Assoc Prof Sharon Ricardo - Researcher Profile

Biography

Sharon works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as an Associate Professor.

Qualifications

PHD - MEDICINE, DENTISTRY & HEALTH SCIENCES

Institution: University of Melbourne, Melbourne

Year awarded: 1994

BACHELOR OF SCIENCE(HONS)

Institution: University of Melbourne

Year awarded: 1989

Publications

Book Chapters

Cochrane, A.L., Ricardo, S.D., 2003, Oxidant stress and regulation of chemokines in the development of renal interstitial fibrosis, in Renal Fibrosis, eds Mohammed S Razzaque and Takashi Taguchi, Karger, Basel Switzerland, pp. 102-119.

Journal Articles

Ding, A., Kalaignanasundaram, P., Ricardo, S.D., Abdelkader, A., Witting, P.K., Broughton, B.R., Kim, H.B., Wyse, B.F., Phillips, J.K., Evans, R.G., 2012, Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease, Clinical and Experimental Pharmacology and Physiology [E], vol 39, issue 11, Wiley-Blackwell Publishing Asia, Australia, pp. 917-929.

Deane, J., Ricardo, S., 2012, Emerging roles for renal primary cilia in epithelial repair, International Review of Cell and Molecular Biology [P], vol 293, Academic Press, United States, pp. 169-193.

Wise, A., Ricardo, S., 2012, Mesenchymal stem cells in kidney Inflammation and repair, Nephrology [E], vol 17, issue 1, Wiley-Blackwell Publishing Asia, Australia, pp. 1-10.

Song, B., Sun, G., Herszfeld, D., Sylvain, A., Campanale, N.V., Hirst, C.E., Caine, S., Parkington, H.C., Tonta, M.A., Coleman, H.A., Short, M.A., Ricardo, S.D., Reubinoff, B., Bernard, C.C.A., 2012, Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis, Stem Cell Research [P], vol 8, issue 2, Elsevier BV, The Netherlands, pp. 259-273.

Chan, C., Moore, J., Budzyn, K., Guida, E., Diep, H., Vinh, A., Jones, E.S., Widdop, R.E., Armitage, J.A., Sakkal, S., Ricardo, S.D., Sobey, C.G., Drummond, G.R., 2012, Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice, Hypertension [P], vol 60, issue 5, Lippincott Williams & Wilkins, USA, pp. 1207-1212.

Song, B., Smink, A., Jones, C., Callaghan, J.M., Firth, S.D., Bernard, C.C., Laslett, A.L., Kerr, P.G., Ricardo, S.D., 2012, The directed differentiation of human iPS cells into kidney podocytes, PLoS ONE [P], vol 7, issue 9 (Art. No.: e46453), Public Library of Science, USA, pp. 1-9.

Verghese, E., Johnson, C.J., Bertram, J.F., Ricardo, S.D., Deane, J.A., 2012, The fate of bone marrow-derived cells carrying a polycystic kidney disease mutation in the genetically normal kidney, BMC Nephrology [P], vol 13, issue 1 (Art. No.: 91), BioMed Central Ltd, United Kingdom, pp. 1-11.

Kerr, J.B., Brogan, L., Myers, M., Hutt, K.J., Mladenovska, T., Ricardo, S.D., Hamza, K., Scott, C.L., Strasser, A., Findlay, J.K., 2012, The primordial follicle reserve is not renewed after chemical or gamma-irradiation mediated depletion, Reproduction [P], vol 143, issue 4, BioScientifica Ltd, UK, pp. 469-476.

Alikhan, M., Jones, C., Williams, T., Beckhouse, A., Fletcher, A., Kett, M., Sakkal, S., Samuel, C.S., Ramsay, R., Deane, J., Wells, C., Little, M., Hume, D., Ricardo, S., 2011, Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses, American Journal Of Pathology [P], vol 179, issue 3, Elsevier Inc., USA, pp. 1243-1256.

Song, B., Niclis, J., Alikhan, M., Sakkal, S., Sylvain, A., Kerr, P., Laslett, A., Bernard, C., Ricardo, S., 2011, Generation of induced pluripotent stem cells from human kidney mesangial cells, Journal Of The American Society Of Nephrology [P], vol 22, issue 7, American Society of Nephrology, USA, pp. 1213-1220.

Verghese, E., Zhuang, J., Saiti, D., Ricardo, S.D., Deane, J.A., 2011, In vitro investigation of renal epithelial injury suggests that primary cilium length is regulated by hypoxia-inducible mechanisms, Cell Biology International [P], vol 35, issue 9, Portland Press Ltd, UK, pp. 909-913.

Li, J., Qu, X., Yao, J., Caruana, G., Ricardo, S.D., Yamamoto, Y., Yamamoto, H., Bertram, J.F., 2010, Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy, Diabetes [P], vol 59, issue 10, American Diabetes Association, USA, pp. 2612-2624.

Williams, T.M., Little, M.H., Ricardo, S.D., 2010, Macrophages in renal development, injury, and repair, Seminars in Nephrology [P], vol 30, issue 3, WB Saunders Co., USA, pp. 255-267.

