Prof Fabienne Mackay-Fisson - Researcher Profile

Biography

Fabienne works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Professor.

http://www.med.monash.edu.au/immunology/research/b-lymphocytes-baff-autoimm-lab.html

Qualifications

PHD IMMUNOLOGY- MOLECULAR BIOLOGY

Institution: Louis Pasteur University

Year awarded: 1994

DIPLOMA PF ENGINEERING (BIOLOGICAL ENGINEERING)

Institution: University Blaise Pascal Clermont-Ferrand

Year awarded: 1989

DEA (HONOURS IN CELLULAR AND MOLECULAR BIOLOGY)

Institution: University Claise Pascal Clermont-Ferrard

Year awarded: 1989

Publications

Journal Articles

Vincent, F., Morand, E.F., Murphy, K., Mackay-Fisson, F., Mariette, X., Marcelli, C., 2012, Antidrug antibodies (ADAb) to tumour necrosis factor (TNF)-specific neutralising agents in chronic inflammatory diseases: A real issue, a clinical perspective, Annals Of The Rheumatic Diseases [P], vol 72, issue 2, B M J Group, United Kingdom, pp. 165-178.

Bergmann, H., Yabas, M., Short, A., Miosge, L., Barthel, N., Teh, C., Roots, C.M., Bull, K., Jeelall, Y., Horikawa, K., Whittle, B., Balakishnan, B., Sjollema, G., Bertram, E.M., Mackay-Fisson, F., Rimmer, A., Cornall, R., Field, M., Andrews, D., Goodnow, C., Enders, A., 2012, B-cell survival, surface BCR and BAFF-R expression, CD74 metabolism and CD8 DC's require the intramembrane endopeptidase SPPL2A, Journal of Experimental Medicine [P], vol 210, issue 1, Rockefeller University Press, United States, pp. 31-40.

Vincent, F., Morand, E., Mackay-Fisson, F., 2012, BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus, Immunology And Cell Biology [P], vol 90, issue 3, Nature Publishing Group, United Kingdom, pp. 293-303.

Fairfax, K., Mackay, I.R., Mackay-Fisson, F., 2012, BAFF/BLyS inhibitors: a new prospect for treatment of systemic lupus erythematosus, Iubmb Life [P], vol 64, issue 7, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. 595-602.

Haege, S., Einer, C., Thiele, S., Mueller, W., Nietzsche, S., Lupp, A., Mackay-Fisson, F., Schulz, S., Strumm, R., 2012, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney, PLoS ONE [P], vol 7, issue 8, Public Library of Science, United States, pp. 1-10.

Kyaw, T.S., Tay, C., Hosseini, H., Kanellakis, P., Gadowski, T., Mackay-Fisson, F., Tipping, P.G., Bobik, A., Toh, B., 2012, Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE-/- mice attenuates atherosclerosis by potently ameliorating arterial inflammation, PLoS ONE [P], vol 7, issue 1, Public Library of Science, United States, p. e29371.

Vincent, F., Bourke, P., Morand, E.F., Mackay-Fisson, F., Bossingham, D., 2012, Focus on systemic lupus erythematosus in indigenous Australians: toward a better understanding of autoimmune diseases., Internal Medicine Journal [P], Wiley-Blackwell Publishing Asia, Australia.

Liu, X.Q., Stacey, K.J., Horne-Debets, J.M., Cridland, J.A., Fischer, K., Narum, D., Mackay-Fisson, F., Pierce, S.K., Wykes, M.N., 2012, Malaria infection alters the expression of B-cell activating factor resulting in diminished memory antibody responses and survival., European Journal Of Immunology [P], vol 42, issue 12, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 3291-3301.

Macia, L., Yulyaningsih, E., Pangon, L., Nguyen, A., Lin, S., Shi, Y., Zhang, L., Bijker, M., Grey, S., Mackay-Fisson, F., Herzog, H., Salis-Sainsbury, A., 2012, Neuropeptide Y1 Receptor in Immune Cells Regulates Inflammation and Insulin Resistance Associated With Diet-Induced Obesity., Diabetes [P], vol 61, issue 12, American Diabetes Association, United States, pp. 3228-3238.

Gantier, M., McCoy, C., Rusinova, I., Saulep, D., Wang, D., Xu, D., Irving, A., Behlke, M., Hertzog, P., Mackay-Fisson, F., Williams, B., 2011, Analysis of microRNA turnover in mammalian cells following Dicer1 ablation, Nucleic Acids Research [P], vol 39, issue 13, Oxford University Press, United Kingdom, pp. 5692-5703.

