Dr Ian Larson - Researcher Profile

Biography

Position

Senior Lecturer
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Delivery, Disposition and Dynamics
Monash Institute of Pharmaceutical Sciences

Qualifications

PHD

Institution: University of Melbourne

Year awarded: 1999

Publications

Journal Articles

Zhou, Q., Qu, L., Gengenbach, T.R., Larson, I.C., Stewart, P.J., Morton, D.A.V., 2013, Effect of surface coating with magnesium stearate via mechanical dry powder coating approach on the aerosol performance of micronized drug powders from dry powder inhalers, Aaps Pharmscitech [P], vol 14, issue 1, Springer, New York USA, pp. 38-44.

Soon, R.L., Li, J., Boyce, J.D., Harper, M., Adler, B., Larson, I.C., Nation, R.L., 2012, Cell surface hydrophobicity of colistin-susceptible vs resistant Acinetobacter baumannii determined by contact angles: methodological considerations and implications, Journal Of Applied Microbiology [P], vol 113, issue 4, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 940-951.

Behara, S.R.B., Larson, I.C., Kippax, P., Stewart, P.J., Morton, D.A.V., 2012, Insight into pressure drop dependent efficiencies of dry powder inhalers, European Journal of Pharmaceutical Sciences [P], vol 46, issue 3, Elsevier BV, Netherlands, pp. 142-148.

Das, S.C., Behara, S.R.B., Bulitta, J.B., Morton, D.A.V., Larson, I.C., Stewart, P.J., 2012, Powder strength distributions for understanding de-agglomeration of lactose powders, Pharmaceutical Research [P], vol 29, issue 10, Springer New York LLC, United States, pp. 2926-2935.

Dong, Y.D.C., Larson, I.C., Barnes, T., Prestidge, C.A., Allen, S., Chen, X., Roberts, C.J., Boyd, B.J., 2012, Understanding the interfacial properties of nanostructured liquid crystalline materials for surface-specific delivery applications, Langmuir [P], vol 28, issue 37, American Chemical Society, Washington DC, USA, pp. 13485-13495.

Dong, Y., Larson, I., Barnes, T., Prestidge, C., Boyd, B., 2011, Adsorption of nonlamellar nanostructured liquid-crystalline particles to biorelevant surfaces for improved delivery of bioactive compounds., ACS Applied Materials & Interfaces [P], vol 3, issue 5, American Chemical Society, USA, pp. 1771-1780.

Behara, S., Larson, I., Kippax, P., Morton, D., Stewart, P., 2011, An approach to characterising the cohesive behaviour of powders using a flow titration aerosolisation based methodology, Chemical Engineering Sciences [P], vol 66, issue 8, Elsevier, Netherlands, pp. 1640-1648.

Dube, A., Nicolazzo, J., Larson, I., 2011, Assessment of plasma concentrations of (-)-epigallocatechin gallate in mice following administration of a dose reflecting consumption of a standard green tea beverage, Food Chemistry [P], vol 128, issue 1, Elsevier, Netherlands, pp. 7-13.

Zhou, Q., Denman, J., Gengenbach, T., Das, S., Qu, L., Zhang, H., Larson, I., Stewart, P., Morton, D., 2011, Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach, Journal of Pharmaceutical Sciences [P], vol 100, issue 8, John Wiley & Sons, Inc., United States, pp. 3421-3430.

Dube, A., Nicolazzo, J., Larson, I., 2011, Chitosan nanoparticles enhance the plasma exposure of (-) -epigallocatechin gallate in mice through an enhancement in intestinal stability, European Journal of Pharmaceutical Sciences [P], vol 44, Elsevier, Netherlands, pp. 422-426.

Soon, R., Velkov, T., Chiu, F., Thompson, P., Kancharla, R., Roberts, K., Larson, I., Nation, R., Li, J., 2011, Design, synthesis, and evaluation of a new fluorescent probe for measuring polymyxin-lipopolysaccharide binding interactions, Analytical Biochemistry [P], vol 409, issue 2, Academic Press, United States, pp. 273-283.

Das, S., Larson, I., Morton, D., Stewart, P., 2011, Determination of the polar and total surface energy distributions of particulates by inverse gas chromatography, Langmuir [P], vol 27, issue 2, American Chemical Society, USA, pp. 521-523.

