Dr Travis Beddoe - Researcher Profile

Biography

Travis works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Senior Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: Unknown

Year awarded: 2005

Publications

Journal Articles

Wang, H., Paton, J.C., Herdman, B.P., Rogers, T.J., Beddoe, T.C., Paton, A.W., 2013, The B Subunit of an AB5 Toxin Produced by Salmonella enterica Serovar Typhi Up-regulates Chemokines, Cytokines and Adhesion Molecules in Human Macrophage, Colonic Epithelial and Brain Microvascular Endothelial Cell Lines, Infection And Immunity [P], vol 81, issue 3, American Society for Microbiology, USA, pp. 673-683.

Broughton, S.E., Petersen, J., Theodossis, A., Scally, S.W., Loh, K.L., Thompson, A., van Bergen, J., Kooy-Winkelaar, Y., Henderson, K.N., Beddoe, T.C., Tye-Din, J.A., Mannering, S.I., Purcell, A.W., McCluskey, J., Anderson, R.P., Koning, F., Reid, H.H., Rossjohn, J., 2012, Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease, Immunity [P], vol 37, issue 4, Cell Press, USA, pp. 611-621.

Beddoe, T.C., Brooks, A.G., Rossjohn, J., 2011, How opposites attract, Immunology And Cell Biology [P], vol 89, issue 2, Nature Publishing Group, UK, pp. 163-164.

Vivian, J.P., Duncan, R.C., Berry, R., O'Connor, G.M., Reid, H.H., Beddoe, T.C., Gras, S., Saunders, P.M., Olshina, M.A., Widjaja, J.M., Harpur, C.M., Lin, J., Maloveste, S.M., Price, D.A., Lafont, B.A., McVicar, D.W., Clements, C.S., Brooks, A.G., Rossjohn, J., 2011, Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B, Nature [P], vol 479, issue 7373, Nature Publishing Group, UK, pp. 401-405.

Patel, O., Cameron, G., Pellicci, D., Liu, Z., Byun, H., Beddoe, T., McCluskey, J., Franck, R., Castano, A., Harrak, Y., Llebaria, A., Bittman, R., Porcelli, S., Godfrey, D., Rossjohn, J., 2011, NKT TCR recognition of CD1d-a-C-galactosylceramide, Journal Of Immunology [P], vol 187, issue 9, The American Association of Immunologists, Inc., USA, pp. 4705-4713.

Pellicci, D., Clarke, A., Patel, O., Mallevaey, T., Beddoe, T., Le Nours, J., Uldrich, A., McCluskey, J., Besra, G., Porcelli, S., Gapin, L., Godfrey, D., Rossjohn, J., 2011, Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors, Nature Immunology [P], vol 12, issue 9, Nature Publishing Group, USA, pp. 827-833.

Vivian, J., Riedmaier, P., Ge, H., Le Nours, J., Sansom, F.M., Wilce, M.C.J., Byres, E., Dias, M., Schmidberger, J., Cowan, P.J., d'Apice, A.J., Hartland, E.L., Rossjohn, J., Beddoe, T.C., 2010, Crystal Structure of a Legionella pneumophila Ecto -Triphosphate Diphosphohydrolase, A Structural and Functional Homolog of the Eukaryotic NTPDases, Structure [P], vol 18, issue 2, Cell Press, USA, pp. 228-238.

Scoble, J.A., McAlister, A.D., Fulton, Z.J., Troy, S.T., Byres, E., Vivian, J., Brammananth, R., Wilce, M.C.J., Le Nours, J., Zaker-Tabrizi, L., Coppel, R.L., Crellin, P., Rossjohn, J., Beddoe, T.C., 2010, Crystal structure and comparative functional analyses of a Mycobacterium aldo-keto reductase, Journal of Molecular Biology [P], vol 398, issue 1, Academic Press, UK, pp. 26-39.

Burrows, S.R., Chen, Z., Archbold, J.K., Tynan, F.E., Beddoe, T.C., Kjer-Nielsen, L., Miles, J.J., Khanna, R., Moss, D.J., Liu, Y.C., Gras, S., Kostenko, L., Brennan, R.M., Clements, C.S., Brooks, A.G., Purcell, A.W., McCluskey, J., Rossjohn, J., 2010, Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 107, issue 23, National Academy of Sciences, USA, pp. 10608-10613.

