Prof Moira O'Bryan - Researcher Profile

Biography

Professor Moira O'Bryan leads the Male Infertility & Germ Cell Biology Laboratory in the Department of Anatomy and Developmental Biology. This group studies sperm development and function and the causes of human male infertility.

Moira is also Deputy Head, Research, in the Department of Anatomy and Developmental Biology.

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Keywords

sperm development, sperm function, male infertility,

Qualifications

DOCTOR OF PHILOSOPHY

Institution: University of Melbourne

Year awarded: 2005

SCIENCE (HONS)

Institution: UNIVERSITY OF MELBOURNE

Year awarded: 1989

Publications

Book Chapters

Jamsai, D., O'Bryan, M.K., 2010, Mouse models as tools in fertility research and male-based contraceptive development, in Fertility Control (Handbook of Experimental Pharmacology), eds Ursula-F Habenicht and R John Aitken, Springer, USA, pp. 179-194.

O'Bryan, M.K., Hedger, M.P., 2008, Inflammatory Networks in the Control of Spermatogenesis - Chronic Inflammation in a Immunologically Privileged Tissue?, in Molecular Mechanisms in Spermatogenesis (Volume 636), eds C Y Cheng, Landes Bioscience, USA, pp. 92-114.

Kerr, J.B., Loveland, K.A.L., O'Bryan, M.K., de Kretser, D.M., 2006, Cytology of the testis and intrinsic control mechanisms, in Knobil and Neill's Physiology of Reproduction, eds Jimmy D Neill, John R G Challis, David M de Kretser, Donald W Pfaff, JoAnne S Richards, Tony M Plant and Paul M Wassarman, Elsevier, London UK, pp. 827-947.

de Kretser, D.M., Meehan, T., O'Bryan, M.K., Wreford, N.G., McLachlan, R.D., Loveland, K.L., 2000, Regulatory mechanisms in mammalian spermatogenesis, in Testis, epididymis and technologies in the year 2000, Springer-Verlag, Berlin Germany, pp. 87-106.

Journal Articles

Jamsai, D., O'Connor, A., Deboer, K.D., Clark, B., Smith, S.J., Browne, C.M., Bensley, J.G.A., Merriman, J.A., Yuen, W.S., Koopman, P.A., Jones, K.T., O'Bryan, M.K., 2013, Loss of GGN Leads to Pre-Implantation Embryonic Lethality and Compromised Male Meiotic DNA Double Strand Break Repair in the Mouse, PLoS ONE [P], vol 8, issue 2, Public Library of Science, USA, pp. 1-7.

O'Donnell, L., Rhodes, D., Smith, S.J., Merriner, D.J., Clark, B.J., Borg, C.L., Whittle, B., O'Connor, A.E., Smith, L.B., McNally, F.J., de Kretser, D.M., Goodnow, C.C., Ormandy, C.J., Jamsai, D., O'Bryan, M.K., 2012, An essential role for katanin p80 and microtubule severing in male gamete production, Plos Genetics [P], vol 8, issue 5 (Art. ID: e1002698), Public Library of Science, USA, pp. 1-12.

Yuen, W.S., Merriman, J.A., O'Bryan, M.K., Jones, K.T., 2012, DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes, PLoS ONE [P], vol 7, issue 8 (Art. No.: e43875), Public Library of Science, USA, pp. 1-9.

O'Bryan, M.K., Grealy, A., Stahl, P.J., Schlegel, P.N., McLachlan, R.L., Jamsai, D., 2012, Genetic variants in the ETV5 gene in fertile and infertile men with nonobstructive azoospermia associated with Sertoli cell-only syndrome, Fertility and Sterility [P], vol 98, issue 4 (Art. ID: e1-3), Elsevier Inc., USA, pp. 827-835.e3.

Smith, L.B., Milne, L., Nelson, N., Eddie, S., Brown, P., Atanassova, N., O'Bryan, M.K., O'Donnell, L., Rhodes, D., Wells, S., Napper, D., Nolan, P.M., Lalanne, Z., Cheeseman, M., Peters, J., 2012, KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility, PLoS Genetics [E], vol 8, issue 5 (Art. ID: e1002697), Public Library of Science, USA, pp. 1-14.

