Prof Graham Jenkin - Researcher Profile

Biography

Using medical and networking skills to put research into practice

With interests ranging from bones to babies and early IVF involvement, Professor Graham Jenkin is a busy man who likes to get things done. He’s guiding research into antioxidant and stem cell therapies for at-risk babies, working with Mesoblast Ltd to commercialise a stem cell treatment for damaged backs and using his IVF expertise to help endangered species.

As an honorary professor of obstetrics and gynaecology, holder of a personal chair and deputy director of the Ritchie Centre at the Monash Institute of Medical Research (MIMR), clearly Graham has form.

He describes himself as a “Jack of all trades and master of none”, which is, of course, not true. He’s a master of reproductive physiology – his specialty – and networking.

“I love my research,” he says, “but I realise that it has to have translation. So, networking within Monash and outside to bring in commercial organisations is very important.”

Graham’s networking talents were recognised in 2009 when he won the Vice Chancellor’s Award for Excellence in Innovation and Collaboration in Research with Industry. 

He was honoured for his work with biomedical company Mesoblast, founded by Monash medical graduate Sylviu Itescu (now a listed Australian company), which is working with a diverse team that Graham put together to perfect an adult stem cell treatment for damaged spinal disks.

The work involves Monash engineers and CSIRO scientist Jerome Werkmeister, who are creating a biodegradable matrix, or scaffold, on which to grow cartilage from mesenchymal progenitor cells (MPC), developed by Mesoblast. 

“The trick is to get a matrix that is strong enough to keep two vertebrae apart, while cartilage forms, but then able to degrade in a specific way,” he says.

The MPC cells are derived from adult stem cells, found in bone marrow and fat, which typically turn into cartilage and then bone. Graham’s team is getting them to stop before the bone stage, just as they’ve become tough but flexible enough for disk repair.

Their treatment also uses patented sound acoustic wave (SAW) technology, developed by Monash mechanical engineers Professor James Friend and Associate Professor Leslie Yeo, to force MPCs deep into scaffolds to get stronger and more even repairs.

 

• Read the rest of the profile

Qualifications

DOCTOR OF PHILOSOPHY

Institution: Cantab

Year awarded: 2005

PHD

Institution: Cambridge University

Year awarded: 1975

Publications

Book Chapters

Young, I., Renfree, M., Mesiano, S., Shaw, G., Jenkin, G., Smith, R., 2011, The comparative physiology of parturition in mammals: hormones and parturition in mammals, in Hormones and Reproduction of Vertebrates - Volume 5: Mammals, eds David O. Norris and Kristin H. Lopez, Academic Press, United States, pp. 95-116.

Murphy, S., Rosli, S., Acharya, R., Mathias, L., Lim, R., Wallace, E., Jenkin, G., 2010, Amnion epithelial cell isolation and characterization for clinical use, in Current Protocols in Stem Cell Biology, eds Andrew Elfanty, Richard Gregory, Roger Patient, Thorsten Schlager, Evan Y. Snyder, Yukiko Yamashita, John Wiley & Sons, United States, pp. 1-25.

Murphy, S., Wallace, E., Jenkin, G., 2010, Placental-Derived Stem Cells: Potential Clinical Applications, in Stem Cells & Regerative Medicine: From Molecular Embryology to Tissue Engineering, eds Krishnarao Appasani & Raghu K. Appasani, Humana Press, New York, pp. 243-263.

Journal Articles

Hodges, R., Lim, R., Jenkin, G., Wallace, E., 2012, Amnion epithelial cells as a candidate therapy for acute and chronic lung injury, Stem Cells International [E], vol 2012, issue Art Id 709763, Hindawi Publishing Corporation, United States, pp. 1-7.

Miller, S.L., Sutherland, A.E., Supramaniam, V.G., Walker, D.W., Jenkin, G., Wallace, E.M., 2012, Antenatal glucocorticoids reduce growth in appropriately grown and growth-restricted ovine fetuses in a sex-specific manner, Reproduction, Fertility and Development [P], vol 24, issue 5, C S I R O Publishing, Australia, pp. 753-758.

Milton, P., Dickinson, H., Jenkin, G., Lim, R., 2012, Assessment of Respiratory Physiology of C57BL/6 Mice following Bleomycin Administration Using Barometric Plethysmography, Respiration [P], vol 83, issue 3, Karger, Switzerland, pp. 1-14.

Tare, M., Miller, S.L., Wallace, E.M., Sutherland, A.E., Yawno, T., Coleman, H.A., Jenkin, G., Parkington, H.C., 2012, Glucocorticoid treatment does not alter early cardiac adaptations to growth restriction in preterm sheep fetuses, Bjog-An International Journal Of Obstetrics And Gynaecology [P], vol 119, issue 8, Wiley-Blackwell Publishing Ltd, UK, pp. 906-914.

Murphy, S., Shiyun, S.C., Tan, J., Chan, S.T., Jenkin, G., Wallace, E.M., Lim, R.S.W., 2012, Human amnion epithelial cells do not abrogate pulmonary fibrosis in mice with impaired macrophage function, Cell Transplantation [P], vol 21, issue 7, Cognizant Communication Corporation, United States, pp. 1477-1492.

Murphy, S., Lim, R.S.W., Heraud, P.R., Cholewa, M., Le Gros, M.A., de Jong, M.D., Howard, D., Paterson, D.J., McDonald, C., Atala, A., Jenkin, G., Wallace, E.M., 2012, Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator, PLoS ONE [P], vol 7, issue 9 (Art. ID: e46533), Public Library Of Science, United States, pp. 1-8.