Sanchez-Alcaniz, J., Haege, S., Mueller, W., Pla, R., Mackay-Fisson, F., Schulz, S., Lopez-Bendito, G., Stumm, R., Marin, O., 2011, Cxcr7 controls neuronal migration by regulating chemokine responsiveness, Neuron [P], vol 69, issue 1, Cell Press, United States, pp. 77-90.

Fletcher, C., Groom, J., Woehl, B., Leung, H., Mackay, C., Mackay-Fisson, F., 2011, Development of autoimmune nephritis in genetically asplenic and splenectomized BAFF transgenic mice, Journal Of Autoimmunity [P], vol 36, issue 2, Academic Press, United Kingdom, pp. 125-134.

Tardivel, A., Schneider, P., Mackay-Fisson, F., Strasser, A., 2011, Jurg Tschopp 1951-2011 OBITUARY, Nature Immunology [P], vol 12, issue 5, NATURE PUBLISHING GROUP, 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA, USA, p. 367.

Bossen, C., Tardivel, A., Willen, L., Fletcher, C., Perroud, M., Beermann, F., Rolink, A., Scot, M., Mackay-Fisson, F., Schneider, P., 2011, Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses, European Journal Of Immunology [P], vol 41, issue 3, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 787-797.

Macia, L., Rao, p., Wheway, J., Sierro, F., Mackay-Fisson, F., Herzog, H., 2011, Y1 signalling has a critical role in allergic airway inflammation, Immunology And Cell Biology [P], vol 89, issue 8, Nature Publishing Group, UK, pp. 882-888.

Mackay-Fisson, F., Figgett, W., Saulep, D., Le Page, M., Hibbs, M., 2010, B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor, Immunological Reviews [P], vol 237, issue 1, Wiley-Blackwell Publishing, Inc., United States, pp. 205-225.

Goodnow, C.C., Vinuesa, C.G., Randall, K.L., Mackay, F., Brink, R., 2010, Control systems and decision making for antibody production, Nature Immunology [P], vol 11, issue 8, Nature Publishing Group, United States, pp. 681-688.

Marino Moreno, E., Villanueva, J., Walters, S., Liuwantara, D., Mackay-Fisson, F., Grey, S., 2009, CD4+CD25+ T-cells control autoimmunity in the absence of B-cells, Diabetes [P], vol 58, issue 7, American Diabetes Association, United States, pp. 1568-1577.

Mackay, F., Schneider, P., 2009, Cracking the BAFF code, Nature Reviews Immunology [P], vol 9, issue 7, Nature Publishing Group, United Kingdom, pp. 491-502.

Randall, K.L., Lambe, T., Johnson, A., Treanor, B., Kucharska, E., Domaschenz, H., Whittle, B., Tze, L.E., Enders, A.C., Crockford, T., Bouriez-Jones, T., Alston, D., Cyster, J.G., Lenardo, M.J., Mackay-Fisson, F., Deenick, E.K., Tangye, S.G., Chan, T.D., Camidge, T., Brink, R., Vinuesa, C.G., Batista, F.D., Cornall, R.J., Goodnow, C., 2009, Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production, Nature Immunology [P], vol 10, issue 12, Nature Publishing Group, United States, pp. 1283-1291.

Walters, S., Webster, K.E., Sutherland, A.P., Gardam, S., Groom, J., Liuwantara, D., Marino Moreno, E., Thaxton, J., Weinberg, A., Mackay-Fisson, F., Brink, R., Sprent, J., Grey, S., 2009, Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses, Journal Of Immunology [P], vol 182, issue 2, American Association of Immunologists, United States, pp. 793-801.

Maslowski, K.M., Vieira, A.T., Ng, A., Kranich, J., Sierro, F., Yu, D., Schilter, H.C., Rolph, M.S., Mackay-Fisson, F., Artis, D., Xavier, R.J., Teixeira, M.M., Mackay, C.R., 2009, Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43, Nature [P], vol 461, issue 7268, Nature Publishing Group, UK, pp. 1282-1286.

Groom, J.R., Mackay-Fisson, F., 2008, B cells flying solo, Immunology And Cell Biology [P], vol 86, issue 1, Nature Publishing Group, United Kingdom, pp. 40-46.

