Prof Stuart Hooper - Researcher Profile

Biography

Professor Stuart Hooper is one of four Deputy Directors of the Ritchie Centre. Professor Hooper is an NHMRC Principal Research Fellow.

His research group within the Fetal, Neonatal & Child Health group of the Ritchie Centre aims to understand the physiology of fetal and neonatal lung development and the factors that regulate the transition to air-breathing at birth. By understanding these changes, it will become possible to moderate the impact of pre-term birth and other problems such as congenital diaphragmatic hernia, where the abdominal contents move into the chest cavity during fetal life.

All babies when born have to make the transition from the fluid-filled environment of the mother’s womb for an air-filled one after birth. Their lungs and heart have to start working differently the minute they are born. Professor Hooper’s research is intended to make the transition easier for babies with difficulties, most commonly pre-term babies. Professor Hooper uses synchrotron technology to image gases within tissues such as the lung.

Professor Hooper completed a BSc with Honours and a PhD in Reproductive Endocrinology at Monash University. He conducted post-doctoral research in fetal development at Monash University and the University of Western Ontario in Canada.

Professor Hooper has published 132 research and review scientific articles. He is currently President of the Perinatal Society of Australia and New Zealand and received a large NHMRC Program Grant ($8.5M) which started in 2011.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: Monash University

Year awarded: 2005

Publications

Book Chapters

Harding, R., Hooper, S.B., 2011, Physiologic mechanisms of normal and altered lung growth before and after birth, in Fetal and Neonatal Physiology, eds R.A. Polin, W.W. Fox and SH Abman, Saunders, USA, pp. 885-895.

Harding, R., Hooper, S.B., 2009, Lung growth and maturation, in Fetal Medicine: Basic Science and Clinical Practice, eds CH Rodeck & MJ Whittle, Churchill Livingstone, USA, pp. 133-146.

Harding, R., Hooper, S.B., Albuquerque, C.A., 2006, Fetal Breathing, in Encyclopedia of Respiratory Medicine, eds Geoffrey J Laurent and Steven D Shapiro, Elservier Ltd, Amsterdam Netherlands, pp. 242-246.

Hooper, S.B., Harding, R., 2006, Fetal Lung Liquid, in Encyclopedia of Respiratory Medicine, eds Geoffrey J. Laurent and Steven D. Shapiro, Elsevier Ltd, Amsterdam Netherlands, pp. 246-250.

Harding, R., Hooper, S.B., Wallace, M.J., 2006, Lung development, in Encyclopedia of Respiratory Medicine, eds Geoffrey J Laurent and Steven D Shapiro, Elsevier Ltd, Amsterdam Netherlands, pp. 613-619.

Hooper, S.B., Wallace, M.J., 2004, Physical, Endocrine and Growth Factors in Lung Development, in The Lung, eds R Harding, K Pinkerton & C Plopper, Elsevier Ltd, USA, pp. 131-148.

Harding, R., Hooper, S.B., 2004, Physiologic mechanisms of normal and altered lung growth, in Fetal and Neonatal Physiology, eds RA Polin, WW Fox & SH Abman, Elsevier, USA, pp. 802-811.

Hooper, S.B., Harding, R., 2004, Pulmonary transition at birth, in The Lung: Development, Aging and the Environment, eds Richard Harding, Kent E Pinkerton and Charles G Plopper, Elsevier Academic Press, USA, pp. 201-211.

Hooper, S.B., Harding, R., 2001, Respiratory System, in Fetal Growth and Development, eds Richard Harding, Alan D Bocking, Cambridge University Press, Cambridge United Kingdom, pp. 114-136.

Harding, R., Hooper, S.B., 1999, Lung development and maturation, in Fetal Medicine: Basic Science and Clinical Practice, eds -, Churchill Livingstone, London UK, pp. 181-196.

Hooper, S.B., Young, I.R., 1998, Endocrine maturation of the fetus, in Endocrinology of Pregnancy, Humana Press, Totowa New Jersey USA, pp. 353-385.

Journal Articles

Fouras, A., Allison, B.J., Kitchen, M.J., Dubsky, S.E., Nguyen, J.T., Hourigan, K., Siu, K.K.W., Lewis, R., Wallace, M.J., Hooper, S.B., 2012, Altered lung motion is a sensitive indicator of regional lung disease, Annals Of Biomedical Engineering [P], vol 40, issue 5, Springer, New York NY USA, pp. 1160-1169.

van Vonderen, J.J., Kleijn, T.A., Schilleman, K., Walther, F.J., Hooper, S.B., Te Pas, A.B., 2012, Compressive force applied to a manikin's head during mask ventilation, Archives of Disease in Childhood: Fetal and Neonatal Edition [P], vol 97, issue 4, B M J Group, United Kingdom, pp. F254-F258.

Crossley, K.J., Allison, B.J., Polglase, G., Morley, C.J., Harding, R., Davis, P.G., Moss, T.J.M., Hooper, S.B., 2012, Effects of caffeine on renal and pulmonary function in preterm newborn lambs, Pediatric Research [P], vol 72, issue 1, Nature Publishing Group, United States, pp. 19-25.

van Vonderen, J.J., Siew, M.L., Hooper, S.B., de Boer, M.A., Walther, F.J., Te Pas, A.B., 2012, Effects of naloxone on the breathing pattern of a newborn exposed to maternal opiates, Acta Paediatrica [P], vol 101, issue 7, Wiley-Blackwell Publishing Ltd, United Kingdom, pp. e309-e312.

Thurgood, J.B., Hooper, S.B., Siew, M.L., Wallace, M.J., Dubsky, S.E., Kitchen, M.J., Jamison, R.A., Carnibella, R., Fouras, A., 2012, Functional Lung Imaging during HFV in Preterm Rabbits, PLoS ONE [P], vol 7, issue 10, Public Library Science, San Francisco CA USA, pp. 1-7.

Jamison, R.A., Armitage, J., Carberry, J.J., Kitchen, M.J., Hooper, S.B., Fouras, A., 2012, Functional imaging to understand biomechanics: a critical tool for the study of biology, pathology and the development of pharmacological solutions, Current Pharmaceutical Biotechnology [P], vol 13, issue 11, Bentham Science, SharJah United Arab Emirates, pp. 2128-2140.

Bach, K.P., Kuschel, C., Hooper, S.B., Bertram, J., McKnight, S., Peachey, S.E., Zahra, V.A., Flecknoe, S.J., Oliver, M.H., Wallace, M.J., Bloomfield, F.H., 2012, High bias gas flows increase lung injury in the ventilated preterm lamb, PLoS ONE [P], vol 7, issue 10 (Art. ID: e47044), Public Library Of Science, United States, pp. 1-9.

Hodges, R., Jenkin, G., Hooper, S., Allison, B., Lim, R., Dickinson, H., Miller, S., Vosdoganes, P., Wallace, E., 2012, Human amnion epithelial cells reduce ventilation-induced preterm lung injury in fetal sheep , American Journal Of Obstetrics And Gynecology [P], vol 206, issue 5 (Art. No.: 448), Mosby Inc., United States, pp. 8-15.

Polglase, G., Nitsos, I., Baburamani, A., Crossley, K., Slater, M., Gill, A., Allison, B., Moss, T., Pillow, J., Hooper, S., Kluckow, M., 2012, Inflammation in utero exacerbates ventilation-induced brain injury in preterm lambs, Journal of Applied Physiology [E], vol 112, issue 3, American Physiological Society, United States, pp. 481-489.

Polglase, G., Miller, S.L., Barton, S., Baburamani, A.A., Wong, F.Y., Aridas, J., Gill, A.W., Moss, T.J.M., Tolcos, M., Kluckow, M., Hooper, S.B., 2012, Initiation of resuscitation with high tidal volumes causes cerebral hemodynamic disturbance, brain inflammation and injury in preterm lambs, PLoS ONE [P], vol 7, issue 6 (Art. No: e39535), Public Library of Science, United States, pp. 1-8.