Soon, R., Nation, R., Cockram, S., Moffatt, J., Harper, M., Adler, B., Boyce, J., Larson, I., Li, J., 2011, Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment, Journal Of Antimicrobial Chemotherapy [P], vol 66, issue 1, Oxford University Press, United Kingdom, pp. 126-133.

Soon, R., Nation, R., Harper, M., Adler, B., Boyce, J., Tan, C., Li, J., Larson, I., 2011, Effect of colistin exposure and growth phase on the surface properties of live acinetobacter baumannii cells examined by atomic force microscopy, International Journal of Antimicrobial Agents [P], vol 38, issue 6, Elsevier, Netherlands, pp. 493-501.

Zhou, Q., Qu, L., Larson, I., Stewart, P., Morton, D., 2011, Effect of mechanical dry particle coating on the improvement of powder flowability for lactose monohydrate: A model cohesive pharmaceutical powder, Powder Technology [P], vol 207, issue 1-3, Elsevier, The Netherlands, pp. 414-421.

Zhou, Q., Qu, L., Gegenbach, T., Denman, J., Larson, I., Stewart, P., Morton, D., 2011, Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties, International Journal of Pharmaceutics [P], vol 413, Elsevier/North-Holland Biomedical Press, Netherlands, pp. 36-43.

Behara, S., Kippax, P., Larson, I., Morton, D., Stewart, P., 2011, Kinetics of emitted mass - a study with three dry powder inhaler devices, Chemical Engineering Sciences [P], vol 66, Pergamon Press, United Kingdom, pp. 5284-5292.

Behara, S., Kippax, P., McIntosh, M., Morton, D., Larson, I., Stewart, P., 2011, Structural influence of cohesive mixtures of salbutamol sulphate and lactose on aerosolisation and de-agglomeration behaviour under dynamic conditions, European Journal of Pharmaceutical Sciences [P], vol 42, issue 3, Elsevier, The Netherlands, pp. 210-219.

Behara, S., Larson, I., Kippax, P., Morton, D., Stewart, P., 2011, The kinetics of cohesive powder de-agglomeration from three inhaler devices, International Journal of Pharmaceutics [P], vol 421, Elsevier/North-Holland Biomedical Press, Netherlands, pp. 72-81.

Das, S., Zhou, Q., Morton, D., Larson, I., Stewart, P., 2011, Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate, European Journal of Pharmaceutical Sciences [P], vol 43, Elsevier Science B.V, Netherlands, pp. 325-333.

Dube, A., Nicolazzo, J., Larson, I.C., 2010, Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (-)-epigallocatechin gallate, European Journal of Pharmaceutical Sciences [P], vol 41, Elsevier B.V., Netherlands, pp. 219-225.

Dube, A., Ng, K., Nicolazzo, J., Larson, I.C., 2010, Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution, Food Chemistry [P], vol 122, Elsevier, Netherlands, pp. 662-667.

Zhou, Q., Qu, L., Larson, I.C., Stewart, P.J., Morton, D.A.V., 2010, Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach, International Journal of Pharmaceutics [P], vol 394, issue 1-Feb, Elsevier, Netherlands, pp. 50-59.

Zhou, Q., Armstrong, B., Larson, I.C., Stewart, P.J., Morton, D.A.V., 2010, Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating, Journal of Pharmaceutical Sciences [P], vol 99, issue 2, John Wiley & Sons, Inc, USA, pp. 969-981.

Dong, C.Y., Tilley, A.J., Larson, I.C., Lawrence, J., Amenitsch, H., Rappolt, M., Hanley, T.L., Boyd, B.J., 2010, Nonequilibrium effects in self-assembled mesophase materials: unexpected supercooling effects for cubosomes and hexosomes, Langmuir [P], vol 26, issue 11, American Chemical Society, USA, pp. 9000-9010.

Nguyen, T., Hanley, T., Porter, C., Larson, I., Boyd, B., 2010, Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water soluble drugs I. Phase behaviour in physiologically-relevant media, Journal of Pharmacy and Pharmacology [P], vol 62, John Wiley & Sons Ltd., United Kingdom, pp. 844-855.

