Assoc Prof Robert Andrews - Researcher Profile

Biography

Robert works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Senior Research Fellow.

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Related Links:

• ACBD site

Research & Supervision Interests

Current research involves translation of laboratory-based studies of platelet receptors to analysis of clinical samples from patients with atherothrombotic disease, coagulopathy, cancer, autoimmune thrombocytopenia or other immunological or haematological defects. 

Keywords

Biomedical Research, Multidisciplinary, Haematology, Platelets, Vascular Biology, Receptors, Biomarkers, Toxins

Qualifications

DOCTOR OF PHILOSOPHY

Institution: University of Queensland, St Lucia, Queensla

Year awarded: 1986

BACHELOR OF SCIENCE WITH HONOURS CLASS 1

Institution: University of Queensland - QLD

Year awarded: 1982

BACHELOR OF SCIENCE

Institution: University of Queensland - QLD

Year awarded: 1981

Publications

Book Chapters

Gardiner, E.E., Al-Tamimi, M., Andrews, R.K., Berndt, M.C., 2012, Platelet receptor shedding, in Methods in Molecular Biology: Platelets and Megakaryocytes, eds Jonathan M. Gibbins, Martyn P. Mahaut-Smith, Springer, United States, pp. 321-339.

Andrews, R.K., Berndt, M.C., Lopez, J.A., 2006, The glycoprotein Ib-IX-V complex, in Platelets, eds Alan D Michelson, Academic Press, USA, pp. 145-163.

Andrews, R.K., Gardiner, E.E., Berndt, M.C., 2004, Snake venom toxins affecting platelet function, in Platelets and Megakaryocytes Volume 2: Perspectives and Techniques, eds Jonathan M Gibbins and Martyn P Mahaut-Smith, Totowa Humana Press, USA, pp. 335-348.

Journal Articles

Qiao, J.L., Arthur, J.F., Collecutt, M., Shen, Y., Mu, F., Berndt, M.C., Davis, A., Andrews, R.K., Gardiner, E.E., 2012, An acquired defect associated with abnormal signaling of the platelet collagen receptor glycoprotein VI, Acta Haematologica [P], vol 128, issue 4, S. Karger AG, Switzerland, pp. 233-241.

Al-Tamimi, M., Arthur, J.F., Gardiner, E.E., Andrews, R.K., 2012, Focusing on plasma glycoprotein VI, Thrombosis and Haemostasis [P], vol 107, issue 4, Schattauer GmbH, Germany, pp. 648-655.

Arthur, J.F., Qiao, J.L., Shen, Y., Davis, A., Dunne, E., Berndt, M.C., Gardiner, E.E., Andrews, R.K., 2012, ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways, Journal Of Thrombosis And Haemostasis [P], vol 10, issue 6, Wiley-Blackwell Publishing Ltd., UK, pp. 1133-1141.

Andrews, R., Gardiner, E., 2012, Inside platelets..., Blood [P], vol 119, American Society of Hematology, Washington, DC 20036 United States, pp. 907-909.

Gardiner, E.E., Andrews, R.K., 2012, Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction, Blood Reviews [P], vol 26, issue 6, Churchill Livingstone, United Kingdom, pp. 255-259.

Al-Tamimi, M., Tan, C., Qiao, J.L., Pennings, G., Javadzadegan, A., Yong, A., Arthur, J.F., Davis, A., Jing, J., Mu, F., Hamilton, J.R., Jackson, S., Ludwig, A., Berndt, M.C., Ward, C., Kritharides, L., Andrews, R.K., Gardiner, E.E., 2012, Pathologic shear triggers shedding of vascular receptors: A novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels, Blood [P], vol 119, issue 18, American Society of Hematology, United States, pp. 4311-4320.

Gardiner, E., Al-Tamimi, M., Andrews, R., Berndt, M., 2012, Platelets and Megakaryocytes: volume 3, Additional Protocols and Perspectives, Methods in Molecular Biology, Methods in Molecular Biology, vol 788, Humana Press, United States, pp. 321-339.

Gardiner, E., Ward, C., Andrews, R., 2012, The NET effect of clot formation, Journal Of Thrombosis And Haemostasis [P], vol 10, Wiley-Blackwell Publishing Ltd, Oxford, OX4 2DQ United Kingdom, pp. 133-135.