Wheeler, K., Morley, C.J., Hooper, S.B., Davis, P.G., 2012, Lower back-up rates improve ventilator triggering during assist-control ventilation: a randomized crossover trial, Journal of Perinatology [P], vol 32, issue 2, Nature Publishing Group, United Kingdom, pp. 111-116.

Westover, A., Hooper, S., Wallace, M., Moss, T., 2012, Prostaglandins mediate the fetal pulmonary response to intrauterine inflammation, American Journal Of Physiology-Lung Cellular And Molecular Physiology [P], vol 302, issue 7, American Physiological Society, United States, pp. L664-L678.

Schmolzer, G., Morley, C., Wong, C., Dawson, J., Kamlin, C., Donath, S., Hooper, S., Davis, P., 2012, Respiratory function monitor guidance of mask ventilation in the delivery room: a feasibility study, Journal Of Pediatrics [P], vol 160, issue 3 (Art. No: e2), Mosby, Inc., United States, pp. 377-381.

Dubsky, S.E., Hooper, S.B., Siu, K.K.W., Fouras, A., 2012, Synchrotron-based dynamic computed tomography of tissue motion for regional lung function measurement, Journal Of The Royal Society Interface [P], vol 9, issue 74, Royal Society, London London UK, pp. 2213-2224.

Polglase, G., Hooper, S., Kluckow, M., Gill, A., Harding, R., Moss, T., 2012, The cardiopulmonary haemodynamic transition at birth is not different between male and female preterm lambs, Reproduction, Fertility and Development [P], vol 24, issue 3, C S I R O Publishing, Australia, pp. 510-516.

Sobotka, K., Hooper, S., Allison, B., Te Pas, A., Davis, P., Morley, C.J., Moss, T., 2011, An initial sustained inflation improves the respiratory and cardiovascular transition at birth in preterm lambs, Pediatric Research [P], vol 70, issue 1, Lippincott Williams & Wilkins, United States, pp. 56-60.

Polglase, G., Kluckow, M., Gill, A., Allison, B., Moss, T., Dalton, R., Pillow, J., Nitsos, I., Andersen, C., Hooper, S., 2011, Cardiopulmonary haemodynamics in lambs during induced capillary leakage immediately after preterm birth, Clinical And Experimental Pharmacology And Physiology [P], vol 38, issue 4, Wiley-Blackwell Publishing Asia, Australia, pp. 222-228.

Hooper, S.B., Kitchen, M.J., Fouras, A., Wallace, M.J., Dubsky, S., Siu, K.K.W., Siew, M.L., Yagi, N., Uesugi, K., Lewis, R.A., 2011, Combined lung imaging and respiratory physiology research at SPring-8, Synchrotron Radiation News [P], vol 24, issue 2, Taylor & Francis Ltd, UK, pp. 19-23.

Galinsky, R., Moss, T., Gubhaju, L., Hooper, S., Black, M., Polglase, G., 2011, Effect of intra-amniotic lipopolysaccharide on nephron number in preterm fetal sheep, American Journal Of Physiology-Renal Physiology [P], vol 301, issue 2, American Physiological Society, United States, pp. F280-F285.

Brew, N., Hooper, S., Allison, B., Wallace, M., Harding, R., 2011, Injury and repair in the very immature lung following brief mechanical ventilation, American Journal Of Physiology-Lung Cellular And Molecular Physiology [P], vol 301, issue 6, American Physiological Society, USA, pp. L917-L926.

Beltran, M., Paganin, D., Siu, K., Fouras, A., Hooper, S., Reser, D., Kitchen, M., 2011, Interface-specific x-ray phase retrieval tomography of complex biological organs, Physics in Medicine and Biology [P], vol 56, issue 23, Institute of Physics Publishing Ltd, UK, pp. 7353-7369.

Kitchen, M., Paganin, D., Uesugi, K., Allison, B., Lewis, R., Hooper, S., Pavlov, K., 2011, Phase contrast image segmentation using a Laue analyser crystal, Physics in Medicine and Biology [P], vol 56, issue 3, Institute of Physics Publishing Ltd, UK, pp. 515-534.

Siew, M., Te Pas, A., Wallace, M., Kitchen, M., Islam, M., Lewis, R., Fouras, A., Morley, C., Davis, P., Yagi, N., Uesugi, K., Hooper, S., 2011, Surfactant increases the uniformity of lung aeration at birth in ventilated preterm rabbits, Pediatric Research [P], vol 70, issue 1, Lippincott Williams & Wilkins, United States, pp. 50-55.

Andersen, C., Pillow, J., Gill, A., Allison, B., Moss, T., Hooper, S., Nitsos, I., Kluckow, M., Polglase, G., 2011, The cerebral critical oxygen threshold of ventilated preterm lambs and the influence of antenatal inflammation, Journal of Applied Physiology Respiratory Environmental and Exercise Physiology [P], vol 111, issue 3, American Physiological Society, United States, pp. 775-781.

McDougall, A., Hooper, S., Zahra, V., Sozo, F., Lo, C., Cole, T., Doran, T., Wallace, M., 2011, The oncogene Trop2 regulates fetal lung cell proliferation, American Journal Of Physiology-Lung Cellular And Molecular Physiology [P], vol 301, issue 4, American Physiological Society, United States, pp. L478-L489.

Bird, A.D., Flecknoe, S.J., Tan, K.H., Olsson, P.F., Antony, N., Mantamadiotis, T., Mollard, R.A., Hooper, S.B., Cole, T.J., 2011, cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development, PLoS ONE [P], vol 6, issue 3 (Art. No: e17843), Public Library of Science, USA, pp. 1-15.

Kitchen, M., Habib, A., Fouras, A., Dubsky, S., Lewis, R., Wallace, M., Hooper, S., 2010, A new design for high stability pressure-controlled ventilation for small animal lung imaging, Journal of Instrumentation [P], vol 5, issue 2, Institute of Physics Publishing Ltd, Bristol England, pp. 1-12.

Schmolzer, G.M., Hooper, S.B., Crossley, K.J., Allison, B.J., Morley, C.J., Davis, P.G., 2010, Assessment of gas flow waves for endotracheal tube placement in an ovine model of neonatal resuscitation, Resuscitation [P], vol 81, issue 6, Elsevier Ireland Ltd, Ireland, pp. 737-741.

Dawson, J., Kamlin, C.O., Wong, C.H., te Pas, A.B., Vento, M., Cole, T.J., Donath, S., Hooper, S.B., Davis, P.G., Morley, C.J., 2010, Changes in heart rate in the first minutes after birth, Archives of Disease in Childhood: Fetal and Neonatal..., vol 95, issue 3, BMJ Group, UK, pp. F177-F181.

Hooper, S.B., te Pas, A.B., Lewis, R., Morley, C.J., 2010, Establishing functional residual capacity at birth, NeoReviews [P], vol 11, issue 9, American Academy of Pediatrics, USA, pp. 474-483.

Polglase, G., Hooper, S.B., Gill, A.W., Allison, B.J., Crossley, K.J., Moss, T.J.M., Nitsos, I., Pillow, J.J., Kluckow, M., 2010, Intrauterine inflammation causes pulmonary hypertension and cardiovascular sequelae in preterm lambs, Journal Of Applied Physiology [P], vol 108, issue 6, American Physiological Society, USA, pp. 1757-1765.

Filby, C., Hooper, S., Wallace, M., 2010, Partial pulmonary embolization disrupts alveolarization in fetal sheep, Respiratory Research [P], vol 11, issue 42, BioMed Central Ltd, United Kingdom, pp. 1-15.