Lo, C.Y.J., Jamsai, D., O'Connor, A.E., Borg, C.L., Clark, B., Whisstock, J.C., Field, M.C., Adams, V., Ishikawa, T., Aitken, R.J., Whittle, B., Goodnow, C.C., Ormandy, C.J., O'Bryan, M.K., 2012, RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly, PLoS Genetics [E], vol 8, issue 10 (Art. No.: e1002969), Public Library of Science, USA, pp. 1-11.

Gibbs, G., Orta, G., Reddy, T., Koppers, A., Martinez-Lopez, P., de la Vega-Beltran, J., Lo, J., Veldhuis, N., Jamsai, D., Mcintyre, P., Darszon, A., O'Bryan, M., 2011, Cysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm function, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 108, issue 17, National Academy of Sciences, USA, pp. 7034-7039.

Zamudio, N., Scott, H., Wolski, K., Lo, J., Law, C., Leong, D., Kinkel, S., Chong, S., Jolley, D., Smyth, G., de Kretser, D., Whitelaw, E., O'Bryan, M., 2011, DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription, PLoS ONE [P], vol 6, issue 3 (Art. No: e18276), Public Library of Science, USA, pp. 1-12.

Jamsai, D., Sarraj, M., Merriner, D.J., Drummond, A.E., Jones, K.T., McLachlan, R., O'Bryan, M.K., 2011, GGN1 in the testis and ovary and its variance within the Australian fertile and infertile male population, International Journal Of Andrology [P], vol 34, issue 6 (Part 1), Wiley-Blackwell Publishing Ltd, UK, pp. 624-632.

Liu, J., Ashton, M., Sumer, H., O'Bryan, M., Brodnicki, T., Verma, P., 2011, Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts, Diabetes [P], vol 60, issue 5, American Diabetes Association, United States, pp. 1393-1398.

Redgrove, K., Anderson, A., Dun, M., McLaughlin, E., O'Bryan, M., Aitken, R., Nixon, B., 2011, Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae, Developmental Biology [P], vol 356, issue 2, Academic Press Inc. Elsevier Science, USA, pp. 460-474.

McLachlan, R., Ishikawa, T., Osianlis, T., Robinson, P., Merriner, D.J., Healy, D.L., de Kretser, D.M., O'Bryan, M.K., 2011, Normal live birth after testicular sperm extraction and intracytoplasmic sperm injection in variant primary ciliary dyskinesia with completely immotile sperm and structurally abnormal sperm tails, Fertility and Sterility [P], vol E, Elsevier Inc., United States, pp. 1-6.

Nixon, B., Mitchell, L.A., Anderson, A., McLaughlin, E.A., O'Bryan, M.K., Aitken, R.J., 2011, Proteomic and functional analysis of human sperm detergent resistant membranes, Journal Of Cellular Physiology [P], vol 226, issue 10, John Wiley & Sons, Inc., USA, pp. 2651-2665.

O'Donnell, L., Nicholls, P., O'Bryan, M., McLachlan, R.I., Stanton, P., 2011, Spermiation: The process of sperm release, Spermatogenesis [P], vol 1, issue 1, Landes BioScience, USA, pp. 14-35.

Martinez-Lopez, P., Trevino, C.L., de la Vega-Beltran, J.L., De Blas, G., Monroy, E., Beltran, C., Orta, G., Gibbs, G., O'Bryan, M.K., Darszon, A., 2011, TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction, Journal Of Cellular Physiology [P], vol 226, issue 6, John Wiley & Sons, Inc., USA, pp. 1620-1631.

Sanchez-Partida, L., Kelly, R., Sumer, H., Lo, C., Aharon, R., Holland, M., O'Bryan, M., St John, J., 2011, The generation of live offspring from vitrified oocytes, PLoS ONE [P], vol 6, issue 6 (Art. No: e21597), Public Library of Science, United States, pp. 1-11.