Nguyen, T., Hanley, T., Porter, C., Larson, I., Boyd, B., 2010, Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water-soluble drugs II. In-vivo evaluation, Journal of Pharmacy and Pharmacology [P], vol 62, issue 7, John Wiley & Sons Ltd., United Kingdom, pp. 856-865.

Zhou, Q., Armstrong, B., Larson, I., Stewart, P., Morton, D., 2010, Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders, European Journal of Pharmaceutical Sciences [P], vol 40, issue 5, Elsevier BV, Netherlands, pp. 412-421.

Ta, H., Dass, C.R., Larson, I.C., Choong, P.F., Dunstan, D.E., 2009, A chitosan-dipotassium orthophosphate hydrogel for the delivery of doxorubicin in the treatment of osteosarcoma, Biomaterials [P], vol 30, issue 21, Elsevier BV, Netherlands, pp. 3605-3613.

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2009, Agglomerate properties and dispersibility changes of salmeterol xinafoate from powders for inhalation after storage at high relative humidity, European Journal of Pharmaceutical Sciences [P], vol 37, issue 3-4, Elsevier BV, Netherlands, pp. 442-450.

Soon, R.L., Nation, R.L., Hartley, P., Larson, I.C., Li, J., 2009, Atomic force microscopy investigation of the morphology and topography of colistin-heteroresistant Acinetobacter baumannii strains as a function of growth phase and in response to colistin treatment, Antimicrobial Agents And Chemotherapy [P], vol 53, issue 12, American Society for Microbiology, United States, pp. 4979-4986.

Ta, H., Han, H., Larson, I.C., Dass, C.R., Dunstan, D., 2009, Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system, International Journal of Pharmaceutics, vol 371, issue 1-2, Elsevier BV, The Netherlands, pp. 134-141.

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2009, Influence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation, Journal of Pharmaceutical Sciences, vol 98, John-Wiley & Sons, Inc., USA, pp. 1015-1027.

Adi, H., Larson, I.C., Stewart, P.J., 2009, Influence of the polydispersity of the added fine lactose on the dispersion of salmeterol xinafoate from mixtures for inhalation, European Journal of Pharmaceutical Sciences, vol 36, issue 2-3, Elsevier BV, Netherlands, pp. 265-274.

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2009, Surface energy changes and their relationship with the dispersibility of salmeterol xinafoate powders for inhalation after storage at high RH, European Journal of Pharmaceutical Sciences [P], vol 38, issue 4, Elsevier BV, The Netherlands, pp. 347-354.

Dong, Y., Dong, A., Larson, I.C., Rappolt, M., Amenitsch, H., Hanley, T.L., Boyd, B.J., 2008, Impurities in commercial phytantriol significantly alter its lyotropic liquid-crystalline phase behavior, Langmuir, vol 24, issue 13, American Chemical Society, USA, pp. 6998-7003.

Adi, H., Larson, I.C., Chiou, H., Young, P.M., Traini, D., Stewart, P.J., 2008, Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios, Journal of Pharmaceutical Sciences, vol 97, issue 1, Wiley-Liss Inc, US, pp. 3140-3152.

Adi, H., Larson, I.C., Stewart, P.J., 2007, Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation, International Journal of Pharmaceutics, vol 337, issue 1-2, Elsevier, Netherlands, pp. 229-238.

Adi, H., Larson, I.C., Stewart, P.J., 2007, Laser diffraction particle sizing of cohesive lactose powders, Powder Technology, vol 179, issue 1-2, Elsevier, Switzerland, pp. 90-94.

Adi, H., Larson, I.C., Stewart, P.J., 2007, Use of milling and wet sieving to produce narrow particle size distributions of lactose monohydrate in the sub-sieve range, Powder Technology, vol 179, issue 1-2, Elsevier, Switzerland, pp. 95-99.

Adi, H., Larson, I.C., Chiou, H., Young, P.M., Traini, D., Stewart, P.J., 2006, Agglomerate strength and dispersion of salmeterol xinafoate from powder mixtures for inhalation, Pharmaceutical Research, vol 23, issue 11, Springer New York LLC, USA, pp. 2556-2565.

Dong, Y., Larson, I.C., Hanley, T.L., Boyd, B.J., 2006, Bulk and dispersed aqueous phase behavior of phytantriol: effect of vitamin E acetate and F127 polymer on liquid crystal nanostructure, Langmuir, vol 22, issue 23, American Chemical Society, USA, pp. 9512-9518.

