Dr Oded Kleifeld - Researcher Profile

Biography

Oded works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: Weizmann Institute of Science - Israel

Year awarded: 2004

Publications

Book Chapters

Doucet, A., Kleifeld, O., Kizhakkedathu, J., Overall, C.M., 2011, Identification of proteolytic products and natural protein N-termini by Terminal Amine Isotopic Labeling of Substrates (TAILS), in Methods in Molecular Biology - Gel-Free Proteomices, eds K Gevaert & J Vandekerckhove, Humana Press, USA, pp. 273-287.

Journal Articles

Singh, R.K., Zerath, S., Kleifeld, O., Scheffner, M., Glickman, M.H., Fushman, D., 2012, Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system, Molecular & Cellular Proteomics [P], vol 11, issue 12, American Society for Biochemistry and Molecular Biology Inc., USA, pp. 1595-1611.

Ziv, I., Matiuhin, Y., Kirkpatrick, D.S., Erpapazoglu, Z., Leon, S., Pantazopoulou, M., Kim, W., Gygi, S., Haguenauer-Tsapis, R., Reis, N., Glickman, M.H., Kleifeld, O., 2011, A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis, Molecular & Cellular Proteomics [P], vol 10, issue 5, American Society for Biochemistry & Molecular Biology Inc, USA, pp. M111.009753-1-M111.009753-22.

Yu, Z., Kleifeld, O., Lande-Atir, A., Bsoul, M., Kleiman, M., Krutauz, D., Book, A., Vierstra, R.D., Hofmann, K., Reis, N., Glickman, M.H., 2011, Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome, Molecular Biology of the Cell [P], vol 22, issue 7, American Society for Cell Biology, USA, pp. 911-920.

Kleifeld, O., Doucet, A., Prudova, A., auf dem Keller, U., Gioia, M., Kizhakkedathu, J., Overall, C.M., 2011, Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates, Nature Protocols [P], vol 6, issue 10, Nature Publishing Group, UK, pp. 1578-1611.

Savulescu, A.F., Shorer, H., Kleifeld, O., Cohen, I., Gruber, R., Glickman, M.H., Harel, A., 2011, Nuclear import of an intact preassembled proteasome particle, Molecular Biology of the Cell [P], vol 22, issue 6, American Society for Cell Biology, USA, pp. 880-891.

Keren-Kaplan, T., Attali, I., Motamedchaboki, K., Davis, B.A., Tanner, N., Reshef, Y., Laudon, E., Kolot, M., Levin-Kravets, O., Kleifeld, O., Glickman, M.H., Horazdovsky, B.F., Wolf, D.A., Prag, G., 2011, Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria, Embo Journal [P], vol 31, issue 2, Nature Publishing Group, UK, pp. 378-390.

Kleifeld, O., Doucet, A., auf dem Keller, U., Prudova, A., Schilling, O., Kainthan, R.K., Starr, A.E., Foster, L.J., Kizhakkedathu, J., Overall, C.M., 2010, Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products, Nature Biotechnology [P], vol 28, issue 3, Nature Publishing Group, USA, pp. 281-288.

Ziv, I., Kleifeld, O., Glickman, M.H., 2009, Nonconformity in ubiquitin compliance, Embo Journal [P], vol 28, issue 13, Nature Publishig Group, UK, pp. 1825-1827.

Sha, Z., Brill, L.M., Cabrera, R., Kleifeld, O., Scheliga, J.S., Glickman, M.H., Chang, E.C., Wolf, D.A., 2009, The eIF3 interactome reveals the translasome, a supercomplex linking protein synthesis and degradation machineries, Molecular Cell [P], vol 36, issue 1, Cell Press, USA, pp. 141-152.

Matiuhin, Y., Kirkpatrick, D.S., Ziv, I., Kim, W., Dakshinamurthy, A., Kleifeld, O., Gygi, S., Reis, N., Glickman, M.H., 2008, Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome, Molecular Cell [P], vol 32, issue 3, Cell Press, USA, pp. 415-425.

Overall, C.M., Kleifeld, O., 2006, Towards third generation matrix metalloproteinase inhibitors for cancer therapy, British Journal Of Cancer [P], vol 94, issue 7, Nature Publishing Group, UK, pp. 941-946.

Overall, C.M., Kleifeld, O., 2006, Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy, Nature Reviews Cancer [P], vol 6, issue 3, Nature Publishing Group, UK, pp. 227-239.