Koppers, A., Reddy, T., O'Bryan, M., 2011, The role of cysteine-rich secretory proteins in male fertility, Asian Journal of Andrology [P], vol 13, issue 1, Nature Publishing Group, USA, China, pp. 111-117.

Jamsai, D., Rijal, S., Bianco, D.M., O'Connor, A., Merriner, D.J., Smith, S.J., Gibbs, G.M., O'Bryan, M.K., 2010, A novel protein, sperm head and tail associated protein (SHTAP), interacts with cysteine-rich secretory protein 2 (CRISP2) during spermatogenesis in the mouse, Biology Of The Cell [P], vol 102, issue 2, Portland Press Ltd, UK & Germany, pp. 93-106.

Wilson, G.R., Wang, H.X., Egan, G.F., Robinson, P.J., Delatycki, M.B., O'Bryan, M.K., Lockhart, P.J., 2010, Deletion of the Parkin co-regulated gene causes defects in ependymal ciliary motility and hydrocephalus in the quakingviable mutant mouse, Human Molecular Genetics [P], vol 19, issue 8 (Art. No. ddq031), Oxford University Press, UK, pp. 1593-1602.

Jamsai, D., O'Bryan, M.K., 2010, Genome-wide ENU mutagenesis for the discovery of novel male fertility regulators, Systems Biology in Reproductive Medicine [P], vol 56, issue 3, Informa Healthcare, UK, pp. 246-259.

Gibbs, G., Lo, C.Y.J., Nixon, B., Jamsai, D., O'Connor, A., Rijal, S., Sanchez-Partida, L.G., Hearn, M.T.W., Bianco, D.M., O'Bryan, M.K., 2010, Glioma pathogenesis-related 1-like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding, Endocrinology [P], vol 151, issue 5, The Endocrine Society, USA, pp. 2331-2342.

Jamsai, D., O'Bryan, M.K., 2010, Mouse models in male fertility research, Asian Journal of Andrology [P], vol 13, Nature Publishing Group, USA, China, pp. 139-151.

McLachlan, R.I., O'Bryan, M.K., 2010, State of the art for genetic testing of infertile men, Journal of Clinical Endocrinology and Metabolism [P], vol 95, issue 3, The Endocrine Society, USA, pp. 1013-1024.

Cowin, P., Gold, E., Aleksova, J., O'Bryan, M., Foster, P., Scott, H., Risbridger, G., 2010, Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism, Endocrinology [P], vol 151, issue 2, The Endocrine Society, United States, pp. 783-792.

Gold, E.J., Jetly, N., O'Bryan, M.K., Meachem, S.J., Srinivasan, D., Behuria, S., Sanchez-Partida, L.G., Woodruff, T.K., Hedwards, S.L., Wang, H., McDougall, H., Casey, V., Niranjan, B., Patella, S., Risbridger, G.P., 2009, Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo, The American Journal of Pathology, vol 174, issue 1, American Society for Investigative Pathology, USA, pp. 184-195.

Hubert, F., Kinkel, S.A., Crewther, P.E., Cannon, P.Z., Webster, K.E., Link, M., Uibo, R., O'Bryan, M.K., Meager, A., Forehan, S.P., Smyth, G.K., Mittaz, L., Antonarakis, S.E., Peterson, P., Heath, W.R., Scott, H.S., 2009, Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype, Journal of Immunology, vol 182, issue 6, American Association of Immunologists, USA, pp. 3902-3918.

Wilson, G.R., Sim, M.L., Brody, K.M., Taylor, J.M., McLachlan, R., O'Bryan, M.K., Delatycki, M.B., Lockhart, P.J., 2009, Molecular analysis of the PArkin co-regulated gene and association with male infertility, Fertility & Sterility, vol 4.167, issue 7, Elsevier Inc, USA, pp. 2262-2268.

