Dr Hugh Reid - Researcher Profile

Biography

Hugh works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: University of Melbourne

Year awarded: 1991

BACHELOR OF SCIENCE (HONOURS)

Institution: Monash University

Year awarded: 1985

Publications

Journal Articles

Broughton, S.E., Petersen, J., Theodossis, A., Scally, S.W., Loh, K.L., Thompson, A., van Bergen, J., Kooy-Winkelaar, Y., Henderson, K.N., Beddoe, T.C., Tye-Din, J.A., Mannering, S.I., Purcell, A.W., McCluskey, J., Anderson, R.P., Koning, F., Reid, H.H., Rossjohn, J., 2012, Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease, Immunity [P], vol 37, issue 4, Cell Press, USA, pp. 611-621.

Zhang, X., Liu, J., Shi, Y., Reid, H.H., Boyd, R.L., Khattabi, M., El-Omrani, H.Y., Zheng, P., Liu, Y., Bai, X., 2012, CD24 on thymic APCs regulates negative selection of myelin antigen-specific T lymphocytes, European Journal Of Immunology [P], vol 42, issue 4, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 924-935.

Vivian, J.P., Duncan, R.C., Berry, R., O'Connor, G.M., Reid, H.H., Beddoe, T.C., Gras, S., Saunders, P.M., Olshina, M.A., Widjaja, J.M., Harpur, C.M., Lin, J., Maloveste, S.M., Price, D.A., Lafont, B.A., McVicar, D.W., Clements, C.S., Brooks, A.G., Rossjohn, J., 2011, Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B, Nature [P], vol 479, issue 7373, Nature Publishing Group, UK, pp. 401-405.

Pellicci, D.G., Patel, O., Kjer-Nielsen, L., Pang, S.S., Sullivan, L.C., Kyparissoudis, K., Brooks, A.G., Reid, H.H., Gras, S., Lucet, I.S., Koh, R., Smyth, M.J., Mallevaey, T., Matsuda, J.L., Gapin, L., McCluskey, J., Godfrey, D.I., Rossjohn, J., 2009, Differential Recognition of CD1d-alpha-Galactosyl Ceramide by the Vbeta8.2 and Vbeta7 Semi-invariant NKT T Cell Receptors, Immunity [P], vol 31, issue 1, Cell Press, USA, pp. 47-59.

Petersen, J., Wurzbacher, S.J., Williamson, N.A., Ramarathinam, S.H., Reid, H.H., Nair, A.K.N., Zhao, A.Y., Nastovska, R., Rudge, G., Rossjohn, J., Purcell, A.W., 2009, Phosphorylated self-peptides alter human leukocyte antigen class l-restricted antigen presentation and generate tumor-specific epitopes, Proceedings of the National Academy of Sciences of the United States of America, vol 106, issue 8, National Academy of Sciences, USA, pp. 2776-2781.

Hopkins, E.J., Clements, C.S., Lin, J., Sullivan, L.C., Johnson, D., Huyton, T., Heroux, A., Hoare, H.L., Beddoe, T.C., Reid, H.H., Wilce, M.C., Brooks, A., Rossjohn, J., 2008, CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence, The Journal of Experimental Medicine, vol 205, issue 3, Rockefeller University Press, United States, pp. 725-735.

Hoare, H.L., Sullivan, L.C., Clements, C.S., Ely, L.K., Beddoe, T.C., Henderson, K., Lin, J., Reid, H.H., Brooks, A., Rossjohn, J., 2008, Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors, Journal of Molecular Biology, vol 377, issue 5, Academic Press, United Kingdom, pp. 1297-1303.

Tynan, F.E., Reid, H.H., Kjer-Nielsen, L., Miles, J.J., Wilce, M.C.J., Kostenko, L., Borg, N., Williamson, N.A., Beddoe, T.C., Purcell, A.W., Burrows, S.R., McCluskey, J., Rossjohn, J., 2007, A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule, Nature Immunology, vol 8, issue 3, Nature Publishing Group, New York NY USA, pp. 268-276.

Henderson, K., Tye-Din, J.A., Reid, H.H., Chen, Z., Borg, N., Beissbarth, T., Tatham, A., Mannering, S.I., Purcell, A.W., Dudek, N.L., van Heel, D.A., McCluskey, J., Rossjohn, J., Anderson, R.P., 2007, A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease, Immunity, vol 27, issue 1, Cell Press, Cambridge MA USA, pp. 23-34.

Sullivan, L.C., Clements, C.S., Beddoe, T.C., Johnson, D., Hoare, H.L., Lin, J., Huyton, T., Hopkins, E.J., Reid, H.H., Wilce, M.C.J., Kabat, J., Borrego, F., Coligan, J.E., Rossjohn, J., Brooks, A., 2007, The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition, Immunity, vol 27, issue 6, Cell Press, Cambridge MA USA, pp. 900-911.

