Ms Emma Van Der Westhuizen - Researcher Profile

Biography

Position 
Research Fellow
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences

Qualifications

PHD IN PHARMACOLOGY

Institution: Monash University

Year awarded: 2009

BACHELOR OF SCIENCE (HONORS IN PHARMACOLOGY)

Institution: University of Melbourne

Year awarded: 2000

Publications

Journal Articles

Bathgate, R., Halls, M.L., Van Der Westhuizen, E.T., Callander, G., Kocan, M., Summers, R.J., 2013, Relaxin family peptides and their receptors, Physiological Reviews [P], vol 93, issue 1, The American Physiological Society, Bethesda Maryland USA, pp. 405-480.

Van Der Westhuizen, E., Christopoulos, A., Sexton, P., Wade, J., Summers, R., 2010, H2 relaxin is a biased ligand relative to H3 relaxin at the relaxin family peptide receptor 3 (RXFP3) [S], Molecular Pharmacology [P], vol 77, issue 5, American Society for Pharmacology and Experimental Therapeutics, United States, pp. 759-772.

van der Westhuizen, E.T., Wade, J.D., Sexton, P.M., Summers, R.J., 2009, Addition of a carboxy-terminal green fluorescent protein does not alter the binding and signaling properties of relaxin family peptide receptor 3, Annals of the New York Academy of Sciences [P], vol 1160, Wiley-Blackwell Publishing, Inc., USA, pp. 105-107.

Halls, M.L., van der Westhuizen, E.T., Wade, J.D., Evans, B.A., Bathgate, R.A.D., Summers, R.J., 2009, Relaxin family peptide receptor (RXFP1) coupling to Galphai3, involves the C-terminal Arg752 and localization within membrane raft microdomains, Molecular Pharmacology [P], vol 75, issue 2, American Society for Pharmacology and Experimental Therapeutics, USA, pp. 415-428.

Summers, R.J., Bathgate, R.A.D., Wade, J.D., van der Westhuizen, E.T., Halls, M.L., 2009, Roles of the receptor, the ligand, and the cell in the signal transduction pathways utilized by the relaxin family peptide receptors 1-3, Annals of the New York Academy of Sciences [P], vol 1160, Wiley-Blackwell Publishing, Inc., USA, pp. 99-104.

Van Der Westhuizen, E.T., Halls, M.L., Samuel, C.S., Bathgate, R., Unemori, E.N., Sutton, S.W., Summers, R.J., 2008, Relaxin family peptide receptors - from orphans to therapeutic targets, Drug Discovery Today, vol 13, issue 15-16, Elsevier Ltd., United Kingdom, pp. 640-651.

Halls, M.L., Van Der Westhuizen, E.T., Bathgate, R., Summers, R.J., 2007, Relaxin family peptide receptors - Former orphans reunite with their parent ligands to activate multiple signalling pathways, British Journal of Pharmacology, vol 150, issue 6, Nature Publishing Group, London England UK, pp. 677-691.

Van Der Westhuizen, E.T., Summers, R.J., Halls, M.L., Bathgate, R., Sexton, P., 2007, Relaxin receptors - new drug targets for multiple disease states, Current Drug Targets, vol 8, issue 1, Bentham Science Ltd, Sharjah UAE, pp. 91-104.

Van Der Westhuizen, E.T., Werry, T.D., Sexton, P., Summers, R.J., 2007, The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependent mechanism, Molecular Pharmacology, vol 71, issue 6, American Society of Pharmacology, Experimental Therapeutics, Bethesda MD USA, pp. 1618-1629.

Chu, S., Rushdi, S., Zumpe, E.T., Mamers, P., Healy, D.W., Jobling, T., Burger, H., Fuller, P.J., 2002, FSH-regulated gene expression profiles in ovarian tumours and normal ovaries, Molecular Human Reproduction, vol 8, issue 5, Oxford University Press, Oxford UK, pp. 426-433.

Fuller, P.J., Zumpe, E.T., Chu, S., Mamers, P., Burger, H., 2002, Inhibin-Activin Receptor Subunit Gene Expression in Ovarian Tumors, The Journal of Clinical Endocrinology and Metabolism, vol 87, The Endocrine Society, USA, pp. 1395-1401.

Conference Proceedings

Van Der Westhuizen, E.T., Sexton, P.M., Bathgate, R.A.D., Summers, R.J., 2005, Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry, Relaxin and Related Peptides: Fourth International Conference, 5 September 2004 to 10 September 2004, New York Academy of Sciences, New York USA, pp. 332-337.