Andrews, R., Berndt, M., 2011, An event of shear importance, Blood [P], vol 117, issue 1, American Society of Hematology, Washington, DC 20036 United States, pp. 5-7.

Schoenwaelder, S., Jarman, K., Gardiner, E., Hua, M., Qiao, J., White, M., Josefsson, E., Alwis, I., Ono, A., Willcox, A., Andrews, R., Mason, K., Salem, H., Huang, D., Kile, B., Roberts, A., Jackson, S., 2011, Bcl-x L-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets, Blood [P], vol 118, issue 6, American Society of Hematology, USA, pp. 1663-1674.

Berndt, M., Andrews, R., 2011, Bernard-Soulier syndrome, Haematologica-The Hematology Journal [P], vol 96, issue 3, Fondazione Ferrata Storti, Pavia, PV 27100 Italy, pp. 355-359.

Al-Tamimi, M., Grigoriadis, G., Tran, H., Paul, E., Servadei, E.P., Berndt, M., Gardiner, E.E., Andrews, R.K., 2011, Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa, Blood [P], vol 117, issue 14, American Society of Hematology, United States, pp. 3912-3920.

Cranmer, S., Ashworth, K., Yao, Y., Berndt, M.C., ruggeri, Z.M., Andrews, R., Jackson, S., 2011, High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIba-filamin interaction, Blood [P], vol 117, issue 9, American Society of Hematology, United States, pp. 2718-2727.

Andrews, R., Berndt, M., Elalamy, I., 2011, Platelets - From function to dysfunction in essential thrombocythaemia, European Oncology & Haematology [P], vol 7, issue 2, Touch Briefings, UK, pp. 125-131.

Al-Tamimi, M., Gardiner, E., Thom, J., Shen, Y., Cooper, M., Hankey, G., Berndt, M., Baker, R., Andrews, R., 2011, Soluble glycoprotein VI is raised in the plasma of patients with acute ischemic stroke, Stroke [P], vol 42, issue 2, Lippincott Williams & Wilkins, Philadelphia, PA 19106 United States, pp. 498-500.

Arthur, J., Shen, Y., Gardiner, E., Coleman, L., Kenny, D., Andrews, R., Berndt, M.C., 2011, TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets, Journal of Thrombosis and Haemostasis [E], vol 9, issue 1, Wiley-Blackwell Publishing Ltd, United Kingdom, United States, pp. 163-172.

Berndt, M., Andrews, R., 2011, Thrombotic thrombocytopenic purpura: Reducing the risk?, European Journal Of Clinical Investigation [P], vol 121, issue 2, American Society for Clinical Investigation, Ann Arbor, MI 48107 United States, pp. 522-524.

Mu, F.-., Cranmer, S.L., Andrews, R.K., Berndt, M.C., 2010, Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibalpha, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex, Journal Of Thrombosis And Haemostasis [P], vol 8, issue 2, Wiley-Blackwell Publishing Ltd, United Kingdom, United States, pp. 324-330.

Gardiner, E.E., Arthur, J.F., Shen, Y., Karunakaran, D., Moore, L.A., Am Esch II, J.S., Andrews, R.K., Berndt, M.C., 2010, GPIb-selective activation of platelets induces platelet signaling events comparable to GPVI activation events, Platelets [P], vol 21, issue 4, Informa Healthcare, United Kingdom, pp. 244-252.

Wijeyewickrema, L.C., Gardiner, E.E., Gladigau, E.L., Berndt, M.C., Andrews, R.K., 2010, Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI, Journal Of Biological Chemistry [P], vol 285, issue 16, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 11793-11799.

Qiao, J., Shen, Y., Gardiner, E., Andrews, R., 2010, Proteolysis of platelet receptors in humans and other species., Biological Chemistry [P], vol 391, Walter de Gruyter GmbH & Co. KG, Germany, pp. 893-900.

Gardiner, E., Berndt, M., Andrews, R., 2010, Restored platelet function after romiplostim treatment in a patient with immune thrombocytopenic purpura, British Journal Of Haematology [P], vol 149, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 620-630.

Mo, X., Nguyen, N.X., Mu, F.-., Yang, W., Luo, S.-., Fan, H., Andrews, R.K., Berndt, M.C., Li, R., 2010, Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha, Journal Of Biological Chemistry [P], vol 285, issue 42, American Society for Biochemistry and Molecular Biology, Inc., United States, pp. 32096-32104.