Hodges, R., Jenkin, G., Hooper, S., Allison, B., Lim, R., Dickinson, H., Miller, S., Vosdoganes, P., Wallace, E., 2012, Human amnion epithelial cells reduce ventilation-induced preterm lung injury in fetal sheep , American Journal Of Obstetrics And Gynecology [P], vol 206, issue 5 (Art. No.: 448), Mosby Inc., United States, pp. 8-15.

Oehme, D., Goldschlager, T., Rosenfeld, J.V., Danks, A., Ghosh, P., Gibbon, A., Jenkin, G., 2012, Lateral surgical approach to lumbar intervertebral discs in an ovine model, The Scientific World Journal [P], vol 2012, issue Art. No.: 873726, Hindawi Publishing Corporation, United States, pp. 1-5.

Sutherland, A., Crossley, K., Allison, B., Jenkin, G., Wallace, E., Miller, S., 2012, The effects of intrauterine growth restriction and antenatal glucocorticoids on ovine fetal lung development, Pediatric Research [P], vol 71, issue 6, Nature Publishing Group, United States, pp. 689-696.

Dickinson, H., Milton, P., Jenkin, G., 2012, The isolation and characterization of putative mesenchymal stem cells from the spiny mouse, Cytotechnology [P], vol 64, issue 5, Springer Netherlands, Netherlands, pp. 591-599.

Goldschlager, T., Ghosh, P., Zannettino, A., Williamson, M.M., Rosenfeld, J.V., Itescu, S., Jenkin, G., 2011, A comparison of mesenchymal precursor cells and amnion epithelial cells for enhancing cervical interbody fusion in an ovine model, Neurosurgery [P], vol 68, issue 4, Lippincott Williams & Wilkins, USA, pp. 1025-1034.

Bertucci, M.C., Loose, J.M., Wallace, E.M., Jenkin, G., Miller, S.L., 2011, Anti-inflammatory therapy in an ovine model of fetal hypoxia induced by single umbilical artery ligation, Reproduction, Fertility and Development [P], vol 23, issue 2, CSIRO Publishing, Australia, pp. 346-352.

Goldschlager, T., Rosenfeld, J.V., Ghosh, P., Itescu, S., Blecher, C., McLean, C., Jenkin, G., 2011, Cervical interbody fusion is enhanced by allogeneic mesenchymal precursor cells in an ovine model, Spine [P], vol 36, issue 8, Lippincott Williams & Wilkins, USA, pp. 615-623.

Murphy, S., Lim, R., Dickinson, H., Acharya, R., Rosli, S., Jenkin, G., Wallace, E., 2011, Human amnion epithelial cells prevent bleomycin-induced lung injury and preserve lung function, Cell Transplantation [P], vol 20, issue 6, Cognizant Communication Corp., United States, pp. 909-923.

Goldschlager, T., Ghosh, P., Zannettino, A., Gronthos, S., Rosenfeld, J.V., Itescu, S., Jenkin, G., 2010, Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model., Neurosurgical focus [electronic resource] [P], vol 28, issue 6 (E4), American Association of Neurological Surgeons, USA, pp. 1-8.

Moodley, Y., Ilancheran, S., Samuel, C., Vaghjiani, V., Atienza, D., Williams, E., Jenkin, G., Wallace, E.M., Trounson, A.O., Manuelpillai, U.C., 2010, Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair, American Journal Of Respiratory And Critical Care Medicine [P], vol 182, issue 5, American Thoracic Society, USA, pp. 643-651.

Goldschlager, T., Jenkin, G., Ghosh, P., Rosenfeld, J.V., Zannettino, A., 2010, Potential Applications for Using Stem Cells in Spine Surgery, Current Stem Cell Research and Therapy [P], vol 5, issue 4, Bentham Science Publishers Ltd, Netherlands, pp. 345-355.

Guo, J., Tecirlioglu, R.T., Nguyen, L.T., Koh, K.L., Jenkin, G., Trounson, A.O., 2010, Reprogramming factors involved in hybrids and cybrids of human embryonic stem cells fused with hepatocytes, Cellular Reprogramming [P], vol 12, issue 5, Mary Ann Liebert Inc Publishers, USA, pp. 529-541.

Goldschlager, T., Abdelkader, A., Kerr, J.B., Boundy, I., Jenkin, G., 2010, Undecalcified bone preparation for histology, histomorphometry and fluorochrome analysis, Journal of Visualized Experiments [E], vol 35, issue 1707, Journal of Visualized Experiments, USA, pp. 1-3.

Goldschlager, T., Rosenfeld, J.V., Young, I.R., Jenkin, G., 2009, Anterior cervical discectomy and fusion in the ovine model, Journal of Visualized Experiments [E], vol E, Journal of Visualized Experiments, US, pp. 1-10.

Miller, S.L., Supramaniam, V.G., Jenkin, G., Walker, D.W., Wallace, E.M., 2009, Cardiovascular responses to maternal betamethasone administration in the intrauterine growth-restricted ovine fetus, American Journal Of Obstetrics And Gynecology [P], vol 201, issue 6, Mosby, Inc., USA, pp. 613.e1-613.e8.

Goldschlager, T., Rosenfeld, J., Jenkin, G., Ghosh, P., 2009, Chondrogenic differentiation of adipose-derived stem cells, ANZ Journal of Surgery [P], vol 79, issue 11, Wiley-Blackwell Publishing, Australia, pp. 856-857.

