Dr Martin Tymms - Researcher Profile

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Address

Monash Institute of Medical Research
Monash Medical Centre, Clayton

Biography

Martin works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Senior Research Fellow.

Qualifications

PHD
Institution: Monash University
Year awarded: 1980
BACHELOR OF SCIENCE (HONS)
Institution: Monash University
Year awarded: 1975

Publications

Book Chapters

Thomas, R.S., Ng, A.Y.N., Zhou, J., Tymms, M.J., Doppler, W., Kola, I., 2000, The elf group of ets-related transription factors, in Biology of the mammary gland, Kluwer Academic/Plenum Publishers, New York NY USA, pp. 123-128.

Journal Articles

Conway, T., Wazny, J., Bromage, A., Tymms, M.J., Sooraj (Sreedharan), D., Williams, E., Beresford-Smith, B., 2012, Xenome--a tool for classifying reads from xenograft samples, Bioinformatics [P], vol 28, issue 12, Oxford University Press, United Kingdom, pp. 172-178.

Hasthorpe, S., Tainton, K., Peart, M., Roeszler, K., Bell, K., Lusby, P., Hutson, J., Tymms, M., 2007, G2/M checkpoint gene expression in developing germ cells, Molecular Reproduction And Development [P], vol 74, issue 5, John Wiley & Sons, Inc., United States, pp. 531-538.

Wolvetang, E.J., Bradfield, O.M., Tymms, M.J., Zavarsek, S., Hatzistavrou, T., Kola, I., Hertzog, P.J., 2003, The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: Implications for Down syndrome, Biochimica et Biophysica Acta, vol 1628, issue 2, Elsevier Science BV, Amsterdam The Netherlands, pp. 105-110.

Zhou, J., Ng, A.Y., Tymms, M.J., Jermiin, L.S., Seth, A., Kola, I., Thomas, R.S., 1998, A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement inhuman carcinoma cell lines, Oncogene, vol 17, Stockton Press, UK, pp. 2719-2732.

McKinlay, L.H., Tymms, M.J., Thomas, R.S., Seth, A., Hasthorpe, S., Hertzog, P.J., Kola, I., 1998, The Role of Ets-1 in Mast Cell Granulocyte-Macrophage Colony-Stimulating Factor Expression and Activation, The Journal of Immunology, vol 161, The American Association of Immunologists, USA, pp. 4099-4105.

Tymms, M.J., Ng, A.Y., Thomas, R.S., Schutte, B.C., Zhou, J., Eyre, H.J., Sutherland, G.R., Seth, A., Rosenberg, M., Papas, T., Debouck, C., Kola, I., 1997, A novel epethelial-expressed ETS gene, ELF-3: Human and murine cDNA sequences, murine genomic organisation, human mapping to 1q32.2, and expression in tissues and cancer, Oncogene, vol 15, Stockton Press, UK, pp. 2449-2462.

Holland, K.A., Owczarek, C.M., Hwang, S.Y., Tymms, M.J., Constantinescu, S., Pfeffer, L.M., Kola, I., Hertzog, P.J., 1997, A type I interferon signaling factor, ISF21, encoded on chromosome 21 is distinct from receptor components and their down-regulation and is necessary for transcritpional activation of interferon-regulated genes, Jouirnal of Biological Chemistry, vol 272, American Soc for Biochemistry & Molecular Biology, USA, pp. 21045-21051.

Thomas, R.S., Tymms, M.J., McKinlay, L.H., Shannon, M.F., Seth, A., Kola, I., 1997, ETS1, NFkB and API synergistically transactivate the human GM-CSF promoter, Oncogene, vol 14, Stockton Press, UK, pp. 2845-2855.

Iannello, R., Young, J., Sumarsono, S.H., Tymms, M.J., Dahl, H.M., Gould, J., Hedger, M., Kola, I., 1997, Regulation of Pdha-2 Expression is mediated byproximal promoter sequences and CpG Methylation, Molecular and Cellular Biology, vol 17, American Society for Microbiology, Washington DC USA, pp. 612-617.

Conference Proceedings

Zhou, J., Ng, A.Y., Thomas, R.S., Tymms, M.J., Kola, I., 1998, A novel ETS transcription factor, ELF5, is related to the epithelium-specific ETS factor, ELF3, 10th Lorne Cancer Conference, Lorne Vic, 12-15 February 1998, Australian Cancer Society, Vic Australia, p. 424.

Ng, A.Y., Thomas, R.S., Tymms, M.J., Zhou, J., Hertzog, P.J., Kola, I., 1998, ELF3, a new member of the ETS family of transcription factors, is epithelial expressed and maps to 1q32.2, a region frequently amplified in breast cancer, Functional Genomics: New Horizons in Genetics and Disease, Melbourne, Australia. March 15-17, 1998, SmithKline Beecham Pharmaceuticals, Melbourne Vic Australia.

Other

Kola, I., Tymms, M.J., Debouck, C., 1997, A novel ets human family member, elf3gene, in epithelial cancers, USA Europe Japan.

Kola, I., Tymms, M.J., McKinlay, L.H., 1997, Modulation of haemopoietic cell activity and inflammation via the Ets-1 gene and agents useful for same, Australia.