Al-Tamimi, M., Mu, F., Arthur, J.F., Shen, Y., Moroi, M., Berndt, M.C., Andrews, R.K., Gardiner, E.E., 2009, Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding, Platelets [P], vol 20, issue 2, Informa Healthcare, UK, pp. 75-82.

McEwan, P.A., Andrews, R.K., Emsley, J., 2009, Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism, Blood [P], vol 114, issue 23, American Society of Hematology, USA, pp. 4883-4885.

Al-Tamimi, M., Mu, F., Moroi, M., Gardiner, E.E., Berndt, M.C., Andrews, R.K., 2009, Measuring soluble platelet glycoprotein VI in human plasma by ELISA, Platelets [P], vol 20, issue 3, Informa Healthcare, UK, pp. 143-149.

Wei, A., Schoenwaelder, S.M., Andrews, R.K., Jackson, S., 2009, New insights into the haemostatic function of platelets, British Journal Of Haematology [P], vol 147, issue 4, Wiley-Blackwell Publishing Ltd, UK, pp. 415-430.

Lai, Z.W., Lew, R.A., Yarski, M.A., Mu, F., Andrews, R.K., Smith, A.I., 2009, The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2, Endocrinology, vol 150, issue 5, The Endocrine Society, USA, pp. 2376-2381.

Mu, F., Andrews, R.K., Arthur, J.F., Munday, A.D., Cranmer, S.L., Jackson, S., Stomski, F.C., Lopez, A.F., Berndt, M.C., 2008, A functional 14-3-3{zeta}-independent association of PI3-kinase with glycoprotein Ib{alpha}, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex, Blood, vol 111, issue 9, American Society of Hematology, United States, pp. 4580-4587.

Buzza, M.S., Dyson, J.M., Choi, H., Gardiner, E.E., Andrews, R.K., Kaiserman, D., Mitchell, C.A., Berndt, M.C., Dong, J., Bird, P.I., 2008, Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor, Journal of Biological Chemsitry, vol 283, issue 33, American Society for Biochemistry and Molecular Biology, Inc., United States, pp. 22498-22504.

Gardiner, E.E., Al-Tamimi, M., Mu, F., Karunakaran, D., Thom, J., Moroi, M., Andrews, R.K., Berndt, M.C., 2008, Compromised ITAM-based platelet receptor function in a patient with immune thrombocytopenic purpura, Journal of Thrombosis and Haemostasis, vol 6, issue 7, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 1175-1182.

Gardiner, E.E., Karunakaran, D., Arthur, J.F., Mu, F., Powell, M.S., Baker, R.I., Hogarth, P.M., Kahn, M.L., Andrews, R.K., Berndt, M.C., 2008, Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: De-ITAM-izing Fc gammaRIIa, Blood, vol 111, American Society of Hematology, USA, pp. 165-174.

Andrews, R.K., Berndt, M.C., 2008, Microparticles facilitate neutrophil/platelet crosstalk., Blood, vol 112, issue 5, American Society of Hematology, United States, pp. 2174-2175.

Berndt, M.C., Andrews, R.K., 2008, New direction for WE thrombin, Arteriosclerosis, Thrombosis, and Vascular Biology, vol 28, issue 2, Lippincott Williams and Wilkins, USA, pp. 205-207.

Andrews, R.K., Berndt, M.C., 2008, Platelet adhesion: a game of catch and release., Journal of Clinical Investigation, vol 118, issue 9, American Society for Clinical Investigation, United States, pp. 3009-3011.

Arthur, J.F., Gardiner, E.E., Kenny, D., Andrews, R.K., Berndt, M.C., 2008, Platelet receptor redox regulation, Platelets [P], vol 19, issue 1, Informa Healthcare, United Kingdom, pp. 1-8.

Berndt, M.C., Andrews, R.K., 2008, Systems biology meets platelet biology, Blood, vol 112, issue 10, American Society of Hematology, United States, pp. 3920-3921.

Gardiner, E.E., Andrews, R.K., 2008, The cut of the clot(h): Snake venom fibrinogenases as therapeutic agents, Journal of Thrombosis and Haemostasis, vol 6, issue 8, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 1360-1362.

