Prof Andrew Tonkin - Researcher Profile

Biography

• Head of Cardiovascular Research Unit - Department of Epidemiology and Preventive Medicine, Monash University.
• Consultant Cardiologist - Austin and Repatriation Medical Centre
• Member of the National Heart Stroke and Vascular Health Strategies Group.
• Chair of the Steering Committee for National CVD Monitoring System Data Working Group
• Chair of the National Cardiac Procedures Register Working Group
• Chair of a number of NHMRC and NHF/CSANZ evidence-based clinical guidelines committees.
• Member of the National Institute of Clinical Studies Heart Failure Advisory Group

Qualifications

M.D. MASTER IN MEDICINE (HYPERTENSION OF MUSCLES)

Institution: University of Melbourne

Year awarded: 1975

FRACP FELLOWSHIP

Institution: FRACP Fellowship

Year awarded: 1975

M.R.A.C.P. FELLOWSHIP

Institution: M.R.A.C.P. Fellowship

Year awarded: 1971

MBBS: BACHELOR OF MEDICINE & SURGERY

Institution: University of Melbourne

Year awarded: 1967

Publications

Books

Tonkin, A.M. (ed), 2009, Therapeutic Strategies in Lipid Disorders, Clinical Publishing, Oxford, UK.

Tonkin, A.M. (ed), 2003, Atherosclerosis and Heart Disease, Martin Dunitz, United Kingdom.

Book Chapters

Chen, L., Tonkin, A.M., 2009, Absolute risk assessment in the general population, in Therapeutic Strategies in Lipid Disorders, eds A.M. Tonkin, Clinical Publishing, Oxford, UK, pp. 155-176.

Haas, S.J., Thien, F., Tonkin, A.M., Kong, D.C.M., Nelson, M.R., Demos, L.L., Zimmet, H.S., Krum, H., Liew, D.Y.H., McNeil, J.J., 2009, Clozapine-associated myocarditis and cardiomyopathy - It's the heart that is important, not the classification, in Cardiomyopathies, Effects and Treatments, eds Peter H. Bruno & Matthew T. Giordano, Nova Science Publishers, New York, pp. 251-283.

Tonkin, A.M., 2009, The enhanced evidence base and translation into improved outcomes, in Therapeutic Strategies in Lipid Disorders, eds A.M. Tonkin, Clinical Publishing, Oxford, UK, pp. 245-261.

Stewart, J.I., Washbrook, E., Tonkin, A.M., 2008, Moderate- to low-risk patients: Management recommendations, in Cardiovascular Risk Management, eds F D Richard Hobbs and Bruce Arroll, John Wiley & Sons, UK, pp. 28-33.

Tonkin, A.M., Chen, L., 2007, Lipid-modifying therapy in a person with diabetes and an acute coronary syndrome, in Case Studies in Lipid Management, eds D John Betteridge, Informa Healthcare, United Kingdom, pp. 29-33.

Tonkin, A.M., 2003, Future challenges, in Atherosclerosis and Heart Disease, eds Andrew Tonkin, Martin Dunitz, United Kingdom, pp. 215-224.

Journal Articles

Ronaldson, K.J., Lam, L.L.Y., Rodrigo, S., Tonkin, A.M., 2012, A meta-analysis of haemorrhage with ticlopidine and clopidogrel following coronary artery stent placement, European Journal of Cardiovascular Medicine [E], vol 11, issue 11, Healthcare Bulletin, United Kingdom, pp. 98-104.

Watts, G.F., Sullivan, D., van Bockxmeer, F.M., Poplawski, N., Hamilton-Craig, I., George, P.M., O'Brien, R.C., Bishop, W., George, P.M., Semsarian, C., Tonkin, A.M., 2012, A new model of care for familial hypercholesterolaemia: what is the role of cardiology?, Heart Lung and Circulation [P], vol 21, issue 9, Elsevier Australia, Australia, pp. 543-550.

Nelson, M., Ramsay, E., Ryan, P., Willson, K., Tonkin, A.M., Wing, L.M., Simons, L., Reid, C.M., 2012, A score for the prediction of cardiovascular events in the hypertensive aged, American Journal of Hypertension [P], vol 25, issue 2, Nature Publishing Group, United States, pp. 190-194.

Clark, R., Coffee, N., Turner, D., Eckert, K., Gaans, D., Wilkinson, D., Stewart, S., Tonkin, A., 2012, Application of geographic modelling techniques to quantify spatial access to health services before and after an acute cardiac event: the cardiac ARIA project, Circulation [P], vol 125, issue 16, Lippincott Williams & Wilkins, United States, pp. 2006-2014.

Reid, C.M., Storey, E., Wong, T.Y., Woods, R.L., Tonkin, A.M., Wang, J.J., Kam, A., Janke, A., Essex, R., Abhayaratna, W., Budge, M., 2012, Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion), BMC Neurology [P], vol 12, issue 3, BioMed Central Ltd, UK, pp. 1-9.

Reid, C., Storey, E., Wong, T., Woods, R., Tonkin, A., Wang, J., KAM, A., Janke, A., Essex, R., Abhayaratna, W., Budge, M., 2012, Aspiring for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion), BMC Neurology [P], vol 12, issue 3, Biomed Central Ltd, England, pp. 1-9.

Boekholdt, S., Arsenault, B., Mora, S., Pederson, T., LaRosa, J., Nestel, P., Simes, J., Durrington, P., Hitman, G., Welsh, K., DeMicco, D., Zwinderman, A., Clearfield, M., Downs, J., Tonkin, A., Colhoun, H., Gotto, A., Ridker, P., Kastelein, J., 2012, Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis, Jama-Journal Of The American Medical Association [P], vol 307, issue 12, American Medical Association, United States, pp. 1302-1309.

Roberts, M.A., Pilmore, H., Tonkin, A.M., Garg, A.X., Pascoe, E., Badve, S.V., Cass, A., Lerino, F.L., Hawley, C.M., 2012, Challenges in blood pressure measurement in patients treated with maintenance hemodialysis, American Journal Of Kidney Diseases [P], vol 60, issue 3, W.B. Saunders Co., United States, pp. 463-472.

Ranasinghe, I., Turnbull, F., Tonkin, A.M., Clark, R.A., Coffee, N., Brieger, D., 2012, Comparative effectiveness of population interventions to improve access to reperfusion for ST-segment-elevation myocardial infarction in Australia, Circulation: Cardiovascular Quality and Outcomes [P], vol 5, issue 4, Lippincott Williams & Wilkins, United States, pp. 429-436.

Tonkin, A., Hunt, D., Voysey, M., Kesaniemi, Y., Hamer, A., Waites, J., Mahar, L., Mann, S., Glasziou, P., Forder, P., Simes, J., Keech, A., 2012, Effects of fenofibrate on cardiovascular events in patients with diabetes, with and without prior cardiovascular disease: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study, Diabetes and Metabolism [P], vol 163, issue 3, Elsevier Masson, France, pp. 508-514.

Linden, M., Tran, H.A., Woods, R.L., Tonkin, A.M., 2012, High platelet reactivity and antiplatelet therapy resistance, Seminars In Thrombosis And Hemostasis [P], vol 38, issue 2, Thieme Medical Publishing Co, United States, pp. 200-212.

Kiropoulos, L.A., Meredith, I.T., Tonkin, A.M., Clarke, D.M., Antonis, P., Plunkett, J.C., 2012, Increased psychosocial stress in Greek-born immigrants compared to Anglo-Australians with coronary heart disease: the healthy heart, healthy mind study, Heart Lung and Circulation [P], vol 21, issue 12, Elsevier Australia, Australia, pp. 794-802.

Coffee, N., Turner, D., Clark, R., Eckert, K., Coombe, D., Hugo, G., Gaans, D., Wilkinson, D., Stewart, S., Tonkin, A., 2012, Measuring national accessibility to cardiac services using geographic information systems, Applied Geography [P], vol 34, Pergamon, United Kingdom, pp. 445-455.

Driscoll, A., Currey, J., Tonkin, A.M., Krum, H., 2012, Nurse-led titration of angiotensin converting enzyme inhibitors, beta-adrenergic blocking agents and angiotensin receptor blockers for patients with left ventricular systolic dysfunction (Protocol), Cochrane Database of Systematic Reviews [P], vol 6, issue Art. ID: CD009889, John Wiley & Sons Ltd, United Kingdom, pp. 1-9.

