Dr Richard Prankerd - Researcher Profile

Biography

Position

Senior Lecturer
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Delivery, Disposition and Dynamics
Monash Institute of Pharmaceutical Sciences

Qualifications

PHARMACEUTICAL CHEMISTRY

Institution: University of Otago

Year awarded: 1985

PHARMACEUTICAL CHEMISTRY

Institution: University of Otago

Year awarded: 1977

PHARMACY

Institution: University of Otago

Year awarded: 1974

Publications

Books

Prankerd, R.J., 2007, Volume 33; Critical Compilation of pKa Values for Pharmaceutical Substances, Elsevier, USA.

Journal Articles

Wallace, S.J., Li, J., Nation, R.L., Prankerd, R.J., Boyd, B.J., 2012, Interaction of colistin and colistin methanesulfonate with liposomes: colloidal aspects and implications for formulation, Journal of Pharmaceutical Sciences [P], vol 101, issue 9, John Wiley & Sons, USA, pp. 3347-3359.

Summerhayes, R., Chan, M., Ignjatovic, V., Prankerd, R., Monagle, P., 2011, Stability and sterility of diluted enoxaparin under three different storage conditions, Journal of Paediatrics and Child Health [E], vol 47, issue 5, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 299-301.

McIntosh, M.P., Leong, N., Katneni, K., Morizzi, J., Shackleford, D.M., Prankerd, R.J., 2010, Impact of chlorpromazine self-association on its apparent binding constants with cyclodextrins: Effect of SBE7-beta-CD on the disposition of chlorpromazine in the rat, Journal of Pharmaceutical Sciences [P], vol 99, issue 7, John Wiley & Sons, Inc., USA, pp. 2999-3008.

Wallace, S.J., Li, J., Nation, R.L., Prankerd, R.J., Velkov, T., Boyd, B.J., 2010, Self-assembly behavior of colistin and its prodrug colistin methanesulfonate: implications for solution stability and solubilization, Journal of Physical Chemistry B [P], vol 114, American Chemical Society, USA, pp. 4836-4840.

Creek, D.J., Ryan, E., Charman, W.N., Chiu, F.C.K., Prankerd, R., Vennerstrom, J., Charman, S.A., 2009, Stability of peroxide antimalarials in the presence of human hemoglobin, Antimicrobial Agents And Chemotherapy [P], vol 53, issue 8, American Society for Microbiology, USA, pp. 3496-3500.

velkov, T., Lim, M.L., Capuano, B., Prankerd, R.J., 2008, A protocol for the combined sub-fractionation and delipidation of lipid binding proteins using hydrophobic interaction chromatography, JOURNAL OF CHROMATOGRAPHY. B, ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, vol 867, issue 2, ELSEVIER SCIENCE BV, NETHERLANDS, pp. 238-246.

Tarwadi, T., Jazayeri, J., Prankerd, R., Pouton, C.W., 2008, Preparation and in vitro evaluation of novel lipopeptide transfection agents for efficient gene delivery, Bioconjugate Chemistry, vol 19, issue 4, American Chemical Society, USA, pp. 940-950.

Creek, D.J., Charman, W.N., Chiu, F.C.K., Prankerd, R.J., Dong, Y., Vennerstrom, J., Charman, S.A., 2008, Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials, Antimicrobial Agents and Chemotherapy, vol 52, issue 4, The American Society for Microbiology, USA, pp. 1291-1296.

Creek, D.J., Charman, W.N., Chiu, F.C.K., Prankerd, R.J., McCullough, K.J., Dong, Y., Vennerstrom, J., Charman, S.A., 2007, Iron-mediated degradation kinetics of substituted dispiro-1,2,4-trioxolane antimalarials, Journal of Pharmaceutical Sciences, vol 96, issue 11, Wiley-Liss Inc, New Jersey, United States, pp. 2945-2956.

Horne, H.J., d'Auvergne, E.J., Coles, M., Velkov, T., Chin, Y., Charman, W.N., Prankerd, R.J., Gooley, P., Scanlon, M., 2007, Probing the Flexibility of the DsbA Oxidoreductase from Vibrio cholerae-a 15N - 1H Heteronuclear NMR Relaxation Analysis of Oxidized and Reduced Forms of DsbA, Journal of Molecular Biology, vol 371, issue 3, Academic Press, England, pp. 703-716.

Charman, S.A., Perry, C.S., Chiu, F.C.K., McIntosh, K.A., Prankerd, R.J., Charman, W.N., 2006, Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin, Journal of Pharmaceutical Sciences, vol 95, issue 2, John Wiley & Sons Inc., USA, pp. 256-267.

Perry, C.S., Charman, S.A., Prankerd, R.J., Chiu, F.C.K., Dong, Y., Vennerstrom, J.L., Charman, W.N., 2006, Chemical kinetics and aqueous degradation pathways of a new class of synthetic ozonide antimalarials, Journal of Pharmaceutical Sciences, vol 95, issue 4, John Wiley & Sons, Inc., USA, pp. 737-747.

Nisbet, D.R., Crompton, K.E., Hamilton, S.D., Shirakawa, S., Prankerd, R.J., Finkelstein, D.I., Horne, M.K., Forsythe, J.S., 2006, Morphology and gelation of thermosensitive xyloglucan hydrogels, Biophysical Chemistry, vol 121, issue 1, Elsevier, The Netherlands, pp. 14-20.