Ralston, J., Larson, I.C., Rutland, M.W., Feiler, A.A., Kleijn, M., 2005, Atomic force microscopy and direct surface force measurements (IUPAC technical report), Pure and Applied Chemistry, vol 77, issue 12, International Union of Pure and Applied Chemistry, USA, pp. 2149-2170.

Murphy, B.M., Prescott, S.W., Larson, I.C., 2005, Measurement of lactose crystallinity using Raman spectroscopy, Journal of Pharmaceutical and Biomedical Analysis, vol 38, issue 1, Elsevier, The Netherlands, pp. 186-190.

Islam, M.N., Stewart, P.J., Larson, I.C., Hartley, P., 2005, Surface roughness contribution to the adhesion force distribution of salmeterol xinafoate on lactose carriers by atomic force microscopy, Journal of Pharmaceutical Sciences, vol 94, issue 7, John Wiley & Sons, Inc., USA, pp. 1500-1511.

Islam, M.N., Stewart, P.J., Larson, I.C., Hartley, P., 2004, Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures, Journal of Pharmaceutical Sciences, vol 93, issue 4, Wiley-Liss, Inc., Hoboken USA, pp. 1030-1038.

Islam, M.N., Stewart, P.J., Larson, I.C., Hartley, P., 2004, Lactose surface modification by decantation: are drug-fine lactose ratios the key to better dispersion of slametereol xinafoate from lactose-intercative mixtures?, Pharmaceutical Research, vol 21, issue 3, Kluwer Academic/Plenum Publishers, Dordrecht The Netherlands, pp. 492-499.

Woodward, N.C., Snowden, M.J., Chowdhry, B.Z., Jenkins, P., Larson, I.C., 2002, Measurement of the Interaction Forces between Poly(N-Isopropylacrylamide-Acrylic Acid) Microgel and Silica Surfaces by Colloid Probe Microscopy, Langmuir, vol 18, American Chemical Society, USA, pp. 2089-2095.

Feiler, A.A., Larson, I.C., Jenkins, P., Attard P, 2000, A Quantitative Study of Interaction Forces and Friction in Aqueous Colloidal Systems, Langmuir, vol 16, American Chemical Society, USA, pp. 10269-10277.

Feiler, A.A., Attard P, Larson, I.C., 2000, Calibration of the Torsional Spring Constant and the Lateral Photodiode Response of Frictional Force Microscopes, Review of Scientific Instruments, vol 71, issue 7, American Institute of Physics, USA, pp. 2746-2750.

Attard P, Antelmi, D., Larson, I.C., 2000, Comparison of the Zeta Potential with the Diffuse Layer Potential from Charge Titration, Langmuir, vol 16, issue 4, American Chemical Society, USA, pp. 1542-1552.

Larson, I.C., Attard P, 2000, Surface Charge of Silver Iodide and Several Metal Oxides. Are All Surfaces Nernstian?, Journal of Colloid and Interface Science, vol 227, Academic Press/Elsevier, pp. 152-163.

Conference Proceedings

Das, S.C., Behara, S.R.B., Bulitta, J.B., Morton, D.A.V., Larson, I.C., Stewart, P.J., 2012, Superiority of powder strength distribution for understanding de-agglomeration of lactose powders, Respiratory Drug Delivery 2012, May 13-17, 2012, Virginia Commonwealth University, United States, pp. 585-590.

Behara, S., Larson, I., Kippax, P., Morton, D., Stewart, P., 2011, How important is powder structure on the kinetics of emptying and de-agglomeration from devices?, DDL 22, 07-09/12/2011, The Aerosol Society, UK, pp. 367-370.

Das, S., Behara, S., Morton, D., Larson, I., Stewart, P., 2011, Investigating the dispersibility of lactose powders by measuring the total surface energy distributions with an inverse gas chromatography method at finite dilution, Respiratory Drug Delivery 2011, 03-06/05/2011, Davis Healthcare, USA, pp. 359-362.

Jong, T., Li, J., Hale, J., Morton, D., Larson, I., 2011, Investigating the particle engineering of colistin for pulmonary delivery, ECPS 2011, 01/03-31/03/2011, MDPI open access publishing, Basel, Switzerland, pp. 1-6.

