Dr Victoria Adams - Researcher Profile

Biography

Victoria works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

PHD MICROBIOLOGY

Institution: Monash University

Year awarded: 2003

Publications

Journal Articles

Porter, C.J., Bantwal, R., Bannam, T.L., Rosado, C.J., Pearce, M.C., Adams, V.M., Lyras, D., Whisstock, J.C., Rood, J.I., 2012, The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria, Molecular Microbiology [P], vol 83, issue 2, Wiley-Blackwell Publishing Ltd, UK, pp. 275-288.

Bantwal, R., Bannam, T.L., Porter, C.J., Quinsey, N.S., Lyras, D., Adams, V.M., Rood, J.I., 2012, The peptidoglycan hydrolase TcpG is required for efficient conjugative transfer of pCW3 in Clostridium perfringens, Plasmid [P], vol 67, issue 2, Academic Press, USA, pp. 139-147.

Uzal, F.A., Saputo, J., Sayeed, S., Vidal, J.E., Fisher, D.J., Poon, R., Adams, V.M., Fernandez-Miyakawa, M.E., Rood, J.I., McClane, B., 2009, Development and application of new mouse models to study the pathogenesis of Clostridium perfringens type C Enterotoxemias, Infection And Immunity [P], vol 77, issue 12, American Society for Microbiology, USA, pp. 5291-5299.

Lyras, D., O'Connor, J.R., Howarth, P.M., Sambol, S.P., Carter, G.P., Phumoonna, T., Poon, R., Adams, V.M., Vedantam, G., Johnson, S., Gerding, D., Rood, J.I., 2009, Toxin B is essential for virulence of Clostridium difficile, Nature, vol 458, issue 7242, Nature Publishing Group, UK, pp. 1176-1179.

Lyras, D., Adams, V.M., Ballard, S.A., Teng, W.L., Howarth, P., Crellin, P., Bannam, T.L., Songer, J., Rood, J.I., 2009, tISCpe8, an IS1595-family lincomycin resistance element located on a conjugative plasmid in Clostridium perfringens, Journal Of Bacteriology [P], vol 191, issue 20, American Society for Microbiology, USA, pp. 6345-6351.

Fernandez-Miyakawa, M.E., Fisher, D.J., Poon, R., Sayeed, S., Adams, V.M., Rood, J.I., Mcclane, B.E., Uzal, F.A., 2007, Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type b isolates in the mouse intravenous injection model, Infection and Immunity, vol 75, issue 3, American Society of Microbiology, Washington DC USA, pp. 1443-1452.

Fernandez-Miyakawa, M.E., Sayeed, S., Fisher, D.J., Poon, R., Adams, V.M., Rood, J.I., McClane, B.E., Saputo, J., Uzal, F.A., 2007, Development and application of an oral challenge mouse model for studying Clostridium perfringens type D infection, Infection and Immunity, vol 75, issue 9, American Society of Microbiology, Washington DC USA, pp. 4282-4288.

Hughes, M.L., Poon, R., Adams, V.M., Sayeed, S., Saputo, J., Uzal, F.A., McClane, B.E., Rood, J.I., 2007, Epsilon-toxin plasmids of Clostridium perfringens type D are conjugative, Journal of Bacteriology, vol 189, issue 21, American Society of Microbiology, Washington DC USA, pp. 7531-7538.

O'Connor, J.R., Lyras, D., Farrow, K.A., Adams, V.M., Powell, D.R., Hinds, J., Cheung, K.J., Rood, J.I., 2006, Construction and analysis of chromosomal Clostridium difficile mutants, Molecular Microbiology, vol 61, issue 5, Blackwell Publishing, UK, pp. 1335-1351.

Fisher, D.J., Fernandez-Miyakawa, M.E., Sayeed, S., Poon, R., Adams, V.M., Rood, J.I., Uzal, F.A., McClane, B.A., 2006, Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model, Infection and Immunity, vol 74, issue 9, AMER SOC MICROBIOLOGY, WASHINGTON DC USA, pp. 5200-5210.

Adams, V.M., Lucet, I., Tynan, F.E., Chiarezza, M., Howarth, P., Kim, J., Rossjohn, J., Lyras, D., Rood, J.I., 2006, Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function, Molecular Microbiology, vol 60, issue 3, Blackwell Publishing, UK, pp. 591-601.

Sayeed, S., Fernandez-Miyakawa, M.E., Fisher, D.J., Adams, V.M., Poon, R., Rood, J.I., Uzal, F.A., McClane, B.A., 2005, Epsilon-toxin Is required for most Clostridium perfringens type D vegetative culture supernatants to cause lethality in the mouse intravenous injection model, Infection and Immunity, vol 73, issue 11, American Society for Microbiology, USA, pp. 7413-7421.

Lucet, I.S., Tynan, F.E., Adams, V.M., Rossjohn, J., Lyras, D., Rood, J.I., 2005, Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens, The Journal of Biological Chemistry, vol 280, issue 4, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 2503-2511.

Adams, V.M., Lucet, I.S., Lyras, D., Rood, J.I., 2004, DNA binding properties of TnpX indicate that different synapses are formed in the excision and integration of the Tn4451 family, Molecular Microbiology, vol 53, issue 4, Blackwell Publishing Ltd, Oxford UK, pp. 1195-1207.

Lyras, D., Adams, V.M., Lucet, I., Rood, J.I., 2004, The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements, Molecular Microbiology, vol 51, issue 6, Blackwell Publishing Ltd, Oxford UK, pp. 1787-1800.

Adams, V., Lyras, D., Farrow, K.A., Rood, J.I., 2002, The clostridial mobilisable transposons, Cellular and Molecular Life Sciences, vol 59, issue 12, Birkhauser Verlag Ag, Basel Switzerland, pp. 2033-2043.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The role of conjugative plasmids of clostridium perfringens in toxin production and virulence.

Supervisors:

Rood, J (Main), Adams, V (Associate), Cheung, K (Associate).