Prof Gary Egan - Researcher Profile

Biography

Brain maps reveal disease pathways

There is no cure for genetically inherited conditions, such as Huntington’s disease, that cause the brain to degenerate. Neuroscientist Professor Gary Egan is working to change that. He is leading research to map the progress of these diseases using ultra-powerful imaging equipment, with the aim of developing treatments to slow or prevent the onset of brain degeneration.

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Keywords

Commentary: biomedical imaging and neuroimaging, Supervision: neuroscience, imaging sciences

Qualifications

MASTER OF BUSINESS ADMINISTRATION (MBA)

Institution: Monash University

Year awarded: 1999

DOCTORATE OF PHILOSOPHY (PHD)

Institution: University of Melbourne

Year awarded: 1990

BACHELOR OF SCIENCE (HONOURS)

Institution: University of Melbourne

Year awarded: 1983

Publications

Journal Articles

Akhlaghi, H., Corben, L.A., Georgiou-Karistianis, N., Bradshaw, J.L., Delatycki, M., Storey, E., Egan, G.F., 2012, A functional MRI study of motor dysfunction in Friedreich's ataxia, Brain Research [P], vol 1471, Elsevier, Netherlands, pp. 138-154.

Georgiou-Karistianis, N., Akhlaghi, H., Corben, L.A., Delatycki, M., Storey, E., Bradshaw, J.L., Egan, G.F., 2012, Decreased functional brain activation in Friedreich ataxia using the Simon effect task, Brain And Cognition [P], vol 79, issue 3, Academic Press, United States, pp. 200-208.

Kolbe, S.C., Marriott, M., van der Walt, A., Fielding, J., Klistorner, A., Mitchell, P.J., Butzkueven, H., Kilpatrick, T.J., Egan, G.F., 2012, Diffusion tensor imaging correlates of visual impairment in multiple sclerosis and chronic optic neuritis, Investigative Ophthalmology and Visual Science [P], vol 53, issue 2, Association for Research in Vision and Ophthalmology, USA, pp. 825-832.

Kolbe, S.C., Bajraszewski, C., Chapman, C., Nguyen, T., Mitchell, P.J., Paine, M., Butzkueven, H., Johnston, L., Kilpatrick, T.J., Egan, G.F., 2012, Diffusion tensor imaging of the optic radiations after optic neuritis, Human Brain Mapping [P], vol 33, issue 9, John Wiley & Sons, Inc, USA, pp. 2047-2061.

Murawski, C., Harris, P.G., Bode, S., Dominguez, J.F., Egan, G.F., 2012, Led into temptation? rewarding brand logos bias the neural encoding of incidental economic decisions, PLoS ONE [P], vol 7, issue 3 (Art. No.: e34155), Public Library of Science, United States, pp. 1-12.

Gresle, M.M., Alexandrou, E., Wu, Q., Egan, G.F., Jokubaitis, V., Ayers, M., Jonas, A., Doherty, W., Friedhuber, A., Shaw, G., Sendtner, M., Emery, B., Kilpatrick, T., Butzkueven, H., 2012, Leukemia inhibitory factor protects axons in experimental autoimmune encephalomyelitis via an oligodendrocyte-independent mechanism, PLoS ONE [P], vol 7, issue 10 (Art. No.: e47379), Public Library of Science, United States, pp. 1-12.

Wang, Y., Van Der Walt, A., Paine, M., Klistorner, A., Butzkueven, H., Egan, G.F., Kilpatrick, T., Kolbe, S.C., 2012, Optic nerve magnetisation transfer ratio after acute optic neuritis predicts axonal and visual outcomes, PLoS ONE [P], vol 7, issue 12, Public Library of Science, San Francisco CA USA, pp. 1-7.

Ullmann, J.F., Keller, M.D., Watson, C., Janke, A.L., Kurniawan, N.D., Yang, Z., Richards, K., Paxinos, G., Egan, G.F., Petrou, S., Bartlett, P., Galloway, G.J., Reutens, D.C., 2012, Segmentation of the C57BL/6J mouse cerebellum in magnetic resonance images, Neuroimage [P], vol 62, issue 3, Elsevier BV, Netherlands, pp. 1408-1414.

Lei, P., Ayton, S., Finkelstein, D.I., Spoerri, L., Ciccotosto, G.D., Wright, D.K., Wong, B.X.W., Adlard, P.A., Cherny, R.A., Lam, L.Q., Roberts, B.R., Volitakis, I., Egan, G.F., McLean, C.A., Cappai, R., Duce, J.A., Bush, A.I., 2012, Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export, Nature Medicine [P], vol 18, issue 2, Nature Publishing Group, New York NY USA, pp. 291-295.

