Dr David Hoke - Researcher Profile

Biography

David works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

BIOCHEMISTRY

Institution: The University of Texas

Year awarded: 1999

BIOCHEMISTRY

Institution: Texas A&M University

Year awarded: 1993

Publications

Journal Articles

Hatfaludi, T.Z., Al-Hasani, K., Gong, L., Boyce, J.D., Ford, M., Wilkie, I.W., Quinsey, N.S., Dunstone, M.A., Hoke, D.E., Adler, B., 2012, Screening of 71 P. multocida proteins for protective efficacy in a fowl cholera infection model and characterization of the protective antigen PlpE, PLoS ONE [P], vol 7, issue 7 (Art. ID: e39973), Public Library of Science, USA, pp. 1-11.

Jayakrishnan, B., Hoke, D.E., Langendorf, C.G., Buckle, A.M., Rowley, M.J., 2011, An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes, PLoS ONE [P], vol 6, issue 4 (Art. No: e18411), Public Library of Science, USA, pp. 1-6.

Srikram, A., Zhang, K., Bartpho, T., Lo, M., Hoke, D., Sermswan, R., Adler, B., Murray, G., 2011, Cross-protective immunity against leptospirosis elicited by a live, attenuated lipopolysaccharide mutant, Journal of Infectious Diseases [E], vol 203, issue 6, Oxford University Press, USA, pp. 870-879.

Ho, M., Hoke, D.E., Chua, Y., Li, Q., Culvenor, J.G., Masters, C., White, A.R., Evin, G., 2011, Effect of metal chelators on gamma-secretase indicates that calcium and magnesium ions facilitate cleavage of Alzheimer amyloid precursor substrate, International Journal of Alzheimer's Disease [E], vol 2011, issue Art. No: 950932, Hindawi Publishing Corporation, USA, pp. 1-10.

Hoke, D.E., Zhang, K., Egan, S., Hatfaludi, T.Z., Buckle, A.M., Adler, B., 2011, Membrane proteins of Pseudoalteromonas tunicata during the transition from planktonic to extracellular matrix-adherent state, Environmental Microbiology Reports [E], vol 3, issue 3, Wiley-Blackwell Publishing Ltd, UK, pp. 405-413.

Lawson, V.A., Lumicisi, B., Welton, J., Machalek, D., Gouramanis, K., Klemm, H.M., Stewart, J.D., Masters, C.L., Hoke, D.E., Collins, S.J., Hill, A.F., 2010, Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein, PLoS ONE [P], vol 5, issue 8, Public Library of Science, US, pp. 1-9.

Witchell, T., Hoke, D., Bulach, D., Coutts, S., Driesen, S., Cordwell, S., Adler, B., 2010, The major surface Vsp proteins of Brachyspira hyodysenteriae form antigenic protein complexes, Veterinary Microbiology [P], vol 149, Elsevier BV, The Netherlands, pp. 157-162.

Vivian, J., Beddoe, T.C., McAlister, A.D., Wilce, M.C.J., Zaker-Tabrizi, L., Troy, S.T., Byres, E., Hoke, D.E., Cullen, P.A., Lo, M., Murray, G.L., Adler, B., Rossjohn, J., 2009, Crystal structure of LipL32, the most abundant surface protein of pathogenic Leptospira spp., Journal of Molecular Biology, vol 387, issue 5, Academic Press, UK, pp. 1229-1238.

Murray, G.L., Srikram, A., Hoke, D.E., Wunder Jr., E.A., Henry, R.M., Lo, M., Zhang, K., Sermswan, R.W., Ko, A.I., Adler, B., 2009, Major surface protein LipL32 is not required for either acute or chronic infection with Leptospira interrogans, Infection and Immunity, vol 77, issue 3, American Society for Microbiology, United States, pp. 952-958.

Hoke, D.E., Egan, S., Cullen, P.A., Adler, B., 2008, LipL32 is an extracellular matrix-interacting protein of Leptospira spp. and Pseudoalteromonas tunicata, Infection and Immunity, vol 76, issue 5, American Society for Microbiology, United States, pp. 2063-2069.

White, A.R., Du, T., Laughton, K.M., Volitakis, I., Sharples, R.A., Xilinas, M.E., Hoke, D.E., Damian Holsinger, R.M., Evin, G., Cherny, R.A., Hill, A.F., Barnham, K.J., Li, Q., Bush, A.I., Masters, C.L., 2006, Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity, The Journal of Biological Chemistry, vol 281, issue 26, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 17670-17680.

Hoke, D.E., Tan, J., Ilaya, N.T., Culvenor, J.G., Smith, S.J., White, A.R., Masters, C.L., Evin, G., 2005, In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc, FEBS Journal, vol 272, issue 21, Blackwell Publishing, Oxford England, pp. 5544-5557.

Evin, G., Canterford, L., Hoke, D.E., Sharples, R.A., Culvenor, J.G., Masters, C.L., 2005, Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex, Biochemistry, vol 44, issue 11, American Chemical Society, Washington USA, pp. 4332-4341.

Culvenor, J.G., Ilaya, N.T., Ryan, M.T., Canterford, L., Hoke, D.E., Williamson, N.A., McLean, C.A., Masters, C.L., Evin, G., 2004, Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations, European Journal of Biochemistry, vol 271, issue 2, Elsevier Science BV, Amsterdam The Netherlands, pp. 375-385.

Hoke, D.E., Carson, D.D., Hook, M., 2003, A heparin binding synthetic peptide from human HIP / RPL29 fails to specifically differentiate between anticoagulantly active and inactive species of heparin, Journal of Negative Results in Biomedicine, vol 2, issue 1, BioMed Central Ltd, UK, pp. 1-10.

Kirn-Safran, C.B., Julian, J., Fongemie, J.E., Hoke, D.E., Czymmek, K.J., Carson, D.D., 2002, Changes in the cytologic distribution of heparin/heparan sulfate interacting protein/ribosomal protein L29 (HIP/RPL29) during in vivo and in vitro mouse mammary epithelial cell expression and differentiation, Developmental Dynamics, vol 223, issue 1, Wiley-Liss, Div. John Wiley & Sons, Inc., Hoboken USA, pp. 70-84.