Morton, D., Jong, T., Li, J., Hale, J., Nation, R., Larson, I., 2011, Investigating the particle engineering of colistin for pulmonary delivery, Respiratory Drug Delivery Europe 2011, 03-06/05/2011, RDD Online and Aptar Pharm, USA, pp. 367-371.

Behara, S., Kippax, P., Morton, D., Larson, I., Stewart, P., 2011, The effect of pressure drop on powder de-agglomeration, Respiratory Drug Delivery Europe 2011, 03-06/05/2011, Davis Healthcare International Publishing, USA, pp. 355-358.

Das, S., Behara, S., Morton, D., Larson, I., Stewart, P., 2011, Total surface energy distributions determined using inverse gas chromatography at finite dilution for understanding the de-agglomeration of lactose powders, Proceedings of Chemeca 2011 - Engineering a better world, 18-21/092011, Engineers Australia, Australia, pp. e1-e10.

Behara, S., Larson, I., Morton, D., Kippax, P., Stewart, P., 2010, Cohesive behaviour of lactose - its influence on aerosolisation under varying air flows, Lactose as a carrier for inhalation products, 26/09 - 28/09/2010, TEFARCO Innova, Italy, pp. 61-62.

Zhou, Q., Armstrong, B., Larson, I., Stewart, P., Morton, D., 2010, Effect of host particle size on the modification of powder flow behaviours for lactose monohydrate following dry coating, Dairy Science and Technology, 15-17/04/2009, Springer France, France, pp. 237-251.

Zhou, Q., Qu, L., Armstrong, B., Larson, I., Stewart, P., Morton, D., 2010, Effect of surface modifaction via mechanical dry coating on the aerosolisattion of a range of milled drug powders, Lactose as a carrier for inhalation products, TEFARCO Innova, Italy, p. 1.

Zhou, Q., Qu, L., Armstrong, B., Larson, I., Stewart, P., Morton, D., 2010, Effect of surface modifaction via mechanical dry coating on the flowability and fluidization of a range of milled lactose powders, Lactose as a carrier for inhalation products, 26/09/2010-28/09/2010, TEFARCO Innova, Italy, p. 1.

Behara, S., Larson, I., Morton, D., Stewart, P., 2010, Effect of time on concentration, de-agglomeration and particle size distributions of aerosol cloud generated by a simple marketed device, Lactose as a carrier for inhalation products, 26/09 - 28/09/2010, University of Parma, Italy, pp. 1-2.

Das, S., Larson, I., Morton, D., Young, P., Stewart, P., 2010, Further understanding of surface energy of lactoses showing different behaviours in formulation, Lactose as a carrier for inhalation products, 26/09 - 28/09/2010, Consortium TEFARCO Innova, BioPharmaNet, University of Parma, Italy, pp. 1-2.

Morton, D., Qu, L., Zhou, Q., Stewart, P., Larson, I., 2010, Improving the flow and dispersion properties of several micronized drug powders using an innovative dry coating approach, World Congress on Particle Technology 6, Nuremberg, Germany, 2010, 26/04/2010, Society of Chemical Industry, Nuremberg, Germany, pp. 1-2.

Morton, D., Larson, I., Phan, S., Ling, C., Das, S., 2010, Mixing strategy and design space of interactive mixtures for use in inhalers, Lactose as a carrier for inhalation products, 26/09 - 28/09/2010, Consortium TEFARCO Innova, BioPharmaNet, Italy, pp. 1-2.

Stewart, P., Morton, D., Zhou, Q., Larson, I., 2010, The influence of dry powder coating methods, including mechanofusion, on the flow properties of inhalable grades of lactose monohydrate., World Congress on Particle Technology 6, Nuremberg, Germany, 2010, 26/04/2010, Society of Chemical Industry, Germany, pp. 1-2.

Larson, I., Morton, D., Stewart, P., Behara, S., 2010, The influence of structure of cohesive binary mixtures on dispersibility behavior under varying flow conditions, World Congress on Particle Technology 6, Nuremberg, Germany, 2010, Society of Chemical Industry, Germany, pp. 1-2.