Dunkley, S., Arthur, J.F., Evans, S., Gardiner, E.E., Shen, Y., Andrews, R.K., 2007, A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway, British Journal of Haematology, vol 137, issue 6, Wiley-Blackwell Publishing Ltd, UK, pp. 569-577.

Gardiner, E.E., Karunakaran, D., Shen, Y., Arthur, J.F., Andrews, R.K., Berndt, M.C., 2007, Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases, Journal of thrombosis and haemostasis, vol 5, issue 7, Wiley-Blackwell Publishing, UK, pp. 1530-1537.

Wijeyewickrema, L.C., Gardiner, E.E., Shen, Y., Berndt, M.C., Andrews, R.K., 2007, Fractionation of snake venom metalloproteinases by metal ion affinity: A purified cobra metalloproteinase, Nk, from Naja kaouthia binds Ni2+-agarose, Toxicon, vol 50, issue 8, Pergamon-Elsevier Science Ltd, Oxford England UK, pp. 1064-1072.

Berndt, M.C., Andrews, R.K., 2007, Full clot retraction: running on mTOR, Blood, vol 109, issue 5, American Society of Hematology, USA, pp. 1791-1792.

Arthur, J.F., Shen, Y., Kahn, M.L., Berndt, M.C., Andrews, R.K., Gardiner, E.E., 2007, Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane, The Journal of Biological Chemistry, vol 282, issue 42, American society for biochemistry and molecular biology, Inc, United states, pp. 30434-30441.

Arthur, J.F., Dunkley, S., Andrews, R.K., 2007, Platelet glycoprotein VI-related clinical defects, British Journal of Haematology, vol 139, issue 3, Blackwell Scientific Publications, UK, pp. 363-372.

Andrews, R.K., Karunakaran, D., Gardiner, E.E., Berndt, M.C., 2007, Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity, Arteriosclerosis Thrombosis and Vascular Biology, vol 27, issue 7, Lippincott Williams and Wilkins, USA, pp. 1511-1520.

Berndt, M.C., Karunakaran, D., Gardiner, E.E., Andrews, R.K., 2007, Programmed autologous cleavage of platelet receptors, Journal of Thrombosis and Haemostasis, vol 5, issue 1, Blackwell Publishing, United Kingdom, pp. 212-219.

Wijeyewickrema, L.C., Gardiner, E.E., Moroi, M., Berndt, M.C., Andrews, R.K., 2007, Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI, Thrombosis & Haemostasis, vol 98, issue 6, Schattauer GMBH, Stuttgart Germany, pp. 1285-1290.

Andrews, R.K., Du, X., Berndt, M.C., 2007, The 14-3-3zeta-GPIb-IX-V complex as an antiplatelet target, Drug News and Perspectives, vol 20, issue 5, Prous Science, Spain, pp. 285-292.

Shi, T., Giannakopoulos, B.M., Yan, X., Yu, P., Berndt, M.C., Andrews, R.K., Rivera, J., Iverson, G.M., Cockerill, K.A., Linnik, M.D., Krilis, S.A., 2006, Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V, Arthritis & Rheumatism, vol 54, issue 8, Wiley-Liss, Div John Wiley & Sons Inc, Hoboken NJ USA, pp. 2558-2567.

Arthur, J.F., Shen, Y., Mu, F., Leon, C., Gachet, C., Berndt, M.C., Andrews, R.K., 2006, Calmodulin interacts with the platelet ADP receptor P2Y1, Biochemical Journal, vol 398, issue 3, Portland Press Ltd, London England UK, pp. 339-343.

Berndt, M.C., Cranmer, S.L., Andrews, R.K., 2006, Filamin A interaction with GP1balpha: The platelet shapes up, Blood, vol 107, issue 5, American Society of Hematology, Washington DC USA, p. 1745.

Shen, Y., Cranmer, S.L., Aprico, A., Whisstock, J., Jackson, S., Berndt, M.C., Andrews, R.K., 2006, Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor, The Journal of Biological Chemistry, vol 281, issue 36, American Society for Biochemistry and Molecular Biology, Inc, Bethesda USA, pp. 26419-26423.

Arthur, J.F., Gardiner, E.E., Matzaris, M., Taylor, S.G., Wijeyewickrema, L.C., Ozaki, Y., Kahn, M.L., Andrews, R.K., Berndt, M.C., 2005, Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets, Thrombosis and Haemostasis, vol 93, issue 4, Schattauer GmbH-Verlag Medizin Naturwissenschaften, Stuttgart Germany, pp. 716-723.