Krausz, C., Giachini, C., Xue, Y., O'Bryan, M.K., Gromoll, J., Meyts, E.R., Oliva, R., Aknin-Seifer, I., Erdei, E., Jorgensen, N., Simoni, M., Ballesca, J.L., Levy, R., Balercia, G., Piomboni, P., Nieschlag, E., Forti, G., McLachlan, R., Tyler-Smith, C., 2009, Phenotypic variation within European carriers of the Y-chromosomal gr/gr deletion is independent of Y-chromosomal background, Journal of Medical Genetics, vol 46, issue 1, BMJ Group, UK, pp. 21-31.

Borg, C.L., Wolski, K.M., Gibbs, G.M., O'Bryan, M.K., 2009, Phenotyping male infertility in the mouse: How to get the most out of a 'non-performer', Human Reproduction Update [P], vol 16, Oxford University Press, UK & Belgium, pp. 205-224.

Cotton, L.M., O'Bryan, M.K., Hinton, B.T., 2008, Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction, Endocrine Reviews, vol 29, issue 2, The Endocrine Society, United States, pp. 193-216.

Jamsai, D., Bianco, D.M., Smith, S.J., Merriner, D.J., Ly-Huynh, J.D., Herlihy, A., Niranjan, B., Gibbs, G.M., O'Bryan, M.K., 2008, Characterization of gametogenetin 1 (GGN1) and its potential role in male fertility through the interaction with the ion channel regulator, cysteine-rich secretory protein 2 (CRISP2) in the sperm tail, Reproduction, vol 135, issue 6, Bio Scientifica Ltd, England, pp. 751-759.

Reddy, T., Gibbs, G.M., Merriner, D.J., Kerr, J.B., O'Bryan, M.K., 2008, Cysteine-rich secretory proteins are not exclusively expressed in the male reproductive tract, Developmental Dynamics, vol 237, issue 11, Wiley-Liss, United States, pp. 3313-3323.

Zamudio, N.M., Chong, S., O'Bryan, M.K., 2008, Epigenetic regulation in male germ cells, Reproduction, vol 136, BioScientifica Ltd, England, pp. 131-146.

Walsh, A.J., Whelan, D., Bielanowicz, A., Skinner, B.J., Aitken, R.J., O'Bryan, M.K., Nixon, B., 2008, Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse, Biology of Reproduction, vol 78, Society Study of Reproduction, United States, pp. 983-993.

McLachlan, R., Aitken, R.J., Cram, D.S., Krausz, C., O'Bryan, M.K., 2008, LETTER TO THE EDITOR: Need for Standardization and Confirmation of STS Deletions on the Y Chromosome, Fertility & Sterility, vol 90, issue 2, Elsevier Inc, USA, pp. 463-464.

Jamsai, D., Reilly, A., Smith, S.J., Gibbs, G.M., Baker, H.W.G., McLachlan, R.I., de Kretser, D.M., O'Bryan, M.K., 2008, Polymorphisms in the human cysteine-rich secretory protein 2 (CRISP2) gene in Australian Men, Human Reproduction, vol 23, issue 9, Oxford University Press, UK, pp. 2151-2159.

O'Bryan, M.K., Takada, S., Borg, C.L., Scott, G., Harada, S., Ray, M.K., Dai, Q., Wilhelm, D., de Kretser, D.M., Eddy, E.M., Koopman, P.A., Mishina, Y., 2008, Sox8 is a critical regulator of adult sertoli cell function and male fertility, Developmental Biology, vol 316, issue 2, Academic Press Inc Elsevier Science, United States, pp. 359-370.

Gibbs, G.M., Roelants, K., O'Bryan, M.K., 2008, The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins - roles in reproduction, cancer, and immune defense, Endocrine Reviews, vol 29, issue 7, Endocrine Society, United States, pp. 865-897.

Winnall, W.R., Ali, U., O'Bryan, M.K., Hirst, J.J., Whiley, P.A.F., Muir, J.A., Hedger, M.P., 2007, Constitutive expression of prostaglandin-endoperoxide synthase 2 by somatic and spermatogenic cells is responsible for prostaglandin E2 production in the adult rat testis, Biology of Reproduction, vol 76, issue 5, Soc Study Reproduction, Madison USA, pp. 759-768.

