Ms Traude Beilharz - Researcher Profile

Biography

Traude works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: La Trobe University

Year awarded: 2001

Publications

Book Chapters

Beilharz, T., Preiss, T., 2011, Polyadenylation state microarray (PASTA) analysis, in Yeast Systems Biology: Methods and Protocols, eds Juan I Castrillo & Stephen G Oliver, Humana Press, USA, pp. 133-147.

Beilharz, T.H., Humphreys, D.T., Preiss, T., 2010, miRNA effects on mRNA closed-loop formation during translation initiation, in miRNA Regulation of the Translational Machinery, eds RE Rhoads, Springer, Germany, pp. 99-112.

Journal Articles

Sengupta, M.S., Low, W.(., Patterson, J.R., Kim, H., Traven, A., Beilharz, T.H., Colaiacovo, M.P., Schisa, J.A., Boag, P.R., 2013, ifet-1 is a broad scale translational repressor required for normal P granule formation in C. elegans, Journal Of Cell Science [P], vol E-pub, The Company of Biologists Ltd, UK, pp. 1-39.

Hewitt, V.L., Heinz, E., Shingu-Vazquez, M.A., Qu, Y., Jelicic, B., Lo, T.L., Beilharz, T.H., Dumsday, G., Gabriel, K., Traven, A., Lithgow, T.J., 2012, A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 109, issue 49, National Academy of Sciences, USA, pp. E3358-E3366.

Qu, Y., Jelicic, B., Pettolino, F.A., Perry, A.J., Lo, T., Hewitt, V.L., Bantun, F., Beilharz, T.H., Peleg, A.y., Lithgow, T.j., Djordjevic, J., Traven, A., 2012, Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence, Eukaryotic Cell [P], vol 11, issue 4, American Society for Microbiology, USA, pp. 532-544.

Uwamahoro, N., Qu, Y., Jelicic, B., Lo, T., Beaurepaire, C., Bantun, F., Quenault, T., Boag, P., Ramm, G., Callaghan, J.M., Beilharz, T.H., Nantel, A., Peleg, A.Y., Traven, A., 2012, The functions of mediator in Candida albicans support a role in shaping species-specific gene expression, Plos Genetics [P], vol 8, issue 4 (Art. ID: e1002613), Publc Library of Science, USA, pp. 1-18.

Lo, T.L., Qu, Y., Uwamahoro, N., Quenault, T.L., Beilharz, T.H., Traven, A., 2012, The mRNA decay pathway regulates expressionof the Flo11 adhesin and biofilm formation in Saccharomyces cerevisiae, Genetics [P], vol 191, issue 4, Genetics Society of America, USA, pp. 1387-1391.

Traven, A., Janicke, A., Harrison, P., Swaminathan, A., Seemann, T., Beilharz, T.H., 2012, Transcriptional profiling of a yeast colony provides new insight into the heterogeneity of multicellular fungal communities, PLoS ONE [P], vol 7, issue 9, Public Library of Science, USA, pp. e46243.1-e46243.11.

Janicke, A., Vancuylenberg, J., Boag, P., Traven, A., Beilharz, T.H., 2012, ePAT: a simple method to tag adenylated RNA to measure poly(A)-tail length and other 3' RACE applications, Rna-A Publication Of The Rna Society [P], vol 18, issue 6, Cold Spring Harbor Laboratory Press, USA, pp. 1289-1295.

Dagley, M.J., Gentle, I.E., Beilharz, T.H., Pettolino, F.A., Djordjevic, J., Lo, T., Uwamahoro, N., Rupasinghe, T.W.T., Tull, D., McConville, M.J., Beaurepaire, C., Nantel, A., Lithgow, T.J., Mitchell, A.P., Traven, A., 2011, Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2, Molecular Microbiology [P], vol 79, issue 4, Wiley-Blackwell Publishing Ltd, UK, pp. 968-989.

Boyd, S.E., Keith, J., Traven, A., Beilharz, T., 2011, Probing connectivity between transcriptional and post-transcriptional gene networks, Microbiology Australia [P], vol 32, issue 4, The Australian Society for Microbiology Inc, Australia, pp. 166-168.

Clancy, J.L., Wei, G.H., Echner, N., Humphreys, D.T., Beilharz, T.H., Preiss, T., 2011, mRNA isoform diversity can obscure detection of miRNA-mediated control of translation, Rna-A Publication Of The Rna Society [P], vol 17, issue 6, Cold Spring Harbor Laboratory Press, USA, UK, pp. 1025-1031.