Kiropoulos, L.A., Meredith, I.T., Tonkin, A.M., Clarke, D.M., Antonis, P., Plunkett, J.C., 2012, Psychometric properties of the cardiac depression scale in patients with coronary heart disease, BMC Psychiatry [P], vol 12, issue Art. No.: 216, BioMed Central Ltd, United Kingdom, pp. 1-8.

Krum, H., Forbes, A.B., Yallop, J.J., Driscoll, A., Croucher, J.L., Chan, B.G.Y., Clark, R., Davidson, P., Huynh, L., Kasper, E.K., Hunt, D., Egan, H., Stewart, S., Piterman, L., Tonkin, A.M., 2012, Telephone support to rural and remote patients with heart failure: the Chronic Heart failure Assessment by Telephone (CHAT) study, Cardiovascular Therapeutics [P], vol epub, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 1-32.

Harriss, L., Ajani, A., Hunt, D., Shaw, J., Chambers, B., Dewey, H., Frayne, J., Beauchamp, A., Duve, K., Giles, G., Harrap, S., Magliano, D., Liew, D., McNeil, J., Peeters, A., Stebbing, M., Wolfe, R., Tonkin, A., 2011, Accuracy of national mortality codes in identifying adjudicated cardiovascular deaths, Australian and New Zealand Journal of Public Health [P], vol 35, issue 5, Wiley-Blackwell Publishing Asia, Australia, pp. 466-476.

Peeters, A., Nusselder, W., Stevenson, C., Boyko, E., Moon, L., Tonkin, A., 2011, Age-specific trends in cardiovascular mortality rates in the Netherlands between 1980 and 2009, European Journal Of Epidemiology [P], vol 26, issue 5, Springer Netherlands, Netherlands, pp. 369-373.

Astley, C., Tonkin, A., Mahar, L., Davidson, P., Boyden, A., Brieger, D., Pradhan, M., George, M., Mattschoss, S., Chew, D., 2011, Clinical effectiveness in everyday practice: improving outcomes for all patients through a national acute coronary syndrome data collaborative, Internal Medicine Journal [P], vol 41, Wiley-Blackwell Publishing Asia, Australia, pp. 206-210.

Driscoll, A., Tonkin, A., Stewart, A., Thompson, D., Worrall-Carter, L., Riegel, B., Hare, D., Davidson, P., Stewart, S., 2011, Development of an evidence-based scoring system (HF-IS) to assess the quality of heart failure programmes for patients postdischarge from hospital, Journal Of Clinical Nursing [P], vol 20, issue 21-22, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 3011-3019.

Briffa, T., Nedkoff, L., Peeters, A., Tonkin, A., Hung, J., Ridout, S., Knuiman, M., 2011, Discordant age and sex-specific trends in the incidence of a first coronary heart disease event in Western Australia from 1996 to 2007, Heart [P], vol 97, issue 5, B M J Group, United Kingdom, pp. 400-404.

Badve, S., Roberts, M., Hawley, C., Cass, A., Garg, A., Krum, H., Tonkin, A., Perkovic, V., 2011, Effects of beta-adrenergic antagonists in patients with chronic kidney disease: A systematic review and meta-analysis, Journal of the American College of Cardiology [P], vol 58, issue 11, Elsevier Inc., United States, pp. 1152-1161.

Beauchamp, A., Wolfe, R.S.J., Magliano, D.J., Turrell, G., Tonkin, A.M., Shaw, J.E., Peeters, A., 2011, Incidence of cardiovascular risk factors by education level 2000-2005: The Australian diabetes, obesity, and lifestyle (AusDiab) cohort study, Longitudinal and Life Course Studies [E], vol 2, issue 3, Society for Longitudinal and Life Course Studies, UK, pp. 331-345.

Chen, L., Magliano, D., Balkau, B., Wolfe, R., Brown, L., Tonkin, A., Zimmet, P., Shaw, J., 2011, Maximizing efficiency and cost-effectiveness of Type 2 diabetes screening: The AusDiab study, Diabetic Medicine [P], vol 28, issue 4, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 414-423.

Driscoll, A., Krum, H., Wolfe, R., Tonkin, A., 2011, Nurse-led titration of beta-adrenoreceptor blocking agents in chronic heart failure patients in the community, Journal Of Cardiac Failure [P], vol 17, issue 3, Churchill Livingstone, United States, pp. 224-230.

Briffa, T., Hobbs, M., Tonkin, A., Sanfilippo, F., Hickling, S., Ridout, S., Knuiman, M., 2011, Population trends of recurrent coronary heart disease event rates remain high, Circulation: Cardiovascular Quality and Outcomes [P], vol 4, issue 1, Lippincott Williams & Wilkins, United States, pp. 107-113.

Driscoll, A., Beauchamp, A., Lyubomirsky, G., Demos, L., McNeil, J., Tonkin, A., 2011, Suboptimal management of cardiovascular risk factors in coronary heart disease patients in primary care occurs particularly in women, Internal Medicine Journal [P], vol 41, issue 10, Wiley-Blackwell Publishing Asia, Australia, pp. 730-736.

Beauchamp, A., Tonkin, A., Kelsall, H., Sundararajan, V., English, D., Sundaresan, L., Wolfe, R., Turrell, G., Giles, G., Peeters, A., 2011, Validation of de-identified record linkage to ascertain hospital admissions in a cohort study, BMC Medical Research Methodology [P], vol 11, issue Art. No: 42, BioMed Central Ltd, United Kingdom, pp. 1-8.

Chen, L., Magliano, D.J., Balkau, B., Colagiuri, S., Zimmet, P.Z., Tonkin, A.M., Mitchell, P., Phillips, P., Shaw, J., 2010, AUSDRISK: an Australian Type 2 Diabetes Risk Assessment Tool based on demographic, lifestyle and simple anthropometric measures, Medical Journal Of Australia [P], vol 192, issue 4, Australasian Medical Publishing Company Pty. Ltd, Australia, pp. 197-202.

Hill, S., Spink, J., Cadilhac, D., Edwards, A., Kaufman, C., Rogers, S., Ryan, R., Tonkin, A., 2010, Absolute risk representation in cardiovascular disease prevention: Comprehension and preferences of health care consumers and general practitioners involved in a focus group study, BMC Public Health [P], vol 10, issue Art. No: 108, BioMed Central Ltd, United Kingdom, pp. 1-13.

Beauchamp, A., Tonkin, A., Peeters, A., Wolfe, R., Turrell, G., Harriss, L., Giles, G., English, D., Jenkins, A., 2010, Associations among smoking status, lifestyle and lipoprotein subclasses, Journal of Clinical Lipidology [P], vol 4, issue 6, Elsevier Inc., United States, pp. 522-530.

Beauchamp, A., Peeters, A., Tonkin, A., Turrell, G., 2010, Best practice for prevention and treatment of cardiovascular disease through an equity lens: A review, European Journal Of Cardiovascular Prevention & Rehabilitation [P], vol 17, issue 5, Sage Publications Ltd, United Kingdom, France, pp. 599-606.

Beauchamp, A.J., Peeters, A., Tonkin, A.M., Turrell, G., 2010, Best practice for prevention and treatment of cardiovascular disease through an equity lens: a review, European Journal Of Cardiovascular Prevention & Rehabilitation [P], vol 17, issue 5, Sage Publications, UK, pp. 599-606.

Brown, A., Brieger, D., Tonkin, A.M., White, H., Walsh, W., Ridell, T., Zeitz, C.J., Jeremy, R., Kritharides, L., 2010, Coronary Disease in Indigenous Populations: Summary from the CSANZ Indigenous Cardiovascular Health Conference, Heart Lung and Circulation [P], vol 19, issue 5-6, Elsevier Australia, Australia, pp. 299-305.

Cameron, A., Sicree, R., Zimmet, P., Alberti, K., Tonkin, A., Balkau, B., Tuomilehto, J., Chitson, P., Shaw, J., 2010, Cut-points for waist circumference in Europids and South Asians, Obesity [P], vol 18, issue 10, Nature Publishing Group, United States, pp. 2039-2046.