Morton, D., Stewart, P., Zhou, Q., Larson, I., Das, S., 2010, Understanding the surface energy changes of mechanofused pharmaceutical powders., World Congress on Particle Technology 6, Nuremberg, Germany, 2010, 26/04/2010, Society of Chemical Industry, Germany, pp. 1-2.

Islam, M.N., Stewart, P.J., Larson, I.C., Hartley, P., 2009, Adhesion and dispersion of salmeterol xinafoate from lactose interactive mixtures for inhalation - can surface roughness of carriers determine performance, CHEMECA 2009, 27/09-30/09/2009, Engineers Australia, Australia, pp. 1-10.

Morton, D.A.V., Larson, I.C., Phan, S., Ling, C., Das, S.C., 2009, An investigation of the blending strategy and design space of interactive mixtures for use in inhalers, CHEMECA 2009, 27/09-30/09/2009, Engineers Australia, Australia, p. on line.

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2009, Influence of moisture on surface energy determination by inverse gas chromatography, CHEMECA 2009, 27 September 2009 to 30 September 2009, Engineers Australia, Australia, p. 0.

Dube, A., Larson, I.C., 2009, Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins, 36th Annual Meeting & Exposition of the Controlled Release Society, 18/07-22/07/2009, Controlled Release Society, USA, p. on cd.

Morton, D.A.V., Zhou, Q., Armstrong, B., Larson, I.C., Stewart, P.J., 2009, Surface engineering to improve the flowability and fluidization of a cohesive powder, CHEMECA 2009, 27 September 2009 to 30 September 2009, Engineers Australia, Australia, p. CD.

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2008, Change in surface energy of lactoses after storage at high relative humidity deterined by inverse gas chromatography, Proceedings of Respiratory Drug Delivery, 11 May to 15 May 2008, Virginia Commonwealth University, USA, pp. 645-648.

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2008, The Changes in Dispersion of Salmeterol Xinafoate-lactose Mixtures During Storage at Different Relative Humidities, DDL 19 Proceedings, 11/12/2008-15/12/2008, The Aerosol Society, UK, pp. 128-131.

Das, S.C., Larson, I.C., Stewart, P.J., 2008, The changes in dispersion of salmeterol xinafoate-lactose mixtures during storage at different relative humidities, Proceedings of the Drug Delivery to the Lungs 19 Conference (DDL19), 10/12/2008 - 12/12/2008, DDL, UK, pp. 128-131.

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2007, The relationship between the performance and surface energy of salmeterol xinafoate powders for inhalation during long term storage at different relative humidity, Proceedings of CHEMECA 2007: Academia and Industry Strengthening the Profession, 23 September 2007 to26 September 2007, Engineers Australia, Australia, pp. 468-474.

Islam, M.N., Stewart, P.J., Larson, I.C., Hartley, P., 2006, Measurement of surface roughness of lactose powders by AFM and confocal microscopy, 33rd Australasian Chemical Engineering conference, 17 September 2006 to 20 September 2006, Institute of Chemical Engineers, Auckland NZ, pp. 1-6.

Adi, H., Larson, I.C., Stewart, P.J., 2005, Fractionation of narrow particle size distributions of micronised lactose by milling and wet sieving techniques, Chemeca 2005, 25/09/2005 to 28/09/2005, Institute of Chemical Engineers, Australia, pp. 1-6.

Adi, H., Larson, I.C., Stewart, P.J., 2005, Influence of cohesive properties of micronised lactose powders on particle size analysis by laser diffraction, CHEMECA 2005, 25 September 2005 to 28 September 2005, Institution of Chemical Engineers, IChemE, SCENZ, RACI, Australia, pp. 1-6.

Jones, K.M., Larson, I.C., Weaver, D., Caliph, S.M., 2005, The adventures of Trev the tablet: replacing practical classes and lectures using an online game scenario, Proceedings of the Australasian Society for Computers in Learning in Tertiary Education Conference, 04 December 2005 to 07 December 2005, AJET, Brisbane Qld Australia, pp. 309-312.

Adi, H., Larson, I.C., Stewart, P.J., 2004, Influence of particle size of the fine lactose in the dispersion of salmeterol xinafoate from lactose mixtures for inhalation, Respiratory Drug Delivery, 25 April 2004 to 29 April 2004, Davis Healthcare International Publishing, River Grove USA, pp. 553-556.