Yip, J., Shen, Y., Berndt, M.C., Andrews, R.K., 2005, Primary platelet adhesion receptors, IUBMB Life, vol 57, issue 2, Taylor & Francis, Inc., Philadelphia USA, pp. 103-108.

Gardiner, E.E., Arthur, J.F., Berndt, M.C., Andrews, R.K., 2005, Role of calmodulin in platelet receptor function, Current Medicinal Chemistry-Cardiovascular & Hematological Agents, vol 3, issue 3, Bentham Science Publishers Ltd, Sharjah United Arab Emirates, pp. 173-179.

Wijeyewickrema, L.C., Berndt, M.C., Andrews, R.K., 2005, Snake venom probes of platelet adhesion receptors and their ligands, Toxicon, vol 45, issue 8, Pergamon-Elsevier Science Ltd, Kidlington England, pp. 1051-1061.

Andrews, R.K., Gardiner, E.E., Shen, Y., Berndt, M.C., 2004, Platelet interactions in thrombosis, IUBMB Life, vol 56, issue 1, Taylor & Francis Inc., Philadelphia USA, pp. 13-18.

Andrews, R.K., Berndt, M.C., 2004, Platelet physiology and thrombosis, Thrombosis Research, vol 114, issue 5-6, Pergamon-Elsevier Science Ltd, Kidlington UK, pp. 447-453.

Gardiner, E.E., Arthur, J.F., Kahn, M.L., Berndt, M.C., Andrews, R.K., 2004, Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase, Blood, vol 104, issue 12, American Society of Hematology, Washington USA, pp. 3611-3617.

Andrews, R.K., Gardiner, E.E., Shen, Y., Whisstock, J.C., Berndt, M.C., 2003, Molecules in focus: glycoprotein Ib-IX-V, The International Journal of Biochemistry & Cell Biology, vol 35, issue 8, Permagon-Elsevier Science Ltd, Kidlington England, pp. 1170-1174.

Andrews, R.K., Berndt, M.C., 2003, Platelet physiology: in cold blood, Current Biology, vol 13, issue 7, Cell Press, Cambridge USA, pp. 282-284.

Suzuki-Inoue, K., Tulasne, D., Shen, Y., Bori-Sanz, T., Inoue, O., Jung, S.M., Moroi, M., Andrews, R.K., Berndt, M.C., Watson, S.P., 2002, Association of Fyn and Lyn with the Proline-rich domain of glycoprotein VI regulates intracellular signaling, The Journal of Biological Chemistry, vol 277, issue 24, American Society of Biochemistry & Molecular Biology Inc, Bethesda MD USA, pp. 21561-21566.

Shen, Y., Dong, J., Romo, G.M., Arceneaux, W., Aprico, A., Gardiner, E.E., Lopez, J.A., Berndt, M.C., Andrews, R.K., 2002, Functional analysis of the C-terminal flanking sequence of platelet glycoprotein Ibalpha using canine-human chimeras, Blood, vol 99, pp. 145*-150.

Andrews, R.K., Suzuki-Inoue, K., Shen, Y., Tulasne, D., Watson, S.P., Berndt, M.C., 2002, Interaction of calmodulin with cytoplasmic domain of platelet glycoprotein VI, Blood, vol 99, issue 11, American Society of Hmatology, Washington DC USA, pp. 4219-4221.

Whisstock, J.C., Shen, Y., Lopez, J.A., Andrews, R.K., Berndt, M.C., 2002, Molecular Modeling of the Seven Tandem Leucine-Rich Repeats within the Ligand-Binding Region of Platelet Glycoprotein Ib, Thrombosis and Haemostatis, vol 87, issue 2, Schattauer GMBH-Verlag, Stuttgart Germany, pp. 329-333.

De Candia, E., Hall, S.W., Rutella, S., Landolfi, R., Andrews, R.K., De Cristofaro, R., 2001, Binding of thrombin to glycoprotein Ib accelerates the hydrolysis of Par-1 on intact platelets, J Biol Chem, vol 276, pp. 4692*-4698.

Andrews, R.K., Munday, A.D., Mitchell, C.A., Berndt, M.C., 2001, Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex, Blood, vol 98, issue 3, American Society of Hematology, Washington DC USA, pp. 681-687.