Traven, A., Beilharz, T.H., Lo, T.L., Lueder, F.B., Preiss, T., Heierhorst, J., 2009, The Ccr4-Pop2-NOT mRNA deadenylase contributes to septin organization in Saccharomyces cerevisiae, Genetics [P], vol 182, issue 4, Genetics Society of America, USA, pp. 955-966.

Beilharz, T.H., Preiss, T., 2009, Transcriptome-wide measurement of mRNA polyadenylation state, Methods [P], vol 48, issue 3, Academic Press, USA, pp. 294-300.

Beilharz, T.H., Humphreys, D.T., Clancy, J.L., Thermann, R., Martin, D.I., Hentze, M.W., Preiss, T., 2009, microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells, PLoS ONE [P], vol 4, issue 8, Public Library of Science, USA, pp. e6783-1-e6783-12.

Lackner, D.H., Beilharz, T.H., Marguerat, S., Mata, J., Watt, S., Schubert, F., Preiss, T., Bahler, J., 2007, A network of multiple regulatory layers shapes gene expression in fission yeast, Molecular Cell [P], vol 26, issue 1, Cell Press, USA, pp. 145-155.

Beilharz, T.H., Preiss, T., 2007, Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome, Rna-A Publication Of The Rna Society [P], vol 13, issue 7, Cold Spring Harbor Laboratory Press, USA, pp. 982-997.

Woolstencroft, R.N., Beilharz, T.H., Crook, M.A., Preiss, T., Durocher, D., Tyers, M., 2006, Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length, Journal Of Cell Science [P], vol 119, issue Pt 24, The Company of Biologists Ltd, UK, pp. 5178-5192.

Burri, L., Vascotto, K., Gentle, I.E., Chan, N.C., Beilharz, T., Stapleton, D.I., Ramage, L., Lithgow, T.J., 2006, Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae, The FEBS Journal, vol 273, issue 7, Wiley-Blackwell Publishing Ltd, UK , Denmark, pp. 1507-1515.

Youker, R.T., Walsh, P., Beilharz, T., Lithgow, T.J., Brodsky, J.L., 2004, Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast, Molecular Biology of the Cell, vol 15, issue 11, American Society for Cell Biology, USA, pp. 4787-4797.

Burri, L., Varlamov, O., Doege, C.A., Hofmann, K., Beilharz, T., Rothman, J.E., Sollner, T.H., Lithgow, T.J., 2003, A SNARE required for retrograde transport to the endoplasmic reticulum, Proceedings of the National Academy of Sciences of the United States of America, vol 100, issue 17, National Academy of Sciences, USA, pp. 9873-9877.

Beilharz, T., Egan, B., Silver, P.A., Hofmann, K., Lithgow, T.J., 2003, Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae, Journal of Biological Chemistry, vol 278, issue 10, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 8219-8223.

Miller, E.A., Beilharz, T.H., Malkus, P.N., Lee, M.C., Hamamoto, S., Orci, L., Schekman, R., 2003, Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles, Cell [P], vol 114, issue 4, Cell Press, USA, pp. 497-509.

Allen, R., Egan, B., Gabriel, K., Beilharz, T., Lithgow, T.J., 2002, A conserved proline residue is present in the transmembrane-spanning domain of Tom7 and other tail-anchored protein subunits of the TOM translocase, FEBS Letters, vol 514, issue 2-3, Elsevier BV, The Netherlands & Denmark, pp. 347-350.

Chavez, S., Beilharz, T., Rondon, A.G., Erdjument-Bromage, H., Tempst, P., Svejstrup, J.Q., Lithgow, T.J., Aguilera, A., 2000, A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae, The EMBO Journal, vol 19, issue 21, Nature Publishing Group, UK & Germany, pp. 5824-5834.

Gratzer, S., Beilharz, T., Beddoe, T.C., Henry, M.F., Lithgow, T.J., 2000, The mitochondrial protein targeting suppressor (mts1) mutation maps to the mRNA-binding domain of Npl3p and affects translation on cytoplasmic polysomes, Molecular Microbiology, vol 35, issue 6, Wiley-Blackwell Publishing Ltd, UK, pp. 1277-1285.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Characterisation of RNA-protein interactions using PAR-CLIP.

Supervisors:

Beilharz, T (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The Proteins that control the rate of poly (A) - tail deadenylation in Saccharomyces cerevisiae.

Supervisors:

Beilharz, T (Main).