Beddoe, T.C., Paton, A.W., Le Nours, J., Rossjohn, J., Paton, J.C., 2010, Structure, biological functions and applications of the AB5 toxins, Trends In Biochemical Sciences [P], vol 35, issue 7, Elsevier Ltd, UK, Switzerland, pp. 411-418.

Crellin, P., Vivian, J., Scoble, J.A., Chow, F.M., West, N.P., Brammananth, R., Proellocks, N.I., Shahine, A.E., Le Nours, J., Wilce, M.C., Britton, W.J., Coppel, R.L., Rossjohn, J., Beddoe, T.C., 2010, Tetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viability, Journal Of Biological Chemistry [P], vol 285, issue 39, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 30050-30060.

Pang, S.S., Berry, R., Chen, Z., Kjer-Nielsen, L., Perugini, M.A., King, G.F., Wang, C., Chew, S.H., La Gruta, N.L., Williams, N.K., Beddoe, T.C., Tiganis, T., Cowieson, N.P., Godfrey, D.I., Purcell, A.W., Wilce, M.C., McCluskey, J., Rossjohn, J., 2010, The structural basis for autonomous dimerization of the pre-T-cell antigen receptor, Nature [P], vol 467, issue 7317, Nature Publishing Group, UK, pp. 844-848.

Beddoe, T.C., Chen, Z., Clements, C.S., Ely, L.K., Bushell, S.R., Vivian, J.P., Kjer-Nielsen, L., Pang, S.S., Dunstone, M.A., Liu, Y.C., Macdonald, W.A., Perugini, M.A., Wilce, M.C.J., Burrows, S.R., Purcell, A.W., Tiganis, T., Bottomley, S.P., McCluskey, J., Rossjohn, J., 2009, Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor, Immunity [P], vol 30, issue 6, Cell Press, USA, pp. 777-788.

Vivian, J., Beddoe, T.C., McAlister, A.D., Wilce, M.C.J., Zaker-Tabrizi, L., Troy, S.T., Byres, E., Hoke, D.E., Cullen, P.A., Lo, M., Murray, G.L., Adler, B., Rossjohn, J., 2009, Crystal structure of LipL32, the most abundant surface protein of pathogenic Leptospira spp., Journal of Molecular Biology, vol 387, issue 5, Academic Press, UK, pp. 1229-1238.

Archbold, J.K., Macdonald, W.A., Gras, S., Ely, L.K., Miles, J.J., Bell, M.J., Brennan, R.M., Beddoe, T.C., Wilce, M.C.J., Clements, C.S., Purcell, A.W., McCluskey, J., Burrows, S.R., Rossjohn, J., 2009, Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition, The Journal of Experimental Medicine, vol 206, issue 1, Rockefeller University Press, USA, pp. 209-219.

Vivian, J., Scoullar, J., Rimmer, K., Bushell, S.R., Beddoe, T.C., Wilce, M.C.J., Byres, E., Boyle, T.P., Doak, B.C., Simpson, J.S., Graham, B., Heras, B., Kahler, C.M., Rossjohn, J., Scanlon, M., 2009, Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis, Journal of Molecular Biology [P], vol 394, issue 5, Academic Press, UK, pp. 931-943.

Wun, K.S., Borg, N., Kjer-Nielsen, L., Beddoe, T.C., Koh, R., Richardson, S.K., Thakur, M., Howell, A.R., Scott-Browne, J.P., Gapin, L., Godfrey, D.I., McCluskey, J., Rossjohn, J., 2008, A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR, The Journal of Experimental Medicine, vol 205, issue 4, Rockefeller University Press, USA, pp. 939-949.

Hopkins, E.J., Clements, C.S., Lin, J., Sullivan, L.C., Johnson, D., Huyton, T., Heroux, A., Hoare, H.L., Beddoe, T.C., Reid, H.H., Wilce, M.C., Brooks, A., Rossjohn, J., 2008, CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence, The Journal of Experimental Medicine, vol 205, issue 3, Rockefeller University Press, United States, pp. 725-735.

Fulton, Z.J., McAlister, A.D., Wilce, M.C., Brammananth, R., Zaker-Tabrizi, L., Perugini, M.A., Bottomley, S.P., Coppel, R.L., Crellin, P., Rossjohn, J., Beddoe, T.C., 2008, Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species, Journal of Biological Chemistry, vol 283, issue 41, American Society for Biochemistry and Molecular Biology, Inc., United States, pp. 27881-27890.

