Dr Georg Ramm - Researcher Profile

Biography

Georg works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Senior Research Fellow.

Qualifications

PHD CELL BIOLOGY

Institution: Utrecht University

Year awarded: 2000

DIPLOMA OF BIOCHEMISTRY

Institution: Martin Luther University

Year awarded: 1995

Publications

Journal Articles

Ruwanpura, S., McLeod, L., Miller, A., Jones, J., Vlahos, R., Ramm, G., Longano, A., Bardin, P., Bozinovski, S., Anderson, G., Jenkins, B., 2012, Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice, American Journal Of Physiology-Lung Cellular And Molecular Physiology [P], vol 32, issue 7, American Physiological Society, Untied States, pp. L627-L639.

Klionsky, D.J., Abdalla, F.C., Abeliovich, H., Abraham, R.T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J.A., Ahn, H., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H.M., Al-Zeer, M.A., Albert, M.L., Albin, R.L., Alegre-Abarrategui, J., Aleo, M.F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A.O., Andrieu-Abadie, N., Anantharaman, V., Ann, D.K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J.P., Asanuma, K., Asare, N.Y., Ashida, H., Askanas, V., Askew, D.S., Auberger, P., Devenish, R.J., Mijaljica, D., Prescott, M., Ramm, G., Zuckerbraun, B., 2012, Guidelines for the use and interpretation of assays for monitoring autophage, Autophagy [P], vol 8, issue 43, Landes Bioscience, USA, pp. 445-544.

Gong, L., Ramm, G., Devenish, R.J., Prescott, M., 2012, HcRed, a genetically encoded fluorescent binary cross-linking agent for cross-linking of mitochondrial ATP synthase in Saccharomyces cerevisiae, PLoS ONE [P], vol 7, issue 4 (Art. ID: e35095), Public Library of Science, USA, pp. 1-7.

Tan, S., Ng, Y., Burchfield, J.G., Ramm, G., Lambright, D.G., Stockli, J., James, D.E., 2012, The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes, Molecular and Cellular Biology [P], vol 32, issue 24, American Society for Microbiology, USA, pp. 4946-4959.

Anwari, K., Webb, C.T., Poggio, S., Perry, A.J., Belousoff, M.j., Celik, N., Ramm, G., Lovering, A., Sockett, R.E., Smit, J., Jacobs-Wagner, C., Lithgow, T.J., 2012, The evolution of new lipoprotein subunits of the bacterial outer membrane BAM complex, Molecular Microbiology [P], vol 84, issue 5, Wiley-Blackwell Publishing Ltd, UK, pp. 832-844.

Uwamahoro, N., Qu, Y., Jelicic, B., Lo, T., Beaurepaire, C., Bantun, F., Quenault, T., Boag, P., Ramm, G., Callaghan, J.M., Beilharz, T.H., Nantel, A., Peleg, A.Y., Traven, A., 2012, The functions of mediator in Candida albicans support a role in shaping species-specific gene expression, Plos Genetics [P], vol 8, issue 4 (Art. ID: e1002613), Publc Library of Science, USA, pp. 1-18.

Bach, M., Ramm, G., 2011, How to control self-eating habits: Metabolic control of autophagy, Australian Biochemist [P], vol 42, issue 2, Manning Print Solutions, Australia, pp. 17-20.

D'Cruze, T., Gong, L., Treerat, P., Ramm, G., Boyce, J., Prescott, M., Adler, B., Devenish, R., 2011, Role for the Burkholderia pseudomallei Type Three Secretion System Cluster 1 bpscN gne in vrulence, Infection And Immunity [P], vol 79, issue 9, American Society for Microbiology, USA, pp. 3659-3664.

Gong, L., Cullinane, M., Treerat, P., Ramm, G., Prescott, M., Adler, B., Boyce, J.D., Devenish, R.J., 2011, The Burkholderia pseudomallei type III secretion system and BopA are required for evasion of LC3-associated phagocytosis, PLoS ONE [P], vol 6, issue 3 (Art. No: e17852), Public Library of Science, USA, pp. 1-11.

Bach, M., Larance, M., James, D., Ramm, G., 2011, The serine/threonine kinase ULK1 is a target of multiple phosphorylation events, Biochemical Journal [P], vol 440, issue 2, Portland Press Ltd, UK, pp. 283-291.

Ng, Y., Ramm, G., Burchfield, J.G., Coster, A.C., Stockli, J., James, D.E., 2010, Cluster analysis of insulin action in adipocytes reveals a key role for Akt at the plasma membrane, Journal Of Biological Chemistry [P], vol 285, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 2245-2257.

Ng, Y., Ramm, G., James, D.E., 2010, Dissecting the mechanism of insulin resistance using a novel heterodimerization strategy to activate AKT, Journal Of Biological Chemistry [P], vol 285, American Society for Biochemistry & Molecular Biology Inc, USA, pp. 5232-5239.

Yip, M., Ramm, G., Larance, M., Hoehn, K.L., Wagner, M.C., Guilhaus, M., James, D.E., 2008, CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes, Cell Metabolism [P], vol 8, issue 5, Cell Press, USA, pp. 384-398.

Ng, Y., Ramm, G., Lopez, J., James, D.E., 2008, Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes, Cell Metabolism [P], vol 7, issue 4, Cell Press, USA, pp. 348-356.

Stockli, J., Davey, J., Hohnen-Behrens, C., Xu, A., James, D.E., Ramm, G., 2008, Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association, Molecular Endocrinology [P], vol 22, issue 12, The Endocrine Society, USA, pp. 2703-2715.

Larance, M., Ramm, G., James, D.E., 2008, The GLUT4 code, Molecular Endocrinology [P], vol 22, issue 2, The Endocrine Society, USA, pp. 226-233.

Ramm, G., Larance, M., Guilhaus, M., James, D.E., 2006, A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160, Journal Of Biological Chemistry [P], vol 281, issue 39, American Society for Biochemistry & Molecular Biology Inc, USA, pp. 29174-29180.

Carey, A.L., Steinberg, G.R., Macaulay, S.L., Thomas, W., Holmes, A., Ramm, G., Prelovsek, O., Hohnens-Behrens, C., Watt, M.J., James, D., Kemp, B.E., Pedersen, B., Febbraio, M.A., 2006, Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase, Diabetes, vol 55, issue 10, American Diabetes Association, USA, pp. 2688-2697.

Thomas, E.C., Zhe, Y., Molero, J., Schmitz-Peiffer, C., Ramm, G., James, D.E., Whitehead, J.P., 2006, The subcellular fractionation properties and function of insulin receptor substrate-1 (IRS-1) are independent of cytoskeletal integrity, International Journal of Biochemistry and Cell Biology [P], vol 38, issue 10, Pergamon, UK, pp. 1686-1699.

Larance, M., Ramm, G., Stockli, J., van Dam, E.M., Winata, S., Wasinger, V., Simpson, F., Graham, M., Junutula, J.R., Guilhaus, M., James, D.E., 2005, Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking, Journal Of Biological Chemistry [P], vol 280, issue 45, American Society for Biochemistry & Molecular Biology Inc, USA, pp. 37803-37813.

Ramm, G., James, D.E., 2005, GLUT4 trafficking in a test tube, Cell Metabolism [P], vol 2, issue 3, Cell Press, USA, pp. 150-152.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The spatiotemporal characterisation of signalling pathways in mammalian mitophagy.

Supervisors:

Ramm, G (Main), Prescott, M (Associate).