Jenkin, G., Challis, J., Robinson, J., Young, I., 2009, Geoffrey Donald Thorburn 1930-1996, Historical Records of Australian Science [P], vol 20, issue 1, CSIRO Publishing, Australia, pp. 109-130.

Miller, S.L., Loose, J.M., Jenkin, G., Wallace, E.M., 2009, The effects of sildenafil citrate (Viagra) on uterine blood flow and well being in the intrauterine growth-restricted fetus, American Journal of Obstetrics and Gynecology, vol 200, issue 1, Mosby, Inc., USA, pp. 102.e1-102.e7.

Dickinson, H., Griffiths, T., Walker, D.W., Jenkin, G., 2008, Application of clinical indices of fetal growth and wellbeing to a novel laboratory species, the spiny mouse, Reproductive Biology, vol 8, issue 3, Towarzystwo Biologil Rozrodu, Poland, pp. 229-243.

Jones, G.M., Cram, D.S., Song, B., Magli, C., Gianaroli, L., Lacham, O., Findlay, J.K., Jenkin, G., Trounson, A.O., 2008, Gene expression profiling of human oocytes following in vivo or in vitro maturation, Human Reproduction, vol 23, issue 5, Oxford University Press, UK, pp. 1138-1144.

Rodricks, C.L., Gibbs, M.E., Jenkin, G., Miller, S.L., 2008, The effect of hypoxia at different embryonic ages on impairment of memory ability in chicks, International Journal of Developmental Neuroscience, vol 26, Pergamon-Elsevier Science Ltd, Oxford England UK, pp. 113-118.

Miller, S.L., Chai, M., Loose, J.M., Castillo-Melendez, M., Walker, D.W., Jenkin, G., Wallace, E.M., 2007, The effects of maternal betamethasone administration on the intrauterine growth-restricted fetus, Endocrinology, vol 148, issue 3, The Endocrine Society, Chevy Chase USA, pp. 1288-1295.

Supramaniam, V.G., Jenkin, G., Loose, J.M., Wallace, E.M., Miller, S.L., 2006, Chronic fetal hypoxia increases activin A concentrations in the late-pregnant sheep, BJOG-An International Journal of Obstetrics and Gynaecology, vol 113, issue 1, Blackwell Publishing, Oxford England, pp. 102-109.

Bott, E.M., Young, I.R., Jenkin, G., McLaren, W.J., 2006, Detection of morphological changes of the ovine cervix in response to sex steroids using a fluorescence confocal endomicroscope, American Journal of Obstetrics and Gynecology, vol 194, issue 1, Mosby, Inc., St Louis USA, pp. 105-112.

Yang, H.Y., Cox, S., Jenkin, G., Findlay, J.K., Trounson, A.O., Shaw, J.M., 2006, Graft site and gonadotrophin stimulation influences the number and quality of oocytes from murine ovarian tissue grafts, Reproduction, vol 131, issue 5, BioScientifica Ltd., UK, pp. 851-859.

Rodricks, C.L., Miller, S.L., Jenkin, G., Gibbs, M.E., 2006, The role of corticosterone in prehatch-induced memory deficits in chicks, Brain Research, vol 1123, Elsevier Science BV, Amsterdam The Netherlands, pp. 34-41.

McClure, L., O'Connor, A.E., Hayward, S., Jenkin, G., Walker, D.W., Phillips, D.J., 2005, Effects of age and pregnancy on the circulatory activin response of sheep to acute inflammatory challenge by lipopolysaccharide, Journal of Endocrinology, vol 185, issue 1, Society for Endocrinology, UK, pp. 139-149.

Miller, S.L., Yan, E.B., Castillo-Melendez, M.E., Jenkin, G., Walker, D.W., 2005, Melatonin provides neuroprotection in the late-gestation fetal sheep brain in response to umbilical cord occlusion, Developmental Neuroscience, vol 27, issue 2-4, S Karger AG, Switzerland, pp. 200-210.

Smith, R.P., Miller, S.L., Igosheva, N., Peebles, N., Glover, V.M., Jenkin, G., Hanson, M.A., Fisk, N.M., 2004, Cardiovascular and endocrine responses to cutaneous electrical stimulation after fentanyl in the ovine fetus, American Journal of Obstetrics and Gynecology, vol 3, issue 190, Mosby, Inc, USA, pp. 836-842.

Loose, J.M., Miller, S.L., Supramaniam, V.G., Ward, J.W.A., O'Connor, A.E., de Kretser, D.M., Wallace, E.M., Jenkin, G., 2004, Hypoxia induced activin secretion by the fetoplacental unit: differential responses related to gestation. IF 2.171, British Journal of Obstetrics and Gynaecology, vol 111, Blackwell Publishing, Oxford England, pp. 1346-1352.

Jenkin, G., Young, I.R., 2004, Mechanisms responsible for parturition; the use of experimental models, Animal Reproduction Science, vol 82-83, Elsevier, Amsterdam The Netherland, pp. 567-581.

Waterhouse, T.A., Cox, S., Snow, M.J., Jenkin, G., Shaw, J.M., 2004, Offspring produced from heterotopic ovarian allografts in male and female recipient mice, Reproduction, vol 127, issue 6, Bioscientifica Ltd, UK, pp. 689-694.