Tonkin, A.M., Chen, L., 2010, Effects of combination lipid therapy in the management of patients with type 2 diabetes mellitus in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, Circulation [P], vol 122, issue 8, Lippincott Williams & Wilkins, United States, pp. 850-852.

Baigent, C., Blackwell, L., Emberson, J., Holland, L.E., Reith, C., Bhala, N., Peto, R., Barnes, E., Keech, A., Simes, J., Collins, R., Tonkin, A., 2010, Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170,000 participants in 26 randomised trials, Lancet [P], vol 376, issue 9753, The Lancet Publishing Group, United Kingdom, pp. 1670-1681.

Barr, E.L., Cameron, A.J., Balkau, B., Zimmet, P.Z., Welborn, T.A., Tonkin, A.M., Shaw, J.E., 2010, HOMA insulin sensitivity index and the risk of all-cause mortality and cardiovascular disease events in the general population: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab) study, Diabetologia [P], vol 53, issue 1, Springer, Germany, pp. 79-88.

Jeremy, R., Tonkin, A.M., White, H., Ridell, T., Brieger, D., Walsh, W., Zeitz, C.J., Brown, A., Kritharides, L., 2010, Improving cardiovascular care for indigenous populations, Heart Lung and Circulation [P], vol 19, issue 5-6, Elsevier Australia, Australia, pp. 344-350.

Beauchamp, A., Peeters, A., Wolfe, R., Turrell, G., Harriss, L., Giles, G., English, D., McNeil, J., Magliano, D., Harrap, S., Liew, D., Hunt, D., Tonkin, A., 2010, Inequalities in cardiovascular disease mortality: The role of behavioural, physiological and social risk factors, Journal of epidemiology and community health [P], vol 64, issue 6, BMJ Group, United Kingdom, Spain, pp. 542-548.

Dennekamp, M., Akram, M., Abramson, M., Tonkin, A., Sim, M., Fridman, M., Erbas, B., 2010, Outdoor air pollution as a trigger for out-of-hospital cardiac arrests, Epidemiology [P], vol 21, issue 4, Lippincott Williams & Wilkins, United States, pp. 494-500.

Kritharides, L., Brown, A., Brieger, D., Ridell, T., Zeitz, C.J., Jeremy, R., Tonkin, A.M., Walsh, W., White, H., 2010, Overview and determinants of cardiovascular disease in indigenous populations, Heart Lung and Circulation [P], vol 19, issue 5-6, Elsevier Australia, Australia, pp. 337-343.

Nelson, M., Ryan, P., Tonkin, A., Ramsay, E., Willson, K., Wing, L., Reid, C.M., 2010, Pred/iction of cardiovascular events in subjects in the second australian national blood pressure study, Hypertension [P], vol 56, issue 1, Lippincott Williams & Wilkins, United States, pp. 44-48.

Mark, D.B., Anstrom, K., McNulty, S., Flaker, G., Tonkin, A.M., Smith, W.M., Toff, W.D., Dorian, P., Clapp-Channing, N.E., Anderson, J., Johnson, G., Schron, E.B., Poole, J.E., Lee, K.L., Bardy, G.H., 2010, Quality of life effects of automatic external defibrillators in the home: Results from the Home Automatic External Defibrillator Trial (HAT), American Heart Journal [P], vol 159, issue 4, Mosby Inc., United States, pp. 627-634.e7.

Liu, H., Patel, A., Brown, A., Eades, S., Hayman, N., Jan, S., Ring, I., Stewart, G., Tonkin, A.M., Weeramanthri, T., Wade, V., Rodgers, A., Usherwood, T., Neal, B., Peiris, D., Burke, H., Reid, C.M., Cass, A., 2010, Rationale and design of the Kanyini guidelines adherence with the polypill (Kanyini-GAP) study: A randomised controlled trial of a polypill-based strategy amongst Indigenous and non Indigenous people at high cardiovascular risk, BMC Public Health [P], vol 10, issue Art. No. 458, BioMed Central Ltd, United Kingdom, pp. 1-8.

Kritharides, L., Brown, A., Brieger, D., Ridell, T., Zeitz, C.J., Jeremy, R., Tonkin, A.M., Walsh, W., White, H., 2010, Recommendations arising from the inaugural CSANZ Conference on Indigenous Cardiovascular Health, Heart Lung and Circulation [P], vol 19, issue 5-6, Elsevier Australia, Australia, pp. 269-272.

White, H., Walsh, W., Brown, A., Ridell, T., Tonkin, A.M., Jeremy, R., Brieger, D., Zeitz, C.J., Kritharides, L., 2010, Rheumatic heart disease in indigenous populations, Heart Lung and Circulation [P], vol 19, issue 5-6, Elsevier Australia, Australia, pp. 273-281.

Cui, J.J., Forbes, A.B., Kirby, A., Marschner, I., Simes, J., Hunt, D.J., West, M.J., Tonkin, A.M., 2010, Semi-parametric risk prediction models for recurrent cardiovascular events in the LIPID study, BMC Medical Research Methodology [P], vol 10, issue Art. No. 27, BioMed Central Ltd, United Kingdom, pp. 1-9.

Brown, A., Tonkin, A.M., White, H., Ridell, T., Brieger, D., Walsh, W., Zeitz, C.J., Jeremy, R., Kritharides, L., 2010, The Cardiac Society Inaugural Cardiovascular Health Conference. Conference Findings and Ways Forward., Heart Lung and Circulation [P], vol 19, issue 5-6, Elsevier Australia, Australia, pp. 264-268.

Rostambeigi, N., Shaw, J., Atkins, R.C., Ghanbarian, A., Cameron, A., Forbes, A.B., Momenan, A., Hadaegh, F., Mirmiran, P., Zimmet, P.Z., Azizi, F., Tonkin, A.M., 2010, Waist circumference has heterogeneous impact on development of diabetes in different populations: Longitudinal comparative study between Australia and Iran, Diabetes Research and Clinical Practice [P], vol 88, issue 1, Elsevier Ireland Ltd, Ireland, Belgium, pp. 117-124.

Ashton, E., Windebank, E., Skiba, M., Reid, C., Schneider, H., Rosenfeldt, F., Tonkin, A., Krum, H., 2010, Why did high-dose rosuvastatin not improve cardiac remodeling in chronic heart failure? Mechanistic insights from the UNIVERSE study, International Journal of Cardiology [P], vol 146, issue 3, Elsevier Ireland Ltd, Ireland, pp. 404-407.

Barr, E.L.M., Boyko, E.J., Zimmet, P.Z., Wolfe, R.S.J., Tonkin, A.M., Shaw, J.E., 2009, Continuous relationships between non-diabetic hyperglycaemia and both cardiovascular disease and all-cause mortality: The Australian Diabetes, Obesity, and Lifestyle (AusDiab) study, Acta Diabetologica [P], vol 52, issue 3, Springer Italia Srl, Italy, pp. 415-424.

Driscoll, A., Worrall-Carter, L., Hare, D., Davidson, P., Riegel, B., Tonkin, A.M., Stewart, S., 2009, Evidence-based chronic heart failure management programs: reality or myth?, Quality and Safety in Health Care [P], vol 18, issue 6, BMJ Publishing Group, England, pp. 450-455.

Driscoll, A., Worrall-Carter, L., Hare, D., Davidson, P., Riegel, B., Tonkin, A., Stewart, S., 2009, Eviidence-based chronic heart-failure management programmes: reality or myth?, BMJ Quality & Safety [P], vol 18, issue 6, B M J Group, United Kingdom, pp. 450-455.

Cameron, A., Dunstan, D.W., Neville, O., Zimmet, P.Z., Barr, E.L., Tonkin, A.M., Magliano, D.J., Murray, S.G., Welborn, T.A., Shaw, J.E., 2009, Health and mortality consequences of abdominal obesity: evidence from the AusDiab study, Medical Journal Of Australia [P], vol 191, issue 4, Australasian Medical Publishing Company Pty Ltd, Australia, pp. 202-208.

Woods, R.L., Nelson, M., Tonkin, A.M., Reid, C.M., 2009, In reply: Should aspirin be used for the primary prevention of cardiovascular disease in people with diabetes?, Medical Journal Of Australia [P], vol 191, issue 6, Australasian Medical Publishing Company Pty. Ltd, Australia, pp. 356-357.

