997, The characterization of potent novel warfarin analogs, Thrombosis Research, vol 88, Elsevier, USA, pp. 127-136.

Zhang, Z., Kerr, J.S., Wexler, R.S., Li, H., Robinson, A.J., Harlow, P.P., Kaminsky, L.S., 1997, Warfarin analog inhibition of human CYP2C9-catalyzed S-warfarin 7-hydroxylation, Thrombosis Research, vol 88, Elsevier, USA, pp. 389-398.

Other

Robinson, A., Elaridi, J., 2010, Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides, USA.

Robinson, A., Jackson, W., Patel, J., Elaridi, J., 2009, Methods for the synthesis of two or more dicarba bridges in organic compounds, USA.

Jackson, W., Robinson, A., Serelis, A., Patel, J., Such, C., 2007, Crosslinking method, Australia.

Aulsebrook, K., Smith, P., Williams, N.H., Robinson, A., 1997, Chemistry in the home, The Sunday Age, The Age, Melbourne Vic Australia.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Catalytic and tandem catalytic routes to small organic molecules.

Supervisors:

Robinson, A (Main).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Functionalistion of N-Heterocyclic carbene and hoveyda ligands for application in olefin metathesis..

Supervisors:

Robinson, A (Main), Jackson, W (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Natural Product Synthesis.

Supervisors:

Tuck, K (Main), Robinson, A (Associate).

Completed Supervision

Student:

Chau, B.

Program of Study:

Dual acting antioxidant hybrids. (PHD) 2011.

Supervisors:

Jackson, W (Joint-Co), Robinson, A (Joint).

Student:

Elaridi, J.

Program of Study:

Meta-catalysed routes to peptidomimetics. (PHD) 2005.

Supervisors:

Robinson, A (Main), Jackson, W (Associate).

Student:

Illesinghe, J.

Program of Study:

SYNTHESIS AND USE OF NITROGEN HETEROCYCLES IN METAL MEDIATED REACTIONS. (PHD) 2004.

Supervisors:

Robinson, A (Main).

Student:

Kurniaty, N.

Program of Study:

Synthesis of Peptidomimetics using Olefin Metathesis. (Masters) 2012.

Supervisors:

Robinson, A (Main).

Student:

Lim, C.

Program of Study:

A CATALYTIC ASYMMETRIC HYDROGENATION APPROACH TOWARDS THE SYNTHESIS OF BETA-LACTAM ANTIBIOTICS. (PHD) 2002.

Supervisors:

Robinson, A (Main), Dickson, R (Associate).

Student:

Mountford, S.

Program of Study:

Preparation of novel ligands for antibody purification. (PHD) 2006.

Supervisors:

Hearn, M (Joint-Co), Robinson, A (Joint).

Student:

Suraweera, P.

Program of Study:

Investigation of the intramolecular aza-ene reaction for the construction of aromatic and heterocyclic compunds & synthesis of B-amino acid derivatives via catalytic asymmetric hydrogenation. (Masters) 2003.

Supervisors:

Robinson, A (Main).

Student:

Teoh, C.

Program of Study:

SYNTHESIS OF AMINO ACIDS BY METAL-CATALYSED REACTIONS. (PHD) 2004.

Supervisors:

Robinson, A (Main).

Student:

Van Der Werff, L.

Program of Study:

Thermochromic composite fibres for thermal mapping in the physiological temperature range. (PHD) 2012.

Supervisors:

Robinson, A (Main).

Student:

Van Lierop, B.

Program of Study:

Dicarba mimetics of cystine-containing peptides. (PHD) 2010.

Supervisors:

Robinson, A (Main).

Student:

Welgama, C.

Program of Study:

A catalytic approach to peptide-polymer hybrids. (PHD) 2011.

Supervisors:

Robinson, A (Main), Elaridi, J (Associate).

Student:

Whelan, A.

Program of Study:

Synthesis of novel peptidomimetics via olefin metathesis. (PHD) 2009.

Supervisors:

Robinson, A (Main).