Perry, C.S., Charman, S.A., Prankerd, R.J., Chiu, F.C.K., Scanlon, M.J., Chalmers, D.K., Charman, W.N., 2006, The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins, Journal of Pharmaceutical Sciences, vol 95, issue 1, John Wiley & Sons, Inc., USA, pp. 146-158.

Velkov, T., Chuang, S., Prankerd, R.J., Sakellaris, H.H., Porter, C.J.H., Scanlon, M.J., 2005, An improved method for the purification of rat liver-type fatty acid binding protein from Escherichia coli, Protein Expression & Purification, vol 44, issue 1, Academic Press, USA, pp. 23-31.

Creek, D.J., Chiu, F.C.K., Prankerd, R.J., Charman, S.A., Charman, W.N., 2005, Kinetics of iron-mediated artemisinin degradation: effect of solvent composition and iron salt, Journal of Pharmaceutical Sciences, vol 94, issue 8, John Wiley & Sons, Inc., USA, pp. 1820-1829.

Crompton, K.E., Prankerd, R.J., Paganin, D.M., Scott, T.F., Horne, M.K., Finkelstein, D.I., Gross, K.A., Forsythe, J.S., 2005, Morphology and gelation of thermosensitive chitosan hydrogels, Biophysical Chemistry, vol 117, issue 1, Elsevier, The Netherlands, pp. 47-53.

Campbell, M., Prankerd, R.J., Davie, A.S., Charman, W.N., 2004, Degradation of berenil (diminazene aceturate) in acidic aqueous solution, Journal of Pharmacy and Pharmacology, vol 56, issue 10, Pharmaceutical Press, London UK, pp. 1327-1332.

Taillardat-Bertschinger, A., Perry, C.S., Galland, A., Prankerd, R.J., Charman, W.N., 2003, Partitioning of halofantrine hydrochloride between water, micellar solutions, and soybean oil: effects on its apparent ionization constant, Journal of Pharmaceutical Sciences, vol 92, issue 11, John Wiley & Sons, Inc., USA, pp. 2217-2228.

Shackleford, D.M., Prankerd, R.J., Scanlon, M.J., Charman, W.N., 2003, Self-micellization of gemfibrozil 1-0- acyl glucuronide in aqueous solution, Pharmaceutical Research, vol 20, issue 3, Kluwer Academic/Plenum Publishers, USA, pp. 465-470.

Khoo, S.M., Prankerd, R.J., Edwards, G.A., Porter, C., Charman, W.N., 2002, A physicochemical basis for the extensive intestinal lymphatic transport of a poorly lipid soluble antimalarial, halofantrine hydrochloride, after postprandial administration to dogs, Journal of Pharmaceutical Sciences, vol 91, issue 3, John Wiley and Sons Inc., USA, pp. 647-659.

Conference Proceedings

Sou, T., Nassta, G., Kaminskas, L., McIntosh, M., Prankerd, R., Orlando, L., Morton, D., 2011, Particle engineering of a mannitol-based powder formulation for delivery of biomolecules to the lung, Drug Delivery to the Lungs 22, 07-09/12/2011, The Aerosol Society, England, pp. 52-55.

Morton, D., McIntosh, M., Olerile, L., Prankerd, R., 2011, Probing the role of self-assembly in spray dried powder formulations, Respiratory Drug Delivery 2011, 03-06/05/2011, RDD Online and Aptar Pharma, USA, pp. 363-366.

Warren, D., Prankerd, R.J., Pouton, C.W., 2003, Phase behaviour determination of aqueous bile salt / phospholipid systems using isothermal titration micro-calorimetry, Proceedings of the APSA: Integrating Research into Practice, Australasian Pharmaceutical Science Association, Sydney NSW Australia.

Teaching Commitment

Physical and pharmaceutical chemistry

Formulation chemistry

Drug stability

Activities

Affiliations with institutes

Drug Delivery, Disposition and Dynamics
Monash Institute of Pharmaceutical Sciences

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Development of a dry powder containing oxytocin suitable for inhalation for the treatment of postpartum haemorrhage.

Supervisors:

Mcintosh, M (Main), Morton, D (Associate), Orlando, L (Associate), Prankerd, R (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Dry Powder Formulation for Pulmonary Delivery of Peptides.

Supervisors:

Mcintosh, M (Main), Prankerd, R (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Physicochemical properties, permeability & formulation of geraniin essential for its oral absorption.

Supervisors:

Palanisamy, U (Main), Prankerd, R (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Structural effects on the acid-base behaviour of drugs.

Supervisors:

Prankerd, R (Main), Boyd, B (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

TBA.

Supervisors:

Prankerd, R (Main), Boyd, B (Associate).

Completed Supervision

Student:

Ben-Nwauzor, U.

Program of Study:

PHYSIOCHEMICAL CHARACTERIZATION OF A NOVEL PLANT POLYSACCHARIDE AND ITS PHARMACEUTICAL APPLICATIONS. (PHD) 2004.

Supervisors:

Prankerd, R (Main).

Student:

Elendran, S.

Program of Study:

. 2012.

Supervisors:

Palanisamy, U (Main), Lee, W (Associate), Prankerd, R (Associate).

Student:

Roberts, B.

Program of Study:

A physicochemical investigation of novel lipopeptide-based non-viral transfection agents. (Masters) 2009.

Supervisors:

Prankerd, R (Main), Pouton, C (Associate).