Marino, E., Batten, M., Groom, J.R., Walters, S., Liuwantara, D., Mackay-Fisson, F., Grey, S., 2008, Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells, Diabetes [P], vol 57, issue 2, American Diabetes Association, United States, pp. 395-404.

Sasaki, Y., Calado, D.P., Derudder, E., Zhang, B., Shimizu, Y., Mackay-Fisson, F., Nishikawa, S., Rajewsky, K., Schmidt-Supprian, M., 2008, NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells, Proceedings Of The National Academy Of Sciences O..., vol 105, issue 31, National Academy of Sciences, United States, pp. 10883-10888.

Mackay-Fisson, F., Schneider, P., 2008, TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties, Cytokine and Growth Factor Reviews [P], vol 19, issue 3-4, Elsevier Ltd, United Kingdom, pp. 263-276.

Bossen, C., Cachero, T.G., Tardivel, A., Ingold, K., Willen, L., Dobles, M., Scott, M., Maquelin, A., Belnoue, E., Siegrist, C., Chevrier, S., Acha-Orbea, H., Leung, H., Mackay-Fisson, F., Tschopp, J., Schneider, P., 2008, TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts, Blood [P], vol 111, issue 3, American Society of Hematology, United States, pp. 1004-1012.

Gardam, S., Sierro, F., Basten, A., Mackay-Fisson, F., Brink, R., 2008, TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor, Immunity [P], vol 28, issue 3, Cell Press, United States, pp. 391-401.

Mackay-Fisson, F., Groom, J.R., Tangye, S.G., 2007, An important role for B-cell activation factor and B cells in the pathogenesis of Sjogren's syndrome, Current Opinion In Rheumatology [P], vol 19, issue 5, Lippincott Williams & Wilkins, United States, pp. 406-413.

Mackay-Fisson, F., Silveira, P.A., Brink, R., 2007, B cells and the BAFF/APRIL axis: Fast-forward on autoimmunity and signaling, Current Opinion in Immunology [P], vol 19, issue 3, Elsevier Ltd., Current Opinion Journals, United Kingdom, pp. 327-336.

Groom, J.R., Fletcher, C.A., Walters, S.N., Gray, S.T., Watt, S.V., Sweet, M.J., Smyth, M.J., Mackay, C.R., Mackay-Fisson, F., 2007, BAFF and MyD88 signals promote a lupuslike disease independent of T cells, Journal of Experimental Medicine [P], vol 204, issue 8, Rockefeller University Press, USA, pp. 1959-1971.

Sierro, F., Biben, C., Martinez-Munoz, L., Mellado, M., Ransohoff, R.M., Li, M., Woehl, B., Leung, H., Groom, J., Batten, M., Harvey, R.P., Matinez-A, C., Mackay, C.R., Mackay-Fisson, F., 2007, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7, Proceedings Of The National Academy Of Sciences O..., vol 104, issue 37, National Academy of Sciences, USA, pp. 14759-14764.

Wheway, J., Herzog, H., Mackay-Fisson, F., 2007, NPY and receptors in immune and inflammatory diseases, Current Topics in Medicinal Chemistry [P], vol 7, issue 17, Bentham Science Publishers Ltd, Netherlands, pp. 1743-1752.

Viardot, A., Grey, S., Mackay-Fisson, F., Chisholm, D., 2007, Potential antiinflammatory role of insulin via the preferential polarization of effector T cells toward a T helper 2 phenotype, Endocrinology [P], vol 148, issue 1, The Endocrine Society, United States, pp. 346-353.

Wheway, J., Herzog, H., Mackay-Fisson, F., 2007, The Y1 receptor for NPY: A key modulator of the adaptive immune system, Peptides [P], vol 28, issue 2, Elsevier Inc., United States, pp. 453-458.

Ng, L., Ng, C., Woehl, B., Sutherland, A.P., Huo, J., Xu, S., Mackay-Fisson, F., Lam, K., 2006, BAFF costimulation of Toll-like receptor-activated B-1 cells, European Journal Of Immunology [P], vol 36, issue 7, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 1837-1846.

Fletcher, C.A., Sutherland, A.P., Groom, J.R., Batten, M., Ng, L., Gommerman, J., Mackay-Fisson, F., 2006, Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone cells, European Journal Of Immunology [P], vol 36, issue 9, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 2504-2514.