Allison, B.J., Crossley, K.J., Flecknoe, S.J., Morley, C.J., Polglase, G.R., Hooper, S.B., 2010, Pulmonary hemodynamic responses to in utero ventilation in very immature fetal sheep, Respiratory Research [P], vol 11, issue 1 (Art. No. 111), BioMed Central Ltd, UK, pp. 1-11.

Allison, B.J., Crossley, K.J., Flecknoe, S.J., Davis, P.G., Morley, C.J., Hooper, S.B., 2010, Ventilation and oxygen: Dose-related effects of oxygen on ventilation-induced lung injury, Pediatric Research [P], vol 67, issue 3, Lippincott Williams & Wilkins, USA, pp. 238-243.

Kitchen, M., Paganin, D., Uesugi, K., Allison, B., Lewis, R., Hooper, S., Pavlov, K., 2010, X-ray phase, absorption and scatter retrieval using two or more phase contrast images, Optics Express [P], vol 18, issue 19, Optical Society of America, Washington DC USA, pp. 19994-20012.

Crossley, K.J., Morley, C.J., Allison, B.J., Davis, P.G., Polglase, G.R., Wallace, M.J., Zahra, V.A., Hooper, S.B., 2009, Antenatal corticosteroids increase fetal, but not postnatal, pulmonary blood flow in sheep, Pediatric Research [P], vol 66, issue 3, Lippincott Williams & Wilkins, USA, pp. 283-288.

Polglase, G.R., Hooper, S.B., Gill, A.W., Allison, B.J., McLean, C.J., Nitsos, I., Pillow, J.J., Kluckow, M., 2009, Cardiovascular and pulmonary consequences of airway recruitment in preterm lambs, Journal of Applied Physiology, vol 106, issue 4, American Physiological Society, USA, pp. 1347-1355.

Crossley, K.J., Allison, B.J., Polglase, G.R., Morley, C.J., Davis, P.G., Hooper, S.B., 2009, Dynamic changes in the direction of blood flow through the ductus arteriosus at birth, Journal Of Physiology-London [P], vol 587, issue Pt. 19, Wiley-Blackwell Publishing Ltd., UK, pp. 4695-4704.

Wallace, M.J., Probyn, M.E., Zahra, V.A., Crossley, K.J., Cole, T.J., Davis, P.G., Morley, C.J., Hooper, S.B., 2009, Early biomarkers and potential mediators of ventilation-induced lung injury in very preterm lambs, Respiratory Research, vol 10, issue 19, BioMed Central Ltd, UK, pp. 1-15.

Te Pas, A.B., Siew, M.L., Wallace, M.J., Kitchen, M.J., Fouras, A., Lewis, R., Yagi, N., Uesugi, K., Donath, S., Davis, P.G., Morley, C.J., Hooper, S.B., 2009, Effect of sustained inflation length on establishing functional residual capacity at birth in ventilated premature rabbits, Pediatric Research [P], vol 66, issue 3, Lippincott Williams & Wilkins, USA, pp. 295-300.

Te Pas, A.B., Siew, M.L., Wallace, M.J., Kitchen, M.J., Fouras, A., Lewis, R.A., Yagi, N., Uesugi, K., Donath, S., Davis, P.G., Morley, C.J., Hooper, S.B., 2009, Establishing functional residual capacity at birth: The effect of sustained inflation and positive end-expiratory pressure in a preterm rabbit model, Pediatric Research [P], vol 65, issue 5, Lippincott Williams & Wilkins, USA, pp. 537-541.

Hooper, S.B., Kitchen, M.J., Siew, M.L., Lewis, R.A., Fouras, A., te Pas, A.B., Siu, K.K.W., Yagi, N., Uesugi, K., Wallace, M.J., 2009, Imaging lung aeration and lung liquid clearance at birth using phase contrast x-ray imaging, Clinical and Experimental Pharmacology & Physiology, vol 36, issue 1, Wiley-Blackwell Publishing Asia, Australia, pp. 117-125.

Siew, M.L., Wallace, M.J., Kitchen, M.J., Lewis, R.A., Fouras, A., te Pas, A.B., Yagi, N., Uesugi, K., Siu, K.K.W., Hooper, S.B., 2009, Inspiration regulates the rate and temporal pattern of lung liquid clearance and lung aeration at birth, Journal of Applied Physiology, vol 106, issue 6, American Physiological Society, USA, pp. 1888-1895.

O'Reilly, M., Hooper, S.B., Allison, B.J., Flecknoe, S.J., Snibson, K., Harding, R., Sozo, F., 2009, Persistent bronchiolar remodeling following brief ventilation of the very immature ovine lung, American Journal Of Physiology-Lung Cellular And M..., vol 297, issue 5, American Physiological Society, USA, pp. L992-L1001.

Siew, M.L., te Pas, A.B., Wallace, M.J., Kitchen, M.J., Lewis, R.A., Fouras, A., Morley, C.J., Davis, P.G., Yagi, N., Uesugi, K., Hooper, S.B., 2009, Positive end-expiratory pressure enhances development of a functional residual capacity in preterm rabbits ventilated from birth, Journal of Applied Physiology, vol 106, issue 5, American Physiological Society, USA, pp. 1487-1493.

Fouras, A., Kitchen, M.J., Dubsky, S.E., Lewis, R., Hooper, S.B., Hourigan, K., 2009, The past, present, and future of x-ray technology for in vivo imaging of function and form, Journal Of Applied Physics [P], vol 105, issue 100, American Institute of Physics, United States, pp. 102009-1-102009-14.

Polglase, G.R., Moss, T., Nitsos, I., Allison, B.J., Pillow, J.J., Hooper, S.B., 2008, Differential effect of recruitment maneuvres on pulmonary blood flow and oxygenation during HFOV in preterm lambs, Journal of Applied Physiology, vol 105, issue 2, American Physiological Society, United States, pp. 603-610.

Kitchen, M.J., Lewis, R., Morgan, M.J., Wallace, M.J., Siew, M.L., Siu, K.K.W., Habib, A., Fouras, A., Yagi, N., Uesugi, K., Hooper, S.B., 2008, Dynamic measures of regional lung air volume using phase contrast x-ray imaging, Physics in Medicine and Biology, vol 53, issue 21, Institute of Physics Publishing, UK, pp. 6065-6077.

Te Pas, A., Davis, P.G., Hooper, S.B., Morley, C.J., 2008, From liquid to air: Breathing after birth, The Journal of Pediatrics, vol 152, issue 5, Mosby, Inc., United States, pp. 607-611.

Kitchen, M.J., Pavlov, K.M., Hooper, S.B., Vine, D.J., Siu, K.K.W., Wallace, M.J., Siew, M.L., Yagi, N., Uesugi, K., Lewis, R., 2008, Simultaneous acquisition of dual analyser-based phase contrast x-ray images for small animal imaging, European Journal of Radiology, vol 68, Elsevier, Ireland, pp. 49-53.

Allison, B.J., Crossley, K.J., Flecknoe, S.J., Davis, P.G., Morley, C.J., Harding, R., Hooper, S.B., 2008, Ventilation of the very immature lung in utero induces injury and BPD-like changes in lung structure in fetal sheep, Pediatric Research, vol 64, issue 4, Lippincott Williams & Wilkins, United States, pp. 387-392.

Crossley, K.J., Morley, C.J., Allison, B.J., Polglase, G.R., Dargaville, P.A., Harding, R., Hooper, S.B., 2007, Blood gases and pulmonary blood flow during resuscitation of very preterm lambs treated with antenatal betamethasone and/or curosurf: Effect of positive end-expiratory pressure, Pediatric Reseaarch, vol 62, issue 1, Int Pediatric Research Foundation Inc, Baltimore MD USA, pp. 37-42.