Gardiner, E.E., De Luca, M., McNally, T., Michelson, A.D., Andrews, R.K., Berndt, M.C., 2001, Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor PSGL-1 by neutrophil elastase and cathepsin G, Blood, vol 98, pp. 1440*-1447.

Gardiner, E.E., De Luca, M., McNally, T., Michelson, A.D., Andrews, R.K., Berndt, M.C., 2001, Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor PSGL-1 by neutrophil elastase and cathepsin G, Blood, vol 98, pp. 1440*-1447.

Dong, J., Berndt, M.C., Schade, A., McIntire, L.V., Andrews, R.K., Lopez, J.A., 2001, Ristocetin-dependent, but not botrocetin-dependent, binding of von Willebrand factor to the platelet glycoprotein Ib-IX-V complex correlates with shear-dependent interactions, Blood, vol 97, issue 1, American Society of Hematology, USA, pp. 162-168.

Berndt, M.C., Shen, Y., Dopheide, S.M., Gardiner, E., Andrews, R.K., 2001, The Vascular Biology of the Glycoprotein Ib-IX-V Complex, Thrombosis and Haemostasis, vol 86, Schattauer GMBH Verlag Medizin Naturwissenschaften, Stuttgart Germany, pp. 178-188.

Asazuma, N., Marshall, S., Berlanga, O., Snell, D.L., Poole, A., Berndt, M.C., Andrews, R.K., Watson, S.P., 2001, The snake venom toxin alboaggregin-A activates GPVI, Blood, vol 97, pp. 3989*-3991.

Andrews, R.K., Gardiner, E.E., Asazuma, N., Berlanga, O., Nieswandt, B., Smith, A.I., Watson, S.P., Tulasne, D., Berndt, M.C., 2001, The viper venom metalloproteinase-disintegrin, Alborhagin, is an agonist at the platelet collagen receptor GPVI, J Biol Chem, vol 276, pp. 28092*-28097.

Shen, Y., Romo, G.M., Dong, J., Schade, A., McIntire, L.V., Kenny, D., Whisstock, J.C., Berndt, M.C., Lopez, J.A., Andrews, R.K., 2000, Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex, Blood, vol 95, pp. 903*-910.

De Luca, M., Facey, D.A., Favaloro, E.J., Hertzberg, M.S., Whisstock, J.C., McNally, T., Andrews, R.K., Berndt, M.C., 2000, Structure and function of the von Willebrand factor A1 domain: analysis with monoclonal antibodies reveals distinct binding sites involved in recognition of the platelet membrane glycoprotein Ib-IX-V complex and ristocetin-dependent activation, Blood, vol 95 issue 1, American Society for Hematology, Washington USA, pp. 164-172.

Campbell, J.K., Gurung, R., Romero, S., Speed, C.J., Andrews, R.K., Berndt, M.C., Miitchell, C.A., 1997, Activation of the 43 kDa Inositol Polyphospate 5 - Phosphatase by 14 - 3 - 3z, Biochemistry, vol 36, ACS Publications, Duke University Medical Centre, pp. 15363-15370.

Teaching Commitment

Cell Biology

Human Pathology

Community Service

Insititute Site Visits and Open Days

Clinical Activity

Nil

Activities

Editorships of academic journals

From: 01/07/2010 To: 25/09/2012
Monash
Section Editor
Thrombosis and Haemostasis

Faculty academic committee

From: 01/07/2008 To: 25/09/2012
Monash
Faculty Research Committee

Postgraduate Research Supervisions

Completed Supervision

Student:

Al-Tamimi, M.

Program of Study:

Transition of platelet receptor shedding: platelet-specific collagen receptor GPVI. (PHD) 2010.

Supervisors:

Andrews, R (Main), Gardiner, E (Associate).

Student:

Lai, Z.

Program of Study:

The characterisation of ectodomain shedding of angiotensin-converting enzyme 2 (ACE2). (PHD) 2010.

Supervisors:

Smith, A (Main), Andrews, R (Associate).

Student:

Mado, B.

Program of Study:

Evaluating bleeding risk in the context of infectious diseases. 2012.

Supervisors:

Andrews, R (Main).

Student:

Wijeyewickrema, L.

Program of Study:

Snake venom probes of platelet adhesion receptors and their ligands. (PHD) 2006.

Supervisors:

Andrews, R (Joint), Berndt, M (Joint-Co).