Stein, M.S., Liu, Y., Gray, O.M., Baker, J.E., Kolbe, S.C., Ditchfield, M.R., Egan, G.F., Mitchell, P.J., Harrison, L.C., Butzkueven, H., Kilpatrick, T.J., 2011, A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis, Neurology [P], vol 77, issue 17, Lippincott Williams & Wilkins, USA, pp. 1611-1618.

Thompson, D., Inder, T., Faggian, N., Johnston, L., Warfield, S., Anderson, P., Doyle, L., Egan, G., 2011, Characterization of the corpus callosum in very preterm and full-term infants using MRI, Neuroimage [P], vol 55, Academic Press, USA, pp. 479-490.

Bohanna, I., Georgiou-Karistianis, N., Egan, G., 2011, Connectivity-based segmentation of the striatum in Huntington's disease: Vulnerability of motor pathways, Neurobiology Of Disease [P], vol 42, issue 3, Academic Press, USA, pp. 475-481.

Bohanna, I., Georgiou-Karistianis, N., Sritharan, A., Asadi, H., Johnston, L., Churchyard, A., Egan, G., 2011, Diffusion tensor imaging in Huntington's disease reveals distinct patterns of white matter degeneration associated with motor and cognitive deficits, Brain Imaging and Behavior [P], vol 5, Springer New York LLC, United States, pp. 171-180.

Zalesky, A., Fornito, A., Seal, M., Cocchi, L., Westin, C., Bullmore, E., Egan, G.F., Pantelis, C., 2011, Disrupted axonal fiber connectivity in Schizophrenia, Biological Psychiatry [P], vol 69, Elsevier, USA, pp. 80-89.

Corben, L., Akhlaghi, H., Georgiou-Karistianis, N., Bradshaw, J., Egan, G., Storey, E., Churchyard, A., Delatycki, M., 2011, Impaired inhibition of prepotent motor tendencies in Friedreich ataxia demonstrated by the Simon interference task, Brain And Cognition [P], vol 76, issue 1, Academic Press, United States, pp. 140-145.

Mazzone, S., Egan, G., 2011, Investigation of the neural control of cough and cough suppression in humans using functional brain imaging, Journal Of Neuroscience [P], vol 31, issue 8, Society for Neuroscience, United States, pp. 2948-2958.

Mazzone, S., Cole, L., Ando, A., Egan, G., Farrell, M., 2011, Investigation of the neural control of cough and cough suppression in humans using functional brain imaging, Journal Of Neuroscience [P], vol 31, issue 8, Society for Neuroscience, United States, pp. 2948-2958.

Richards, K., Watson, C., Buckley, R., Kurniawan, N., Yang, Z., Keller, M., Beare, R., Bartlett, P., Egan, G., Galloway, G., Paxinos, G., Petrou, S., Reutens, D., 2011, Segmentation of the mouse hippocampal formation in magnetic resonance images, Neuroimage [P], vol 58, issue 3, Academic Press, United States, pp. 732-740.

Ng, A., Johnston, L., Chen, Z., Cho, Z., Zhang, J., Egan, G., 2011, Spatially dependent filtering for removing phase distortions at the cortical surface, Magnetic Resonance In Medicine [P], vol 66, issue 3, John Wiley & Sons Ltd, Massachusetts USA, pp. 784-793.

Davison, S., Bell, R., Gavrilescu, M., Searle, K., Maruff, P., Gogos, A., Rossell, S., Adams, J., Egan, G., Davis, S., 2011, Testosterone improves verbal learning and memory in postmenopausal women: Results from a pilot study, Maturitas [P], vol 70, issue 3, Elsevier Ireland Ltd, Ireland, pp. 307-311.

Cole, L., Gavrilescu, M., Johnston, L., Gibson, S., Farrell, M., Egan, G., 2011, The impact of Alzheimer's disease on the functional connectivity between brain regions underlying pain perception, European Journal of Pain [P], vol 15, Elsevier, UK, pp. 568e1-568e11.

Sritharan, A., Egan, G.F., Johnston, L.A., Horne, M.K., Bradshaw, J.L., Bohanna, I.K., Asadi, H., Cunnington, R., Churchyard, A.J., Chua, P., Farrow, M.A., Georgiou-Karistianis, N., 2010, A longitudinal diffusion tensor imaging study in symptomatic Huntington's disease, Journal Of Neurology Neurosurgery And Psychiatry [P], vol 81, BMJ Group, UK, pp. 257-262.

Cole, L., Farrell, M., Gibson, S., Egan, G., 2010, Age-related differences in pain sensitivity and regional brain activity evoked by noxious pressure, Neurobiology of Aging [P], vol 31, Elsevier, Springer New York LLC, pp. 494-503.

Chen, Z., Johnston, L., Kwon, D., Oh, S., Cho, Z., Egan, G., 2010, An optimised framework for reconstructing and processing MR phase images, Neuroimage [P], vol 49, Academic Press, USA, pp. 1289-1300.