Cui, J.J., Forbes, A.B., Kirby, A., Simes, J., Tonkin, A.M., 2009, Laboratory and non-laboratory-based risk prediction models for secondary prevention of cardiovascular disease: the LIPID study, European Journal Of Cardiovascular Prevention & Reh..., vol 16, issue 6, Lippincott Williams & Wilkins, United States, France, pp. 660-668.

Soderberg, S., Colquhoun, D., Keech, A., Yallop, J.J., Barnes, E., Pollicino, C., Simes, J., Tonkin, A.M., Nestel, P.J., 2009, Leptin, but not adiponectin, is a predictor of recurrent cardiovascular events in men: results from the LIPID study, International Journal Of Obesity [P], vol 33, Nature Publishing Group, United Kingdom, pp. 123-130.

Tonkin, A.M., Boyden, A., Colagiuri, S., 2009, Maximising the effectiveness and cost-effectiveness of cardiovascular disease prevention in the general population, Medical Journal Of Australia [P], vol 191, issue 6, Australasian Medical Publishing Company Pty Ltd, Australia, pp. 300-302.

Chen, L., Tonkin, A.M., Moon, L., Mitchell, P., Dobson, A., Giles, G., Hobbs, M., Phillips, P.J., Shaw, J.E., Simmons, D., Simons, L.A., Fitzgerald, A.P., De Backer, G., de Bacquer, D., 2009, Recalibration and validation of the SCORE risk chart in the Australian population: the AusSCORE chart, European Journal Of Cardiovascular Prevention & Rehabilitation [P], vol 16, Lippincott Williams & Wilkins, United States, France, pp. 562-570.

Woods, R.L., Tonkin, A.M., Nelson, M., Britt, H., Reid, C.M., 2009, Should aspirin be used for the primary prevention of cardiovascular disease in people with diabetes?, Medical Journal Of Australia [P], vol 190, issue 11, Australasian Medical Publishing Company Pty. Ltd, Australia, pp. 614-615.

Tonkin, A.M., Forbes, A.B., Haas, S.J., 2009, The evidence on trial: cholesterol lowering and cancer, Heart Asia [E], vol E, issue 2, BMJ, UK, pp. 6-10.

Tonkin, A.M., Beauchamp, A.J., Stevenson, C.E., 2009, The importance of extinguishing secondhand smoke, Circulation [P], vol 120, Lippincott Williams & Wilkins, United States, pp. 1339-1341.

Barr, E.L., Tonkin, A.M., Welborn, T.A., Shaw, J., 2009, Validity of self-reported cardiovascular disease events in comparison to medical record adjudication and a statewide hospital morbidity database: The AusDiab study, Internal Medicine Journal [P], vol 39, Wiley-Blackwell Publishing Asia, Australia, pp. 49-53.

Tonkin, A.M., Chen, L., 2009, Where on the healthcare continuum should we invest? The case for primary care?, Heart Lung and Circulation [P], vol 18, issue 2, Elsevier Australia, Australia, pp. 108-113.

Myles, P.S., Smith, J.A., Knight, J., Cooper, D.J., Silbert, B., McNeil, J.J., Esmore, D.S., Buxton, B.F., Krum, H., Forbes, A.B., Tonkin, A.M., 2008, Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) Trial: Rationale and design, American Heart Journal, vol 155, issue 2, Mosby, Inc., United States, pp. 224-230.

Stewart, R.A., North, F.M., Sharples, K.J., Simes, J., Tonkin, A.M., White, H., 2008, Differences in cardiovascular mortality between Australia and New Zealand according to socioeconomic status: Findings from the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study, The New Zealand Medical Journal, vol 121, issue 1269, New Zealand Medical Association, New Zealand, pp. 11-23.

Kearney, P.M., Blackwell, L., Collins, R., Keech, A., Simes, J., Peto, R., Armitage, J., Baigent, C., Downs, J.R., Gotto, A., Clearfield, M., Holdaas, H., Tonkin, A.M., Varigos, J.D., 2008, Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis, The Lancet, vol 371, issue 9607, The Lancet Publishing Group, United Kingdom, pp. 117-125.

Nelson, M., Reid, C.M., Ames, D.A., Beilin, L.J., Donnan, G.A., Gibbs, P., Johnston, C.I., Krum, H., Storey, E., Tonkin, A.M., Wolfe, R.S.J., Woods, R.L., McNeil, J.J., 2008, Feasibility of conducting a primary prevention trial of low-dose aspirin for major adverse cardiovascular events in older people in Australia: Results from the ASPirin in Reducing Events in the Elderly (ASPREE) pilot study, Medical Journal of Australia, vol 189, issue 2, Australasian Medical Publishing Company Pty. Ltd., Australia, pp. 105-109.

Bardy, G.H., Lee, K.L., Mark, D.B., Poole, J.E., Toff, W.D., Tonkin, A.M., Smith, W., Dorian, P., Packer, D.L., White, R.D., Longstreth, W., Anderson, J., Johnson, G., Bischoff, E., Yallop, J.J., McNulty, S., Davidson Ray, L., Clapp-Channing, N.E., Rosenberg, Y., Schron, E.B., 2008, Home use of automated external defibrillators for sudden cardiac arrest, New England Journal of Medicine, vol 358, issue 17, Massachusetts Medical Society, United States, pp. 1793-1804.

Chen, L., Rogers, S.L., Colagiuri, S., Cadilhac, A.D., Mathew, H.T., Boyden, A., Peeters, A., Magliano, D.J., Shaw, J., Zimmet, P.Z., Tonkin, A.M., 2008, How do the Australian guidelines for lipid-lowering drugs perform in practice? Cardiovascular disease risk in the AusDiab Study, 1999-2000, Medical Journal of Australia, vol 189, issue 6, Australasian Medical Publishing Company Pty Ltd, Australia, pp. 319-322.

Glasziou, P.P., Irwig, L., Heritier, S.R., Simes, J., Tonkin, A.M., 2008, Monitoring cholesterol levels: Measurement error or true change?, Annals of Internal Medicine, vol 148, issue 9, American College of Physicians, United States, pp. 656-661.

Cui, J.J., Forbes, A.B., Kirby, A., Marschner, I., Simes, J., West, M.J., Tonkin, A.M., 2008, Parametric conditional frailty models for recurrent cardiovascular events in the lipid study., Clinical Trials, vol 5, Sage Science Press (UK), United Kingdom, United States, pp. 565-574.

Cannon, C., Giugliano, R.P., Blazing, M.A., Harrington, R.A., Peterson, J.L., Sisk, C.M., Strony, J., Musliner, T.A., McCabe, C.H., Veltri, E., Braunwald, E., Califf, R.M., Tonkin, A.M., 2008, Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): Comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes, American Heart Journal, vol 156, issue 5, Mosby, Inc., United States, pp. 826-832.

Bardy, G.H., Lee, K.L., Mark, D.B., Poole, J.E., Toff, W.D., Tonkin, A.M., Smith, W., Dorian, P., Yallop, J.J., Packer, D.L., White, R.D., Longstreth, W., Anderson, J., Johnson, G., Bischoff, E., Munkers, C.D., Brown, A., McNulty, S., Davidson Ray, L., Clapp-Channing, N.E., Rosenberg, Y., Salive, M., Schron, E.B., 2008, Rationale and design of the Home Automatic External Defibrillator Trial (HAT), American Heart Journal, vol 155, issue 3, Mosby, Inc., United States, pp. 445-454.

Cameron, A.J., Magliano, D.J., Zimmet, P.Z., Welborn, T.A., Colagiuri, S., Tonkin, A.M., Shaw, J., 2008, The metabolic syndrome as a tool for predicting future diabetes: the AusDiab study, Journal of Internal Medicine, vol 264, issue 2, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 177-186.

West, M.J., Nestel, P.J., Kirby, A., Schnabel, R., Sullivan, D., Simes, J., Pollicino, C., Lubos, E., Munzel, T.F., White, H., Tonkin, A.M., Bickel, C., Tiret, L., Blankenberg, S., 2008, The value of N-terminal fragment of brain natriuretic peptide and tissue inhibitor of metalloproteinase-1 levels as predictors of cardiovascular outcome in the LIPID study, European Heart Journal, vol 29, issue 7, Oxford University Press, United Kingdom, France, pp. 923-931.

