Dr Mark Del Borgo - Researcher Profile

Biography

Mark works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY - MED, DENTISTRY & HEALTH SCI

Institution: University of Melbourne

Year awarded: 2005

BACHELOR OF SCIENCE WITH HONOURS

Institution: University of Melbourne

Year awarded: 2001

Publications

Journal Articles

Gopalan, R.D., Del Borgo, M.P., Bergman, Y.E., Unabia, S., Mulder, R.J., Wilce, M.C., Wilce, J.A., Aguilar, M.[., Perlmutter, P., 2012, Conformational stability studies of a stapled hexa-beta(3)-peptide library, Organic & Biomolecular Chemistry [P], vol 10, issue 9, R S C Publications, UK, pp. 1802-1806.

Gunzburg, M.J., Ambaye, N.D., Del Borgo, M.P., Pero, S.C., Krag, D.N., Wilce, M.C., Wilce, J.A., 2012, Interaction of the non-phosphorylated peptide G7-18NATE with Grb7-SH2 domain requires phosphate for enhanced affinity and specificity, Journal Of Molecular Recognition [P], vol 25, issue 1, John Wiley & Sons Ltd, UK, pp. 57-67.

Jones, E.S., Del Borgo, M.P., Kirsch, J., Clayton, D.J., Bosnyak, S., Welungoda, I.K., Hausler, N., Unabia, S., Perlmutter, P., Thomas, W.G., Aguilar, M.I., Widdop, R.E., 2011, A single beta-amino acid substitution to angiotensin II confers AT2 receptor selectivity and vascular function, Hypertension [P], vol 57, issue 3, Lippincott Williams & Wilkins, USA, pp. 570-576.

Ambaye, N., Pero, S., Gunzburg, M., Yap, M., Clayton, D., Del Borgo, M., Perlmutter, P., Aguilar, M., Shukla, G., Peletskaya, E., Cookson, M., Krag, D., Wilce, M., Wilce, J., 2011, Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression, Journal of Molecular Biology [P], vol 412, issue 3, Academic Press, UK, pp. 397-411.

Gunzburg, M.J., Ambaye, N.D., Hertzog, J.T., Del Borgo, M.P., Pero, S.C., Krag, D.N., Wilce, M.C., Aguilar, M.I., Perlmutter, P., Wilce, J.A., 2010, Use of SPR to study the interaction of G7-18NATE peptide with the Grb7-SH2 domain, International Journal Of Peptide Research And Therapeutics [P], vol 16, issue 3, Springer Netherlands, The Netherlands, pp. 177-184.

Bergman, Y.E., Del Borgo, M.P., Gopalan, R.D., Jalal, S., Unabia, S., Ciampini, M., Clayton, D.J., Fletcher, J.M., Mulder, R.J., Wilce, J.A., Aguilar, M.I., Perlmutter, P., 2009, Synthesis of stapled beta3-peptides through ring-closing metathesis, Organic Letters [P], vol 11, issue 19, American Chemical Society, United States, pp. 4438-4440.

Del Borgo, M.P., Blanchfield, J.T., Toth, I., 2008, Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues, Bioorganic Medicinal & Chemistry, vol 16, issue 8, Pergamon, UK, pp. 4341-4346.

Koda, Y., Del Borgo, M.P., Wessling, S.T., Lazarus, L.H., Okada, Y., Toth, I., Blanchfield, J.T., 2008, Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides, Bioorganic & Medicinal Chemistry, vol 16, issue 11, Pergamon, UK, pp. 6286-6296.

Del Borgo, M.P., Hughes, R.A., Bathgate, R., Lin, F., Kawamura, K., Wade, J.D., 2006, Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo, Journal of Biological Chemistry, vol 281, issue 19, American Society for Biochemistry & Molecular Biology Inc, USA, pp. 13068-13074.

Del Borgo, M.P., Hughes, R.A., Wade, J.D., 2005, Conformationally constrained single-chain peptide mimics of relaxin B-chain secondary structure, Journal of Peptide Science, vol 11, issue 9, John Wiley & Sons Ltd, UK, pp. 564-571.