Wilson, G.R., Wang, H.X., Egan, G.F., Robinson, P.J., Delatycki, M.B., O'Bryan, M.K., Lockhart, P.J., 2010, Deletion of the Parkin co-regulated gene causes defects in ependymal ciliary motility and hydrocephalus in the quakingviable mutant mouse, Human Molecular Genetics [P], vol 19, issue 8 (Art. No. ddq031), Oxford University Press, UK, pp. 1593-1602.

Georgiadis, J., Farrell, M., Boessen, R., Denton, D., Gavrilescu, M., Kortekaas, R., Renken, R., Hoogduin, J., Egan, G., 2010, Dynamic subcortical blood flow during male sexual activity with ecological validity: A perfusion fMRI study, Neuroimage [P], vol 50, Academic Press, United States, pp. 208-216.

Prescott, J., Gavrilescu, M., Cunnington, R., O'Boyle, M., Egan, G., 2010, Enhanced brain connectivity in math-gifted adolescents: An fMRI study using mental rotation, Cognitive Science [P], vol 1, Wiley, USA, pp. 277-288.

Gogos, A., Gavrilescu, M., Davison, S.L., Searle, K., Adams, J., Rossell, S.L., Bell, R.J., Davis, S.R., Egan, G.F., 2010, Greater superior than inferior parietal lobule activation with increasing rotation angle during mental rotation: An fMRI study, Neuropsychologia [P], vol 48, Pergamon, UK, pp. 529-535.

Chen, Z., Zhang, J., Yang, R., Kellman, P., Johnston, L., Egan, G., 2010, IIR GRAPPA for parallel MR image reconstruction, Magnetic Resonance In Medicine [P], vol 63, issue 2, John Wiley & Sons Inc., USA, pp. 502-509.

Cate, H., Wu, Q., Kemper, D., Merlo, D., Wang, H., Fang, K., Egan, G., Kilpatrick, T., 2010, Influence of methylprednisolone on magnetic resonance and histological measures during cuprizone-induced demyelination, Neuroscience Letters [P], vol 483, Elsevier Ireland, Ireland, pp. 47-52.

Van Der Walt, A., Butzkueven, H., Kolbe, S., Marriott, M., Alexandrou, E., Gresle, M., Egan, G., Kilpatrick, T., 2010, Neuroprotection in multiple sclerosis: A therapeutic challenge for the next decade, Pharmacology and Therapeutics [P], vol 126, Elsevier Inc., United States, pp. 82-93.

Gavrilescu, M., Rossell, S.L., Stuart, G.W., Shea, T., Innes-Brown, H., Henshall, K., McKay, C., Sergejew, A., Copolov, D.L., Egan, G.F., 2010, Reduced connectivity of the auditory cortex in patients with auditory hallucinations: A resting state functional magnetic resonance imaging study, Psychological Medicine [P], vol 40, Cambridge University Press, UK, pp. 1149-1158.

Matsuda, K., Wang, H., Suo, C., McCombe, D., Horne, M., Morrison, W., Egan, G., 2010, Retrograde axonal tracing using manganese enhanced magnetic resonance imaging, Neuroimage [P], vol 50, Academic Press, United States, pp. 366-374.

Akhlaghi, H., Corben, L., Georgiou-Karistianis, N., Bradshaw, J., Storey, E., Delatycki, M., Egan, G., 2010, Superior cerebellar peduncle atrophy in Friedreich's ataxia correlates with disease symptoms, Cerebellum [P], vol 10, issue 1, Springer, USA, pp. 81-87.

Yucel, M., Zalesky, A., Takagi, M., Bora, E., Fornito, A., Ditchfield, M., Egan, G., Pantelis, C., Lubman, D., 2010, White-matter abnormalities in adolescents with long-term inhalant and cannabis use: A diffusion magnetic resonance imaging study, Journal Of Psychiatry & Neuroscience [P], vol 35, issue 6, Canadian Medical Association, Canada, pp. 409-412.

Geng, G., Johnston, L.A., Yan, E., Britto, J.M., Smith, D.W., Walker, D.W., Egan, G.F., 2009, Biomechanisms for modelling cerebral cortical folding, Medical Image Analysis, vol 13, issue 6, Elseiver BV, The Netherlands, pp. 920-930.

Xiong, J., Ma, L., Wang, B., Narayana, S., Duff, E., Egan, G., Fox, P., 2009, Long-term motor training induced changes in regional cerebral blood flow in both task and resting states, Neuroimage [P], vol 45, issue 1, Academic Press, US, pp. 75-82.

Thompson, D., Wood, S., Doyle, L., Warfield, S., Egan, G., Inder, T., 2009, MR-Determined hippocampal asymmetry in full-term and preterm neonates, Hippocampus [P], vol 19, Wiley & Sons, US, pp. 118-123.