Supramaniam, V.G., Jenkin, G., Wallace, E.M., O'Connor, A.E., de Kretser, D.M., Miller, S.L., 2004, The effect of graded hypoxia on activin A, PGE2 and cortisol levels in the late pregnant sheep, Reproduction Fertility and Development:15, 625 - 632, vol 16, CSIRO Publishing, Collingwood Vic Australia, pp. 625-632.

Rodricks, C.L., Rose, I.A., Camm, E.J., Jenkin, G., Miller, S.L., Gibbs, M.E., 2004, The effect of prenatal hypoxia and malnutrition on memory consolidation in the chick, Developmental Brain Research, vol 148, issue 1, Elsevier, Amsterdam The Netherlands, pp. 113-119.

Cleary, M.L., Paris, M.C., Shaw, J.M., Jenkin, G., Trounson, A.O., 2003, Effect of ovariectomy and graft position on cryopreserved common wombat (Vombatus ursinus) ovarian tissue following xenografting to nude mice. CN 5 IF3.136, Reproduction, Fertility and Development, vol 15, CSIRO Publishing, UK, pp. 333-342.

Snow, M.J., Cox, S., Jenkin, G., Shaw, J.M., 2003, Fertility of mice following receipt of ovaries slow cooled in dimethyl sulphoxide or ethylene glycol is largely independent of cryopreservation equilibration time and temperature, Reproduction, Fertility and Development, vol 15, issue 8, CSIRO Publishing, Collingwood Vic Australia, pp. 407-414.

Grigsby, P.L., Hirst, J.J., Scheerlinck, J.Y., Phillips, D.J., Jenkin, G., 2003, Fetal responses to maternal and intra-amniotic lipopolysaccharide administration in sheep, Biology of Reproduction, vol 68, issue 5, Society for the Study of Reproduction Inc., Madison USA, pp. 1695-1702.

Cleary, M.L., West, M., Shaw, J.M., Jenkin, G., Trounson, A.O., 2003, In vitro maturation of oocytes from non-stimulated common wombats, Reproduction, Fertility and Development, vol 15, issue 5, CSIRO Publishing, Collingwood Vic Australia, pp. 303-310.

Wallace, E.M., Schneider-Kolsky, M.E., Edwards, A., Baker, L., Jenkin, G., 2003, Maternal serum activin A levels are increased in association with intrauterine fetal growth restriction., British Journal of Obstetrics and Gynaecology, vol 110, issue 3, Blackwell Publishing, UK, pp. 306-310.

Wallace, E.M., Schneider-Kolsky, M.E., Edwards, A., Baker, L.S., Jenkin, G., 2003, Maternal serum activin A levels in association with intrauterine fetal growth restriction, BJOG - an International Journal of Obstetrics and Gynaecology, vol 110, issue 3, Wiley-Blackwell Publishing Ltd., Amsterdam Netherlands, pp. 306-310.

Grigsby, P.L., Hirst, J.J., Scheerlinck, J., Phillips, D.J., Jenkin, G., 2002, Fetal responses to maternal and intra-amniotic lipopolysaccharide administration in sheep: Inflammatory challenges during pregnancy, Biology of Reproduction, vol 68, issue 1, Society for the Study of Reproduction, Madison USA - Online, pp. 1-32.

Snow, M.J., Cox, S., Jenkin, G., Trounson, A.O., Shaw, J.M., 2002, Generation of Live Young from Xenografted Mouse Ovaries, Science, vol 297, issue 5590, American Association for the Advancement of Science, Washington DC USA, p. 2227.

Snow, M.J., Cleary, M.L., Cox, S., Shaw, J.M., Paris, M.C., Jenkin, G., 2001, Comparison of the effects of in vitro and in situ storage on the viability of mouse ovarian tissue collected after death, Reproduction Fertility and Development, vol 13, issue 5-Jun, CSIRO Publishing, Collingwood Vic Australia, pp. 389-394.

Cleary, M.L., Snow, M.J., Paris, M.C.J., Shaw, J.M., Cox, S., Jenkin, G., 2001, Cryopreservation of mouse ovarian tissue following prolonged exposure to an ischemic environment, Cryobiology, vol 42, Academic Press inc, San Diego California USA, pp. 121-133.

Jenkin, G., Ward, J.N.A., Hooper, S.B., O'Connor, A., de Kretser, D.M., Wallace, E.M., 2001, Feto-placental hypoxemia regulates the release of fetal activin A and prostaglandin E2, Endocrinology, vol 142, issue 2, Endocrine Society, Bethesda USA, pp. 963-966.

Wolvekamp, M.C.J., Cleary, M.L., Cox, S., Shaw, J.M., Jenkin, G., Trounson, A.O., 2001, Follicular development in cryopreserved common wombat ovarian tissue xenografted to nude rats, Animal Reproduction Science, vol 65, Elsevier Science BV, Amsterdam Netherlands, pp. 135-147.

Scott, J.E., Grigsby, P.L., Hirst, J.J., Jenkin, G., 2001, Inhibition of prostaglandin synthesis and its effect on uterine activity during established premature labor in sheep, Journal of the Society for Gynecologic Investigation, vol 8, issue 5, Elsevier, New York USA, pp. 266-276.

Jenkin, G., Ward, J.W.A., Loose, J.M., Schneider-Kolsky, M.E., Young, I., Canny, B., O'Connor, A., de Kretser, D.M., Wallace, E.M., 2001, Physiological and regulatory roles of activin A in late pregnancy, Molecular and Cellular Endocrinology, vol 180, Elsevier Science Ireland Ltd, Ireland, pp. 131-138.