Li, J., Qu, X., Ricardo, S.D., Bertram, J.F., Nikolic-Paterson, D.J., 2010, Resveratrol inhibits renal fibrosis in the obstructed kidney: Potential role in deacetylation of Smad3, American Journal Of Pathology [P], vol 177, issue 3, American Society for Investigative Pathology, USA, pp. 1065-1071.

Zhuang, J., Deane, J.A., Yang, R., Li, J., Ricardo, S.D., 2010, SCUBE1, a novel developmental gene involved in renal regeneration and repair, Nephrology Dialysis Transplantation [P], vol 25, Oxford University Press, UK, pp. 1421-1428.

Lin, S.A., Kolle, G., Grimmond, S.M., Zhou, Q., Doust, E., Little, M.H., Aronow, B., Ricardo, S.D., Pera, M.F., Bertram, J.F., Laslett, A.L., 2010, Subfractionation of differentiating human embryonic stem cell populations allows the isolation of a mesodermal population enriched for intermediate mesoderm and putative renal progenitors, Stem Cells and Development [P], vol 19, issue 10, Mary Ann Liebert, Inc. Publishers, USA, pp. 1637-1648.

Verghese, E., Ricardo, S.D., Weidenfeld, R., Zhuang, J., Hill, P.A., Langham, R.G., Deane, J.A., 2009, Renal primary cilia lengthen after acute tubular necrosis, Journal Of The American Society Of Nephrology [P], vol 20, issue 10, American Society of Nephrology, USA, pp. 2147-2153.

Wang, L., Weidenfeld, R., Verghese, E., Ricardo, S.D., Deane, J.A., 2008, Alterations in renal cilium length during transient complete ureteral obstruction in the mouse, Journal of Anatomy, vol 213, issue 2, Wiley-Blackwell Publishing Ltd., United Kingdom, pp. 79-85.

Ricardo, S.D., Van Goor, H., Eddy, A.A., 2008, Macrophage diversity in renal injury and repair, Journal of Clinical Investigation, vol 118, issue 11, American Society for Clinical Investigation, United States, pp. 3522-3530.

Verghese, E., Weidenfeld, R., Bertram, J.F., Ricardo, S.D., Deane, J.A., 2008, Renal Cilia display length alterations following tubular injury and are present early in epithelial repair, Nephrology Dialysis Transplantation, vol 23, Oxford University Press, Oxford England UK, pp. 834-841.

Rae, F., Woods, K., Sasmono, T., Campanale, N.V., Taylor, D., Ovchinnikov, D.A., Grimmond, S.M., Hume, D.A., Ricardo, S.D., Little, M.H., 2007, Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter, Developmental Biology, vol 308, issue 1, Academic Press Inc Elsevier Science, San Diego CA USA, pp. 232-246.

Deane, J.A., Ricardo, S.D., 2007, Polycystic kidney disease and the renal cilium (Review Article), Nephrology (Carlton), vol 12, issue 6, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. 559-564.

Li, J., Deane, J.A., Campanale, N.V., Bertram, J.F., Ricardo, S.D., 2007, The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis, Stem Cells, vol 25, issue 3, Alphamed Press, Durham USA, pp. 697-706.

Li, J., Deane, J.A., Campanale, N.V., Bertram, J.F., Ricardo, S.D., 2006, Blockade of p38 mitogen-activated protein kinase and TGF-beta1/Smad signaling pathways rescues bone marrow-derived peritubular capillary endothelial cells in adriamycin-induced nephrosis, Journal of the American Society of Nephrology, vol 17, issue 10, American Society Nephrology, Washington USA, pp. 2799-2811.

Li, J., Campanale, N.V., Liang, R., Deane, J.A., Bertram, J.F., Ricardo, S.D., 2006, Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy, The American Journal of Pathology, vol 169, issue 5, American Society for Investigative Pathology, Bethesda USA, pp. 1527-1540.

Challen, G., Bertoncello, I., Deane, J., Ricardo, S., Little, M., 2006, Kidney side population reveals multilineage potential and renal functional capacity but also cellular heterogeneity, Journal Of The American Society Of Nephrology [P], vol 17, issue 7, American Society of Nephrology, USA, pp. 1896-1912.

Gillard, A., Scarff, K.L., Loveland, K.A.L., Ricardo, S.D., Bird, P.I., 2006, Modulation and redistribution of proteinase inhibitor 8 (Serpinb8) during kidney regeneration, American Journal of Nephrology, vol 26, issue 1, Karger, Basel Switzerland, pp. 34-42.

Guo, M., Ricardo, S.D., Deane, J.A., Shi, M., Cullen-McEwen, L.A., Bertram, J.F., 2005, A stereological study of the renal glomerular vasculature in the db/db mouse model of diabetic nephropathy, Journal of Anatomy, vol 207, issue 6, Blackwell Publishing, Oxford England, pp. 813-821.

Ricardo, S.D., Deane, J.A., 2005, Adult stem cells in renal injury and repair, Nephrology, vol 10, issue 3, Blackwell Publishing Asia, Cartlon Vic Australia, pp. 276-282.