Bouilleret, V., Hogan, R., Velakoulis, D., Salzberg, M., Wang, L., Egan, G., O'Brien, T., Jones, N., 2009, Morphometric abnormalities and hyperanxiety in genetically epileptic rats: a model of psychiatric comorbidity?, Neuroimage [P], vol 45, issue 2, Academic Press, US, pp. 267-274.

Dominquez-Duque, J., Turner, R., Lewis, D., Egan, G., 2009, Neuroanthropology: A humanistic science for the study of the culture-brain nexus, Social Cognitive and Affective Neuroscience [E], vol 5, Oxford, UK, pp. 138-147.

Kolbe, S., Chapman, C., Nguyen, T., Bajraszewski, C., Johnston, L., Kean, M., Mitchell, P., Paine, M., Butzkueven, H., Kilpatrick, T., Egan, G., 2009, Optic nerve diffusion changes and atrophy jointly predict visual dysfunction after optic neuritis, Neuroimage [P], vol 45, issue 3, Academic Press, USA, pp. 679-686.

Dominquez-Duque, J., Lewis, D., Turner, R., Egan, G., 2009, The brain in culture and culture in the brain: a review of core issues in neuroanthropology, Progress in Brain Research [P], vol 178, Elsevier, USA, pp. 43-64.

Denton, D., McKinley, M., Farrell, M., Egan, G., 2009, The role of primordial emotions in the evolutionary origin of consciousness, Consciousness And Cognition [P], vol 18, issue 2, Eslevier, US, pp. 500-514.

Fitzgerald, P.B., Srithiran, A., Benitez, J., Daskalakis, Z.J., Oxley, T.J., Kulkarni, J., Egan, G.F., 2008, An fMRI study of prefrontal brain activation during multiple tasks in patients with major depressive disorder, Human Brain Mapping, vol 29, issue 4, John Wiley & Sons, Inc., USA, pp. 490-501.

Weisinger, H., Begg, D., Egan, G., Jayasooriya, A., Lie, F., Mathai, M., Sinclair, A., Wark, J., Weisinger, R., 2008, Angiotensin converting enzyme inhibition from birth reduces body weight and body fat in Sprague-Dawley rats, Physiology and Behavior [P], vol 93, issue 4-5, Elsevier, US, pp. 820-825.

Farrell, M., Zammarripa, F., Shade, R., _, _., McKinley, M., Fox, P., Denton, D., Egan, G., 2008, Effect of aging on regional cerebral blood flow responses associated with osmotic thirst and its satiation by water drinking: A PET study, Proceedings of the National Academy of Sciences of the United States of America [E], vol 105, National Academy of Sciences, USA, pp. 382-387.

Gavrilescu, M., Stuart, G.W., Rossell, S.L., Henshall, K., McKay, C., Sergejew, A., Copolov, D.L., Egan, G.F., 2008, Functional connectivity estimation in fMRI data: Influence of preprocessing and time course selection, Human Brain Mapping, vol 29, issue 9, John Wiley & Sons, Inc., USA, pp. 1040-1052.

Marriott, M., Emery, B., Cate, H., Binder, M., Kemper, D., Wu, Q., Kolbe, S., Gordon, I., Wang, H., Egan, G., Murray, S., Butzkueven, H., Kilpatrick, T., 2008, Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair, Glia [P], vol 56, Wiley & sons, USA, pp. 686-698.

Wu, Q., Yang, Q., Cate, M., Binder, M., Wang, H., Fang, K., Mariott, M., Kilpatrick, T., Egan, G., 2008, MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model, Journal Of Magnetic Resonance Imaging [P], vol 27, Wiley & Sons, USA, pp. 446-453.

Bohanna, I.K., Georgiou-Karistianis, N., Hannan, A.J., Egan, G.F., 2008, Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease, Brain Research Reviews, vol 58, issue 1, Elsevier BV, Netherlands, pp. 209-225.

Jayasooriya, A., Mathai, M., Walker, L., Begg, D., Denton, D., Cameron-Smith, D., Egan, G., McKinley, M., Rodger, P., Sinclair, A., Wark, J., Weisinger, H., Jois, M., Weisinger, R., 2008, Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 105, issue 18, National Academicy of Sciences, US, pp. 6531-6536.

Thompson, D., Wood, S., Doyle, L., Warfield, S., Lodygensky, G., Anderson, P., Egan, G., Inder, T., 2008, Neonate hippocampal volumes: Prematurity, perinatal predictors, and 2-year outcome, Annals Of Neurology [P], vol 63, John Wiley & Sons, USA, pp. 642-651.

Van Horn, J., Bandettini, P., Cheng, K., Egan, G., Stenger, V., Strother, S., Toga, A., 2008, New horizons for the next era of human brain imaging, cognitive, and behavioral research: pacific rim interactivity, Brain Imaging and Behavior [P], vol 2, issue 24, Springer, US, pp. 227-231.