Miller, S., Jenkin, G., Walker, D.M., 2000, Effects of hyperthermia on uterine blood flow and shunting through uterine arteriovenous anastomoses in the late-pregnant ewe, Reproduction Fertility and Development, vol 11 issue 45, CSIRO Publications, Melbourne Vic Australia, pp. 201-209.

Al-Matubsi, H.Y., Fraser, S.F., Fairclough, R.J., Jenkin, G., 2000, Effects of progesterone on expression of messenger RNA encoding oxytocin-neurophysin, oxytocin receptor and prostaglandin G/H synthase-1 and -2 during the early oestrous cycle in the ovine corpus luteum, Reproduction, Fertility and Development, vol 11 issue 7 & 8, CSIRO Publishing, Melbourne Vic Australia, pp. 435-442.

Shaw, J.M., Cox, S., Trounson, A.O., Jenkin, G., 2000, Evaluation of the long-term function of cryopreserved ovarian grafts in the mouse, implications for human applications, Molecular and Cellular Endocrinology, vol 161, Elsevier Science Ltd, Co Clare Ireland, pp. 103-110.

Cox, S., Shaw, J.M., Jenkin, G., 2000, Follicular development in transplanted fetal and neonatal mouse ovaries is influenced by the gonadal status of the adult recipient, Fertility and sterility, vol 74 issue 2, Elsevier Science Inc, New York NY USA, pp. 366-371.

Imthurn, B., Cox, S., Jenkin, G., Trounson, A.O., Shaw, J.M., 2000, Gonadotrophin administration can benefit ovarian tissue grafted to the body wall: implications for human ovarian grafting, Molecular and Cellular Endocrinology, vol 163, Elsevier Science Ltd, Co Clare Ireland, pp. 141-146.

Grigsby, P.L., Poore, K.R., Hirst, J.J., Jenkin, G., 2000, Inhibition of premature labor in sheep by a combined treatment of nimesulide, a prostaglandin synthase type 2 inhibitor, and atosiban, an oxytocin receptor antagonist, American Journal of Obstetrics and Gynecology, vol 183, Mosby/Harcourt Health, www.harcourthealth.com, pp. 649-657.

Wolvekamp, M.C.J., MacKallum, C., Cleary, M.L., Shaw, J.M., Cox, S., Jenkin, G., Trounson, A.O., 2000, Novel approach to save the critically endangered Northern Hairy-nosed wombat. IF2.161, Theriogenology, vol 53, Elsevier Science, NY USA, p. 345.

Christian, K.A., Griffiths, A.D., Bedford, G., Jenkin, G., 1999, Androgen concentrations and behaviour of frillneck lizards (Chlamydosaurus kingis), Journal of Herpetology, vol 33 issue 1, Society for the Study of Amphibians and Reptiles, St Louis MO USA, pp. 12-17.

Al-Matubsi, H.Y., Breed, W.G., Jenkin, G., Fairclough, R.J., 1999, Co-localization of Rab3B and oxytocin to electron dense granules of the sheep corpus luteum during the estrous cycle, The Anatomical Record, vol 254, Wiley-Liss (A Division of John Wiley & Sons Inc), New York NY USA, pp. 214-221.

Leung, S.T., Wathes, D.C., Young, I.R., Jenkin, G., 1999, Effect of labour induction on the expression of oxytocin receptor, cytochrome P450 aromatase and estradiol receptor in the reproductive tract of the late-pregnant ewe, Biology of Reproduction, vol 60, Society for the Study of Reproduction, Madison WI USA, pp. 814-820.

Miller, S., Jenkin, G., Walker, D.M., 1999, The effects of nitric oxide synthase inhibition on the uterine vasculature of the late pregnant ewe, American Journal of Obstetrics and Gynaecology, vol 180, Mosby-Year Book Inc, St Louis MO USA, pp. 1138-1145.

McFarlane, J.R., Foulds, L.M., O'Connor, A.E., Phillips, D.J., Jenkin, G., Hearn, M.T., de Kretser, D.M., 1999, Uterine milk production, a novel activin-binding protein, is present in ovine allantoic fluid, Endocrinology, vol 140 issue 10, The Endocrine Society, Bethesda MD USA, pp. 4745-4752.

McFarlane, J.R., Foulds, L.M., O'Conner, A., Phillips, D.J., Jenkin, G., Hearn, M.T., de Kretser, D.M., 1999, Uterine milk protein, a novel Activin Binding Protein, is present in ovine allantoic fluid, Endocrinology, vol 140, The Endocrine Society, Bethesda USA, pp. 4745-4752.

McFarlane, J.R., Foulds, L.M., O'Connor, A.E., Phillips, D.J., Jenkin, G., Hearn, M.T., de Kretser, D.M., 1999, Uterine milk protein, a novel activin-binding protein, is present in ovine allantoic fluid, Endocrinology, vol 140, issue 10, Endocrine Society, Bethesda USA, pp. 4745-4752.

Al-Matubsi, H.Y., Fairclough, R.J., Jenkin, G., 1998, Oestrogenic effects of ICI182,780a putative anti-oestrogen on the secretion of oxytocin and prostaglandin F2a during oestrous cycle in the intact ewe, Animal Reproduction Science, vol 51, Elsevier, Amsterdam Netherlands, pp. 81-96.

