Ms Victoria McLeod - Researcher Profile

Biography

Position

Research Assistant
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Delivery, Disposition and Dynamics
Monash Institute of Pharmaceutical Sciences

Qualifications

BSC (PHARMACOLOGY) FIRST CLASS HONORS

Institution: University of Otago, New Zealand

Year awarded: 2008

Publications

Journal Articles

Kaminskas, L., McLeod, V., Kelly, B., Sberna, G., Boyd, B., Williamson, M., Owen, D., Porter, C., 2012, A comparison of changes to doxorubicin pharmacokinetics, antitumour activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems, Nanomedicine-Nanotechnology Biology And Medicine [P], vol 8, issue 1, Elsevier, Netherlands, pp. 103-111.

Kaminskas, L.M., McLeod, V.M., Porter, C.J., Boyd, B.J., 2012, Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulation, Molecular Pharmaceutics [P], vol 9, issue 3, American Chemical Society, USA, pp. 355-373.

Kaminskas, L.M., McLeod, V.M., Kelly, B.D., Cullinane, C.M., Sberna, G., Williamson, M., Boyd, B.J., Owen, D.J., Porter, C.J., 2012, Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumour models, Molecular Pharmaceutics [P], vol 9, American Chemical Society, United States, pp. 422-432.

Kaminskas, L., McLeod, V., Sberna, G., Boyd, B., Owen, D., Porter, C., 2011, Capping methotrexate alpha-carboxyl groups enhances systemic exposure and retains the cytotoxicity of drug conjugated PEGylated polylysine dendrimers, Molecular Pharmaceutics [E], vol 8, American Chemical Society, USA, pp. 338-349.

Kaminskas, L., Kelly, B., McLeod, V., Sberna, G., Owen, D., Boyd, B., Porter, C., 2011, Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker, Journal of Controlled Release [P], vol 152, Elsevier Science Publishers, The Netherlands, pp. 241-248.

Kaminskas, L., McLeod, V., Porter, C., Boyd, B., 2011, Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearance, Journal of Pharmaceutical Sciences [P], vol 11, John Wiley & Sons Inc, USA, pp. 5069-5077.

Kaminskas, L.M., Kota, J., McLeod, V.M., Kelly, B.D., Karellas, P., Porter, C.J., 2009, PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats, Journal of Controlled Release [P], vol 140, issue 2, Elsevier B.V., The Netherlands, pp. 108-116.

Kaminskas, L.M., Kelly, B.D., McLeod, V.M., Boyd, B.J., Krippner, G.Y., Williams, E., Porter, C.J., 2009, Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly-L-lysine dendrimers, Molecular Pharmaceutics [P], vol 6, issue 4, American Chemical Society, USA, pp. 1190-1204.

Activities

Affiliations with institutes

Drug Delivery, Disposition and Dynamics
Monash Institute of Pharmaceutical Sciences