Johnston, L., Duff, E., Mareels, I., Egan, G., 2008, Nonlinear estimation of the BOLD signal, Neuroimage [P], vol 40, Elsevier, usa, pp. 504-514.

Beauchamp, M., Thompson, D., Howard, K., Doyle, L., Egan, G., Inder, T., Anderson, P., 2008, Preterm infant hippocampal volumes correlate with later working memory deficits, Brain [P], vol 131, Oxford University Press, UK, pp. 2986-2994.

Carey, L., Abbott, D., Egan, G., Donnan, G., 2008, Reproducible activation in BA2, 1 and 3b associated with texture discrimination in healthy volunteers over time, Neuroimage [P], vol 39, Academic Press, US, pp. 40-51.

Duff, E., Johnston, L., Xiong, J., Fox, P., Mareels, I., Egan, G., 2008, The power of spectral density analysis for mapping endogenous BOLD signal fluctuations, Human Brain Mapping [E], vol 29, Wiley-Liss, USA, pp. 778-790.

Butzkueven, H., Kolbe, S.C., Jolley, D.J., Brown, J.Y., Cook, M.J., van der Mei, I., Groom, P.S., Carey, J., Eckholdt, J., Rubio, J., Taylor, B.V., Mitchell, P.J., Egan, G.F., Kilpatrick, T.J., 2008, Validation of linear cerebral atrophy markers in multiple sclerosis, Journal of Clinical Neuroscience, vol 15, Churchill Livingstone, UK, pp. 130-137.

Fitzgerald, P.B., Sritharan, A., Benitez, J., Daskalakis, Z.J., Jackson, G., Kulkarni, J., Egan, G.F., 2007, A preliminary fMRI study of the effects on cortical activation of the treatment of refractory auditory hallucinations with rTMS, Psychiatry Research Neuroimaging, vol 155, issue 1, Elsevier Ireland Ltd, Ireland, pp. 83-88.

Gantois, I., Fang, K., Jiang, L., Babovic, D., Lawrence, A.J., Ferreri, V., Teper, Y., Jupp, B., Ziebell, J.M., Morganti-Kossmann, M.C., O'Brien, T.J., Nally, R., Schutz, G., Waddington, J., Egan, G.F., Drago, J., 2007, Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior, Proceedings of the National Academy of Sciences of the United States of America, vol 104, issue 10, National Academy of Sciences, USA, pp. 4182-4187.

Yucel, M., Brewer, W.J., Harrison, B.J., Fornito, A., O'Keefe, G.J., Olver, J., Scott, A.M., Egan, G.F., Velakoulis, D., McGorry, P.D., Pantelis, C., 2007, Anterior cingulate activation in antipsychotic-naive first-episode schizophrenia, Acta Psychiatrica Scandinavica, vol 115, issue 2, Blackwell Publishing, Oxford UK, pp. 155-158.

Duff, E., Xiong, J., Wang, B., Cunnington, R., Fox, P., Egan, G., 2007, Complex spatio-temporal dynamics of fMRI BOLD: A study of motor learning, Neuroimage [P], vol 34, Academic Press, United States, pp. 156-168.

Shea, T., Sergejew, A., Burnham, D., Jones, C., Rossell, S.L., Copolov, D.L., Egan, G.F., 2007, Emotional prosodic processing in auditory hallucinations, Schizophrenia Research [P], vol 90, issue 1, Elsevier, Netherlands, pp. 214-220.

Thiruvady, D.R., Georgiou-Karistianis, N., Egan, G.F., Ray, S., Sritharan, A., Farrow, M.A., Churchyard, A.J., Chua, P., Bradshaw, J.L., Brawn, T., Cunnington, R., 2007, Functional connectivity of the prefrontal cortex in Huntington's disease, Journal of Neurology, Neurosurgery & Psychiatry, vol 78, BMJ Publishing Group, London England, pp. 127-133.

Georgiou-Karistianis, N., Sritharan, A., Farrow, M., Cunnington, R., Stout, J.C., Bradshaw, J.L., Churchyard, A.J., Brawn, T., Chua, P., Chiu, E., Thiruvady, D.R., Egan, G., 2007, Increased cortical recruitment in Huntington's disease using a Simon task, Neuropsycholgia, vol 45, issue 8, Pergamon-Elsevier Science Ltd, UK, pp. 1791-1800.

Brewer, W., Yucel, M., Harrison, B., McGorry, P., Olver, J., Egan, G., Velakoulis, D., Pantelis, C., 2007, Increased prefrontal cerebral blood flow in first-episode schizophrenia following treatment: longitudinal positron emission tomography study, Australian And New Zealand Journal Of Psychiatry [P], vol 41, Sage, UK, pp. 129-135.

