Dr Emma Jones - Researcher Profile

Biography

Emma works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Lecturer.

Qualifications

PHD

Institution: Monash University

Year awarded: 2005

BACHELOR OF SCIENCE (HONS)

Institution: Monash University

Year awarded: 2000

ARTS (PHARMACOLOGY)

Institution: Monash University

Year awarded: 1999

Publications

Journal Articles

McCarthy, C.A., Widdop, R.E., Denton, K.M., Jones, E.S., 2013, Update on the Angiotensin AT(2) Receptor, Current Hypertension Reports [P], vol 15, issue 1, Springer Healthcare, USA, pp. 25-30.

Bosnyak, S., Widdop, R.E., Denton, K.M., Jones, E.S., 2012, Differential mechanisms of ang (1-7)-mediated vasodepressor effect in adult and aged candesartan-treated rats, International Journal of Hypertension [E], vol 2012, issue 192567, Hindawi Publishing Corporation, USA, pp. 1-9.

Gaspari, T.A., Vinh, A., Jones, E.S., Widdop, R.E., 2012, Ganging up on Angiotensin II Type 1 Receptors in Vascular Remodeling, Hypertension [P], vol 60, issue 1, Lippincott Williams & Wilkins, USA, pp. 17-19.

Jones, E.S., Black, M.J., Widdop, R.E., 2012, Influence of Angiotensin II Subtype 2 Receptor (AT(2)R) Antagonist, PD123319, on Cardiovascular Remodelling of Aged Spontaneously Hypertensive Rats during Chronic Angiotensin II Subtype 1 Receptor (AT(1)R) Blockade, International Journal of Hypertension [E], vol 2012, issue 543062, Hindawi Publishing Corporation, USA, pp. 1-11.

Lee, S., Brait, V.H., Arumugam, T., Evans, M., Kim, H.H.A., Widdop, R.E., Drummond, G.R., Sobey, C.G., Jones, E.S., 2012, Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo, Experimental & Translational Stroke Medicine [E], vol 4, issue 1 (Art. No.: 16), BioMed Central Ltd, UK, pp. 1-9.

Chan, C., Moore, J., Budzyn, K., Guida, E., Diep, H., Vinh, A., Jones, E.S., Widdop, R.E., Armitage, J.A., Sakkal, S., Ricardo, S.D., Sobey, C.G., Drummond, G.R., 2012, Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice, Hypertension [P], vol 60, issue 5, Lippincott Williams & Wilkins, USA, pp. 1207-1212.

Hilliard, L.M., Jones, E.S., Steckelings, U.M., Unger, T., Widdop, R.E., Denton, K.M., 2012, Sex-specific influence of angiotensin type 2 receptor stimulation on renal function: a novel therapeutic target for hypertension, Hypertension [P], vol 59, issue 2, Lippincott Williams & Wilkins, USA, pp. 409-414.

Jones, E.S., Del Borgo, M.P., Kirsch, J., Clayton, D.J., Bosnyak, S., Welungoda, I.K., Hausler, N., Unabia, S., Perlmutter, P., Thomas, W.G., Aguilar, M.I., Widdop, R.E., 2011, A single beta-amino acid substitution to angiotensin II confers AT2 receptor selectivity and vascular function, Hypertension [P], vol 57, issue 3, Lippincott Williams & Wilkins, USA, pp. 570-576.

Steckelings, U., Larhed, M., Hallberg, A., Widdop, R., Jones, E., Wallinder, C., Namsolleck, P., Dahlof, B., Unger, T., 2011, Non-peptide AT2-receptor agonists, Current Opinion in Pharmacology [P], vol 11, issue 2, Elsevier Ltd. * Current Opinion Journals, UK, pp. 187-192.

Bosnyak, S., Jones, E., Christopoulos, A., Aguilar, M., Thomas, W., Widdop, R., 2011, Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors, Clinical Science [P], vol 121, issue 7, Portland Press Ltd, UK, pp. 297-303.