Foulds, L.M., de Kretser, D.M., Farnworth, P.G., Buttress, D., Jenkin, G., Groome, N.P., McFarlane, J.R., 1998, Ovine allantoic fluid contains high concentrations of activin a: partial dissociation of immunoactivity and bioactivity, BIOLOGY OF REPRODUCTION, vol 59, Society for the Study of Reproduction, MADISON WI USA, pp. 233-240.

Foulds, L.M., de Kretser, D.M., Farnworth, P.G., Buttress, D., Jenkin, G., Groome, N.P., McFarlane, J.R., 1998, Ovine allantoic fluid contains high concentrations of activinA: Partial dissociation of immunoactivity and bioactivity1, Biology of Reproduction, vol 59 (2), Society for the Study of Reproduction Inc, Madison Wisconsin USA, pp. 233-240.

Miller, S., Dickson, K.A., Jenkin, G., Walker, D.M., 1998, Physiological evidence for arterioivenous anastomoses in the unterine circulation of late pregnant ewes, Clinical and Experimental Pharmacology and Physiology, vol 25, Blackwell Science, Melbourne Vic Australia, pp. 92-98.

Al-Matubsi, H.Y., Downing, J., Jenkin, G., Fairclough, R.J., 1998, Stimulation of ovarian oxytocin secretion and uterine prostaglandin release by exogenous progesterone early in the cycle of the ovarian auto-transplanted ewe, Journal of Reproduction and Fertility, vol 112 (2), Journal of Reproduction and Fertility Ltd, Cambridge UK, pp. 279-288.

Meier, S., Trewhella, M.A., Fairclough, R.J., Jenkin, G., 1997, Changes in uterine endometrial phospholipids and fatty acids throughout the oestrous cycle and early pregnancy in the ewe, Prostaglandins, Leukotrienes and Essential Fatty Acids, vol 57, Pearson Professional Ltd, Kentville Nova Scotia Canada, pp. 341-349.

Al-Matubsi, H.Y., Downing, J., Jenkin, G., Fairclough, R.J., 1997, Effect of oestradiol on ovarian oxytocin secretion rate and luteolysis in the ewe after ovarian auto-transplantation, Reproduction, Fertility and Development, vol 9, CSIRO Australia/Australian Academy of Science, Collingwood Vic Australia, pp. 683-688.

Miller, S., Wongprasartsuk, S., Young, I.R., Wlodek, M.E., McFarlane, J.R., de Kretser, D.M., Jenkin, G., 1997, Source of Inhibin in Ovine Fetal Plasma and Amniotic Fluid, Biology of Reproduction, vol 57, Society for the Study of Reproduction, Wisconsis USA, pp. 347-353.

Miller, S., Wongprasartsuk, S., Young, I.R., Wlodek, M.E., McFarlane, J.R., de Kretser, D.M., Jenkin, G., 1997, Source of inhibin in ovine fetal plasma and amniotic fluid during late gestation: Half-life of fetal inhibin, Biology of Reproduction, vol 57, Society for the Study of Reproduction, Madison Wisconsin USA, pp. 347-353.

Conference Proceedings

Jenkin, G., Loose, J.M., Wallace, E.M., 2006, The effects of betamethasone on growth restricted ovine fetuses, Journal of The Society for Gynecologic Investigation, 22-25 March, Elsevier Science Inc, New York NY USA, p. 75A.

Ward, J., Wallace, E.M., Hooper, S.B., Jenkin, G., 1999, Activin A: a novel marker of fetal wellbeing?, Proceedings of the 3rd Annual Congress of the Perinatal Society of Australia and New Zealand, Melbourne, Victoria, 21-24 March 1999, The Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 278.

McFarlane, J.R., Xia, Y., O'Shea, T., O'Connor, A.E., Foulds, L.M., Jenkin, G., de Kretser, D.M., 1999, Follistatin levels during the estrus cycle and across gestation in merino sheep, The Endocrine Society 81st Annual Meeting Program and Abstracts, San Diego California USA 12-15 June 1999, The Endocrine Society Press, Bethesda MD USA, p. 546.

Grigsby, P.L., Poore, K.R., Hirst, J.J., Jenkin, G., 1999, Glucocorticoid-induced premature labour in sheep is inhibited by combined treatment with nimesulide and an oxytocin receptor antagonist, atosiban, Perinatal Society of Australia and New Zealand 3rd Annual Congress, Melbourne VIC 21-24 March 1999, The Perinatal Society of Australia and New Zealand, Paramatta NSW, p. 130.

Jenkin, G., Young, I.R., Wallace, E.M., de Kretser, D.M., Coghill, I.C., Canny, B., 1999, Hypoxia is a specific stimulus to fetal activin A and follistatin release in late gestation, The Endocrine Society of Australia Proceedings, Melbourne VIC 26-29 September 1999, Endocrine Society of Australia, Adelaide SA Australia, p. 134.

Schneider-Kolsky, M., Jenkin, G., Wallace, E.M., 1999, Maternal serum activin A, follistatin and prostaglandin during spontaneous human labour, Perinatal Society of Australia and New Zealand 3rd Annual Congress, Melbourne VIC 21-24 March 1999, The Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 47.

Hirst, J.J., Poore, K.R., Grigsby, P.L., Young, I.R., Jenkin, G., 1999, Use of selective inhibitors of prostaglandin synthase type-2 for delaying preterm delivery, Perinatal Society of Australia and New Zealand 3rd Annual Congress, Melbourne VIC 21-24 March 1999, The Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 4.