Wu, Q., Butzkueven, H., Gresle, M., Kirchhoff, F., Friedhuber, A., Yang, Q., Wang, H., Fang, K., Lei, H., Egan, G., Kilpatrick, T., 2007, MR diffusion changes correlate with ultra-structurally defined axonal degeneration in murine optic nerve, Neuroimage [P], vol 37, Academic Press, United States, pp. 1138-1147.

Walters, N., Eickhoff, S., Schleicher, A., Zilles, K., Amunts, K., Egan, G., Watson, J., 2007, Observer-independent analysis of high-resolution MR images of the human cerebral cortex: In vivo delineation of cortical areas, Human Brain Mapping [P], vol 28, John Wiley & Sons, Inc., United States, pp. 1-8.

Thompson, D., Warfield, S., Carlin, J., Pavlovic, M., Wang, H., Bear, M., Kean, M., Doyle, L., Egan, G., Inder, T., 2007, Perinatal risk factors altering regional brain structure in the preterm infant, Brain [P], vol 130, Oxford University Press, United Kingdom, pp. 667-677.

Mazzone, S., McLennan, L., McGovern, A., Egan, G., Farrell, M., 2007, Representation of Capsaicin-evoked urge-to-cough in the human brain using functional magnetic resonance imaging, American Journal Of Respiratory And Critical Care Medicine [P], vol 176, American Thoracic Society, United States, pp. 327-332.

Chapman, H., Pierno, A., Cunnington, R., Gavrilescu, M., Egan, G., Castiello, U., 2007, The neural basis of selection-for-action, Neuroscience Letters [P], vol 417, Elsevier Ireland, Ireland, pp. 171-175.

Fitzgerald, P.B., Oxley, T.J., Laird, A.R., Kulkarni, J., Egan, G.F., Daskalakis, Z.J., 2006, An analysis of functional neuroimaging studies of dorsolateral prefrontal cortical activity in depression, Psychiatry Research: Neuroimaging, vol 148, issue 1, Elsevier Ireland Ltd, Shannon Ireland, pp. 33-45.

Harrison, B.J., Yucel, M., Shaw, M., Brewer, W.J., Nathan, P.J., Strother, S., Olver, J.S., Egan, G.F., Velakoulis, D., McGorry, P.D., Pantelis, C., 2006, Dysfunction of dorsolateral prefrontal cortex in antipsychotic-naive schizophreniform psychosis, Psychiatry Research: Neuroimaging, vol 148, issue 1, Elsevier, East Park Shannon Ireland, pp. 23-31.

Carey, L., Abbott, D., Egan, G., O'Keefe, G., Jackson, G., Bernhardt, J., Donnan, G., 2006, Evolution of brain activation with good and poor motor recovery after stroke, Neurorehabilitation and Neural Repair [P], vol 20, issue 1, Sage Publications, INc., United States, pp. 24-41.

McAllen, R., Farrell, M., Johnson, J., Trevaks, D., Cole, L., McKinley, M., Jackson, G., Denton, D., Egan, G., 2006, Human medullary responses to cooling and rewarming the skin: A functional MRI study, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 103, issue 3, National Academy of Sciences, United States, pp. 809-813.

Poline, J., Strother, S., Dehaene-Lambertz, G., Egan, G., Lancaster, J., 2006, Motivation and synthesis of the FIAC experiment: Reproducibility of fMRI results across expert analyses, Human Brain Mapping [P], vol 27, John Wiley & Sons, Inc., United States, pp. 351-359.

Cole, L., Farrell, M., Duff, E., Barber, J., Egan, G., Gibson, S., 2006, Pain sensitivity and fMRI pain-related brain activity in Alzheimer's disease, Brain [P], vol 129, Oxford University press, United Kingdom, pp. 2957-2965.

Johnston, L., Duff, E., Egan, G., 2006, Particle filtering for nonlinear BOLD signal analysis, Lecture Notes in Computer Science [P], vol 4191, Springer, Germany, pp. 292-299.

Farrell, M., Egan, G., Zamarripa, F., Shade, R., Blair-West, J., Fox, P., Denton, D., 2006, Unique, common, and interacting cortical correlates of thirst and pain, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 103, issue 7, National Academy of Sciences, United States, pp. 2416-2421.

Silk, T., Rinehart, N.J., Bradshaw, J.L., Tonge, B.J., Egan, G.F., O'Boyle, M., Cunnington, R., 2006, Visuospatial processing and the function of prefrontal-parietal networks in autism spectrum disorders: a functional MRI study, American Journal of Psychiatry, vol 163, issue 8, American Psychiatric Publishing, Inc., Arlington USA, pp. 1440-1443.