Lee, H., Zahra, D., Vogelzang, A., Newton, R., Thatcher, J., Quan, A., So, T., Zwirner, J., Koentgen, F., Padkjaer, S.B., Mackay-Fisson, F., Whitfeld, P.L., Mackay, C.R., 2006, Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies, Nature Biotechnology [P], vol 24, issue 10, Nature Publishing Group, USA, pp. 1279-1284.

Jeffrey, K.L., Brummer, T., Rolph, M.S., Liu, S.M., Callejas, N.A., Grumont, R.J., Gillieron, C., Mackay-Fisson, F., Grey, S., Camps, M., Rommel, C., Gerondakis, S.D., Mackay, C.R., 2006, Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1, Nature Immunology [P], vol 7, issue 3, Nature Publishing Group, USA, pp. 274-283.

Sutherland, A.P., Mackay-Fisson, F., Mackay, C.R., 2006, Targeting BAFF: Immunomodulation for autoimmune diseases and lymphomas, Pharmacology and Therapeutics [P], vol 112, issue 3, Elsevier Inc., United States, pp. 774-786.

Lukashev, M., LePage, D., Wilson, C., Bailly, V., Garber, E., Lukashin, A., Ngam-ek, A., Zeng, W., Allaire, N., Perrin, S., Xu, X., Szeliga, K., Wortham, K., Kelly, R., Bottiglio, C., Ding, J., Griffith, L., Heaney, G., Silverio, E., Yang, W., Jarpe, M., Fawell, S., Reff, M., Carmillo, A., Miatkowski, K., Amatucci, J., Crowell, T., Prentice, H., Meier, W., Violette, S.M., Mackay-Fisson, F., Yang, D., Hoffman, R., Browning, J.L., 2006, Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy, Cancer Research [P], vol 66, issue 19, American Association for Cancer Research, United States, pp. 9617-9624.

Mackay-Fisson, F., Leung, H., 2006, The role of the BAFF/APRIL system on T cell function, Seminars In Immunology [P], vol 18, issue 5, Academic Press, United Kingdom, pp. 284-289.

Mackay-Fisson, F., Cancro, M.P., 2006, Travelling with the BAFF/BLyS family: Are we there yet?, Seminars In Immunology [P], vol 18, issue 5, Academic Press, United Kingdom, pp. 261-262.

Wheway, J., Mackay, C.R., Newton, R., Sainsbury, A., Boey, D., Herzog, H., Mackay-Fisson, F., 2005, A fundamental bimodal role for neuropeptide Y1 receptor in the immune system, Journal of Experimental Medicine [P], vol 202, issue 11, Rockefeller University Press, United States, pp. 1527-1538.

Sutherland, A.P., Ng, L., Fletcher, C.A., Shum, B.O., Newton, R., Grey, S., Rolph, M.S., Mackay-Fisson, F., Mackay, C.R., 2005, BAFF augments certain Th1-associated inflammatory responses, Journal Of Immunology [P], vol 174, issue 9, American Association of Immunologists, United States, pp. 5537-5544.

Stohl, W., Xu, D., Kim, K.S., Koss, M.N., Jorgensen, T.N., Deocharan, B., Metzger, T.E., Bixler, S.A., Hong, Y.S., Ambrose, C., Mackay-Fisson, F., Morel, L., Putterman, C., Kotzin, B.L., Kalled, S.L., 2005, BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus, Arthritis & Rheumatism-Arthritis Care & Research [P], vol 52, issue 7, John Wiley & Sons, Inc., United States, pp. 2080-2091.

Avery, D.T., Ellyard, J.I., Mackay-Fisson, F., Corcoran, L.M., Hodgkin, P.D., Tangye, S.G., 2005, Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage, Journal Of Immunology [P], vol 174, issue 7, American Association of Immunologists, United States, pp. 4034-4042.

Ng, L., Mackay, C.R., Mackay-Fisson, F., 2005, The BAFF/APRIL system: Life beyond B lymphocytes, Molecular Immunology [P], vol 42, issue 7, Pergamon, United Kingdom, pp. 763-772.

Ng, L., Sutherland, A.P., Newton, R., Qian, F., Cachero, T.G., Scott, M.L., Thompson, J.S., Wheway, J., Chtanova, T., Groom, J., Sutton, I.J., Xin, C., Tangye, S.G., Kalled, S.L., Mackay-Fisson, F., Mackay, C.R., 2004, B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells, Journal Of Immunology [P], vol 173, issue 2, American Association of Immunologists, United States, pp. 807-817.