Clark, R., Yallop, J.J., Piterman, L., Croucher, J.L., Tonkin, A.M., Stewart, S., Krum, H., 2007, Adherence, adaptation and acceptance of elderly chronic heart failure patients to receiving healthcare via telephone-monitoring, The European Journal of Heart Failure, vol 9, issue 11, Elzevier Science BV, The Netherlands, pp. 1104-1111.

Harriss, L.R., English, D., Hopper, J.L., Powles, J., Simpson, J.A., O'Dea, K., Giles, G.G., Tonkin, A.M., 2007, Alcohol consumption and cardiovascular mortality accounting for possible misclassification of intake: 11-year follow-up of the Melbourne Collaborative Cohort Study, Addiction, vol 102, issue 10, Wiley-Blackwell Publishing Ltd, UK, pp. 1574-1585.

Chen, L., Peeters, A., Magliano, D.J., Shaw, J.E., Welborn, T.A., Wolfe, R.S.J., Zimmet, P.Z., Tonkin, A.M., 2007, Anthropometric measures and absolute cardiovascular risk estimates in the Australian Diabetes, Obesity and Lifestyle (AusDiab) Study, The European Society of Cardiology, vol 14, issue 6, Lippincott Williams & Wilkins, USA, pp. 740-745.

Haas, S.J., Hill, R., Krum, H., Liew, D.Y.H., Tonkin, A.M., Ioannides-Demos, L.L., Stephan, K.L., McNeil, J.J., 2007, Clozapine-associated myocarditis: A review of 116 cases of suspected myocarditis associated with the use of clozapine in Australia during 1993-2003, Drug Safety, vol 30, issue 1, Adis International Ltd, New Zealand, pp. 47-57.

Harriss, L.R., English, D., Powles, J., Giles, G., Tonkin, A.M., Hodge, A.M., Brazionis, L., O'Dea, K., 2007, Dietary patterns and cardiovascular mortality in the Melbourne Collaborative Cohort Study, American Journal of Clinical Nutrition: a journal reporting the practical application of our world-wide knowledge of nutrition, vol 86, issue 1, American Society for Nutrition, USA, pp. 221-229.

Krum, H., Ashton, E.L., Reid, C.M., Kalff, V., Rogers, J., Amarena, J., Singh, B., Tonkin, A.M., 2007, Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure, Journal of Cardiac Failure, vol 13, issue 1, Churchill Livingstone, USA, pp. 1-7.

Chen, L., Tonkin, A.M., 2007, Meta-analysis of the effect of thiazolidinediones on in-stent restenosis after coronary stant implantation, American Heart Journal, vol 154, issue 5, Mosby Inc, United States, p. e41.

Barr, E.L., Zimmet, P.Z., Wellborn, T., Jolley, D.J., Magliano, D.J., Dunstan, D.W., Cameron, A.J., Dwyer, T., Taylor, H.R., Tonkin, A.M., Wong, T.Y., McNeil, J.J., Shaw, J.E., 2007, Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus, impaired fasting glucose, and impaired glucose tolerance: The Australian Diabetes, Obesity, and Lifestyle Study (AusDiab), Circulation, vol 116, issue 2, Lippincott Wilkins & Wilkins, USA, pp. 151-157.

Clark, R.A., Eckert, K.A., Stewart, S., Phillips, S.M., Yallop, J.J., Tonkin, A.M., Krum, H., 2007, Rural and urban differentials in primary care management of chronic heart failure: new data from the CASE study, Medical Journal of Australia, vol 186, issue 9, Australasian Medical Publishing Company Pty Ltd, Australia, pp. 441-445.

Barter, P.J., Ballantyne, C.M., Carmena, R., Cabezas, M.C., Chapman, M.J., Couture, P., Graaf, J.D., Durrington, P.N., Faergeman, O., Frohlich, J., Furberg, C., Gagne, C., Haffner, S.M., Humphries, S.E., Jungner, I., Krauss, R.M., Kwiterovitch, P., Marcovina, S., Packard, C., Pearson, T.A., Reddy, K.S., Rosenson, R., Sarrafzadegan, N., Sniderman, A.D., Stalenhoef, A.F., Stein, E., Talmud, P.J., Tonkin, A.M., Walldius, G., Williams, K.M.S., 2006, Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel, Journal of Internal Medicine, vol 259, issue 3, Blackwell Publishing Ltd, UK, pp. 247-258.

Tapp, R., Dunstan, D.W., Phillips, P., Tonkin, A.M., Zimmet, P.Z., Shaw, J.E., 2006, Association between impaired glucose metabolism and quality of life: results from the Australian diabetes obesity and lifestyle study, Diabetes Research and Clinical Practice, vol 74, issue 2, Elsevier Ireland Ltd, Ireland, pp. 154-161.

Yallop, J.J., Clark, R.A., Croucher, J.L., Wilson, A., Sellar, B.N., Piterman, L., Tonkin, A.M., Krum, H., 2006, CHAT - A study of a nurse-led system of care, Australian Nursing Journal, vol 14, issue 4, Australian Nursing Federation, Australia, p. 19.

Buchan, H.H., Phillips, S.M., Weekes, L.M., Mackson, J.M., Boyden, A., Tonkin, A.M., 2006, Chronic heart failure: time to optimise methods of diagnosis in the community, Medical Journal of Australia, vol 184, Australasian Medical Publishing Company Pty. Ltd., Australia, pp. 423-424.

Tonkin, A.M., Chen, L., Nelson, M., 2006, Coronary heart disease: Multiple risk factors and risk assessment, Medicine Today, vol 7, issue 12, Medicine Today Pty. Ltd., Australia, pp. 14-18.

Tonkin, A.M., Eckermann, S., White, H.D., Friedlander, D., Glasziou, P.P., Magnus, P., Kirby, A., Mulray, S., Denton, M., Sallaberger, M., Hunt, D., Simes, R.J., 2006, Cost-effectiveness of cholesterol-lowering therapy with pravastatin in patients with previous acute coronary syndromes aged 65 to 74 years compared with younger patients: Results from the LIPID study, American Heart Journal, vol 151, issue 6, Mosby, Inc., USA, pp. 1305-1312.

Aroney, C., Aylward, P., Allan, R.M., Boyden, A.N., Brieger, D., Brown, A., Carroll, G.E., Chew, D.P.B., Clune, E., Flynn, M., Hunt, D., Jacobs, I.G., Kelly, A., Lea, T., Tan, K.S., Tonkin, A.M., Walker, T., Walsh, W., White, H.D., 2006, Guidelines for the management of acute coronary syndromes 2006, Medical Journal of Australia, vol 184, issue 8 (Suppl), Australasian Medical Publishing Company Pty. Ltd, Australia, pp. S9-S29.

Magliano, D.J., Rogers, S.L., Abramson, M.J., Tonkin, A.M., 2006, Hormone therapy and cardiovascular disease: A systematic review and meta-analysis review, BJOG: An International Journal of Obsterics and Gynaecology, vol 113, issue 1, Blackwell Publishing Ltd, UK, pp. 5-14.

Tonelli, M., Isles, C., Craven, T., Furberg, C., Tonkin, A.M., Pfeffer, M.A., Shepherd, J., Cobbe, S., Sacks, F., West, M., Packard, C., Curhan, G., 2006, Letter regarding article by Tonelli et al, "Effect of pravastatin on rate of kidney function loss in people with or at risk for coronary disease" - Response, Circulation, vol 113, issue 4, pp. 59-60.

Haas, S.J., Hage-Ali, R., Priestly, B.G., Tonkin, A.M., Demos, L.L., McNeil, J.J., Nelson, M.R., 2006, Long term safety of statins should be monitored, British Medical Journal, vol 333, issue 7569, BMJ Publishing Group, UK, p. 656.

Stocker, R., Pollicino, C., Gay, C.A., Nestel, P.J., Colquhoun, D., Whiting, M., Tonkin, A.M., Sullivan, D., Simes, J., 2006, Neither plasma coenzyme Q10 concentration, nor its decline during pravastatin therapy, is linked to recurrent cardiovascular disease events: a prospective case-control study from the LIPID study, Atherosclerosis, vol 187, issue 1, Elsevier Ireland Ltd, Ireland, pp. 198-204.

Tonkin, A.M., 2006, New acute coronary syndromes guidelines - addressing systems issues, Heart, Lung and Circulation, vol 15, issue 4, Elsevier, Australia, pp. 284-285.