Sansom, F.M., Riedmaier, P., Newton, H., Dunstone, M.A., Muller, C.E., Stephan, H., Byres, E., Beddoe, T.C., Rossjohn, J., Cowan, P.J., d'Apice, A.J.F., Robson, S.C., Hartland, E.L., 2008, Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: Substrate specificity and requirement for virulence, Journal of Biological Chemistry, vol 283, issue 19, American Society for Biochemistry and Molecular Biology, Inc., United States, pp. 12909-12918.

Fulton, Z.J., Crellin, P., Brammananth, R., Zaker-Tabrizi, L., Coppel, R.L., Rossjohn, J., Beddoe, T.C., 2008, Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria, Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, vol 64, issue Pt 5, Wiley-Blackwell Munksgaard, Denmark, pp. 428-431.

Byres, E., Paton, A.W., Paton, J.C., Lofling, J.C., Smith, D.F., Wilce, M.C.J., Talbot, U.M., Chong, D.C., Yu, H., Huang, S., Chen, X., Varki, N.M., Varki, A., Rossjohn, J., Beddoe, T.C., 2008, Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin, Nature, vol 456, issue 7222, Nature Publishing Group, United Kingdom, pp. 648-652.

Vivian, J., Scoullar, J., Robertson, A.L., Bottomley, S.P., Horne, H.J., Chin, K.Y., Wielens, J., Thompson, P., Velkov, T., Piek, S., Byres, E., Beddoe, T.C., Wilce, M.C., Kahler, C.M., Rossjohn, J., Scanlon, M., 2008, Structural and biochemical characterization of the oxidoreductase NmDsbA3 from Neisseria meningitidis, The Journal of Biological Chemistry, vol 283, issue 47, American Society for Biochemistry and Molecular Biology Inc., United States, pp. 32452-32461.

Hoare, H.L., Sullivan, L.C., Clements, C.S., Ely, L.K., Beddoe, T.C., Henderson, K., Lin, J., Reid, H.H., Brooks, A., Rossjohn, J., 2008, Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors, Journal of Molecular Biology, vol 377, issue 5, Academic Press, United Kingdom, pp. 1297-1303.

Tynan, F.E., Reid, H.H., Kjer-Nielsen, L., Miles, J.J., Wilce, M.C.J., Kostenko, L., Borg, N., Williamson, N.A., Beddoe, T.C., Purcell, A.W., Burrows, S.R., McCluskey, J., Rossjohn, J., 2007, A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule, Nature Immunology, vol 8, issue 3, Nature Publishing Group, New York NY USA, pp. 268-276.

Sullivan, L.C., Clements, C.S., Beddoe, T.C., Johnson, D., Hoare, H.L., Lin, J., Huyton, T., Hopkins, E.J., Reid, H.H., Wilce, M.C.J., Kabat, J., Borrego, F., Coligan, J.E., Rossjohn, J., Brooks, A., 2007, The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition, Immunity, vol 27, issue 6, Cell Press, Cambridge MA USA, pp. 900-911.

Kjer-Nielsen, L., Borg, N.A., Pellicci, D.G., Beddoe, T.C., Kostenko, L., Clements, C.S., Williamson, N.A., Smyth, M.J., Besra, G.S., Reid, H.H., Bharadwaj, M., Godfrey, D.I., Rossjohn, J., McCluskey, J., 2006, A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition, Journal of Experimental Medicine, vol 203, issue 3, Rockefeller University Press, New York USA, pp. 661-673.

Paton, A.W., Beddoe, T.C., Thorpe, C.M., Whisstock, J., Wilce, M.C.J., Rossjohn, J., Talbot, U.M., Paton, J.C., 2006, AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP, Nature, vol 443, issue 7111, Nature Publishing Group, London UK, pp. 548-552.

Ely, L.K., Beddoe, T.C., Clements, C.S., Matthews, J.M., Purcell, A.W., Kjer-Nielsen, L., McCluskey, J., Rossjohn, J., 2006, Disparate thermodynamics governing T cell receptor-MHC-1 interactions implicate extrinsic factors in guiding MHC restriction, Proceedings of the National Academy of Sciences of the United States of America, vol 103, issue 17, National Academy of Sciences, Washington USA, pp. 6641-6646.