Faggian, J., Fosang, A.J., Zieba, M., Wallace, M.J., Hooper, S.B., 2007, Changes in versican and chondroitin sulfate proteoglycans during structural development of the lung, American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol 293, issue 2, Americal Physiological Society, Bethesda MD USA, pp. R784-R792.

Olsson, F.P., Denham, M., Cole, T.J., Hooper, S.B., Mollard, R.A., 2007, Deriving respiratory cell types from stem cells, Current Stem Cell Research & Therapy, vol 2, issue 3, Bentham Science Publishers Ltd, The Netherlands, pp. 197-208.

Bird, A.D., Tan, K.H., Olsson, F.P., Zieba, M., Flecknoe, S.J., Liddicoat, D., Mollard, R.A., Hooper, S.B., Cole, T.J., 2007, Identification of glucocorticoid-regulated genes that control cell proliferation during murine respiratory development, Journal of Physiology-London, vol 585, issue 1, Blackwell Publishing, Oxford England UK, pp. 187-201.

Hooper, S.B., Kitchen, M.J., Wallace, M.J., Yagi, N., Uesugi, K., Morgan, M.J., Hall, C.J., Siu, K.K.W., Williams, I.M., Siew, M.L., Irvine, S.C., Pavlov, K.M., Lewis, R., 2007, Imaging lung aeration and lung liquid clearance at birth, The FASEB Journal, vol 21, issue 12, Federation of American Society of Experimental Biologists, USA, pp. 3329-3337.

Flecknoe, S.J., Crossley, K.J., Zuccala, G.M., Searle, J.E., Allison, B.J., Wallace, M.J., Hooper, S.B., 2007, Increased lung expansion alters lung growth but not alveolar epithelial cell differentiation in newborn lambs, American Journal of Physiology-Lung Cellular and Molecular Physiology, vol 292, issue 2, American Physiological Society, Bethesda USA, pp. L454-L461.

Sozo, F., Hooper, S.B., Wallace, M.J., 2007, Thrombospondin-1 expression and localization in the developing ovine lung, Journal of Physiology-London, vol 584, issue Pt 2, Blackwell Publishing, Oxford England UK, pp. 625-635.

Sozo, F., Wallace, M.J., Hanna, M., Flecknoe, S.J., Cock, M.L., Maritz, G., Harding, R., Hooper, S.B., 2006, Alveolar epithelial cell differentiation and surfactant protein expression after mild preterm birth in sheep, Pediatric Research, vol 59, issue 1, Int. Pediartric Research Foundation, Inc., Baltimore USA, pp. 151-156.

Suzuki, K., Hooper, S.B., Wallace, M.J., Probyn, M.E., Harding, R., 2006, Effects of antenatal corticosteroid treatment on pulmonary ventilation and circulation in neonatal lambs with hypoplastic lungs, Pediatric Pulmonology, vol 41, issue 9, John Wiley & Sons, Inc, Hoboken USA, pp. 844-854.

Sozo, F., Wallace, M.J., Zahra, V.A., Filby, C.E., Hooper, S.B., 2006, Gene expression profiling during increased fetal lung expansion identifies genes likely to regulate development of the distal airways, Physiological Genomics, vol 24, issue 2, American Physiological Society, Bethesda USA, pp. 105-113.

Polglase, G.R., Wallace, M.J., Morgan, D.L., Hooper, S.B., 2006, Increases in lung expansion alter pulmonary hemodynamics in fetal sheep, Journal of Applied Physiology, vol 101, issue 1, American Physiology Society, Bethesda USA, pp. 273-282.

Polglase, G.R., Hooper, S.B., 2006, Role of intra-luminal pressure in regulating PBF in the fetus and after birth, Current Pediatric Reviews, vol 2, issue 4, Benthan Science Publishers Ltd, Netherlands, pp. 287-299.

Wallace, M.J., Thiel, A.M., Lines, A.M., Polglase, G., Sozo, F., Hooper, S.B., 2006, Role of platelet-derived growth factor-B, vascular endothelial growth factor, insulin-like growth factor-II, mitogen-activated protein kinase and transforming growth factor-beta1 in expansion-induced lung growth in fetal sheep, Reproduction, Fertility and Development, vol 18, issue 6, CSIRO, Australia, pp. 655-665.

Hooper, S.B., Wallace, M.J., 2006, Role of the physicochemical environment in lung development, Clinical and Experimental Pharmacology and Physiology, vol 33, issue 3, Blackwell Publishing Asia, Australia, pp. 273-279.

Filby, C.E., Hooper, S.B., Sozo, F., Zahra, V.A., Flecknoe, S.J., Wallace, M.J., 2006, VDUP1: A potential mediator of expansion-induced lung growth and epithelial cell differentiation in the ovine fetus, American Journal of Physiology - Lung Cellular and Molecular Physiology, vol 290, issue 2, American Physiological Society, USA, pp. L250-L258.

Lewis, R.A., Yagi, N., Kitchen, M.J., Morgan, M.J., Paganin, D., Siu, K.K.W., Pavlov, K.M., Williams, I.M., Uesugi, K., Wallace, M.J., Hall, C.J., Whitley, J., Hooper, S.B., 2005, Dynamic imaging of the lungs using X-ray phase contrast, Physics in Medicine and Biology, vol 50, issue 21, Institute of Physics Publishing, Bristol UK, pp. 5031-5040.

Suzuki, K., Hooper, S.B., Cock, M.L., Harding, R., 2005, Effect of lung hypoplasia on birth-related changes in the pulmonary circulation in sheep, Pediatric Research, vol 57, issue 4, Lippingcott Williams & Wilkins, USA, pp. 530-536.

Probyn, M.E., Hooper, S.B., Dargaville, P.A., McCallion, N., Harding, R., Morley, C.J., 2005, Effects of tidal volume and positive end-expiratory pressure during resuscitation of very premature lambs, Acta Paediatrica, vol 94, issue 12, Taylor & Francis Ltd, UK, pp. 1764-1770.

Kitchen, M.J., Lewis, R., Yagi, N., Uesugi, K., Paganin, D., Hooper, S.B., Adams, G., Jureczek, S., Singh, J., Christensen, C.R., Hufton, A., Hall, C., Cheung, K., Pavlov, K.M., 2005, Phase contrast X-ray imaging of mice and rabbit lungs: a comparative study, The British Journal of Radiology, vol 78, issue 935, The British Institute of Radiology, UK, pp. 1018-1027.

Polglase, G.R., Morley, C.J., Crossley, K.J., Dargaville, P.A., Harding, R., Morgan, D.L., Hooper, S.B., 2005, Positive end-expiratory pressure differentially alters pulmonary hemodynamics and oxygenation in ventilated, very premature lambs, Journal of Applied Physiology, vol 99, issue 4, American Physiological Society, Bethesda USA, pp. 1453-1461.

Cock, M.L., Hanna, M., Sozo, F., Wallace, M.J., Yawno, T., Suzuki, K., Maritz, G.S., Hooper, S.B., Harding, R., 2005, Pulmonary function structure following mild preterm birth in lambs, Pediatric Pulmonology, vol 40, issue 4, John Wiley & Sons, Inc., USA, pp. 336-348.

Hooper, S.B., Harding, R., 2005, Role of aeration in the physiological adaptation of the lung to air-breathing at birth, Current Respiratory Medicine Reviews, vol 1, issue 2, Bentham Science Publishers Ltd, The Netherlands, pp. 185-195.

Cole, T.J., Solomon, N.M., Van Driel, R., Monk, J.A., Bird, D., Richardson, S.J., Dilley, R.J., Hooper, S.B., 2004, Altered epithelial cell proportions in the fetal lung of glucocorticoid receptor null mice, American Journal of Respiratory Cell and Molecular Biology, vol 30, issue 5, American Thoracic Society, New York USA, pp. 613-619.

