Dr Mhairi Maxwell - Researcher Profile

Biography

Mhairi works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: Monash University

Year awarded: 2005

BACHELOR OF BIOMEDICAL SCIENCE (HONOURS)

Institution: Monash University

Year awarded: 2001

Publications

Journal Articles

Maxwell, M.J., Tsantikos, E., Kong, A.M., Vanhaesebroeck, B., Tarlinton, D.M., Hibbs, M., 2012, Attenuation of phosphoinositide 3-kinase delta signaling restrains autoimmune disease, Journal Of Autoimmunity [P], vol 38, issue 4, Academic Press, United Kingdom, pp. 381-391.

Duan, M., Li, W.C., Vlahos, R., Maxwell, M.J., Anderson, G., Hibbs, M., 2012, Distinct macrophage subpopulations characterize acute infection and chronic inflammatory lung disease, Journal Of Immunology [P], vol 189, issue 2, American Association of Immunologists, United States, pp. 946-955.

Tsantikos, E., Maxwell, M.J., Kountouri, N., Harder, K.W., Tarlinton, D.M., Hibbs, M., 2012, Genetic interdependence of lyn and negative regulators of B cell receptor signalling in autoimmune disease development, Journal Of Immunology [P], vol 189, issue 4, American Association of Immunologists, United States, pp. 1726-1736.

Lau, M., Tsantikos, E., Maxwell, M.J., Tarlinton, D.M., Anderson, G., Hibbs, M., 2012, Loss of STAT6 promotes autoimmune disease and atopy on a susceptible genetic background, Journal Of Autoimmunity [P], vol 39, issue 4, Academic Press, United Kingdom, pp. 388-397.

Nguyen, N., Maxwell, M., Ooms, L., Davies, E.M., Hilton, A., Collinge, J., Hilton, D., Kile, B., Mitchell, C., Hibbs, M., Jane, S., Curtis, D., 2011, An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation, Blood [P], vol 117, issue 20, American Society of Hematology, United States, pp. 5362-5371.

Maxwell, M., Duan, M., Armes, J., Anderson, G., Tarlinton, D., Hibbs, M., 2011, Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice, Journal Of Immunology [P], vol 186, issue 12, American Association of Immunologists, USA, pp. 7164-7175.

Verhagen, A., Wallace, M., Goradia, A., Jones, S., Croom, H., Metcalf, D., Collinge, J., Maxwell, M., Hibbs, M., Alexander, W., Hilton, D., Kile, B., Starr, R., 2009, A kinase-dead allele of lyn attenuates autoimmune disease normally associated with lyn deficiency, Journal Of Immunology [P], vol 182, American Association of Immunologist, 9650 Rockville Pike, Bethersda MD 20814 USA, pp. 2020-2029.

Maxwell, M.J., Westein, E., Nesbitt, W.S., Giuliano, S., Dopheide, S.M., Jackson, S., 2007, Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation, Blood, vol 109, issue 2, American Society of Hematology, USA, pp. 566-576.

Schoenwaelder, S.M., Ono, A., Sturgeon, S.A., Chan, S.M., Mangin, P., Maxwell, M.J., Turnbull, S., Mulchandani, M., Anderson, K.E., Kauffenstein, G., Rewcastle, G.W., Kendall, J., Gachet, C., Salem, H.H., Jackson, S., 2007, Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin aIIb?3 adhesive function in platelets, The Journal of Biological Chemistry, vol 282, issue 39, The American Society for Biochemistry and Molecular Biology Inc, USA, pp. 28648-28658.

Maxwell, M.J., Dopheide, S.M., Turner, S.J., Jackson, S., 2006, Shear induces a unique series of morphological changes in translocating platelets: effects of morphology on translocation dynamics, Arteriosclerosis, Thrombosis, and Vascular Biology, vol 26, issue 3, Lippincott Williams and Wilkins, Philadelphia USA, pp. 663-669.

Maxwell, M.J., Yuan, Y., Anderson, K.E., Hibbs, M.L., Salem, H.H., Jackson, S.P., 2004, SHIP1 and Lyn kinase negatively regulate integrin IIb3 signaling in platelets, The Journal of Biological Chemistry, vol 279, issue 31, The American Society for Biochemistry and Molecular Biology,c, USA, pp. 32196-32204.

Dopheide, S.M., Maxwell, M.J., Jackson, S.P., 2002, Shear-dependent tether formation during platelet translocation on von Willebrand factor, Blood, vol 99, issue 1, The American Society of Hematology, Washington DC USA, pp. 159-167.