Dr Andrew Powell - Researcher Profile

Biography

Position

Operations Manager, Centre for Drug Candidate Optimisation

Research & Supervision Interests

• Lead optimisation and preclinical development of new drug candidates

Qualifications

GRADUATE CERTIFICATE IN MANAGEMENT

Institution: Chifley Business School

Year awarded: 2013

PHD (PHYSIOLOGY)

Institution: Monash University

Year awarded: 2003

HONOURS DEGREE OF BACHELOR OF SCIENCE (BIOMEDICAL)

Institution: Monash University

Year awarded: 2000

Publications

Journal Articles

Zhang, Y., Edgley, A.J., Cox, A.J., Powell, A.K., Wang, B.H., Kompa, A.R., Stapleton, D.I., Zammit, S.C., Williams, S.J., Krum, H., Gilbert, R.E., Kelly, D.J., 2012, FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomypathy, European Journal of Heart Failure [P], vol 14, Oxford University Press, Netherlands, pp. 549-562.

Hung, L., Villemagne, V., Cheng, L., Sherratt, N., Ayton, S., White, A., Crouch, P., Lim, S., Leong, S., Wilkins, S., George, J., Roberts, B., Pham, C., Liu, X., Chiu, F., Shackleford, D., Powell, A., Masters, C., Bush, A., O'Keefe, G., Culvenor, J., Cappai, R., Cherny, R., Donnelly, P., Hill, A., Finkelstein, D., Barnham, K., 2012, The hypoxia imaging agent CU(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease, Journal of Experimental Medicine [P], vol 209, issue 4, Rockefeller University Press, New York, pp. 837-854.

Soon, C., Donnelly, P., Turner, B., Hung, L., Crouch, P., Sherratt, N., Tan, J., Lim, N., Lam, L., Bica, L., Lim, S., Hickey, J., Morizzi, J., Powell, A., Finkelstein, D., Culvenor, J., Masters, C., Duce, J., White, A., Barnham, K., Lin, Q., 2011, Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII (atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model, Journal Of Biological Chemistry [P], vol 286, issue 51, American Society for Biochemistry and Molecular Biology, USA, pp. 44035-44044.

Burns, C., Fantino, E., Powell, A., Shnyder, S., Cooper, P., Nelson, S., Christophi, C., Malcontenti-Wilson, C., Dubljevic, V., Harte, M., Joffe, M., Phillips, I., Segal, D., Wilks, A., Smith, G., 2011, The microtubule depolymerising agent CYT997 causes extensive ablation of tumor vasculature in vivo, Journal Of Pharmacology And Experimental Therapeutics [P], vol 339, issue 3, The American Society for Pharmacology and Experimental Therapeutics, USA, pp. 799-806.

Powell, A.K., Fida, R., Bywater, R., 2003, Motility in the isolated mouse colon: migrating motor complexes, myoelectric complexes and pressure waves, Neurogastroenterology and Motility, vol 15, issue 3, Blackwell Publishing Ltd, Oxford UK, pp. 257-266.

Powell, A.K., Bywater, R., 2003, Murine intestinal migrating motor complexes: longitudinal components, Neurogastroenterology and Motility, vol 15, issue 3, Blackwell Publishing Ltd, Oxford UK, pp. 245-256.

Powell, A.K., O'Brien, S.D., Fida, R., Bywater, R., 2002, Neural integrity is essential for the propagation of colonic migrating motor complexes in the mouse, Neurogastroenterology and Motility, vol 14, issue 5, Blackwell Publishing Ltd, Oxford UK, pp. 495-504.

Powell, A.K., Bywater, R., 2001, Endogenous nitric oxide release modulates the direction and frequency of colonic migrating motor complexes in the isolated mouse colon, Neurogastroenterology and Motility, vol 13, issue 3, Blackwell Science Ltd, Oxford England, pp. 221-228.

Powell, A.K., Fida, R., Bywater, R., 2001, Ongoing nicotinic and non-nicotinic inputs to inhibitory neurons in the mouse colon, Clinical and Experimental Pharmacology and Physiology, vol 28, issue 10, Blackwell Science Asia, Carlton Vic Australia, pp. 792-798.