Shulga-Morskaya, S., Dobles, M., Walsh, M.E., Ng, L., Mackay-Fisson, F., Rao, S.P., Kalled, S.L., Scott, M.L., 2004, B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation, Journal Of Immunology [P], vol 173, American Association of Immunologists, United States, pp. 2331-2341.

Thien, M., Phan, T., Gardam, S., Amesbury, M., Basten, A., Mackay-Fisson, F., Brink, R., 2004, Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches, Immunity [P], vol 20, issue 6, Cell Press, United States, pp. 785-798.

Mecklenbrauker, I., Kalled, S.L., Leitges, M., Mackay-Fisson, F., Tarakhovsky, A., 2004, Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling, Nature [P], vol 431, issue 7007, Nature Publishing Group, United Kingdom, pp. 456-461.

Batten, M., Fletcher, C.A., Ng, L., Groom, J.R., Wheway, J., Laabi, Y., Xin, X., Schneider, P., Tschopp, J., Mackay, C.R., Mackay-Fisson, F., 2004, TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma, Journal Of Immunology [P], vol 172, issue 2, American Association of Immunologists, United States, pp. 812-822.

Tardivel, A., Tinel, A., Lens, S., Steiner, Q., Sauberli, E., Wilson, A., Mackay-Fisson, F., Rolink, A.G., Beermann, F., Tschopp, J., Schneider, P., 2004, The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF, European Journal Of Immunology [P], vol 34, issue 2, Wiley - V C H Verlag GmbH & Co. KGaA, Germany, pp. 509-518.

Mackay-Fisson, F., Tangye, S.G., 2004, The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers, Current Opinion in Pharmacology [P], vol 4, issue 4, Elsevier Ltd, United Kingdom, pp. 347-354.

Boule, M.W., Broughton, C., Mackay-Fisson, F., Akira, S., Marshak-Rothstein, A., Rifkin, I.R., 2004, Toll-like receptor 9–dependent and –independent dendritic cell activation by chromatin–immunoglobulin G complexes, Journal of Experimental Medicine [P], vol 199, issue 12, Rockefeller University Press, United States, pp. 1631-1640.

Mackay-Fisson, F., Schneider, P., Rennert, P., Browning, J.L., 2003, BAFF AND APRIL: A tutorial on B cell survival, Annual Review Of Immunology [P], vol 21, Annual Reviews, United States, pp. 231-264.

Avery, D.T., Kalled, S.L., Ellyard, J.I., Ambrose, C., Bixler, S.A., Thien, M., Brinks, R., Mackay-Fisson, F., Hodgkin, P.D., Tangye, S.G., 2003, BAFF selectively enhances the survival of plasmablasts generated from human memory B cells, Journal of Clinical Investigation [P], vol 112, issue 2, American Society for Clinical Investigation, United States, pp. 286-297.

Mackay-Fisson, F., Ambrose, C., 2003, The TNF family members BAFF and APRIL: The growing complexity, Cytokine and Growth Factor Reviews [P], vol 14, issue 3-4, Elsevier Ltd, United Kingdom, pp. 311-324.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Aberrant T helper cells In Autoimmune Diseases.

Supervisors:

Yu, D (Main), Mackay, F (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

B cells in tolerance and autoimmunity.

Supervisors:

Alderuccio, F (Main), Mackay, F (Joint).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Identifying and targeting signaling pathways in lupus using a clinically relevant model.

Supervisors:

Hibbs, M (Main), Mackay, F (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Regulation of telomerase activity and telomere remodeling in lymphocytes.

Supervisors:

Mackay, F (Main), Liu, J (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Role of BAFF and the T-independent innate immune system in systemic lupus pathogenesis.

Supervisors:

Mackay, F (Main).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The role of BAFF in CLL.

Supervisors:

Mackay, F (Main), Ting, S (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The role of NFkB1 in immune homeostasis and autoimmunity..

Supervisors:

Gugasyan, R (Main), Grigoriadis, G (Associate), Mackay, F (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The role of the adaptive immune system in the formation and progression of retinopathy.

Supervisors:

Wilkinson-Berka, J (Main), Mackay, F (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The roles of BAFF, B , NK and NKT cells in solid tumours.

Supervisors:

Mackay, F (Main).