Dr Vi Pham - Researcher Profile

Biography

Vi works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: University of Melbourne

Year awarded: 2005

Publications

Journal Articles

Pham, V., Albiston, A., Downes, C., Wong, C., Diwakarla, L.P., Ng, L., Lee, S., Crack, P., Chai, S., 2012, Insulin-regulated aminopeptidase deficiency provides protection against ischemic stroke in mice, Journal of Neurotrauma [P], vol 29, issue 6, Mary Ann Liebert, Inc. Publishers, USA, pp. 1243-1248.

Albiston, A.L., Yeatman, H.R., Pham, V., Fuller, S.J., Diwakarla, S., Fernando, R.N., Chai, S.Y., 2011, Distinct distribution of GLUT4 and insulin regulated aminopeptidase in the mouse kidney, Regulatory Peptides [P], vol 166, issue 1-3, Elsevier BV, The Netherlands, pp. 83-89.

Albiston, A., Diwakarla, S., Fernando, R., Mountford, S., Yeatman, H., Morgan, B., Pham, V., Holien, J., Parker, M., Thompson, P., Chai, S., 2011, Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers, British Journal of Pharmacology [P], vol 164, issue 1, John Wiley & Sons Ltd, UK, pp. 37-47.

Albiston, A.L., Fernando, R.N., Yeatman, H.R., Burns, P., Ng, L., Daswani, D., Diwakarla, S., Pham, V., Chai, S.Y., 2010, Gene knockout of insulin-regulated aminopeptidase: Loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory, Neurobiology Of Learning And Memory [P], vol 93, issue 1, Academic Press, USA, pp. 19-30.

Albiston, A., Pham, V., Ye, S., Ng, L., Lew, R., Thompson, P., Butler, J., Morton, C., Parker, M., Chai, S., 2010, Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase, Molecular Pharmacology [P], vol 78, issue 4, The American Society for Pharmacology and Experimental Therapeutics, Bethesda Maryland USA, pp. 600-607.

Kim, J., Castellano, J.M., Jiang, H., Basak, J.M., Parsadanian, M., Pham, V., Mason, S.M., Paul, S.M., Holtzman, D.M., 2009, Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular Abeta clearance, Neuron [P], vol 64, issue 5, Cell Press, USA, pp. 632-644.

Pham, V., Burns, P., Albiston, A.L., Yeatman, H.R., Ng, L., Diwakarla, L.P., Chai, S.Y., 2009, Reproduction and maternal behavior in insulin-regulated aminopeptidase (IRAP) knockout mice, Peptides [P], vol 30, issue 10, Elsevier Inc., USA, pp. 1861-1865.

Albiston, A.L., Morton, C.J., Ng, H.L., Pham, V., Yeatman, H.R., Ye, S., Fernando, R.N., De Bundel, D., Ascher, D.B., Mendelsohn, F.A., Parker, M.W., Chai, S.Y., 2008, Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase, Faseb Journal [P], vol 22, issue 12, Federation of American Societies for Experimental Biology, USA, pp. 4209-4217.

Peck, G.R., Ye, S., Pham, V., Fernando, N.R., Macaulay, S.L., Chai, S.Y., Albiston, A.L., 2006, Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase, Molecular Endocrinology [P], vol 20, issue 10, The Endocrine Society, USA, pp. 2576-2583.

Pham, V., Dong, M., Wade, J.D., Miller, L.J., Morton, C.J., Ng, H., Parker, M.W., Sexton, P.M., 2005, Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling, Journal of Biological Chemistry, vol 280, issue 31, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 28610-28622.

Pham, V., Wade, J.D., Purdue, B.W., Sexton, P.M., 2004, Spatial proximity between a photolabile residue in position 19 of salmon calcitonin and the amino terminus of the human calcitonin receptor, Journal of Biological Chemistry, vol 279, issue 8, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 6720-6729.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Inhibition of an Aminopeptidase: A Novel Therapeutic Stratergy For Stroke.

Supervisors:

Chai, S (Main), Pham, V (Associate).