Dr Courtney Judkins - Researcher Profile

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Address

Department of Pharmacology
Faculty of Medicine, Nursing & Health Sciences, Clayton

Qualifications

Unknown
Institution: Monash University
Year awarded: 2004

Publications

Journal Articles

Sobey, C.G., Judkins, C.P., Rivera, J., Lewis, C., Diep, H., Lee, H.W., Kemp-Harper, B.K., Broughton, B.R.S., Selemidis, S., Gaspari, T.A., Samuel, C.S., Drummond, G.R., 2015, NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis, Free Radical Research [P], vol 49, issue 2, Taylor & Francis, UK, pp. 186-198.

Sobey, C.G., Judkins, C.P., Sundararajan, V., Phan, T.G., Drummond, G.R., Srikanth, V.K., 2015, Risk of major cardiovascular events in people with down syndrome, PLoS ONE [E], vol 10, issue 9 (Art. No: e0137093), Public Library of Science, USA, pp. 1-11.

Miller, A.A., De Silva, T.M., Judkins, C.P., Diep, H., Drummond, G.R., Sobey, C.G., 2010, Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia, Stroke [P], vol 41, issue 4, Lippincott Williams & Wilkins, USA, pp. 784-789.

Judkins, C.P., Diep, H., Broughton, B.R.S., Mast, A., Hooker, E.U., Miller, A.A., Selemidis, S., Dusting, G.J., Sobey, C.G., Drummond, G.R., 2010, Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE -/- mice, American Journal Of Physiology-Heart And Circulatory Physiology [P], vol 298, issue 1, American Physiological Society, USA, pp. H-24-H-32.

Judkins, C.P., Sobey, C.G., Dang, T.T., Miller, A.A., Dusting, G.J., Drummond, G.R., 2006, NADPH-induced contractions of mouse aorta do not involve NADPH oxidase: a role for P2X receptors, The Journal of Pharmacology and Experimental Therapeutics, vol 317, issue 2, The American Society for Pharmacology and Experimental Therapeutics, Bethesda Maryland USA, pp. 644-650.

Halls, M.L., Bond, C.P., Sudo, S., Kumagai, J., Ferraro, T., Layfield, S., Bathgate, R.A.D., Summers, R.J., 2005, Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8), The Journal of Pharmacology and Experimental Therapeutics, vol 313, issue 2, The American Society for Pharmacology and Experimental Therapeutics, Bethesda USA, pp. 677-687.

Bond, C.P., Parry, L.J., Samuel, C.S., Gehring, H.M., Lederman, F.L., Rogers, P.A.W., Summers, R.J., 2004, Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle, Journal of Clinical Endocrinology & Metabolism, vol 89, issue 7, Endocrine Society, USA, pp. 3477-3485.

Samuel, C.S., Zhao, C., Bond, C.P., Hewitson, T.D., Amento, E.P., Summers, R.J., 2004, Relaxin-1-deficient mice develop an age-related progression of renal fibrosis, Kidney International, vol 65, issue 6, Blackwell Publishing, USA, pp. 2054-2064.

Samuel, C.S., Zhao, C., Bathgate, R.A.D., Bond, C.P., Burton, M.D., Parry, L.J., Summers, R.J., Tang, M.L.K., Amento, E.P., Tregear, G.W., 2003, Relaxin deficiency in mice is associated with an age-related progression of pulmonary fibrosis, FASEB Journal, vol 17, issue 1, Federation of the American Society of Experimental Biology, Bethesda USA, pp. 121-123.

Bathgate, R., Samuel, C.S., Burazin, T.C., Layfield, S., Claasz, A.A., Reytomas, I.G., Dawson, N.F., Zhao, C., Bond, C.P., Summers, R.J., Parry, L.J., Wade, J.D., Tregear, G.W., 2002, Human Relaxin Gene 3 (H3) and the Equivalent Mouse Relaxin (M3) Gene, The Journal of Biological Chemistry, vol 277, American Society of Biochemistry and Molecular Biology Inc., Bethesda NS USA, pp. 1148-1157.

Claasz, A.A., Bond, C.P., Bathgate, R., Otvos Jnr, L., Dawson, N.F., Summers, R.J., Tregear, G.W., Wade, J.D., 2002, Relaxin-Like bioactivity of Ovine Insulin 3 (INSL3) Analogues, European Journal of Biochemistry, vol 269, issue 24, Blackwell, Oxford England, pp. 6287-6293.

Tan, Y.Y., Dawson, N.F., Kompa, A., Bond, C.P., Claasz, A.A., Wade, J.D., Tregear, G.W., Summers, R.J., 2002, Structural requirements for the interaction of sheep insulin-like factor 3 with relaxin receptors in rat atria, European Journal of Pharmacology, vol 457, issue 2-Mar, Elsevier Science, Amsterdam Netherlands, pp. 153-160.

Mathieu, M., Wade, J.D., Catimel, B., Bond, C.P., Nice, E.C., Summers, R.J., Otvos Jnr, L., Tregear, G.W., 2001, Synthesis, conformational studies and biological activity of Na -mono-biotinylated rat relaxin, Journal of Peptide Research, vol 57, issue 5, Munksgaard Int Publ Ltd, Copenhagen Denmark, pp. 374-382.

Conference Proceedings

Halls, M.L., Bathgate, R., Sudo, S., Kumagai, J., Bond, C.P., Summers, R.J., 2005, Identification of binding sites with differing affinity and potency for relaxin analogues on LGR7 and LGR8 receptors, Relaxin and Related Peptides: Fourth International Conference, 05 September 2004 to 10 September 2004, New York Academy of Sciences, New York USA, pp. 17-21.

Bond, C.P., Parry, L.J., Samuel, C.S., Gehring, H., Lederman, F.L., Rogers, P.A.W., Summers, R.J., 2005, Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle, Relaxin and Related Peptides: Fourth International Conference, 5 September 2004 to 10 September 2004, New York Academy of Sciences, New York USA, pp. 136-143.

Bond, C.P., Widdop, R.E., Hodgson, W.C., 1999, Modulation of angiotensin II reactivity in the vasculature of diabetic rats, Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists, 1 December 1999 to 1 December 1999, ASCEPT, Sydney NSW Australia, pp. 82-Post 1-19.

Grants

Title:
A novel nanoparticle-based approach to gene silencing in vivo: extravasation of siRNA via albumin.
Investigators:
White, P, Boyd, B, Pouton, C, Graham, B, Judkins, C
Funding:
(2010 - 2011). Heart Foundation of Australia [heartfoundation, AUS, VIC].
Title:
Defining the roles of NADPH oxidases in vascular remodelling and arterial hypertension.
Investigators:
Judkins, C
Funding:
(2007 - 2008). Heart Foundation of Australia [heartfoundation, AUS, VIC].
Title:
Relaxin: Molecular mechanisms of action in the reversal of fibrosis.
Investigators:
Summers, R, Tregear, G, Bathgate, R, Samuel, C, Du, X, Tang, M, Judkins, C, Gao, X
Funding:
(2005 - 2007). Australian Research Council (ARC) [arc, AUS, ACT].
(2005 - 2007). BASS Medical Inc [bassmed, USA, AL].