McFarlane, J.R., O'Shea, T., O'Connor, A.E., Jenkin, G., de Kretser, D.M., 1998, A longitudinal study of serum activin A and follistatin levels across gestation and parturition in sheep, Proceedings of the Australian Physiological and Pharmacological Society, Brisbane Queensland 27 September - 1 October 1998, Aust Physiological and Pharmacological Society, Vic Australia, p. 74P.

Cox, S., Shaw, J.M., Jenkin, G., 1998, The development of antral follicles in fetal mouse ovaries grafted into adult recipients is influenced by exogenous gonadotrophins and the recipients own ovaries, Australian Society for Reproductive Biology: Program and Miniposters, Perth WA 23-26 August 1998, University of Western Australia, Perth WA Australia, p. 16.

Cox, S., Shaw, J.M., Jenkin, G., 1998, The development of antral follicles in fetal mouse ovaries grafted into adult recipients is influenced by exogenous gonadotrophins and the recipients own ovaries, Australian Society for Reproductive Biology, 29th Annual Conference, Perth, Australia August 1998, Australian Society for Reproductive Biology, Canberra ACT Australia, p. 16.

Foulds, L.M., McFarlane, J.R., Jenkin, G., de Kretser, D.M., 1997, A novel activin binding protein in ovine allantoic fluid, Endocrine Society of Australia, Canberra, 28Sept-20 Oct, Endocrine Society of Australia, Australia, p. 53.

Foulds, L.M., McFarlane, J.R., Jenkin, G., de Kretser, D.M., 1997, A novel activin binding protein is present in ovine allantoic fluid, The Endocrine Society of Australia - Proceedings, 28/9-2/10/1997 Canberra, Endocrine Society of Australia, Prahran, p. 53.

Shaw, J.M., Jenkin, G., Schneider-Kolsky, M., 1997, Correlation between angiogenic growth factor expression and ovarian graft establishment in mice, The FSA XVI Annual Scientific Mtg Abstract Book, Adelaide 2 Dec 1997, FSA, Adelaide SA Australia, pp. 128-129.

Cox, S., Shaw, J.M., Jenkin, G., 1997, Cryopreservation of mouse fetal ovarian tissue, Human Reproduction, Edinburgh UK, 22-25 June, Oxford University Press, UK, pp. 4-5.

Cox, S., Shaw, J.M., Jenkin, G., 1997, Cryopreservation of mouse fetal tissue, Human Reproduction Abstract Book 1, Edinburgh, UK, 22 June 1997, Oxford Uni Press, Oxford UK, pp. 4-5.

de Kretser, D.M., McFarlane, J.R., Foulds, L.M., O'Connor, A.E., Yohkaichiya, T., Loveland, K.L., Jenkin, G., 1997, Inhibin, Activin and Follistatin: Observations on their role in the physiology of pregnancy, Inhibin, Activin and Follistatin: Regulatory Functions in System and Cell Biology, Serono Symp S.A. Pub/Springer-Verlag New York, Norwell Massachusetts USA, pp. 85-95.

de Kretser, D.M., McFarlane, J.R., Foulds, L.M., O'Conner, A., Yohkaichiya, T., Loveland, K.L., Jenkin, G., 1997, Inhibin, Activin, and Follistatin : Observations on their role in the physiology of pregnancy, Inhibin, Activin, and Follistatin - Regulatory functions in system and cell biology, 9-10 November 1996, Tokushima Japan, Springer-Verlag, New York NY USA, pp. 85-95.

Jenkin, G., Cox, S., Schneider-Kolsky, M., Tomlinson, E., Shaw, J.M., 1997, Investigation of auto and xeno transplantation and cryopreservation procedures for fetal, newborn and adult ovarian tissue, International Meeting on Infertility and Assisted Reproductive Technology: From Research to Therapy, Sardinia, Italy June 1997, Uni. of Sassari, Italy, p. 177.

Jenkin, G., Cox, S., Schneider-Kolsky, M.E., Tomlinson, L., Shaw, J.M., 1997, Investigation of auto and xeno transplantation and cryopreservation procedures for fetal, newborn and adult ovarian tissue, International Meeting on Infertility and Assisted Reproductive Technology - From Research to therapy - Abstracts Book, Porto Cerro Italy 11-14 June, Univ of Sassari, Cicily, Italy, p. 177.

Leung, S.T., Borwick, S.C., Thornton, S., Young, I.R., Jenkin, G., Wathes, D.C., 1997, Oestradiol receptors do not show a major up-regulation during labour in either sheep or women, Journal of Reproduction and Fertility, York UK, July 1997, Journal of Reproduction and Fertility, Cambridge UK, p. 45.

Miller, S., Jenkin, G., Walker, D.M., 1997, Physiological evidence for the presence of arteriovenous anastomoses in the uterine circulation of late pregnant sheep, Fetal and Neonatal Physiological Society, St Margherita Ligure Genoa Italy,15-18 June 1997, Fetal and Neonatal Physiological Society, Genoa Italy, p. 69.

Miller, S., Jenkin, G., Walker, D.M., 1997, Physiological evidence for the presence of arteriovenous anastomoses in the uterine circulation of late-pregnant ewes, Fetal & Neonatal Physiology Symposium/IUPS Congress Abstract Handbook, Cambridge UK, 25-29 June 1997, R & W Publications, Cambridge UK, p. 97.