Marland, Z., Beddoe, T.C., Zaker-Tabrizi, L., Lucet, I., Brammananth, R., Whisstock, J.C., Wilce, M.C.J., Coppel, R.L., Crellin, P.K., Rossjohn, J., 2006, Hijacking of a substrate-binding protein scaffold for use in mycobacterial cell wall biosynthesis, Journal of Molecular Biology, vol 359, issue 4, Academic Press Ltd Elsevier Science Ltd, London UK, pp. 983-997.

Hoare, H.L., Sullivan, L.C., Pietra, G., Clements, C.S., Lee, E.J., Ely, L.K., Beddoe, T.C., Falco, M., Kjer-Nielsen, L., Reid, H.H., McCluskey, J., Moretta, L., Rossjohn, J., Brooks, A.G., 2006, Structural basis for a major histocompatibility complex class Ib-restricted T cell response, Nature Immunology, vol 7, issue 3, Nature Publishing Group, New York USA, pp. 256-264.

Wilmann, P., Battad, J., Beddoe, T.C., Olsen, S., Dove, S., Devenish, R.J., Rossjohn, J., Prescott, M., 2006, The 2.0 A crystal structure of a pocilloporin at pH 3.5: The structural basis for the linkage between color transition and halide binding, Photochemistry & Photobiology, vol 82, issue 2, American Society for Photobiology, Augusta USA, pp. 359-366.

Wilmann, P.G., Battad, J., Beddoe, T.C., Olsen, S., Smith, S.C., Dove, S., Devenish, R.J., Rossjohn, J., Prescott, M., 2006, The 2.0 angstrom crystal structure of a pocilloporin at pH 3.5: The structural basis for the linkage between color transition and halide binding, Photochemistry & Photobiology, vol 82, issue 2, American Society for Photobiology, Augusta USA, pp. 359-366.

Bushell, S.R., Bottomley, S.P., Rossjohn, J., Beddoe, T.C., 2006, Tracking the unfolding pathway of a multirepeat protein via tryptophan scanning: Evidence of localized instability in the mitochondrial import receptor Tom70, The Journal of Biological Chemistry, vol 281, issue 34, American Society for Biochemistry and Molecular Biology, Inc, Bethesda USA, pp. 24345-24350.

Ely, L.K., Beddoe, T.C., Matthews, J.M., Kjer-Nielsen, L., McCluskey, J., Rossjohn, J., 2005, A new mode of recognition: an entropically favoured T-cell receptor, Febs Journal, vol 272, Blackwell Publishing, Oxford England, p. 253.

Bushell, S.R., Beddoe, T.C., Perugini, M.A., Bottomley, S.P., Rossjohn, J., 2005, A structural and functional characterization of Tom70: a receptor of the mitochondrial import machinery, Febs Journal, vol 272, Blackwell Publishing, Oxford England, p. 365.

Ely, L.K., Green, K.J., Beddoe, T.C., Clements, C.S., Miles, J.J., Bottomley, S.P., Zernich, D., Kjer-Nielsen, L., Purcell, A.W., McCluskey, J., Rossjohn, J., Burrows, S.R., 2005, Antagonism of antiviral and allogeneic activity of a human public ctl clonotype by a single altered peptide ligand: Implications for allograft rejection, Journal of Immunology, vol 174, issue 9, American Association of Immunologists, Bethesda USA, pp. 5593-5601.

Marland, Z., Beddoe, T.C., Zaker-Tabrizi, L., Coppel, R.L., Crellin, P., Rossjohn, J., 2005, Expression, purification, crystallization and preliminary X-ray diffraction analysis of an essential lipoprotein implicated in cell-wall biosynthesis in Mycobacteria, Acta Crystallographica, vol 61, issue 12, Blackwell Publishing, Oxford England, pp. 1081-1083.

Tynan, F.E., Borg, N., Miles, J.J., Beddoe, T.C., El-Hassen, D., Silins, S.L., van Zuylen, W.J., Purcell, A.W., Kjer-Nielsen, L., McCluskey, J., Burrows, S.R., Rossjohn, J., 2005, High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I: implications for T-Cell receptor engagement and T-cell immunodominance, Journal of Biological Chemistry, vol 280, issue 25, American Society for Biochemistry and Molecular Biology Inc., Bethesda USA, pp. 23900-23909.