Boland, R.E., Joyce, B.J., Wallace, M.J., Stanton, H., Fosang, A.J., Pierce, R.A., Harding, R., Hooper, S.B., 2004, Cortisol enhances structural maturation of the hypoplastic fetal lung in sheep, Journal of Physiology, vol 554, issue 2, Blackwell Publishing, Oxford UK, pp. 505-517.

Polglase, G.R., Wallace, M.J., Grant, D.A., Hooper, S.B., 2004, Influence of fetal breathing movements on pulmonary hemodynamics in fetal sheep, Pediatric Research, vol 56, issue 6, International Pediatric Research Foundation, Inc., Baltimore USA, pp. 932-938.

Probyn, M.E., Hooper, S.B., Dargaville, P.A., McCallion, N., Crossley, K.J., Harding, R., Morley, C.J., 2004, Positive end expiratory pressure during resuscitation of premature lambs rapidly improves blood gases without adversely affecting arterial pressure, Pediatric Research, vol 56, issue 2, International Pediatric Research Foundation, Inc., Baltimore USA, pp. 198-204.

Cock, M.L., Hooper, S.B., Wallace, M.J., Gagnon, R., Brace, R.A., Louey, S.C., Harding, R., 2004, Pulmonary elastin synthesis and deposition in developing and mature sheep: effects of intrauterine growth restriction, Experimental Lung Research, vol 30, issue 5, Taylor & Francis Inc., Philadelphia USA, pp. 405-418.

Flecknoe, S.J., Boland, R.E., Wallace, M.J., Harding, R., Hooper, S.B., 2004, Regulation of alveolar epithelial cell phenotypes in fetal sheep: roles of cortisol and lung expansion, American Journal of Physiology-Lung Cellular and Molecular Physiology, vol 287, issue 6, American Physiological Society, Bethesda USA, pp. 1207-1214.

Liu, H., Hooper, S.B., Armugan, A., Dawson, N.F., Ferraro, T., Jeyaseelan, K., Thiel, A.M., Koukoulas, I., Wintour, E.M., 2003, Aquarporin gene expression and regulation in the ovine fetal lung, Journal of Physiology - London, vol 551, issue 2, Cambridge University Press, New York USA, pp. 503-514.

Flecknoe, S.J., Wallace, M.J., Cock, M.L., Harding, R., Hooper, S.B., 2003, Changes in alveolar epithelial cell proportions during fetal and postnatal development in sheep, American Journal of Physiology, Lung Cellular and Molecular Physiology, vol 285, issue 3, American Physiological Society, Bethesda USA, pp. 664-670.

Joyce, B.J., Wallace, M.J., Pierce, R.A., Harding, R., Hooper, S.B., 2003, Sustained changes in lung expansion alter tropoelastin mRNA levels and elastin content in fetal sheep lungs, American Journal of Physiology - Lung Cellular and Molecular Physiology, vol 284, issue 4, American Physiological Society, Bethesda USA, pp. 643-649.

Flecknoe, S.J., Wallace, M.J., Harding, R., Hooper, S.B., 2002, Determination of alveolar epithelial cell phenotypes in fetal sheep: evidence for the involvement of basal lung expansion, Journal of Physiology, vol 542-1, Cambridge University Press, New York NY USA, pp. 245-253.

Joyce, B.J., Louey, S., Davey, M.G., Cock, M., Hooper, S.B., Harding, R., 2001, Compromised respiratory function in postnatal lambs after placental insufficiency and intrauterine growth restriction, Pediatric Research, vol 50, issue 5, INT Pediatric Research Foundation, Baltimore MD USA, pp. 641-649.

Cock, M., Albuquerque, C.A., Joyce, B.J., Hooper, S.B., Harding, R., 2001, Effects of intrauterine growth restriction on lung liquid dynamics and lung development in fetal sheep, American Journal of Obstetrics and Gynecology, vol 184, Mosby Inc, St Louis MO USA, pp. 209-216.

Jenkin, G., Ward, J.N.A., Hooper, S.B., O'Connor, A., de Kretser, D.M., Wallace, E.M., 2001, Feto-placental hypoxemia regulates the release of fetal activin A and prostaglandin E2, Endocrinology, vol 142, issue 2, Endocrine Society, Bethesda USA, pp. 963-966.

Lines, A.M., Gillett, A.M., Phillips, I.D., Wallace, M.J., Hooper, S.B., 2001, Re-expression of pulmonary surfactant proteins following tracheal obstruction in fetal sheep, Experimental Physiology, vol 86, issue 1, Cambridge University Press, New York NY USA, pp. 55-63.

Davey, M.G., Hooper, S.B., Cock, M., Harding, R., 2001, Stimulation of lung growth in fetuses with lung hypoplasia leads to altered postnatal lung structure in sheep, Pediatric Pulmonology, vol 32, issue 4, Wiley-Liss, New York NY USA, pp. 267-276.

Nardo, L., Maritz, G., Harding, R., Hooper, S.B., 2000, Changes in lung structure and cellular division induced by tracheal obstruction in fetal sheep, Experimental lung research, vol 26, Hemipshere publishing corporation, Bristol PA USA, pp. 105-119.

Probyn, M., Wallace, M., Hooper, S.B., 2000, Effect of increased lung expansion lung growth development near midgestation in fetal sheep, Pediatric Research, vol 47 issue 6, International Pediatric Research Foundation, Baltimore MD USA, pp. 806-812.

Harding, R., Tester, M., Moss, T.J., Davey, M.G., Louey, S., Joyce, B.J., Hooper, S.B., Maritz, G., 2000, Effects of intra-uterine growth restriction on the control of breathing and lung development after birth, Clinical & Experimental Pharmacology and Physiology, vol 27 issue 1, Blackwell Science Asia, Melbourne Vic Australia, pp. 114-119.

Flecknoe, S.J., Harding, R., Maritz, G., Hooper, S.B., 2000, Increased lung expansion alters the proportions of type I and type II alveolar epithelial cells in fetal sheep, American Journal of Physiology: Lung cell and molecular physiology, vol 278, American Physiology Society, Bethesda MD USA, pp. L1180-L1185.

Nardo, L., Young, I.R., Hooper, S.B., 2000, Influence of growth hormone on the lung growth response to tracheal obstruction in fetal sheep, American Journal of Physiology: Lung cell and molecular physiology, vol 278, American Physiology Society, Bethesda MD USA, pp. L453-L459.

Harding, R., Cock, M.L., Louey, S., Joyce, B.J., Davey, M.G., Albuquerque, C.A., Hooper, S.B., Maritz, G.S., 2000, The compromised intra-uterine environment: implications for futrue lung health, Clinical and Experimental Pharmacology and Physiology, vol 27 issue 12, Blackwell Science Asia, Melbourne Vic Australia, pp. 965-974.

Lines, A., Nardo, L., Phillips, I.D., Possmayer, F., Hooper, S.B., 1999, Alterations in lung expansion affect surfactant protein A, B, and C mRNA levels in fetal sheep, American Journal of Physiology, vol 276 issue 2, American Physiological Society, http://intl-ajplung.physiology.org, pp. 239L-245L.

Davey, M.G., Hooper, S.B., Tester, M., Johns, D.P., Harding, R., 1999, Respiratory function in lambs after "in utero" treatment of lung hypoplasia by tracheal obstruction, Journal of Applied Physiology, vol 87 issue 6, American Physiological Society, Bethesda MD USA, pp. 2296-2304.

Wlodek, M.E., Hooper, S.B., Thorburn, G.D., Tester, M., Harding, R., 1998, Effects of prostaglandin E2 on renal function and lung liquid dynamics in foetal sheep, Clinical and Experimental Pharmacology and Physiology, vol 25, Blackwell Science Asia, Carlton Vic Australia, pp. 805-812.

