Dr Jacqueline Donoghue - Researcher Profile

Biography

Jacqueline works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: Monash University

Year awarded: 2009

REPRODUCTIVE SCIENCE

Institution: Monash University

Year awarded: 1997

APPLIED SCIENCE

Institution: RMIT

Year awarded: 1992

Publications

Journal Articles

Koziolek, E.J., Donoghue, J.F., Bentley, J.D., Lovrecz, G.O., Dolezal, O., Ward, C.W., Rothacker, J., Nice, E., Burgess, A.W., Hafner, M., Johns, T.G., Adams, T.E., 2012, A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation, Growth Factors [P], vol 30, issue 5, Informa Healthcare, United Kingdom, pp. 310-319.

Donoghue, J., McGavigan, C., Lederman, F., Cann, L., Fu, L., Dimitriadis, E., Girling, J., Rogers, P., 2012, Dilated thin-walled blood and lymphatic vessels in human endometrium: a potential role for VEGF-D in progestin-induced break-through bleeding, PLoS ONE [P], vol 7, issue 2 (Art No: e30916), Public Library of Science, United States, pp. 1-10.

Greenall, S., Gherardi, E., Liu, Z., Donoghue, J.F., Vitali, A.A., Li, Q., Murphy, R., Iamele, L., Scott, A.M., Johns, T.G., 2012, Non-agonistic bivalent antibodies that promote c-MET degradation and inhibit tumor growth and others specific for tumor related c-MET, PLoS ONE [P], vol 7, issue 4 (Art. No: e34658), Public Library of Science, United States, pp. 1-10.

Donoghue, J., Bogler, O., Johns, T., 2011, A simple guide screw method for intracranial xenograft studies in mice, Journal of Visualized Experiments [E], vol 55, issue e3157, Journal of Visualized Experiments, United States, pp. 1-5.

Ymer, S., Greenall, S., Cvrljevic, A., Cao, D., Donoghue, J., Epa, V., Scott, A., Adams, T., Johns, T., 2011, Glioma specific extracellular missense mutations in the first cysteine rich region of Epidermal Growth Factor Receptor (EGFR) initiate ligand independent activation, Cancers [E], vol 3, issue 2, M D P I AG, Switzerland, pp. 2032-2049.

Girling, J.E., Donoghue, J.F., Lederman, F.L., Cann, L.M., Achen, M.G., Stacker, S.A., Rogers, P.A.W., 2010, Vascular endothelial growth factor-D over-expressing tumor cells induce differential effects on uterine vasculature in a mouse model of endometrial cancer, Reproductive Biology and Endocrinology [P], vol 8, issue Art. No. 84, BioMed Central Ltd, UK, pp. 1-14.

Rogers, P.A.W., Donoghue, J.F., Walter, L.M., Girling, J.E., 2009, Endometrial angiogenesis, vascular maturation, and lymphangiogenesis, Reproductive Sciences, vol 16, Sage Publications, Thousand Oaks, CA. USA, pp. 147-151.

Pillay, V., Allaf, L., Wilding, A., Donoghue, J.F., Court, N.W., Greenall, S.A., Scott, A.M., Johns, T.G., 2009, The plasticity of oncogene addiction: Implications for targeted therapies directed to receptor tyrosine kinases, Neoplasia [P], vol 11, issue 5, Neoplasia Press, United States, pp. 448-458.

Rogers, P.A.W., Donoghue, J.F., Girling, J.E., 2008, Endometrial lymphangiogensis, Placenta, vol 29, W B Saunders Co, London, UK, pp. 48-54.

Donoghue, J.F., Lederman, F.L., Susil, B., Rogers, P.A.W., 2007, Lymphangiogensis of normal endometrium and endometrial adenocarcinoma, Human Reproduction, vol 22, issue 6, Oxford University Press, UK & Belgium, pp. 1705-1713.

Rombauts, L., Donoghue, J.F., Cann, L.M., Jones, R.L., Healy, D.L., 2006, Activin-A secretion is increased in the eutopic endometrium from women with endometriosis, Australian and New Zealand Journal of Obstetrics and Gynaecology, vol 46, Blackwell Publishing, Oxford UK, pp. 148-153.

Conference Proceedings

Rogers, P.A.W., Donoghue, J.F., Cann, L.M., Girling, J.E., 2006, Increased blood and lymph vessel diameter in progestin exposed human endometrium is associated with elevated levels of VEGF-D, Journal of The Society for Gynecologic Investigation, 22-25 March, Elsevier Science Inc, New York NY USA, pp. 82A-83A.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

ErbB4: Prognostic significance and theapeutic target in brain cancers.

Supervisors:

Johns, T (Main), Donoghue, J (Associate).