Kramer, A., Ricardo, S.D., Kelly, D.J., Waanders, F., Van Goor, H., Gerjan, N., 2005, Modulation of osteopontin in proteinuria-induced renal interstitial fibrosis, Journal of Pathology, vol 207, John Wiley & sons Ltd., Chichester England, pp. 483-492.

Mittaz, L., Ricardo, S.D., Martinez, G., Kola, I., Kelly, D.J., Little, M.H., Hertzog, P.J., Pritchard, M.A., 2005, Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis, Nephrology Dialysis Transplantation, vol 20, Oxford University Press, Oxford England, pp. 419-423.

Cochrane, A.L., Kett, M.M., Samuel, C.S., Campanale, N.V., Anderson, W.P., Hume, D.A., Little, M.H., Bertram, J.F., Ricardo, S.D., 2005, Renal structural and functional repair in a mouse model of reversal of ureteral obstruction, Journal of the American Society of Nephrology, vol 16, Lippincott Williams & Wilkins, Philadelphia USA, pp. 3623-3630.

Lapinskas, E.J., Palmer, J., Ricardo, S.D., Hertzog, P.J., Hammacher, A., Pritchard, M.A., 2004, A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands, Histochemistry Cell Biology, vol 122, issue 6, Springer-Verlag, USA, pp. 521-526.

Wintour, E.M., Moritz, K.M., Johnson, K., Ricardo, S.D., Samuel, C.S., Dodic, M., 2003, Reduced nephron number in adult sheep, hypertensive as a result of prenatal glucocorticoid treatment, Journal of Physiology-London, vol 549, issue 3, Cambridge University Press, New York USA, pp. 929-935.

Kelly, D.J., Wilkinson-Berka, J.L., Ricardo, S.D., Cox, A.J., Gilbert, R., 2002, Progression of tubulointerstitial injury by osteopontin-induced macrophage recruitment in advanced diabetic nephropathy of transgenic (mRen-2) 27 rats, Nephrology Dialysis Transplantation, vol 17, Oxford University Press, Oxford UK, pp. 985-991.

Ricardo, S.D., Cochrane, A., 2002, The Development of Oxidant Stress in Renal Interstitial Fibrosis: Role of Angiotensin II, Free Radical Biology & Medicine, vol 33, issue 1, Elsevier Science, London UK, pp. 281-288.

Cowley, B.D., Ricardo, S.D., Nagao, S., Diamond, J.R., 2001, Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats, Kidney International, vol 60, issue 6, Blackwell Science Inc., Malden USA, pp. 2087-2096.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The Therapeutic Use of Mesenchymal Stem Cells for Treating Kidney Disease..

Supervisors:

Ricardo, S (Main).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The combined effects of mesenchymal stem cells & anti-fibrotics in a model of kidney disease.

Supervisors:

Ricardo, S (Main), Samuel, C (Associate).

Completed Supervision

Student:

Alikhan, M.

Program of Study:

Regenerative potential of colony-stimulating factor-1 therapy and macrophages in renal disease. (PHD) 2012.

Supervisors:

Ricardo, S (Main), Deane, J (Associate).

Student:

Cochrane, A.

Program of Study:

Novel approaches for understanding renal injury, repair and regeneration. (PHD) 2009.

Supervisors:

Ricardo, S (Main), Bertram, J (Associate).

Student:

D'Arcy, A.

Program of Study:

. 2008.

Supervisors:

Ricardo, S (Main).

Student:

Hepper, C.

Program of Study:

Modulations of Cellular Antioxidant Enzymes and PKC-beta in the Development of Experimental Diabetic Nephropathy.. (Masters) 2003.

Supervisors:

Bertram, J (Main), Ricardo, S (Associate).

Student:

Jones, C.

Program of Study:

The development of colony-stimulating factor-1 as a therapy to promote organ maturation. (PHD) 2012.

Supervisors:

Ricardo, S (Main), Laslett, A (Associate).

Student:

Lee, G.

Program of Study:

KIDNEY DEVELOPMENT. 2005.

Supervisors:

Ricardo, S (Main), Bertram, J (Associate).

Student:

Li, J.

Program of Study:

The role of bone marrow-derived cells in the progression of renal disease. (PHD) 2006.

Supervisors:

Ricardo, S (Main), Bertram, J (Associate).

Student:

Tan, C.

Program of Study:

Epithelial progenitor cells in the human endometrium and endometriosis. (PHD) 2011.

Supervisors:

Gargett, C (Main), Ricardo, S (Associate).

Student:

Verghese, E.

Program of Study:

Using polycystic kidney disease to understand cilium mediated endogenous repair and bone marrow mediated exogenous repair. (PHD) 2010.

Supervisors:

Deane, J (Joint), Ricardo, S (Joint-Co).

Student:

Zhuang, J.

Program of Study:

SCUBE1, A NOVEL DEVELOPMENTAL GENE IMPLICATED IN RENAL REGENERATION AND REPAIR. (Masters) 2008.

Supervisors:

Ricardo, S (Main).