Miller, S., Jenkin, G., Walker, D.M., 1997, The effects of nitric oxide inhibition of the uterine vasculature of the late-pregnant ewe, Fetal and Neonatal Physiological Society, Santa Margherito, Genoa, Italy, 15-18 June, Fetal and Neonatal Physiological Society, Italy, p. 9.

Cox, S., Shaw, J.M., Jenkin, G., 1997, Transplantation of postnatal and adult ovaries to adult female recipients in the mouse, J Reprod. Fertil, York, UK, July 1997, Journals of Reproduction & Fertility Ltd, UK, p. 66.

Cox, S., Shaw, J.M., Jenkin, G., 1997, Transplantation of postnatal and adult ovaries to female recipients in the mouse, Society for the Study of Fertility, British Fertility Society & British Andrology Society, Joint Meeting, York UK, July 1997, Journals of Reproduction and Fertility, Cambridge UK, p. 66.

Other

Jenkin, G., 1998, Obituary - Geoffrey Donald Thorburn AO FAA 1930-1996, Proceedings of the Australian Physiological and Pharmacological Society, Aust Physiological and Pharmacological Society, Melbourne Vic Australia.

Jenkin, G., Challis, J.R., Robinson, J., 1997, Obituary - Professor Geoffrey Donald Thorburn AO FAA, Obituary published in refereed journal "Reproduction, Fertility and Development".

Jenkin, G., 1997, Obituary: Professor Geoffrey Donald Thorburn, AO, FAA 1930-1996, Published in ANZCCART News.

Jenkin, G., 1997, Obituary: Professor Geoffrey Donald Thorburn, AO, FAA 1930-1996, Obituary published in the Endocrine Society of Australia Newsletter.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Lumbar intervertebral disc regeneration using mesenchymal progenitor cells (MPCs).

Supervisors:

Jenkin, G (Main), Rosenfeld, J (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Neonatal neurodevelopment after antioxidant with melatonin during late-pregnancy in an ovine model of intrauterine growth restriction.

Supervisors:

Jenkin, G (Main), Miller, S (Associate), Wallace, E (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Protecting the newborn brain following asphyxia at birth.

Supervisors:

Jenkin, G (Joint-co), Miller, S (Joint).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Therapies to reduce brain injury associated with birth asphyxia.

Supervisors:

Miller, S (Main), Jenkin, G (Associate), Wong, F (Associate).

Completed Supervision

Student:

Cleary, M.

Program of Study:

EVALUATION OF STRATEGIES FOR THE COLLECTION, CRYOPRESERVATION AND IN-VITRO MATURATION OF COMMON WOMBAT (VOMBATUS URSINUS) OVARIAN TISSUE. (PHD) 2004.

Supervisors:

Shaw, J (Main), Jenkin, G (Associate), Trounson, A (Associate).

Student:

Goldschlager, T.

Program of Study:

The role of progenitor stem cells in promoting cervical interbody fusion. (PHD) 2010.

Supervisors:

Jenkin, G (Joint-Co), Rosenfeld, J (Joint).

Student:

Gordon, C.

Program of Study:

CHARACTERISATION OF MOUSE AND HUMAN ermap/ERMAP GENES. (PHD) 2005.

Supervisors:

Perkins, A (Main), Jenkin, G (Associate).

Student:

Grigsby, P.

Program of Study:

DEVELOPMENT OF NEW STRATEGIES FOR THE INHIBITION OF PREMATURE LABOUR. (PHD) 2002.

Supervisors:

Jenkin, G (Main), Hirst, J (Joint).

Student:

Lewis, H.

Program of Study:

Cystic fibrosis: probing the link between CFTR mutation and CF lung phenotype, and the use of stem cells as a potential treatment. (PHD) 2008.

Supervisors:

Jenkin, G (Main), Wilson, J (Associate).

Student:

Milton, P.

Program of Study:

Mesenchymal stem cells as a therapeutic agent in models of pulmonary inflammation and fibrosis. (PHD) 2009.

Supervisors:

Jenkin, G (Main), Dickinson, H (Associate), Lim, R (Associate).

Student:

Murphy, S.

Program of Study:

Placental stem cells as a treatment for lung disease. (PHD) 2011.

Supervisors:

Jenkin, G (Main), Lim, R (Associate), Wallace, E (Associate).

Student:

Rose, I.

Program of Study:

Effects of activin on the structure and function of the developing chick brain. (Masters) 2003.

Supervisors:

Jenkin, G (Main).

Student:

Schneider-Kolsky, M.

Program of Study:

ACTIVIN A IN LATE PREGNANCY AND PARTURITION. (PHD) 2001.

Supervisors:

Wallace, E (Main), Jenkin, G (Joint).

Student:

Snow, M.

Program of Study:

OVARIAN XENOGRAFTING FOR THE CONSERVATION OF ENDANGERED SPECIES. (PHD) 2003.

Supervisors:

Jenkin, G (Main), Cox, S (Associate), Shaw, J (Associate).

Student:

Supramaniam, V.

Program of Study:

Activin A and fetal growth restriction. (PHD) 2005.

Supervisors:

Jenkin, G (Joint-Co), Miller, S (Joint).

Student:

Tong, S.

Program of Study:

INVESTIGATION OF NOVEL ENDOCRINE MARKERS OF EARLY PREGNANCY AND LATER PREGNANCY HEALTH. (PHD) 2004.

Supervisors:

Wallace, E (Main), Jenkin, G (Associate).