Hooper, S.B., 1998, Role of luminal volume changes in the increase in pulmonary blood flow at birth in sheep, Experimental Physiology, vol 83 (6), Cambridge University Press, Cambridge UK, pp. 833-842.

Nardo, L., Hooper, S.B., Harding, R., 1998, Stimulation of growth by tracheal obstruction in fetal sheep: relation to luminal pressure and lung liquid volume, Pediatric Research, vol 43 (2), American Pediatric Society, Baltimore USA, pp. 184-190.

Boland, R.E., Nardo, L., Hooper, S.B., 1997, Cortisol pretreatment enhances the lung growth response to tracheal obstruction in fetal sheep, American Journal of Physiology, vol 273, American Physiological Society, Bethesda MD USA, pp. L1126-L1131.

Stratford, L.L., Hooper, S.B., 1997, Effect of hypoxemia on tissue glycogen content and glycolytic enzyme activities in fetal sheep, American Journal of Physiology, vol 272, American Physiological Society, Bethesda MD USA, pp. R103-R110.

Lines, A., Hooper, S.B., Harding, R., 1997, Lung liquid production rates and volumes do not decrease before labour in healthy fetal sheep, Journal of Applied Physiology, vol 82, American Physiological Society, Bethesda MD USA, pp. 927-932.

Rees, S., Stringer, M., Just, Y., Hooper, S.B., Harding, R., 1997, The vulnerability of the fetal sheep brain to hypoxemia at mid gestation, Developmental Brain Research, vol 103, Elsevier, Amsterdam Netherlands, pp. 103-118.

Conference Proceedings

Fouras, A., Dubsky, S.E., Nguyen, J.T., Hourigan, K., Kitchen, M.J., Allison, B.J., Wallace, M.J., Siew, M.L., Siu, K.K.W., Lewis, R., Uesugi, K., Yagi, N., Hooper, S.B., 2009, In-vivo Synchrotron PIV for the masurement of airway motion, Proc. 8th International Symposium on Particle Image Velocimetry, 25-28 August, PIV09 Committee, Australia, p. PIV09-0040 (CD).

Kitchen, M.J., Lewis, R., Hooper, S.B., Wallace, M.J., Siu, K.K.W., Williams, I.M., Irvine, S., Morgan, M.J., Paganin, D.M., Pavlov, K.M., Yagi, N., Uesugi, K., 2007, Dynamic studies of lung fluid clearance with phase contrast imaging, Ninth International Conference on Synchrotron Radiation Instrumentation, 28/05/2006 to 02/06/2006, American Institute of Physics, USA, pp. 1903-1907.

Harding, R., Cock, M.L., Joyce, B.J., Louey, S.C., Wignarajah, D., Suzuki, K., Albuquerque, C.A., Maritz, G., Wallace, M.J., Hooper, S.B., 2003, Immediate and long-term consequences of induced low birthweight in sheep, Havemeyer Foundation Monograph Series No. 8, 13 March 2002 - 15 March 2002, R & W Publications (Newmarket) Limited, Newmarket UK, pp. 29-31.

Ward, J., Wallace, E.M., Hooper, S.B., Jenkin, G., 1999, Activin A: a novel marker of fetal wellbeing?, Proceedings of the 3rd Annual Congress of the Perinatal Society of Australia and New Zealand, Melbourne, Victoria, 21-24 March 1999, The Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 278.

Lines, A., Davey, M.G., Harding, R., Hooper, S.B., 1999, Continuous positive airway pressure (CPAP) at 10cm H<2O does not alter surfactant protein mRNA levels in 2 week old lambs, Perinatal Society of Australia and New Zealand 3rd Annual Congress, Melbourne, Victoria, 21-24 March 1999, The Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 110.

Lines, A., Davey, M.G., Harding, R., Hooper, S.B., 1999, Continuous positive airway pressure (CPAP) does not alter surfactant protein MRNA levels in 2 week old lambs, Respiratory and Critical Care Medicine, San Diego, CA, USA, 23-28 April 1999, American Thoracic Society, New York NY USA, p. 731A.

Joyce, B.J., Tester, M., Lines, A., Louey, S., Hooper, S.B., Harding, R., 1999, Effects of late gestational placental insufficiency on lung growth and pulmonary surfactant proteins in fetal sheep and 8 week old lambs, Perinatal Society of Australia and New Zealand 3rd Annual Congress, Melbourne VIC 21-24 March 1999, Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 295.

Probyn, M.E., Wallace, M.J., Hooper, S.B., 1999, Effects of tracheal obstruction on lung growth and development at mid gestation in fetal sheep, Perinatal Society of Australia and New Zealand 3rd Annual Congress, Melbourne, Victoria, The Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 116.

Hooper, S.B., Flecknoe, S.J., Maritz, G., Harding, R., 1999, Increased fetal lung expansion changes the proportion of alveolar epithelial cells (AEC); evidence for type-II to type-I cell differentiation, Respiratory and Critical Care Medicine, San Diego, CA, USA, 23-28 April 1999, American Thoracic Society, New York NY USA, p. 669A.

Lines, A., Gillett, A., Wallace, M.J., Phillips, I.D., Hooper, S.B., 1999, Release of tracheal obstruction increases SP-A and SP-C mRNA levels in the fetal sheep lung, Respiratory and Critical Care Medicine, San Diego, CA, USA, 23-28 April 1999, American Thoracic Society, New York NY USA, p. 663A.

Flecknoe, S.J., Harding, R., Maritz, G., Hooper, S.B., 1999, The effect of altered lung expansion on the proportion of alveolar epithelial cells in fetal sheep, Perinatal Society of Australia and New Zealand 3rd Annual Congress, Melbourne, Victoria, 21-24 March 1999, The Perinatal Society of Australia and New Zealand, Parramatta NSW, p. 117.

Harding, R., Cock, M., Hooper, S.B., Maritz, G., 1998, The effects of intrauterine compromise on respiratory development, Equine Veterinary Journal, Sydney Australia 9-11 February 1998, Equine Veterinary Journal Ltd, Newmarket UK, pp. 459-460.

Nardo, L., Hooper, S.B., Harding, R., 1997, Analysis of pulmonary cell types undergoing DNA synthesis following obstruction of the fetal trachea in sheep, First Annual Congress Perinatal Society of Australia and New Zealand, Femantle WA,16-24 March 1997, Perinat Soc of A&NZ, Wyeth Clin Meet Services, Parramatta NSW, p. A8.

Davey, M.G., Hooper, S.B., Johns, D.P., Harding, R., 1997, Measurements of lung function during early postnatal life in lambs with normal and hypoplastic lungs, First Annual Congress Perinatal Society of Australia & New Zealand Proceedings, Fremantle WA,16-24 March 1997, The Perinatal Soc of A&NZ, Wyeth Clin. Meet Serv, Paramatta NSW, p. A92.

Hooper, S.B., 1997, Occlusion of the fetal trachea as a treatment for fetal lung hypoplasia: A scientists perspective, First Annual Congress, Perinatal Society of Australia and New Zealand, Fremantle WA,16-24 March 1997, Perinat Soc of A&NZ, Wyeth Clin Meet Service, Parramatta NSW, p. A44.

Lines, A., Nardo, L., Hooper, S.B., 1997, Tracheal obstruction reduces surfactant protein A and C mRNA levels in the ovine fetal lung, First Annual Congress Perinatal Society of Australia and New Zealand, Fremantle WA, 16-24 March 1997, The Perinat Soc of A&NZ - Wyeth Clin. Meet Serv, Parramatta NSW, p. P14.

Other

Harding, R., Hooper, S.B., 2009, Lung growth and maturation, Fetal Medicine, vol monograph, Elsevier Ltd, UK, pp. 133-146.

Grants

Title:

Aeration of the Lung at Birth.

