Tel: +61 3 990 39747
Fax: +61 3 990 39052
Email: maria.koltun@monash.edu
Web: http://www.pharm.monash.edu.au/research/mips/cdco/index.html
Position
Research Scientist
Faculty of Pharmacy and Pharmaceutical Sciences
Centre for Drug Candidate Optimisation
Monash Institute of Pharmaceutical Sciences
Coteron, J., Marco, M., Esquivias, J., Deng, X., White, K., White, J., Koltun, M., El Mazouni, F., Kokkonda, S., Katneni, K., Bhamidipati, R., Shackleford, D., Angulo-Barturen, I., Ferrer, S., Jimenez-Diaz, M., Gamo, F., Goldsmith, E., Charman, W., Bathurst, I., Floyd, D., Matthews, D., Burrows, J., Rathod, P., Charman, S., Phillips, M., 2011, Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential, Journal of Medicinal Chemistry [P], vol 54, issue 15, American Chemical Society, USA, pp. 5540-5561.
Koltun, M., Morizzi, J., Katneni, K., Charman, S.A., Shackleford, D., McIntosh, M.P., 2010, Preclinical comparison of intravenous melphalan pharmacokinetics administered in formulations containing either (SBE)7m-beta-cyclodextrin or a co-solvent system, Biopharmaceutics and Drug Disposition [E], vol 31, issue 8-9, John Wiley & Sons, Ltd, online, pp. 450-454.
Dong, Y., Wittlin, S., Sriraghavan, K., Chollet, J., Charman, S.A., Charman, W.N., Scheurer, C., Urwyler, H., Santo Tomas, J., Christopher Snyder, Creek, D.J., Morizzi, J., Koltun, M., Matile, H., Wang, X., Padmanilayam, M., Tang, Y., Dorn, A., Brun, R., Vennerstrom, J., 2010, The structure - activity relationship of the antimalarial ozonide arterolane (OZ277), Journal of Medicinal Chemistry [P], vol 53, American Chemical Society, USA, pp. 481-491.
Koltun, M., Nikolovski, J., Strong, K., Nikolic-Paterson, D.J., Comper, W.D., 2005, Mechanism of hypoalbuminemia in rodents, American Journal of Physiology: Heart and Circulatory Physiology, vol 288, issue 4, American Physiological Society, USA, pp. H1604-H1610.
Koltun, M., Comper, W.D., 2004, Retention of albumin in the circulation is governed by saturable renal cell-mediated processes, Microcirculation, vol 11, issue 4, Taylor & Francis Inc, Philadelphia USA, pp. 351-360.
Affiliations with institutes
Centre for Drug Candidate Optimisation
Monash Institute of Pharmaceutical Sciences
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