Tynan, F.E., Burrows, S.R., Buckle, A.M., Clements, C.S., Borg, N.A., Miles, J.J., Beddoe, T.C., Whisstock, J.C., Wilce, M.C.J., Silins, S.L., Burrows, J.M., Kjer-Nielsen, L., Kostenko, L., Purcell, A.W., McCluskey, J., Rossjohn, J., 2005, T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide, Nature Immunology, vol 6, issue 11, Nature Publishing Group, New York USA, pp. 1114-1122.

Borg, N.A., Ely, L.K., Beddoe, T.C., Macdonald, W.A., Reid, H.H., Clements, C.S., Purcell, A.W., Kjer-Nielsen, L., Miles, J.J., Burrows, S.R., McCluskey, J., Rossjohn, J., 2005, The CDR3 regions of an Immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition, Nature Immunology, vol 6, issue 2, Nature Publishing Group, New York USA, pp. 171-180.

Law, R.H.P., Irving, J.A., Buckle, A.M., Ruzyla, K., Buzza, M.S., Bashtannyk-Puhalovich, T.A., Beddoe, T.C., Nguyen, K., Worrall, M.D., Bottomley, S.P., Bird, P.I., Rossjohn, J., Whisstock, J.C., 2005, The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix, Journal of Biological Chemistry, vol 280, issue 23, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 22356-22364.

Beddoe, T.C., Bushell, S.R., Perugini, M.A., Lithgow, T., Mulhern, T.D., Bottomley, S.P., Rossjohn, J., 2004, A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway, Journal of Biological Chemistry, vol 279, issue 45, The American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 46448-46454.

Kjer-Nielsen, L., Dunstone, M.A., Kostenko, L., Ely, L.K., Beddoe, T.C., Mifsud, N.A., Purcell, A.W., Brooks, A.G., McCluskey, J., Rossjohn, J., 2004, Crystal structure of the human T cell receptor CD3 heterodimer complexed to the therapeutic mAb OKT3, Proceeedings of the National Academy of Sciences of the United Stated of America, vol 101, issue 20, National Academy of Sciences, Washington USA, pp. 7675-7680.

Webb, A.I., Dunstone, M.A., Chen, W., Aguilar, M.I., Chen, Q., Jackson, H., Chang, L., Kjer-Nielsen, L., Beddoe, T.C., McCluskey, J., Rossjohn, J., Purcell, A.W., 2004, Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue, The Journal of Biological Chemistry, vol 279, issue 22, American Society for Biochemistry and Molecular Biology Inc., Bethesda USA, pp. 23438-23446.

Zernich, D., Purcell, A.W., Macdonald, W.A., Kjer-Nielsen, L., Ely, L.K., Laham, N., Crockford, T., Mifsud, N.A., Bharadwaj, M., Chang, L., Tait, B.D., Holdsworth, R., Brooks, A.G., Bottomley, S.P., Beddoe, T.C., Peh, C.A., Rossjohn, J., McCluskey, J., 2004, Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion, The Journal of Experimental Medicine, vol 200, issue 1, Rockerfeller University Press, New York USA, pp. 13-24.

Webb, A.I., Borg, N.A., Dunstone, M.A., Kjer-Nielsen, L., Beddoe, T.C., McCluskey, J., Carbone, F.R., Bottomley, S.P., Aguilar, M.I., Purcell, A.W., Rossjohn, J., 2004, The structure of H-2Kb and Kbm8 complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance, The Journal of Immunology, vol 173, issue 1, American Association of Immunologists, Bethesda USA, pp. 402-409.

Petersen, J., Wilmann, P.G., Beddoe, T.C., Oakley, A.J., Devenish, R.J., Prescott, M., Rossjohn, J., 2003, The 2.0- crystal structure of eqFP611, a far red fluorescent protein from the sea anemone Entacmaea quadricolor, Journal of Biological Chemistry, vol 278, issue 45, American Society for Biochemistry and Molecular Biology Inc., Bethesda USA, pp. 44626-44631.

Prescott, M., Ling, M., Beddoe, T.C., Oakley, A.J., Dove, S., Hoegh-Guldberg, O., Devenish, R.J., Rossjohn, J., 2003, The 2.2 crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation, Structure, vol 11, issue 3, Cell Press, Cambridge USA, pp. 275-284.