Investigators:

Hooper, S

Funding:

(2005 - 2009). Australian Nuclear Science & Technology Organisation (ANSTO).

Title:

Alveolar epithelial cell differentiation and apoptosis: effects of preterm birth, corticosteroids and stretch.

Investigators:

Hooper, S, Cole, T, Wallace, M

Funding:

(2005 - 2009). National Health & Medical Research Council (NHMRC).

Title:

Autoclave.

Investigators:

Perkins, A, Proske, U, Walker, D, Hooper, S

Funding:

(1999 - 1999). National Health & Medical Research Council (NHMRC).

Title:

Consequences of neonatal lung damage.

Investigators:

Hirst, J, Hooper, S, Crossley, K, Wintour-Coghlan, M

Funding:

(2004 - 2008). Rebecca L. Cooper Medical Research Foundation Ltd.

Title:

Control of Alveolar Epithelial Cell Differentiation Before and After Birth.

Investigators:

Hooper, S, Wallace, M

Funding:

(2002 - 2004). National Health & Medical Research Council (NHMRC).

Title:

Dynamic measurements of lung aeration at birth using phase contrast imaging.

Investigators:

Hooper, S

Funding:

(2006 - 2010). Australian Nuclear Science & Technology Organisation (ANSTO).

Title:

Dynamic phase contrast imaging of lung aeration after pre-term birth: the effects of surfactant and prolonged inspirations.

Investigators:

Wallace, M, Hooper, S, Siew, M

Funding:

(2007 - 2011). Australian Nuclear Science & Technology Organisation (ANSTO).

Title:

Dynamic phase contrast imaging of lung aeration at birth: the effects of positive end expiratory pressure (PEEP) and body position.

Investigators:

Hooper, S

Funding:

(2007 - 2011). Australian Nuclear Science & Technology Organisation (ANSTO).

Title:

Early Developmental Compromises: Effects on Postnatal Respiratory and Cardiovascular Function - Sprf.

Investigators:

Harding, R, Cock, M, Adamson, T, Stevenson, K, Anderson, W, Hooper, S, Henderson-Smart, D, Parkington, H, Horne, R, Walker, D

Funding:

(1999 - 2003). National Health & Medical Research Council (NHMRC).

Title:

Effects of positive pressure ventilation on oxygenation and pulmonary blood flow in the very preterm lamb.

Investigators:

Crossley, K, Dargaville, P, Hooper, S, Morley, C

Funding:

(2004 - 2008). Murdoch Childrens Research Institute.

Title:

Engineering Imaging and Supercomputer Prediction of Biofluid Flows.

Investigators:

Hourigan, K, Thompson, M, Hooper, S, Pearson, J, Evans, R, Denton, K, Leweke, T

Funding:

(2008 - 2012). Australian Research Council (ARC).

(2008 - 2012). Monash University.

Title:

From the synchrotron to the clinic: a novel functional lung imaging technology.

Investigators:

Fouras, A, Siu, K, Hooper, S, Watkins, D, Parsons, D, Zosky, G, Jenkins, B, Spanswick, D

Funding:

(2013 - 2016). National Health & Medical Research Council (NHMRC).

Title:

Identification of Genes Responsible for Lung Growth in the Fetus.

Investigators:

Hooper, S, Wallace, M

Funding:

(1997 - 1997). Rebecca L. Cooper Medical Research Foundation Ltd.

Title:

Identifying Novel Gene Expression in Physiologic Contexts: Neuron Survival and Fetal Lung Growth.

Investigators:

Nichols, N, Hooper, S, Cheema, S

Funding:

(1997 - 1997). Monash University.

Title:

Imaging Lung Motion For Studying The Dynamics Of Asthma and Its Treatments.

Investigators:

Hooper, S, Fouras, A, Lewis, R, Siu, K

Funding:

(2010 - 2014). American Asthma Foundation.

Title:

Imaging lung aeration and lung motion following very premature birth.

Investigators:

Hooper, S, Lewis, R, Fouras, A

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Title:

In Situ System Slide Thermal Cycler; Epi-fluorescence.

Investigators:

Nichols, N, Hooper, S, Clarke, I

Funding:

(1996 - 2000). National Health & Medical Research Council (NHMRC).

Title:

In-vivo detection of airway injury and disease using phase contrast X-ray velocimetry.

Investigators:

Fouras, A, Hooper, S, Lewis, R

Funding:

(2011 - 2015). Australian Research Council (ARC).

(2011 - 2015). Monash University.

Title:

Localised detection of early stage CF disease via quantitative imaging of lung motion.

Investigators:

Fouras, A, Parsons, D, Siu, K, Hooper, S, Donnelley, M

Funding:

(2011 - 2015). Cystic Fibrosis Australia.

Title:

Low dose methods for detecting early lung disease using x-ray phase contrast imaging.

Investigators:

Kitchen, M, Hooper, S

Funding:

(2011 - 2015). Australian Research Council (ARC).

(2011 - 2015). Monash University.

Title:

Nhmrc Research Fellowship - Continuing 143809.

Investigators:

Hooper, S

Funding:

(2001 - 2005). National Health & Medical Research Council (NHMRC).

Title:

Novel strategies for improving respiratory support and outcomes for preterm babies: ID 384100.

Investigators:

Harding, R, Morley, C, Hooper, S, Davis, P, Cole, T

Funding:

(2006 - 2010). National Health & Medical Research Council (NHMRC).

(2006 - 2012). National Health & Medical Research Council (NHMRC).

(2010 - 2014). National Health & Medical Research Council (NHMRC).

Title:

Olympus Cast-grid System - Equipment Grant 2000.

Investigators:

Bertram, J, Anderson, W, Wreford, N, Cheema, S, Hooper, S, Black, M, Kett, M

Funding:

(2001 - 2001). National Health & Medical Research Council (NHMRC).

Title:

Optimising bubble continuous positive airway pressure (CPAP) for preterm infants.

Investigators:

Moss, T, Polglase, G, Hooper, S, Kitchen, M, Fouras, A, Tatham, A

Funding:

(2012 - 2016). Australian Research Council (ARC).

(2012 - 2016). Fisher and Paykel Healthcare.

Title:

PCO Scientific CMOS Camera, "pco.edge".

Investigators:

Hooper, S, Siu, K, Fouras, A

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Title:

Phase Contrast X-ray Imaging of the Lung.

Investigators:

Lewis, R, Morgan, M, Hooper, S

Funding:

(2006 - 2010). Australian Research Council (ARC).

Title:

Phase contrast X-ray imaging of the lung at birth.

Investigators:

Hooper, S, Lewis, R, Thompson, B, Hourigan, K

Funding:

(2008 - 2011). National Health & Medical Research Council (NHMRC).

(2010 - 2014). National Health & Medical Research Council (NHMRC).

Title:

Phase contrast imaging of neonatal rabbit lungs.

Investigators:

Hooper, S, Wallace, M, Siu, K

Funding:

(2004 - 2008). Australian Nuclear Science & Technology Organisation (ANSTO).

Title:

Phase contrast x-ray imaging of the lung.

Investigators:

Islam, M, Wallace, M, Hooper, S

Funding:

(2010 - 2014). Australian Synchrotron.

Title:

Phase contrast x-ray imaging of the lung.

Investigators:

Wallace, M, Hooper, S, Lewis, R

Funding:

(2009 - 2013). Australian Synchrotron.

Title:

Physical Determinants of Fetal Lung Development.

Investigators:

Hooper, S

Funding:

(1998 - 2002). National Health & Medical Research Council (NHMRC).

Title:

Physical and endocrine control of fetal lung growth (Grant subsumed with project grantor 980933).

Investigators:

Hooper, S

Funding:

(1995 - 1999). National Health & Medical Research Council (NHMRC).

Title:

Physical determinants of lung development before and after birth.