Weber, D., Clark, C., McFarlane, A., Moores, K., Morris, P., Egan, G., 2005, Abnormal frontal and parietal activity during working memory updating in post-traumatic stress disorder, Psychiatry Research - Neuroimaging [P], vol 140, Elsevier Ireland Ltd, Ireland, pp. 27-44.

Farrell, M., Laird, A., Egan, G., 2005, Brain activity associated with painfully hot stimuli applied to the upper limb: A meta-analysis, Human Brain Mapping [P], vol 25, John Wiley & Sons, Inc., United States, pp. 129-139.

Egan, G., Johnson, J., Farrell, M., McAllen, R., Zamarripa, F., McKinley, M., Lancaster, J., Denton, D., Fox, P., 2005, Cortical, thalamic, and hypothalamic responses to cooling and warming the skin in awake humans: A positron-emission tomography study, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 102, issue 14, National Academy of Sciences, United States, pp. 5262-5267.

Sritharan, A., Line, P., Sergejew, A., Silberstein, R., Egan, G., Copolov, D., 2005, EEG coherence measures during auditory hallucinations in schizophrenia, Psychiatry Research [P], vol 136, Elsevier Ireland Ltd, Ireland, pp. 189-200.

Silk, T., Vance, A., Rinehart, N.J., Egan, G.F., O'Boyle, M., Bradshaw, J.L., Cunnington, R., 2005, Fronto-parietal activation in attention-deficit hyperactivity disorder, combined type: functional magnetic resonance imaging study, British Journal of Psychiatry, vol 187, issue 12, Royal College of Psychiatrists, London UK, pp. 282-283.

Harrison, B., Shaw, M., Yucel, M., Purcell, R., Brewer, W., Strother, S., Egan, G., Olver, J., Nathan, P., Pantelis, C., 2005, Functional connectivity during Stroop Task Performance, Neuroimage [P], vol 24, Elsevier, USA, pp. 181-191.

Eickhoff, S., Walters, N., Schleicher, A., Kril, J., Egan, G., Zilles, K., Watson, J., Amunts, K., 2005, High-resolution MRI reflects myeloarchitecture and cytoarchitecture of human cerebral cortex, Human Brain Mapping [P], vol 24, John Wiley & Sons, Inc., United States, pp. 206-215.

O'Boyle, M., Cunnington, R., Silk, T., Vaughan, D., Jackson, G., Syngeniotis, A., Egan, G., 2005, Mathematically gifted male adolescents activate a unique brain network during mental rotation, Cognitive Brain Research [P], vol 25, Elsevier BV, Netherlands, pp. 583-587.

Carey, L., Abbott, D., Egan, G., Bernhardt, J., Donnan, G., 2005, Motor impairment and recovery in the upper limb after stroke: Behavioral and neuroanatomical correlates, Stroke [P], vol 36, Lippincott Williams & Wilkins, United States, pp. 625-629.

Podzebenko, K., Egan, G., Watson, J., 2005, Real and imaginary rotary motion processing: Functional parcellation of the human parietal lobe revealed by fMRI, Journal Of Cognitive Neuroscience [P], vol 17, issue 1, M I T Press, United States, pp. 24-36.

Gavrilescu, M., Stuart, G., Waites, A., Jackson, G., Svalbe, I.D., Egan, G.F., 2004, Changes in effective connectivity models in the presence of task-correlated motion: An fMRI study, Human Brain Mapping, vol 21, issue 2, Wiley-Liss, Inc., Hoboken NJ USA, pp. 49-63.

Zang, D.W., Yang, Q., Wang, H., Egan, G.F., Lopes, E.C., Cheema, S., 2004, Magnetic resonance imaging reveals neuronal degeneration in the brainstem of the superoxide dismutase 1G92A G1H transgenic mouse model of amyotrophic lateral sclerosis, European Journal of Neuroscience, vol 20, Blackwell Publishing Ltd, Oxford England, pp. 1745-1751.

McKinley, M.J., Cairns, M.J., Denton, D.A., Egan, G.F., Mathai, M.L., Uschakov, A., Wade, J.D., Weisinger, R.S., Oldfield, B.J., 2004, Physiological and pathophysiological influences on thirst, Physiology and Behavior [P], vol 81, issue 5, Elsevier Inc., USA, pp. 795-803.

Copolov, D.L., Seal, M.L., Maruff, P., Ulusoy, R., Wong, M.T.H., Tochon-Danguy, H., Egan, G.F., 2003, Cortical activation associated with the experience of auditory hallucinations and perception of human speech in schizophrenia: a PET correlation study, Psychiatry Research [P], vol 122, issue 3, Elsevier Ireland Ltd, Ireland, pp. 139-152.

Gavrilescu, M., Shaw, M.E., Stuart, G., Eckersley, P., Svalbe, I.D., Egan, G.F., 2002, Simulation of the effects of global normalization procedures in functional MRI, NeuroImage, vol 17, issue 2, Elsevier Science, USA, pp. 532-542.