Other

Das, S.C., Larson, I.C., Young, P.M., Stewart, P.J., 2008, Investigation into the mechanism of dispersibility changes of salmeterol xinafoate powders for inhalation using a spraytec, Poster Presentation as listed in the APSA 2008: Handbook, APSA, Australia.

Dong, C.Y., Boyd, B.J., Larson, I.C., 2007, Agrochemical composition comprising liquid crystal particles, United States of America.

Teaching Commitment

Developer of Pharmatopia – a collaborative virtual world learning tool

Second Year Colloid Chemistry

Third year Formulation Chemistry

Major teaching expertise: colloid and surface chemistry, polymer chemistry, formulation chemistry

Activities

Affiliations with institutes

Drug Delivery, Disposition and Dynamics
Monash Institute of Pharmaceutical Sciences

Awards

Academic awards (national, international)

2010
Vice Chancellor's Award for Teaching Excellence
Monash University

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(MASTER'S BY RESEARCH).

Thesis Title:

Formulation and optimation nanotechnology for inhalations drug delivery.

Supervisors:

Larson, I (Main).

Program of Study:

(MASTER'S BY RESEARCH).

Thesis Title:

Insight into de-agglomeration of mechanofused salbutamol sulphate powders for inhalation.

Supervisors:

Stewart, P (Main), Larson, I (Associate), Morton, D (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Surface Examination of Engineered Particles and the Correlation to their Bulk Properties.

Supervisors:

Morton, D (Main), Larson, I (Joint).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Understanding Rapid Structural Transformations in Solid State Pharmaceutical Systems.

Supervisors:

Boyd, B (Main), Larson, I (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Understanding how powders for inhalation work.

Supervisors:

Larson, I (Main).

Completed Supervision

Student:

Adi, H.

Program of Study:

Understanding the role of fine excipients on the dispersion of salmeterol xinafoate from powder mixtures for inhalation. (PHD) 2006.

Supervisors:

Stewart, P (Main), Larson, I (Associate).

Student:

Behara, S.

Program of Study:

Insight into mechanisms of de-agglomeration of pharmaceutical powders for inhalation. (PHD) 2011.

Supervisors:

Larson, I (Joint), Stewart, P (Joint-Co), Morton, D (Associate).

Student:

Das, S.

Program of Study:

Understanding the changes in dispersion of salmeterol xinafoate-lactose mixtures during storage at different relative humidities. (PHD) 2008.

Supervisors:

Stewart, P (Main), Larson, I (Associate).

Student:

Dong, Y.

Program of Study:

Investigation of nanostructured liquid crystal particles as novel agrochemical delivery agents. (PHD) 2009.

Supervisors:

Larson, I (Main), Boyd, B (Associate).

Student:

Dube, A.

Program of Study:

Assessment of the impact of biopolymeric nanoparticles on the oral absorption of green tea catechins. (PHD) 2010.

Supervisors:

Larson, I (Joint-Co), Nicolazzo, J (Joint).

Student:

Heinicke, I.

Program of Study:

The role of capillary forces in the dispersion of dry powder interactive mixtures. (Masters) 2007.

Supervisors:

Larson, I (Main), Stewart, P (Associate).

Student:

Islam, M.

Program of Study:

THE INFLUENCE OF SURFACE CHARACTERISTICS OF LACTOSE CARRIERS ON THE RESPIRATORY DELIVERY OF SALMETEROL XINAFOATE FROM INTERACTIVE MIXTURES. (PHD) 2004.

Supervisors:

Stewart, P (Main), Larson, I (Associate).

Student:

Nguyen, T.

Program of Study:

Investigation of novel liquid crystalline materials for the sustained oral delivery of poorly water soluble drugs. (PHD) 2008.

Supervisors:

Boyd, B (Main), Larson, I (Associate), Porter, C (Associate).

Student:

Soon, R.

Program of Study:

Investigation of the surface of colistin-susceptible and resistant Acinetobacter baumannii. (PHD) 2011.

Supervisors:

Nation, R (Main), Larson, I (Associate), Li, J (Associate).

Student:

Zhou, Q.

Program of Study:

Surface modification of pharmaceutical powders. (PHD) 2011.

Supervisors:

Morton, D (Joint), Stewart, P (Joint-Co), Larson, I (Associate).