Clark, R.A., Yallop, J.J., Wickett, D., Krum, H., Tonkin, A.M., Stewart, S., 2006, Nursing sans frontieres: A three year case study of multi-state registration of support nursing practice using information technology, Australian Journal of Advanced Nursing, vol 24, issue 1, Australian Nursing Federation, Australia, pp. 39-45.

Yallop, J.J., McAvoy, B., Croucher, J.L., Tonkin, A.M., Piterman, L., 2006, Primary health care research - essential but disadvantaged, Medical Journal of Australia, vol 185, issue 2, Australasian Medical Publishing Company Pty. Ltd, Australia, pp. 118-120.

Ioannides-Demos, L.L., Proietto, J., Tonkin, A.M., McNeil, J.J., 2006, Safety of drug therapies used for weight loss and treatment of obesity, Drug Safety, vol 29, issue 4, Adis International Ltd, New Zealand, pp. 277-302.

Tapp, R.J., Zimmet, P.Z., Harper, C., McCarty, D.J., Chitson, P., Tonkin, A.M., Soderberg, S., Taylor, H.R., Alberti, K.M.M., Tuomilehto, J., Shaw, J.E., 2006, Six year incidence and progression of diabetic retinopathy: results from the Mauritius diabetes complication study, Diabetes Research and Clinical Practice, vol 73, issue 3, Elsevier, Ireland, pp. 298-303.

Yallop, J.J., Chan, B.G.Y., Piterman, L., Tonkin, A.M., Forbes, A.B., Davidson, P.M., Clark, R.A., Halcomb, E., Nangle, A., Stewart, S., Croucher, J.L., Krum, H., 2006, The chronic heart-failure assistance by telephone (CHAT) study: assessment of telephone support for vulnerable patients with chronic disease, Asia Pacific Family Medicine Online, vol 5, issue 2, Blackwell Publishing Asia, Australia, pp. 1-10.

Krum, H., Tonkin, A.M., 2006, The rosuvastatin impact on ventricular remodeling cytokines and neurohormones (UNIVERSE) study, Journal of the American College of Cardiology, vol 47, issue 4, pp. 61-62.

Tonkin, A.M., Chen, L., 2006, Unanswered questions arising from the continuous relationship between glucometabolic state and cardiovascular risk, Current Atherosclerosis Reports, vol 8, issue 6, Current Science Inc., USA, pp. 439-440.

Nelson, M., Tonkin, A.M., Cicuttini, F.M., McNeil, J.J., 2005, COX-2 inhibitors: exemplars of the drug safety conundrum, Medical Journal of Australia, vol 182, Australian Medical Association, Australia, pp. 262-263.

Piterman, L., Zimmet, H.S., Krum, H., Tonkin, A.M., Yallop, J.J., 2005, Chronic heart failure--optimising care in general practice., Australian Family Physician, vol 34, issue 7, Royal Australian College of General Practioners, Australia, pp. 547-553.

Reid, I.R., Tonkin, A.M., Cannon, C.P., 2005, Comparison of the effects of pravastatin and atorvastatin on fracture incidence in the PROVE IT-TIMI 22 trial - Secondary analysis of a randomized controlled trial, Bone, vol 37, issue 2, Elsevier Inc., USA, pp. 190-191.

Ray, K.K., Cannon, C.P., McCabe, C.H., Cairns, R., Tonkin, A.M., Sacks, F.M., Jackson, G., Braunwald, E., 2005, Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: Results from the PROVE IT-TIMI 22 trial, Journal of the American College of Cardiology, vol 46, issue 8, Elsevier Inc., USA, pp. 1405-1410.

Tonelli, M., Keech, A., Shepherd, J., Sacks, F., Tonkin, A.M., Packard, C., Pfeffer, M., Simes, J., Isles, C., Furberg, C., West, M.J., Craven, T., Curhan, G., 2005, Effect of pravastatin in people with diabetes and chronic kidney disease, Journal of the American Society of Nephrology, vol 16, issue 12, American Society of Nephrology, USA, pp. 3748-3754.

Tonelli, M., Isles, C., Craven, T., Tonkin, A.M., Pfeffer, M.A., Shepherd, J., Sacks, F.M., Furberg, C., Cobbe, S.M., Simes, J., West, M.J., Packard, C., Curhan, G.C., 2005, Effect of pravastatin on rate of kidney function loss in people with or at risk for coronary disease, Circulation, vol 112, issue 2, Lippincott Williams & Wilkins, USA, pp. 171-178.

Baigent, C., Keech, A., Kearney, P.M., Blackwell, L., Buck, G., Pollicino, C., Kirby, A., Sourjina, T., Peto, R., Collins, R., Simes, R.J., Tonkin, A.M., 2005, Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins, Lancet, vol 366, issue 9493, Lancet Ltd, UK, pp. 1267-1278.

Bett, J.H.N., Tonkin, A.M., Thompson, P.L., Aroney, C., 2005, Failure of current public educational campaigns to impact on the initial response of patients with possible heart attack, Internal Medicine Journal, vol 35, issue 5, Wiley-Blackwell Publishing Asia, Australia, pp. 279-282.

Colquhoun, D., Keech, A., Nestel, P., Pollicino, C., Simes, J., Tonkin, A.M., 2005, Leptin but not adiponectin is a predictor of recurrent cardiovascular (CV) events in males: data from the LIPID study, European Heart Journal, vol 26, p. 317.

Nestel, P.J., Baghurst, K., Colquhoun, D.M., Simes, R.J., Mehalski, K., White, H.D., Tonkin, A.M., Kirby, A., Pollicino, C., 2005, Relation of diet to cardiovascular disease risk factors in subjects with cardiovascular disease in Australia and New Zealand: analysis of the long-term intervention with pravastatin in ischaemic disease trial, American Journal of Clinical Nutrition, vol 81, issue 6, American Society for Clinical Nutrition, Inc., USA, pp. 1322-1329.

Nelson, M.R., Tonkin, A.M., 2005, Secondary prevention of CHD., Australian Family Physician, vol 34, issue 6, Australian College of General Practitioners, Australia, pp. 433-440.

Nestel, P., Blankenberg, S., Simes, R.J., Kirby, A., Tonkin, A.M., 2005, Tissue inhibitor of metalloproteinase (TIMP-1) is a predictor of recurrent cardiovascular events in the LIPID study, European Heart Journal, vol 26, p. 257.

Tonkin, A.M., 2005, Towards consistency between guidelines and policy: lipid management-2005, Heart Lung and Circulation, vol 14, issue 4, Elsevier Australia, Australia, pp. 237-238.

Brown, A., Walsh, W., Lea, T., Tonkin, A.M., 2005, What Becomes of the Broken Hearted? Coronary Heart Disease as a Paradigm of Cardiovascular Disease and Poor Health Among Indigenous Australians, Heart, Lung and Circulation, vol 14, issue 3, Elsevier Australia, Australia, pp. 158-162.

Stewart, R.A.H., White, H.D., Kirby, A.C., Heritier, S.R., Simes, R.J., Nestel, P.J., West, M.J., Colquhoun, D.M., Tonkin, A.M., 2005, White blood cell count predicts reduction in coronary heart disease mortality with pravastatin, Circulation, vol 111, issue 14, Lippincott Williams & Wilkins, USA, pp. 1756-1762.

Hennekens, C.H., Sacks, F.M., Tonkin, A.M., Jukema, W., Byington, R.P., Pitt, B., Berry, D.A., Berry, S.M., Ford, N.F., Walker, A.J., Natarajan, K., Sheng-Lin, C., Fiedorek, F.T., Belder, R., 2004, Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: Randomized and observational comparisons of secondary prevention trials and their meta-analyses, Archives of Internal Medicine, vol 164, issue 1, American Medical Association, United States, pp. 40-44.

Tapp, R., Shaw, J.E., Zimmet, P.Z., Balkau, B., Chadban, S.J., Tonkin, A.M., Welborn, T.A., Atkins, R.C., 2004, Albuminuria is evident in the early stages of diabetes onset: results from the Australian Diabetes, Obesity, and Lifestyle study (AusDiab), American Journal of Kidney Diseases, vol 44, issue 5, WB Saunders Co., Philadelphia US, pp. 792-798.

