Dr Noelene Quinsey - Researcher Profile

Biography

Noelene works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: University of Melbourne

Year awarded: 1998

BACHELOR OF SCIENCE(HONS)

Institution: University of Melbourne

Year awarded: 1994

Publications

Journal Articles

Murray, G.L., Lo, M., Bulach, D.M., Srikram, A., Seemann, T., Quinsey, N.S., Sermswan, R., Allen, A., Adler, B., 2013, Evaluation of 238 antigens of Leptospira borgpetersenii serovar Hardjo for protection against kidney colonisation, Vaccine [P], vol 31, issue 3, Elsevier Ltd, UK, pp. 495-499.

Yan, X., Porter, C.J., Hardy, S.P., Steer, D.L., Smith, A.I., Quinsey, N.S., Hughes, V.A., Cheung, K.J., Keyburn, A., Kaldhusdal, M., Moore, R., Bannam, T.L., Whisstock, J., Rood, J.I., 2013, Structural and Functional Analysis of the Pore-Forming Toxin NetB from Clostridium perfringens, mBio [E], vol 4, issue 1, American Society for Microbiology, USA, pp. 1-9.

Hatfaludi, T.Z., Al-Hasani, K., Gong, L., Boyce, J.D., Ford, M., Wilkie, I.W., Quinsey, N.S., Dunstone, M.A., Hoke, D.E., Adler, B., 2012, Screening of 71 P. multocida proteins for protective efficacy in a fowl cholera infection model and characterization of the protective antigen PlpE, PLoS ONE [P], vol 7, issue 7 (Art. ID: e39973), Public Library of Science, USA, pp. 1-11.

Bantwal, R., Bannam, T.L., Porter, C.J., Quinsey, N.S., Lyras, D., Adams, V.M., Rood, J.I., 2012, The peptidoglycan hydrolase TcpG is required for efficient conjugative transfer of pCW3 in Clostridium perfringens, Plasmid [P], vol 67, issue 2, Academic Press, USA, pp. 139-147.

Beckham, S.A., Piedrafita, D.M., Phillips, C.I., Samarawickrema, N., Law, R.H.P., Smooker, P.M., Quinsey, N.S., Irving, J.A., Greenwood, D.L., Verhelst, S.H.L., Bogyo, M., Turk, B., Coetzer, T.H., Wijeyewickrema, L.C., Spithill, T.W., Pike, R.N., 2009, A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites, International Journal of Biochemistry and Cell Biolog..., vol 41, issue 7, Pergamon, UK, pp. 1601-1612.

McAlister, A.D., Sroka, A., Fitzpatrick, R.E., Quinsey, N.S., Travis, J., Potempa, J., Pike, R.N., 2009, Gingipain enzymes from Porphyromonas gingivalis preferentially bind immobilized extracellular proteins: A mechanism favouring colonization?, Journal of Periodontal Research, vol 44, Wiley-Blackwell Munksgaard, Denmark, pp. 348-353.

Murray-Rust, T.A., Kerr, F.K., Thomas, A.R., Wu, T.J., Yongqing, T., Ong, P.C., Quinsey, N.S., Whisstock, J.C., Wagenaar-Bos, I.C., Freeman, C., Pike, R.N., 2009, Modulation of the proteolytic activity of the complement protease C1s by polyanions: Implications for polyanion-mediated acceleration of interaction between C1s and SERPING1, Biochemical Journal [P], vol 422, issue 2, Portland Press Ltd, UK, pp. 295-303.

Ng, N.M., Quinsey, N.S., Matthews, A.Y., Kaiserman, D., Wijeyewickrema, L.C., Bird, P.I., Thompson, P.E., Pike, R.N., 2009, The effects of exosite occupancy on the substrate specificity of thrombin, Archives Of Biochemistry And Biophysics [P], vol 489, issue 1-2, Academic Press, USA, pp. 48-54.

Gordon, S.L., Quinsey, N.S., Dunkley, P.R., Dickson, P.W., 2008, Tyrosine hydroxylase activity is regulated by two distinct dopamine-binding sites, Journal of Neurochemistry, vol 106, issue 4, Wiley-Blackwell Publishing Ltd., United Kingdom, United States, pp. 1614-1623.

Bromfield, K.M., Quinsey, N.S., Duggan, P.J., Pike, R.N., 2006, Approaches to selective peptidic inhibitors of factor Xa, Chemical Biology & Drug Design, vol 68, issue 1, Blackwell Publishing, Oxford England, pp. 11-19.

Beckham, S.A., Law, R.H., Smooker, P.M., Quinsey, N.S., Caffrey, C.R., McKerrow, J.H., Pike, R.N., Spithill, T.W., 2006, Production and processing of a recombinant Fasciola hepatica cathepsin B-like enzyme (FhcatB1) reveals potential processing mechanisms in the parasite, Biological Chemistry, vol 387, issue 8, Walter de Gruyter & Co., Berlin Germany, pp. 1053-1061.

Kerr, F.K., O'Brien, G., Quinsey, N.S., Whisstock, J., Boyd, S.E., Garcia De La Banda, M.J., Kaiserman, D., Matthews, A.Y., Bird, P.I., Pike, R.N., 2005, Elucidation of the substrate specificity of the C1s protease of the classical complement pathway, Journal of Biological Chemistry, vol 280, issue 47, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 39510-39514.

Quinsey, N.S., Pike, R.N., 2005, Substrate specificity of mannose lectin binding associated serine proteinase 3, Febs Journal, vol 272, Blackwell Publishing, Oxford England, p. 174.

Horvath, A.J., Irving, J.A., Rossjohn, J., Law, R.H.P., Bottomley, S.P., Quinsey, N.S., Pike, R.N., Coughlin, P.B., Whisstock, J., 2005, The murine orthologue of human antichymotrypsin: a structural paradigm for CLADE A3 serpins, Journal of Biological Chemistry, vol 280, issue 52, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 43168-43178.

Quinsey, N.S., Greedy, A.L., Bottomley, S.P., Whisstock, J.C., Pike, R.N., 2004, Antithrombin: in control of coagulation, The International Journal of Biochemistry & Cell Biology, vol 36, issue 3, Pergamon-Elsevier Science Ltd, Kidlington England, pp. 386-389.

O'Brien, G., Quinsey, N.S., Whisstock, J.C., Pike, R.N., 2003, Importance of the prime subsites of the C1s protease of the classical complement pathway for recognition of substrates, Biochemistry, vol 42, issue 50, American Chemical Society, Washington USA, pp. 14939-14945.

Quinsey, N.S., Fitton, H.L., Coughlin, P.B., Whisstock, J.C., Dafforn, T.R., Carrell, R.W., Bottomley, S.P., Pike, R.N., 2003, Introduction of a mutation in the shutter region of antithrombin (Phe77 Leu) increases affinity for heparin and decreases thermal stability, Biochemistry, vol 42, issue 34, American Chemical Society, Washington USA, pp. 10169-10173.

Quinsey, N.S., Whisstock, J.C., Le Bonniec, B., Louvain, V., Bottomley, S.P., Pike, R.N., 2002, Molecular determinants of the mechanisms underlying acceleration of the interaction between antithrombin and factor Xa by heparin pentasaccharide, The Journal of Biological Chemistry, vol 277, issue 18, American Society of Biochemistry and Molecular Biology, Bethesda MS USA, pp. 15971-15978.