Cunnington, R., Egan, G.F., O'Sullivan, J.D., Hughes, A., Bradshaw, J.L., Colebatch, J.G., 2001, Motor imagery in Parkinson's disease: a PET study, Movement Disorders, vol 16, issue 5, Wiley-Liss, New York NY USA, pp. 849-857.

Conference Proceedings

Killeen, N., Lohrey, J., Farrell, M., Liu, W., Garic, S., Abramson, D.A., Nguyen, H.A., Egan, G.F., 2012, Integration of modern data management practice with scientific workflows, 2012 IEEE 8th International Conference on eScience, 8 October 2012 to 12 October 2012, IEEE, Piscataway NJ USA, pp. 1-8.

Johnston, L.A., Kolbe, S., Mareels, I.M.Y., Egan, G., 2008, Voxelwise regularisation of high angular resolution diffusion imaging data, IEEE Engineering in Medicine and Biology Society, 20-24 August 2008, The Printing House Inc, USA, pp. 90-93.

Fitzgerald, P.B., Sritharan, A., Benitez, J., Daskalakis, Z.J., De Castella, R.A., Kulkarni, J., Egan, G., 2006, An fMRI study of the effects of low and high frequency transcranial magnetic stimulation treatment in depression, BIOLOGICAL PSYCHIATRY, Elsevier Science Inc, USA, p. 129S.

Kolbe, S., Ma, T., Liu, W., Soh, W., Buyya, R., Egan, G., 2005, A Platform for Distributed Analysis of Neuroimaging Data on Global Grids, First International Conference on e-Science and Grid Computing, 5-8 December 2005, IEEE Computer Society Conference Publishing Services, USA, pp. 79-86.

Silk, T., Rinehart, N.J., Bradshaw, J.L., Tonge, B.J., Egan, G.F., O'Boyle, M., Cunnington, R., 2005, Functional MR Imaging of visuo-spatial network in Autism Spectrum Disorder, Australian Journal of Psychology: Combined Abstracts of 2005 Australian Psychology Conferences, 28 September 2005 - 2 October 2005, Taylor & Francis Ltd, Vic Australia, p. 254.

Sritharan, A., Egan, G., Davis, J.R., Wells, P., 1999, Enhancement of Image SNR for the Measurement of rCBF with PET, Proceedings of the Inaugural Conference of the Victorian Chapter of the IEEE Engineering in Medicine and Biology Society, Melbourne 22-23 February 1999, IEEE, Australia, pp. 1-7.

Cunnington, R., Egan, G., O'Sullivan, J.D., Hughes, A., Bradshaw, J.L., Colebatch, J.G., 1999, Motor imagery in Parkinson's disease: A PET study, Neuroimage (Supplement), Dusseldorf, Germany 22-26 June 1999, Academic Press Inc, London UK, p. 561.

Cunnington, R., Hughes, A.J., O'Sullivan, J.D., Egan, G., Bradshaw, J.L., Colebatch, J.G., 1998, Motor Imagery in Parkinson's disease patients "on" and "off" apomorphine: A PET study, Abstracts of the 5th International Congress of Parkinson's Disease and Movement Disorders (Published in Movement Disorders Journal), New York USA 10-14 October 1998, Lippincott Willliams & Wilkins, Philadelphia USA, p. 5.082.

O'Sullivan, J.D., Cunnington, R., Egan, G., Hughes, A.J., Colebatch, J.G., 1998, Thalamocortical activity during motor imagery in PD after pallidotomy, Abstracts of the 5th International Congress of Parkinson's Disease and Movement Disorders (Published in Movement Disorders Journal), New York USA 10-14 October 1998, Lippincott Williams & Wilkins, Philadelphia USA, p. 1.247.

Wells, P., Sritharan, A., Egan, G., Davis, J.R., 1997, An iterative approach to PET image impovement, Proc. Permit '97 Conference, Adelaide, SA, 8-11 Sept. 1997, Australasian Radiation Protection Society, Adelaide SA Australia, p. 19A-1.

Sritharan, A., Egan, G., Wells, P., Davis, J.R., 1997, Application of iterative image reconstruction to functional brain mapping, Digital Image and Vision Computing: Techniques and Applications, Albany, New Zealand, 10-12 December 1997, Massey University,, New Zealand, pp. 437-442.

Postgraduate Research Supervisions

Completed Supervision

Student:

Gavrilescu, M.

Program of Study:

EVALUATION OF THE EFFECTS OF CONFOUNDS ON THE PREPROCESSING AND EFFECTIVE CONNECTIVITY ANALYSIS OF FUNCTIONAL NEUROIMAGING DATA. (PHD) 2003.

Supervisors:

Svalbe, I (Main), Egan, G (Associate).