Krum, H., Tonkin, A.M., Piterman, L., 2004, Bush telegraph - improving outcomes for rural and remote patients with chronic heart failure, Australian Family Physician, vol 33, issue 1-2, Royal Australian College of General Practitioners, Australia, pp. 76-77.

Colagiuri, S., Conway, B., Isbel, N.M., Knight, J.F., Mathew, T.H., Boyden, A., Clune, E., Tonkin, A.M., Cadilhac, A.D., Donnan, G.A., 2004, Consensus statement for the prevention of vascular disease, Australian Family Physician, vol 33, issue 4, Royal Australian College of General Practitioners, Australia, pp. 192-288.

Tonelli, M., Isles, C., Curhan, G.C., Tonkin, A.M., Pfeffer, M.A., Shepherd, J., Sacks, F.M., Furberg, C., Cobbe, S., Simes, J., Craven, T., West, M.J., 2004, Effect of pravastatin on cardiovascular events in people with chronic kidney disease, Circulation, vol 110, issue 12, Lippincott Williams & Wilkins, United States, pp. 1557-1563.

Colquhoun, D., Keech, A., Hunt, D., Marschner, I., Simes, J., Glasziou, P.P., White, H., Barter, P., Tonkin, A.M., 2004, Effects of pravastatin on coronary events in 2073 patients with low levels of both low-density lipoprotein cholesterol and high-density lipoprotein cholesterol: results from the LIPID study, European Heart Journal, vol 25, issue 9, Elsevier Ltd, UK, pp. 771-777.

Amarenco, P., Tonkin, A.M., 2004, Statins for stroke prevention:disappointment and hope, Circulation, vol 109 SupIII, Lippincott Williams & Wilkins, Philadelphia USA, pp. III-44-III-49.

Tonkin, A.M., 2004, Surely Polly'll behave and take her pills? The challenge of implementing guidelines, Heart, Lung and Circulation, vol 13, issue 1, Elsevier, Australia, pp. 7-9.

Tonkin, A.M., 2004, The Metabolic Syndrome(s)?, Current Atherosclerosis Reports, vol 6, Current Science Inc., United States, pp. 165-166.

Tonkin, A.M., 2004, The metabolic syndrome - a growing problem, European Heart Journal Supplements, vol 6, issue Supp. A, Elsevier Ltd, UK, pp. a37-a42.

Nelson, M.R., Tonkin, A.M., 2004, The why, who and how of CHD prevention, Medicine Today, vol 5, issue 12, Medicine Today Pty Ltd, Australia, pp. 14-23.

Bunker, S.J., Colquhoun, D.M., Esler, M.D., Hickie, I.B., Hunt, D., Jelinek, V.M., Oldenburg, B.F., Peach, H.G., Ruth, D., Tennant, C.C., Tonkin, A.M., 2003, "Stress" and coronary heart disease: Psychosocial risk factors, Medical Journal of Australia, vol 178, issue 6, Australasian Medical Publishing Company Pty. Ltd., Australia, pp. 272-276.

Magliano, D.J., Liew, D.Y., Pater, H., Kirby, A., Hunt, D., Simes, J., Sundararajan, V., Tonkin, A.M., 2003, Accuracy of the Australian National Death Index: comparison with adjudicated fatal outcomes among Australian participants in the Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) study, Australian and New Zealand Journal of Public Health, vol 27, issue 6, Public Health Association of Australia, Australia, pp. 649-653.

Tonkin, A.M., Lim, S.S., Schirmer, H., 2003, Cardiovascular risk factors: when should we treat?, Medical Journal of Australia, vol 178, issue 3, Australasian Medical Publishing Company Pty. Ltd., Australia, pp. 101-102.

Stewart, R.A.H., North, F.M., West, T.M., Sharples, K.J., Simes, R.J., Colquhoun, D.M., White, H., Tonkin, A.M., 2003, Depression and cardiovascular morbidity and mortality: Cause or consequence?, European Heart Journal, vol 24, issue 22, Oxford University Press, United Kingdom, France, pp. 2027-2037.

Hague, W., Forder, P., Simes, J., Hunt, D., Tonkin, A.M., 2003, Effect of pravastatin on cardiovascular events and mortality in 1516 women with coronary heart disease: results from the Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) study, American Heart Journal, vol 145, issue 4, Mosby, Inc., United States, pp. 643-651.

McNeil, J.J., Nelson, M.R., Tonkin, A.M., 2003, Public funding of large-scale clinical trials in Australia, Medical Journal of Australia, vol 179, issue 10, Australasian Medical Publishing Company Pty.Ltd, Australia, pp. 519-520.

Nelson, M.R., Reid, C.M., Beilin, L.J., Donnan, G.A., Johnston, C.I., Krum, H., Storey, E., Tonkin, A.M., McNeil, J.J., 2003, Rationale for a trial of low-dose aspirin for the primary prevention of major adverse cardiovascular events and vascular dementia in the elderly, Drugs & Aging, vol 20, issue 12, Adis International Ltd, Auckland New Zealand, pp. 897-903.

Tonkin, A.M., 2003, Risk prediction: Increasingly important, but questions still remain, Current Atherosclerosis Reports, vol 5, Current Science Inc., United States, pp. 1-2.

Keech, A., Colquhoun, D., Best, J.D., Kirby, A., Simes, R.J., Hunt, D., Hague, W., Beller, E., Arulchelvam, M., Baker, J., Tonkin, A.M., 2003, Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose: Results from the LIPID trial, Diabetes Care, vol 26, issue 10, American Diabetes Association, United States, pp. 2713-2721.

Krum, H., Tonkin, A.M., 2003, Why do phase III trials of promising heart failure drugs often fail? The contribution of regression to the truth, Journal of Cardiac Failure, vol 9, issue 5, Churchill Livingstone Inc Medical Publishers, Philadelphia USA, pp. 364-367.

Tonkin, A.M., Sloman, J.G., Kumar, A., Siddiqui, K.H., Noohi, F., Shimokawa, H., Takeshita, A., Takekoshi, N., Sasayama, S., Samad, A., Ortiz, E., Ng, R., Stephen, S.J., Kong, C.W., Chen, L.C., Chiang, C.E., Ding, P.Y., 2002, Cardiovascular medicine in the region - status report by the AsianPacific Society of Cardiology, Asian Cardiovascular & Thoracic Annals, vol 10, issue 3, Asia Publishing EXchange Ltd, Hong Kong, pp. 20A-30A.

Sacks, F., Tonkin, A.M., Craven, T., Pfeffer, M.A., Shepherd, J., Keech, A., Furberg, C., Braunwald, E., 2002, Coronary heart disease in patients with low LDL-Cholesterol: benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors, Circulation, vol 105, issue 12, Lippincott Williams & Wilkins, United States, pp. 1424-1428.

Tonkin, A.M., 2002, Does lowering blood pressure prevent recurrent stroke?, Medical Journal of Australia, vol 176, issue 6, Australasian Medical Publishing Company Pty Ltd, Australia, pp. 283-284.

Dudman, N., Hunt, D., MacMahon, S., Neal, B., Richards, M., Simes, J., Tonkin, A.M., Wilcken, D., 2002, Dose-dependent effects of folic acid on plasma homocysteine in a randomized trial conducted among 723 individuals with coronary heart disease, European Heart Journal, vol 23, issue 19, Oxford University Press, United Kingdom, France, pp. 1509-1515.

Simes, J., Furberg, C., Braunwald, E., Davis, B.R., Ford, I., Tonkin, A.M., Shepherd, J., 2002, Effects of pravastatin on mortality in patients with and without coronary heart disease across a broad range of cholesterol levels, European Heart Journal, vol 23, issue 3, Oxford University Press, United Kingdom, France, pp. 207-215.

Tonkin, A.M., 2002, Effects of the vasopeptidase inhibitor, omapatrilat, in 723 patients with coronary heart disease, Journal of Renin-Angiotensin-Aldosterone System, vol 3, issue 4, Sage Science Press, United Kingdom, pp. 270-276.

Tonkin, A.M., Dujovne, C.A., 2002, Further evidence of the need to establish treatment safety as well as efficacy in randomized controlled trials, Current Opinion in Lipidology, vol 13, issue 6, Lippincott Williams & Wilkins, Ltd., United Kingdom, pp. 591-593.