Clements, C.S., Reid, H.H., Beddoe, T.C., Tynan, F.E., Perugini, M., Johns, T.G., Bernard, C.C.A., Rossjohn, J., 2003, The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis, Proceedings of the National Academy of Sciences of the United States of America, vol 100, issue 19, National Academy of Sciences, Washington USA, pp. 11059-11064.

Beddoe, T.C., Ling, M., Dove, S., Hoegh-Guldberg, O., Devenish, R.J., Prescott, M., Rossjohn, J., 2003, The production, purification and crystallization of a pocilloporin pigment from a reef-forming coral, Acta Crystallography Section D-BIological Crystallography, vol 59, Blackwell Munksgaard, Copenhagen Denmark, pp. 597-599.

Beddoe, T.C., Lithgow, T.J., 2002, REVIEW: Delivery of nascent polypeptides to the mitochondrial surface, Biochimica et Biophysica Acta, vol 1592, issue 1, Elsevier BV, The Netherlands, pp. 35-39.

George, R., Walsh, P., Beddoe, T.C., Lithgow, T.J., 2002, The nascent polypeptide-associated complex (NAC) promotes interaction of ribosomes with the mitochondrial surface in vivo, FEBS Letters, vol 516, issue 1-3, Elsevier BV, The Netherlands & Denmark, pp. 213-216.

Gratzer, S., Beilharz, T., Beddoe, T.C., Henry, M.F., Lithgow, T.J., 2000, The mitochondrial protein targeting suppressor (mts1) mutation maps to the mRNA-binding domain of Npl3p and affects translation on cytoplasmic polysomes, Molecular Microbiology, vol 35, issue 6, Wiley-Blackwell Publishing Ltd, UK, pp. 1277-1285.

Conference Proceedings

Kjer-Nielsen, L., Beddoe, T.C., Kostenko, L., Clements, C.S., Williamson, N.A., Besra, G.S., Reid, H.H., Bharadwaj, M., Godfrey, D.I., McCluskey, J., Rossjohn, J., 2005, A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1D-mediated antigen recognition, Tissue Antigens, 29 November 2005 - 3rd December 2005, Blackwell Publishing, Oxford England, p. 365.

Tynan, F.E., Burrows, S.R., Buckle, A.M., Clements, C.S., Borg, N., Beddoe, T.C., Whisstock, J.C., Wilce, M.C.J., Silins, S.L., Burrows, J.M., Kjer-Nielsen, L., Kostenko, L., Purcell, A.W., McCluskey, J., Rossjohn, J., 2005, A super-bulged epitope and single amino acid polymorphism identify critical features for T cell recognition, Tissue Antigens, 29 November 2005 - 3rd December 2005, Blackwell Publishing, Oxford England, p. 571.

Hoare, H.L., Sullivan, L.C., Pietra, G., Clements, C.S., Beddoe, T.C., Kjer-Nielsen, L., Reid, H.H., McCluskey, J., Moretta, L., Rossjohn, J., 2005, Recognition of the non-classical MHC class I molecule, HLA-E, by the adaptive immune system, Tissue Antigens, 29 November 2005 - 3rd December 2005, Blackwell Publishing, Oxford England, p. 443.

Other

Pang, S.S., Berry, R., Chen, Z., Kjer-Nielsen, L., Perugini, M.A., King, G.F., Wang, C., Chew, S.H., La Gruta, N.L., Williams, N.K., Beddoe, T.C., Tiganis, T., Cowieson, N.P., Godfrey, D.I., Purcell, A.W., Wilce, M.C., McCluskey, J., Rossjohn, J., 2010, Crucial link in immune development and regulation unearthed, Quality control mechanism that must take place for our immune system, Monash University, Clayton, Vic, Australia.

Rossjohn, J., Beddoe, T.C., Dunstone, M.A., Ely, L.K., McCluskey, J., Kjer-Nielsen, L., Kostenko, L., Purcell, A.W., 2004, Crystal structure of CD3ϵgammaad;/OKT3 complex, Australia.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Structure function of mycolic acid biosynthesis in Mycobacterium tuberculosis.

Supervisors:

Rossjohn, J (Main), Beddoe, T (Associate).

Completed Supervision

Student:

Shahine, A.

Program of Study:

Protein crystallography for TB. 2009.

Supervisors:

Rossjohn, J (Main), Beddoe, T (Associate).