Dr Martina Kocan - Researcher Profile

Biography

Position

Research Fellow
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences

Keywords

GPCR, signalling-bias, BRET, drug discovery

Qualifications

MASTER OF SCIENCE

Institution: Slovak Technical University - Slovak Repub.

Year awarded: 2000

BACHELOR OF BIOCHEMISTRY & BIOTECHNLOLGY

Institution: Slovak Technical University - Slovak Repub.

Year awarded: 1998

Publications

Journal Articles

Bathgate, R., Halls, M.L., Van Der Westhuizen, E.T., Callander, G., Kocan, M., Summers, R.J., 2013, Relaxin family peptides and their receptors, Physiological Reviews [P], vol 93, issue 1, The American Physiological Society, Bethesda Maryland USA, pp. 405-480.

Podolska, A., Tham, S., Hart, R.D., Seeber, R., Kocan, M., Kocan, M., Mishra, U.K., Pfleger, K., Parish, G., Nener, B.D., 2012, Biocompatibility of semiconducting AlGaN/GaN material with living cells, Sensors and Actuators, B: Chemical [P], vol 169, issue 5, Elsevier Science SA, Lausanne, Switzerland, pp. 401-406.

Shabanpoor, F., Hossain, M.A., Ryan, P.J., Belgi, A., Layfield, S., Kocan, M., Zhang, S., Samuel, C.S., Gundlach, A.L., Bathgate, R.A., Separovic, F., Wade, J.D., 2012, Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1, Journal of Medicinal Chemistry [P], vol 55, issue 4, American Chemical Society, USA, pp. 1671-1681.

See, H.B., Seeber, R.M., Kocan, M., Eidne, K.A., Pfleger, K.D.G., 2011, Application of G protein-coupled receptor-heteromer identification technology to monitor beta-arrestin recruitment to G protein-coupled receptor heteromers, Assay and Drug Development Technologies [P], vol 9, issue 1, Mary Ann Liebert, Inc. Publishers, USA, pp. 21-30.

Dehvari, N., Hutchinson, D., Nevzorova, J., Dallner, O., Sato, M., Kocan, M., Merlin, J., Evans, B., Summers, R., Bengtsson, T., 2011, Beta(2)-adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C-terminal tail, British Journal of Pharmacology [P], vol 165, issue 5, John Wiley & Sons Ltd, UK, pp. 1442-1456.

Kocan, M., Dalrymple, M.B., Seeber, R., Feldman, B.J., Pfleger, K., 2011, Enhanced BRET technology for the monitoring of agonist-induced and agonist-independent interactions between GPCRs and beta-arrestins, Frontiers in Endocrinology [E], vol 1, issue 12, Frontiers Research Foundation, Lausanne, Switzerland, pp. 1-9.

Kocan, M., Pfleger, K., 2011, Study of GPCR-protein interactions by BRET, Methods in molecular biology (Clifton, N.J.) [P], vol 746, Humana Press Inc, New York USA, pp. 357-371.

Kocan, M., See, H.B., Sampaio, N.G., Eidne, K., Feldman, B.J., Pfleger, K., 2009, Agonist-Independent Interactions between I?-Arrestins and Mutant Vasopressin Type II Receptors Associated with Nephrogenic Syndrome of Inappropriate Antidiuresis, Molecular Endocrinology [P], vol 23, issue 4, Endocrine Soc, Chevy Chase, Maryland USA, pp. 559-571.

Kocan, M., Pfleger, K., 2009, Detection of GPCR/beta-arrestin interactions in live cells using bioluminescence resonance energy transfer technology, Methods in molecular biology (Clifton, N.J.) [P], vol 552, Humana Press Inc, New York, USA, pp. 305-317.

Kocan, M., See, H.B., Seeber, R., Eidne, K., Pfleger, K.D., 2008, Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein-coupled receptors in live cells, Journal of Biomolecular Screening [P], vol 13, issue 9, Sage Publications, Inc., USA, pp. 888-898.

Kocan, M., Schaffer, S., Ishige, T., Sorger-Herrmann, U., Wendisch, V.F., Bott, M., 2006, Two-component systems of Corynebacterium glutamicum: deletion analysis and involvement of the PhoS-PhoR system in the phosphate starvation response, Journal Of Bacteriology [P], vol 188, issue 2, American Society for Microbiology, USA, pp. 724-732.