Harrap, S.B., Zammit, K.S., Wong, Z.Y.H., Williams, F.M., Bahlo, M., Tonkin, A.M., Anderson, S.T., 2002, Genome-wide linkage analysis of the acute coronary syndrome suggests a locus on chromosome 2, Arteriosclerosis, Thrombosis, and Vascular Biology, vol 22, issue 5, Lippincott Williams & Wilkins, Philadelphia USA, pp. 874-878.

Freedman, S.B., Tonkin, A.M., 2002, Global cardiology comes to Australia: 14th World Congress of Cardiology, Sydney, 5-9 May 2002, Medical Journal of Australia, vol 177, Australasian Medical Publishing Company Pty Ltd, Australia, pp. 473-475.

Simes, J., Hunt, D., Kirby, A., Tonkin, A.M., Keech, A., Aylward, P., Colquhoun, D., Glasziou, P.P., Hague, W., MacMahon, S., Thompson, P.L., West, M.J., White, H.D., 2002, Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-up, Lancet, vol 359, issue 9315, The Lancet Publishing Group, United Kingdom, pp. 1379-1387.

Simes, J., Marschner, I., Hunt, D., Colquhoun, D., Sullivan, D., Stewart, R., Hague, W., Keech, A., Thompson, P.J., White, H., Shaw, J., Tonkin, A.M., 2002, Relationship between lipid levels and clinical outcomes in the Long-Term Intervention with Pravastatin Disease (LIPID) Trial: to what extent is the reduction in coronary events with pravastatin explained by on-study lipid levels?, Circulation, vol 105, issue 10, Lippincott Williams & Wilkins, United States, pp. 1162-1169.

Tonkin, A.M., Harris, P.I., 2002, Relevancy of the National Heart Foundation, Heart, Lung and Circulation, vol 11, Elsevier Australia, Australia, pp. 1-2.

West, M.J., White, H., Simes, J., Kirby, A., Watson, J., Anderson, N.E., Hankey, G.J., Wonders, S., Hunt, D., Tonkin, A.M., 2002, Risk factors for non-haemorrhagic stroke in patients with coronary heart disease and the effect of lipi-modifying therapy with pravastatin, Journal of Hypertension, vol 20, issue 12, Lippincott Williams & Wilkins, Ltd., United Kingdom, United States, pp. 2513-2517.

Pfeffer, M.A., Keech, A., Sacks, F., Cobbe, S., Tonkin, A.M., Byington, R.P., Davis, B.R., Friedman, C.P., Braunwald, E., 2002, Safety and tolerability of pravastatin in long-term clinical trials: Prospective Pravastatin Pooling project, CIrculation, vol 105, issue 20, Lippincott Williams & Wilkins, United States, pp. 2341-2346.

Hunt, D., Young, P., Simes, J., Hague, W., Mann, S., Owensby, D., Lane, G., Tonkin, A.M., 2001, Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are equal to or exceed those seen in younger patients: results from the LIPID trial, Annals of Internal Medicine, vol 134, issue 10, American College of Physicians, United States, pp. 931-940.

Krum, H., Tonkin, A., Currie, R., Djundjek, R., Johnston, C.I., 2001, Chronic heart failure in Australian general practice. The Cardiac Awareness Survey and Evaluation (CASE) study, Medical Journal of Australia, vol 174, Australian Medical Association, Australia, pp. 439-444.

Reid, I.R., Hague, W., Emberson, J., Baker, J., Tonkin, A.M., Hunt, D., MacMahon, S., Sharpe, N., 2001, Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomised controlled trial, The Lancet, vol 357, issue 9255, Lancet Ltd, London England, pp. 509-512.

Krum, H., Tonkin, A.M., Jelinek, M.V., Harris, M., McNeil, J.J., Hunt, D., Kaye, D., Burrell, L.M., Arnolda, L., Keogh, A., Bergin, P., Walsh, W., Sindone, A., Hare, D.L., Holst, D.P., O'Driscoll, G., Horowitz, J.D., Richardson, M., 2001, Guidelines for management of patients with chronic heart failure in Australia, Medical Journal of Australia, vol 174, Australasian Medical Publishing Company Pty Ltd, Australia, pp. 459-466.

Best, J.D., Boyden, A., Cooper, C., Gillam, I., Mansfield, P., Nestel, P., Parsons, M.W., Ruth, D., Sheerin, N., Thompson, P.L., Tonkin, A.M., Vale, M.J., 2001, Lipid Management Guidelines -2001, Medical Journal of Australia, vol 175, Australasian Medical Publishing Company Pty Ltd, Sydney NSW Australia, pp. 57-88.

Sacks, F., Tonkin, A.M., Shepherd, J., Braunwald, E., Cobbe, S., Hawkins, C.M., 2000, Effect of Pravastatin on Coronary Disease Events in Subgroups Defined by Coronary Risk Factors, Circulation, vol 102, Lippincott Williams & Wilkins, US, pp. 1893-1900.

Tonkin, A.M., Colquhoun, D., Emberson, J., Hague, W., Keech, A., MacMahon, S., Shaw, J., Simes, R.J., Thompson, P.L., White, H.D., Hunt, D., 2000, Effects of pravastatin in 3260 patients with unstable angina: results from the LIPID study, The Lancet, vol 355, issue Dec 2, pp. 1871-1875.

Tonkin, A.M., Aroney, C., Boyden, A., Jelinek, M.V., Thompson, P.L., White, H.D., 2000, Management of unstable angina Guidelines - 2000, Medical Journal of Australia, vol 173, Austral. Med Public Co, Australia, pp. 55-88.

White, H.D., Simes, R., Anderson, N.E., Hankey, G.J., Watson, J.D., Hunt, D., Colquhoun, D., Glasziou, P.P., MacMahon, S., Kirby, A., West, M.J., Tonkin, A.M., 2000, Pravastatin therapy and the risk of stroke, N Engl J Med, vol 343, Massachusetts Medical Society, US, pp. 317-326.

Conference Proceedings

Krum, H., Tonkin, A., Currie, R., Djundjek, R., Johnston, C.I., 1999, Pharmacological management of chronic heart failure (CHF) in Australian general practice: tthe cardiac awareness survey and evaluation (case) study, Cardiac Society of Australia and New Zealand 47th Annual Scientific Meeting - Final Program and Extracts, Wellington, NZ, 7-11th Aug, 1999, Cardiac Society of Australia and New Zealand, Southbank Vic Australia, p. 142.

Other

Tonkin, A.M., Hickie, I.B., Colquhoun, D., Heistaro, S., Dunbar, J.A., 2005, Epidemiologists and researchers continue to overlook the obvious, Rapid reponse on www.bmj.com, 21 October 2005., BMJ Group, United Kingdom.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Polypharmacy in the heart failure patient: are all prescribed drug classes required?.

Supervisors:

Krum, H (Main), Tonkin, A (Associate).

Completed Supervision

Student:

Barr, E.

Program of Study:

The contribution of impaired glucose metabolism to cardiovascular disease and mortality in Australians. (PHD) 2009.

Supervisors:

Shaw, J (Joint), Tonkin, A (Joint-Co).

Student:

Beauchamp, A.

Program of Study:

Socioeconomic status as a determinant of cardiovascular disease. (PHD) 2010.

Supervisors:

Tonkin, A (Main), Peeters, A (Associate), Wolfe, R (Associate).

Student:

Cameron, A.

Program of Study:

The metabolic syndrome: its validity, causes, consequences and uses. (PHD) 2009.

Supervisors:

Shaw, J (Joint-Co), Tonkin, A (Joint).

Student:

Chen, L.

Program of Study:

Improving risk prediction for cardiovascular disease and type 2 diabetes in the general Australian population. (PHD) 2010.

Supervisors:

Tonkin, A (Main), Shaw, J (Associate).

Student:

Harriss, L.

Program of Study:

Alcohol and dietary patterns as determinants of cardiovascular disease in the Melbourne Collaborative Cohort Study. (PHD) 2008.

Supervisors:

Tonkin, A (Main), O''Dea, K (Associate).

Student:

Tapp, R.

Program of Study:

EPIDEMIOLOGY OF DIABETES-RELATED COMPLICATIONS IN AN AUSTRALIAN POPULATION. (PHD) 2004.

Supervisors:

Tonkin, A (Main), Shaw, J (External).