Dr Terry Kwok-Schuelein - Researcher Profile

Biography

Terry works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Lecturer.

Qualifications

SCIENCE

Institution: University of Melbourne

Year awarded: 1999

Publications

Journal Articles

Gorrell, R.J., Xin, Y., Guan, J., Anoushiravani Tafreshi, M., Hutton, M.L., McGuckin, M.A., Ferrero, R.L., Kwok-Scheulein, T., 2013, A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system, Cellular Microbiology [P], vol E-pub, Wiley-Blackwell Publishing Ltd, UK, pp. 1-43.

Deen, N.S., Huang, S.J., Gong, L., Kwok-Schuelein, T., Devenish, R.J., 2013, The impact of autophagic processes on the intracellular fate of Helicobacter pylori: More tricks from an enigmatic pathogen?, Autophagy [P], vol 9, issue 5, Landes Bioscience, USA, pp. 1-14.

Celik, N., Webb, C.T., Leyton, D.L., Holt, K.E., Heinz, E., Gorrell, R.J., Kwok-Scheulein, T., Naderer, T., Strugnell, R.A., Speed, T.P., Teasdale, R.D., Likic, V.A., Lithgow, T.J., 2012, A bioinformatic strategy for the detection, classification and analysis of bacterial autotransporters, PLoS ONE [P], vol 7, issue 8 (Art. ID: e43245), Public Library of Science, USA, pp. 1-15.

Schuelein, R., Everingham, P., Kwok-Schuelein, T., 2011, Integrin-mediated type IV secretion by Helicobacter: What makes it tick?, Trends in Microbiology [P], vol 19, issue 5, Elsevier Ltd, UK, pp. 211-216.

Srikhanta, Y.N., Gorrell, R.J., Steen, J.A., Gawthorne, J.A., Kwok-Scheulein, T., Grimmond, S.M., Robins-Browne, R.M., Jennings, M.P., 2011, Phasevarion mediated epigenetic gene regulation in Helicobacter pylori, PLoS ONE [P], vol 6, issue 12 (Art. No: e27569), Public Library of Science, USA, pp. 1-9.

Palframan, S.L., Kwok-Scheulein, T., Gabriel, K., 2011, Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis, Frontiers in Cellular and Infection Microbiology [E], vol 2, issue Art. No.: 92, Frontiers Research Foundation, Switzerland, pp. 1-9.

Foo, J.H., Culvenor, J., Ferrero, R.L., Kwok-Schuelein, T., Lithgow, T.J., Gabriel, K., 2010, Both the p33 and p55 subunits of the Helicobacter pylori VacA toxin are targeted to mammalian mitochondria, Journal of Molecular Biology [P], vol 401, issue 5, Academic Press, UK, pp. 792-798.

Hutton, M., Liaskos, M., Turner, L., Cardona, A., Kwok-Schuelein, T., Ferrero, R., 2010, Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells, Infection And Immunity [P], vol 78, issue 11, American Society for Microbiology, United States, pp. 4523-4531.

Kwok-Scheulein, T., Helfer, H., Alam, M.I., Heinrich, J., Pavlovic, J., Moelling, K., 2009, Inhibition of influenza A virus replication by short double-stranded oligodeoxynucleotides, Archives Of Virology [P], vol 154, issue 1, Springer Wein, Austria, pp. 109-114.

Kwok-Scheulein, T., Heinrich, J., Jung-Shiu, J., Meier, M.G., Mathur, S., Moelling, K., 2009, Reduction of gene expression by a hairpin-loop structured oligodeoxynucleotide: alternative to siRNA and antisense, Biochimica et Biophysica Acta [P], vol 1790, issue 10, Elsevier BV, The Netherlands, pp. 1170-1178.

Verger, D., Carr, P.D., Kwok-Schuelein, T., Ollis, D.L., 2007, Crystal structure of the N-terminal domain of the TyrR transcription factor responsible for gene regulation of aromatic amino acid biosynthesis and transport in Escherichia coli K12, Journal of Molecular Biology, vol 367, issue 1, Academic Press, UK, pp. 102-112.

Kwok-Schuelein, T., Zabler, D., Urman, S., Rohde, M., Hartig, R., Wessler, S., Misselwitz, R., Berger, J., Sewald, N., Konig, W., Backert, S., 2007, Helicobacter exploits integrin for type IV secretion and kinase activation, Nature, vol 449, issue 7164, Nature Publishing Group, UK, pp. 862-866.

Backert, S., Kwok-Schuelein, T., Konig, W., 2005, Conjugative plasmid DNA transfer in Helicobacter pylori mediated by chromosomally encoded relaxase and TraG-like proteins, Microbiology, vol 151, issue 11, Society for General Microbiology, UK, pp. 3493-3503.