Investigators:

Hooper, S, Wallace, M

Funding:

(2003 - 2007). National Health & Medical Research Council (NHMRC).

Title:

Principal research fellowship application.

Investigators:

Hooper, S

Funding:

(2002 - 2006). National Health & Medical Research Council (NHMRC).

(2007 - 2011). National Health & Medical Research Council (NHMRC).

(2009 - 2013). National Health & Medical Research Council (NHMRC).

(2010 - 2014). National Health & Medical Research Council (NHMRC).

Title:

Reducing cerebral palsy by improving immediate resuscitation at preterm delivery.

Investigators:

Polglase, G, Kluckow, M, Miller, S, Moss, T, Hooper, S, Walker, D

Funding:

(2011 - 2014). Cerebral Palsy Foundation.

Title:

Role of Growth Hormone in the Growth and Development of the Fetal Lung.

Investigators:

Hooper, S

Funding:

(2000 - 2000). Australian Research Council (ARC).

Title:

Role of Physical Forces in the Determination of Pulmonary Epithelial Cell Phenotypes (990478).

Investigators:

Hooper, S, Harding, R

Funding:

(1999 - 2001). National Health & Medical Research Council (NHMRC).

Title:

X-ray converter with interchangeable objective lenses and interchangeable scintillators.

Investigators:

Hooper, S, Lewis, R, Hourigan, K, Siu, K, Fouras, A

Funding:

(2009 - 2013). National Health & Medical Research Council (NHMRC).

(2010 - 2014). National Health & Medical Research Council (NHMRC).

Title:

Advanced NanoBiomaterials Imaging Facility.

Investigators:

Caruso, F, Hourigan, K, Stevens, G, Sridhar, T, Kent, S, Fouras, A, Qiao, G, Dunstan, D, Thouas, G, Hooper, S, O'Connor, A, Johnston, A, Stadler, B, Evans, R, Gras, S, Denton, K, Pearson, J, Such, G, Blencowe, A, Kitchen, M, Siu, K

Funding:

(2009 - 2013). Australian Research Council (ARC).

(2009 - 2013). Monash University.

Title:

Role of proteoglycans in fetal lung maturation.

Investigators:

Hooper, S, Fosang, A

Funding:

(2003 - 2007). National Health & Medical Research Council (NHMRC).

Title:

Improved respiratory support and outcomes for very preterm babies.

Investigators:

Hooper, S, Davis, P, Doyle, L, Harding, R, Cole, T, Moss, T

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

(2011 - 2015). The University of Melbourne.

(2012 - 2016). The University of Melbourne.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Mechanisms regulating the increase in pulmonary blood flow at birth.

Supervisors:

Hooper, S (Main), Pearson, J (Associate), Polglase, G (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The effects of different methods of asphyxia and sustained inflation strategies on the cardiorespiratory system in near-term asphyxiated lambs..

Supervisors:

Hooper, S (Main), Polglase, G (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The effects of different sustained inflation pressures and durations on the cardiovascular and respiratory systems at birth..

Supervisors:

Hooper, S (Main), Moss, T (Associate), Polglase, G (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

The optimisation of high frequency ventilation as an ideal ventilation strategy.

Supervisors:

Fouras, A (Main), Hooper, S (Associate), Hourigan, K (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

What are the mechanisms responsible for the male disadvantage in cardio-respiratory function following preterm birth?.

Supervisors:

De Matteo, R (Joint-co), Sozo, F (Joint), Hooper, S (Associate).

Completed Supervision

Student:

Allison, B.

Program of Study:

In utero ventilation: effects on lung morphology and pulmonary haemodynamics in immature fetal sheep. (PHD) 2008.

Supervisors:

Hooper, S (Main), Crossley, K (Associate), Flecknoe, S (Associate).

Student:

Boland, R.

Program of Study:

FACTORS AFFECTING STRUCTURAL DEVELOPMENT OF THE LUNG IN FETAL SHEEP. (PHD) 2002.

Supervisors:

Hooper, S (Main).

Student:

Brew, N.

Program of Study:

Mechanical ventilation of the very immature lung: mechanisms of injury and repair. (PHD) 2012.

Supervisors:

Harding, R (Joint-Co), Hooper, S (Joint).

Student:

Davey, M.

Program of Study:

RESPITORY FUNCTION AND LUNG STRUCTURE IN LAMBS FOLLOWING IN UTERO TREATMENT OF LUNG HYPOPLASIA BY TRACHEAL OBSTRUCTION. (PHD) 2000.

Supervisors:

Harding, R (Main), Hooper, S (Associate).

Student:

Dharmakumara, M.

Program of Study:

. 2008.

Supervisors:

Thompson, B (Main), Hooper, S (Associate).

Student:

Filby, C.

Program of Study:

Factors regulating alveolar development in the ovine fetus. (PHD) 2008.

Supervisors:

Hooper, S (Joint), Wallace, M (Joint-Co).

Student:

Flecknoe, S.

Program of Study:

REGULATION OF THE ALVEOLAR EPITHELIAL CELL PHENOTYPES IN FETAL AND POSTNATAL SHEEP: EFFECTS OF PHYSICAL AND ENDOCRINE FACTORS. (PHD) 2004.

Supervisors:

Hooper, S (Main), Harding, R (Associate).

Student:

Halil, G.

Program of Study:

ALTERATION IN GENE EXPRESSION DURING EXPANSION-INDUCED FETAL LUNG GROWTH. (Masters) 2002.

Supervisors:

Hooper, S (Main).

Student:

Joyce, B.

Program of Study:

ELASTIN SYNTHESIS IN THE FETAL SHEEP LUNG IN VIVO: EFFECTS OF PHYSICAL, METABOLIC AND ENDOCRINE FACTORS. (PHD) 2004.

Supervisors:

Harding, R (Main), Hooper, S (Associate).

Student:

Lines, A.

Program of Study:

THE REGULATION OF SURFACTANT PROTEINS BY ALTERATIONS IN LUNG EXPANSION IN FETAL AND NEWBORN SHEEP. (PHD) 2000.

Supervisors:

Hooper, S (Main), Nichols, N (Associate).

Student:

Mcdougall, A.

Program of Study:

The role of Trop2 in fetal lung development. (PHD) 2012.

Supervisors:

Hooper, S (Joint-Co), Wallace, M (Joint).

Student:

Polglase, G.

Program of Study:

INFLUENCE OF INTRA-LUMINAL PRESSURE ON PULMONARY HAEMODYNAMICS IN FETAL SHEEP.. (PHD) 2005.

Supervisors:

Hooper, S (Joint-Co), Wallace, M (Joint).

Student:

Probyn, M.

Program of Study:

LUNG INFLAMMATION AND RESPIRATORY FUNCTION DURING RESUSCITATION AND MECHANICAL VENTILATION OF PRETERM LAMBS. (PHD) 2003.

Supervisors:

Hooper, S (Main), Wallace, M (Joint).

Student:

Schmoelzer, G.

Program of Study:

Monitoring respiratory function during neonatal resuscitation. (PHD) 2010.

Supervisors:

Hooper, S (Main).

Student:

Siew, M.

Program of Study:

Lung aeration at birth. (PHD) 2010.

Supervisors:

Hooper, S (Main), Wallace, M (Associate).

Student:

Sozo, F.

Program of Study:

Indentification and characterization of genes that regulate growth and maturation of the ovine fetal lung. (PHD) 2007.

Supervisors:

Hooper, S (Joint-Co), Wallace, M (Joint).

Student:

Suzuki, K.

Program of Study:

EFFECTS OF LUNG HYPOPLASIA ON PULMONARY VASCULAR DEVELOPMENT IN FETAL SHEEP. (PHD) 2005.

Supervisors:

Harding, R (Joint-Co), Hooper, S (Joint).