Henderson, K., Reid, H.H., Borg, N., Broughton, S.E., Huyton, T., Anderson, R.P., McCluskey, J., Rossjohn, J., 2007, The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease, Acta Crystallographica Section F-Structural Biology and Crystallization Communications, vol 63, issue 12, Wiley-Blackwell Munksgaard, Denmark, pp. 1021-1025.

Huntington, N.D., Tomioka, R., Clavarino, C., Chow, A.M., Linares, D., Mana, P., Rossjohn, J., Cachero, T.G., Qian, F., Kalled, S.L., Bernard, C.C.A., Reid, H.H., 2006, A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses, International Immunology, vol 18, issue 10, Oxford University Press, Oxford UK, pp. 1473-1485.

Kjer-Nielsen, L., Borg, N.A., Pellicci, D.G., Beddoe, T.C., Kostenko, L., Clements, C.S., Williamson, N.A., Smyth, M.J., Besra, G.S., Reid, H.H., Bharadwaj, M., Godfrey, D.I., Rossjohn, J., McCluskey, J., 2006, A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition, Journal of Experimental Medicine, vol 203, issue 3, Rockefeller University Press, New York USA, pp. 661-673.

Hoare, H.L., Sullivan, L.C., Pietra, G., Clements, C.S., Lee, E.J., Ely, L.K., Beddoe, T.C., Falco, M., Kjer-Nielsen, L., Reid, H.H., McCluskey, J., Moretta, L., Rossjohn, J., Brooks, A.G., 2006, Structural basis for a major histocompatibility complex class Ib-restricted T cell response, Nature Immunology, vol 7, issue 3, Nature Publishing Group, New York USA, pp. 256-264.

Borg, N.A., Ely, L.K., Beddoe, T.C., Macdonald, W.A., Reid, H.H., Clements, C.S., Purcell, A.W., Kjer-Nielsen, L., Miles, J.J., Burrows, S.R., McCluskey, J., Rossjohn, J., 2005, The CDR3 regions of an Immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition, Nature Immunology, vol 6, issue 2, Nature Publishing Group, New York USA, pp. 171-180.

Pereira, J.J., Meyer, T., Docherty, S.E., Reid, H.H., Marshall, J., Thompson, E.W., Rossjohn, J., Price, J.T., 2004, Bimolecular interaction of Insulin-Like Growth Factor (IGF) binding Protein-2 with 3 negatively modulates IGF-I-Mediated migration and tumor growth, Cancer Research, vol 64, issue 3, American Association of Cancer Research, Philadelphia USA, pp. 977-984.

Clements, C.S., Reid, H.H., Beddoe, T.C., Tynan, F.E., Perugini, M., Johns, T.G., Bernard, C.C.A., Rossjohn, J., 2003, The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis, Proceedings of the National Academy of Sciences of the United States of America, vol 100, issue 19, National Academy of Sciences, Washington USA, pp. 11059-11064.

Linares, D., Mana, P., Goodyear, M., Chow, A.M., Clavarino, C., Huntington, N.D., Barnett, L., Koentgen, F., Tomioka, R., Bernard, C.C.A., Freire-Garabal, M., Reid, H.H., 2003, The magnitude and encephalogenic potential of autoimmune response to MOG is enhanced in MOG deficient mice, Journal of Autoimmunity, vol 21, issue 4, Academic Press, UK, pp. 339-351.

McQualter, J.L., Darwiche, R., Ewing, C., Onuki, M., Kay, T.W., Hamilton, J.A., Reid, H.H., Bernard, C.C., 2001, Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis, Journal of Experimental Medicine, vol 194, issue 7, Rockefeller University Press, New York USA, pp. 873-881.

Conference Proceedings

Kjer-Nielsen, L., Beddoe, T.C., Kostenko, L., Clements, C.S., Williamson, N.A., Besra, G.S., Reid, H.H., Bharadwaj, M., Godfrey, D.I., McCluskey, J., Rossjohn, J., 2005, A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1D-mediated antigen recognition, Tissue Antigens, 29 November 2005 - 3rd December 2005, Blackwell Publishing, Oxford England, p. 365.

Hoare, H.L., Sullivan, L.C., Pietra, G., Clements, C.S., Beddoe, T.C., Kjer-Nielsen, L., Reid, H.H., McCluskey, J., Moretta, L., Rossjohn, J., 2005, Recognition of the non-classical MHC class I molecule, HLA-E, by the adaptive immune system, Tissue Antigens, 29 November 2005 - 3rd December 2005, Blackwell Publishing, Oxford England, p. 443.

Other

Kalled, S.L., Reid, H.H., 2003, Use of BMCA as an immunoregulatory agent, Australia.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Structural basis for citrullination dependent rheumatoid arthritis.

Supervisors:

Rossjohn, J (Main), Reid, H (Associate).

Completed Supervision

Student:

Broughton, S.

Program of Study:

Structural insights into the CD4+ T cell response to the alpha1-gliadin peptide in celiac disease. (PHD) 2010.

Supervisors:

Rossjohn, J (Main), Reid, H (Associate).

Student:

Xu, A.

Program of Study:

. 2010.

Supervisors:

Rossjohn, J (Main), Reid, H (Associate).