Backert, S., Gressmann, H., Kwok-Schuelein, T., Zimny-Arndt, U., Konig, W., Jungblut, P.R., Meyer, T.F., 2005, Gene expression and protein profiling of AGS gastric epithelial cells upon infection with Helicobacterpylori, Proteomics, vol 5, issue 15, Wiley - VCH Verlag GmbH & Co. KGaA, Germany, pp. 3902-3918.

Brandt, S., Kwok-Schuelein, T., Hartig, R., Konig, W., Backert, S., 2005, NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein, Proceedings of the National Academy of Sciences of the United States of America, vol 102, issue 26, National Academy of Sciences, USA, pp. 9300-9305.

Backert, S., Kwok-Schuelein, T., Schmid, M., Selbach, M., Moese, S., Peek Jr., R.M., Konig, W., Meyer, T.F., Jungblut, P.R., 2005, Subproteomes of soluble and structure-bound Helicobacter pylori proteins analyzed by two-dimensional gel electrophoresis and mass spectrometry, Proteomics, vol 5, issue 5, Wiley - VCH Verlag GmbH & Co. KGaA, Germany, pp. 1331-1345.

Konig, W., Lauf, H., Tammer, I., Ghebremedhin, B., Clarici, A., Thies, F.L., Drynda, A., Schmalcz, A., Kwok-Schuelein, T., Arnold, R., Backert, S., Werchau, H., Konig, B., 2004, Innate and adaptive immunity of the respiratory tract - The role of microbial factors for host defense and sensitization - Part I | [Naturliche und adaptive immunitat des respirationstraktes - Bedeutung mikrobieller faktoren fur infektabwehr und sen, Atemwegs- und Lungenkrankheiten, vol 30, issue 11, Dustri-Verlag Dr. Karl Feistle, Germany, pp. 551-568.

Backert, S., Schwarz, T., Miehlke, S., Kirsch, C., Sommer, C., Kwok-Schuelein, T., Gerhard, M., Goebel, U.B., Lehn, N., Konig, W., Meyer, T.F., 2004, Functional analysis of the cag pathogenicity island in Helicobacter pylori isolates from patients with gastritis, peptic ulcer, and gastric cancer, Infection and Immunity, vol 72, issue 2, American Society for Microbiology, USA, pp. 1043-1056.

Moese, S., Selbach, M., Kwok-Schuelein, T., Brinkmann, V., Konig, W., Meyer, T.F., Backert, S., 2004, Helicobacter pylori Induces AGS cell motility and elongation via independent signaling pathways, Infection and Immunity, vol 72, issue 6, American Society for Microbiology, USA, pp. 3646-3649.

Kwok-Schuelein, T., Backert, S., Schwarz, H., Berger, J., Meyer, T.F., 2002, Specific entry of Helicobacter pylori into cultured gastric epithelial cells via a zipper-like mechanism, Infection and Immunity, vol 70, issue 4, American Society for Microbiology, USA, pp. 2108-2120.

Conference Proceedings

Kwok-Schuelein, T., Konig, W., Backert, S., 2005, GLV003: Invasion of Helicobacter pylori into gastric epithelial cells: a potential determinant of virulence, persistence and treatment failures, `56 Tagung der Deutschen Gesellschaft fur Hygiene und Mikrobiologie (26?29. September 2004, Munster), 26/9/2008 to 29/9/2004, Urban and Fischer Verlag, Germany, pp. 129-132.

Other

Moelling, K., Matskevich, A., Elzaouk, L., Heinrich, J., Jung, J.S., Kwok-Schuelein, T., Mathur, S., 2006, Self-inactivation of HIV by its own RT/RNase H, ORAL PRESENTATION from the 2006 International Meeting of The Institute of Human Virology, Baltimore, USA. 17-21 November, 2006, BioMed Central Ltd, UK, USA & The Netherlands.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Bacterial flagellar motor: how is the power-generating part assembled and activated?.

Supervisors:

Roujeinikova, A (Main), Kwok-Schuelein, T (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Helicobacter pylori Vacuolating cytotoxin (VacA) - examining its role at mitochondria.

Supervisors:

Gabriel, K (Joint-co), Kwok-Schuelein, T (Joint), Lithgow, T (Associate).

Program of Study:

(MASTER'S BY RESEARCH).

Thesis Title:

Investigating the role of Helicobacter pylori in E-cadherin regulation and epithelial to mesenchymal transition events .

Supervisors:

Kwok-Schuelein, T (Main), Lithgow, T (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Modulation of host proinflammatory responses by the type IV secretion system of Helicobacter pylori.

Supervisors:

Kwok-Schuelein, T (Main), Devenish, R (Associate), Gong, L (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Structural and functional characterisation of the Helicobacter pylori type IV secretion system.

Supervisors:

Kwok-Schuelein, T (Main), Lithgow, T (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Structural and functional characterization of the Helicobacter pylori protein CagA.

Supervisors:

Roujeinikova, A (Main), Kwok-Schuelein, T (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Structure and character of helicobacter outer membrane proteins.

Supervisors:

Kwok-Schuelein, T (Joint-co), Perry, A (Joint).