Brown, R.D., Hilliard, L.M., Head, G.A., Jones, E.S., Widdop, R.E., Denton, K.M., 2011, Sex differences in the pressor and tubuloglomerular feedback response to angiotensin II, Hypertension [P], vol E, Lippincott Williams & Wilkins, USA, pp. 1-7.

Kleinschnitz, C., Grund, H., Wingler, K., Armitage, M.E., Jones, E.S., Mittal, M., Barit, D., Schwarz, T., Geis, C., Kraft, P., Barthel, K., Schuhmann, M.K., Herrmann, A.M., Meuth, S.G., Stoll, G., Meurer, S., Schrewe, A., Becker, L., Gailus-Durner, V., Fuchs, H., Klopstock, T., de Angelis, M.H., Jandeleit-Dahm, K.A., Shah, A.M., Weissmann, N., Schmidt, H.H.H., 2010, Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration, Plos Biology [P], vol 8, issue 9 (e1000479), Public Library of Science, USA, pp. 1-13.

Bosnyak, S., Welungoda, I.K., Hallberg, A., Alterman, M., Widdop, R.E., Jones, E.S., 2010, Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats, British Journal of Pharmacology [P], vol 159, issue 3, John Wiley & Sons Ltd, UK, pp. 709-716.

Vinh, A., Gaspari, T.A., Jones, E.S., Widdop, R.E., 2009, Functional Cardiovascular Effects of Angiotensin Peptides: Focus on Atherosclerosis and Hypertension, Current Hypertension Reviews [P], vol 5, issue 3, Bentham Science Publishers Ltd, The Netherlands, pp. 227-236.

Jones, E.S., Vinh, A., McCarthy, C.A., Gaspari, T.A., Widdop, R.E., 2008, AT2 receptors: Functional relevance in cardiovascular disease, Pharmacology & Therapeutics, vol 120, issue 3, Elsevier Inc., United States, pp. 292-316.

Sampson, A.K., Moritz, K.M., Jones, E.S., Flower, R.L., Widdop, R.E., Denton, K.M., 2008, Enhanced angiotensin II type 2 receptor mechanisms mediate decreases in arterial pressure attributable to chronic low-dose angiotensin II in female rats, Hypertension, vol 52, issue 4, Lippincott Williams & Wilkins, United States, pp. 666-671.

Widdop, R.E., Vinh, A., Henrion, D., Jones, E.S., 2008, Vascular angiotensin AT2 receptors in hypertension and ageing, Clinical and Experimental Pharmacology & Physiology, vol 35, issue 4, Wiley-Blackwell Publishing Asia, Australia, pp. 386-390.

Jones, E.S., Black, M.J., Widdop, R.E., 2004, Angiotensin AT2 receptor contributes to cardiovascular remodelling of aged rats during chronic AT1 receptor blockade, Journal of Molecular and Cellular Cardiology, vol 37, issue 5, Academic Press, UK, pp. 1023-1030.

Widdop, R.E., Jones, E.S., Hannan, R.E., Gaspari, T.A., 2003, Angiotensin AT2 receptors: cardiovascular hope or hype?, British Journal of Pharmacology, vol 140, issue 5, Nature Publishing Group, London England, pp. 809-824.

Conference Proceedings

Jones, E.S., Paull, J.R., Widdop, R.E., 1999, Does stimulation of the angiotensin AT2 receptor contribute to the antihypertensive effect of AT1 receptor antagonists in salt-restricted rats, Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists, Sydney, NSW, Dec 1999, ASCEPT, Sydney NSW Australia, pp. 84-Post 1-23.

Postgraduate Research Supervisions

Completed Supervision

Student:

Bosnyak, S.

Program of Study:

Cardiovascular studies of AT2 receptor in various pathophysiological settings. (PHD) 2011.

Supervisors:

Widdop, R (Main), Jones, E (Associate).