Gibbs, G.M., O'Bryan, M.K., 2007, Cysteine rich secretory proteins in reproduction and venom, Society Of Reproduction & Fertility Supplement, vol 65, Nottingham University Press, England, pp. 261-267.

Gibbs, G.M., Bianco, D.M., Jamsai, D., Herlihy, A., Ristevski, S., Aitken, R.J., de Kretser, D.M., O'Bryan, M.K., 2007, Cysteine-rich secretory protein 2 binds to mitogen-activated protein kinase kinase kinase 11 in mouse sperm, Biology of Reproduction, vol 77, issue 1, Soc Study Reproduction, Madison USA, pp. 108-114.

Chong, S., Vickaryous, N., Ashe, A., Zamudio, N.M., Youngson, N., Hemley, S., Stopka, T., Skoultchi, A., Matthews, J.M., Scott, H.S., de Kretser, D.M., O'Bryan, M.K., Blewitt, M., Whitelaw, E., 2007, Modifiers of epigenetic reprogramming show paternal effects in the mouse, Nature Genetics, vol 39, issue 5, Nature Publishing Group, New York, pp. 614-622.

Kennedy, C.L., Koopman, P.A., Mishina, Y., O'Bryan, M.K., 2007, Sox8 and sertoli-cell function, Annals of the New York Academy of Sciences, vol 1120, Wiley-Blackwell Publishing Inc, USA, pp. 104-113.

Shehu-Xhilaga, M., Kent, S.J., Batten, J., Ellis, S., Van der Meulen, J.D., O'Bryan, M.K., Cameron, P.U., Lewin, S.R., Hedger, M.P., 2007, The testis and epididymis are productively infected by SIV and SHIV in juvenile macaques during the post-acute stage of infection, Retrovirology, vol 4, issue 1, BioMed Central Ltd, United Kingdom, pp. 1-13.

Kennedy, C.L., O'Connor, A.E., Sanchez-Partida, L.G., Holland, M.K., Goodnow, C.C., de Kretser, D.M., O'Bryan, M.K., 2006, A repository of ENU mutant mouse lines and their potential for male fertility research, Molecular Human Reproduction, vol 11, issue 12, Oxford University Press, UK, pp. 871-880.

Cotton, L.M., Gibbs, G.M., Sanchez-Partida, L.G., Morrison, J.R., de Kretser, D.M., O'Bryan, M.K., 2006, FGRF-1 signaling is involved in spermiogenesis and sperm capacitation, Journal of Cell Science, vol 119, issue 1, The Company of Biologists Ltd, Cambridge UK, pp. 75-84.

Arsov, T., Silva, D.G., O'Bryan, M.K., Sainsbury, A., Lee, N.J., Borg, C.L., Manji, S.S.M., Nelms, K., Liu, C., Vinuesa, C.G., de Kretser, D.M., Goodnow, C.C., Petrovsky, N., 2006, Fat Aussie - A new Alstrom syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis, Molecular Endocrinology, vol 20, issue 7, Endocrine Society, USA, pp. 1610-1622.

O'Bryan, M.K., de Kretser, D.M., 2006, Mouse models for genes involved in impaired spermatogenesis, International Journal of Andrology, vol 29, issue 1, American Society of Andrology, United States, pp. 76-89.

Kennedy, C.L., O'Bryan, M.K., 2006, N-ethyl-N-nitrosourea (ENU) mutagenesis and male fertility research, Human Reproduction Update, vol 12, issue 3, Oxford University Press, Oxford England, pp. 293-301.

Gibbs, G.M., Scanlon, M.J., Swarbrick, J.D., Curtis, S., Gallant, E., Dulhunty, A.F., O'Bryan, M.K., 2006, The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling, Journal of Biological Chemistry, vol 281, issue 7, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 4156-4163.

Nixon, B., MacIntyre, D., Mitchell, L.A., Gibbs, G., O'Bryan, M.K., Aitken, R.J., 2006, The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors, Biology of Reproduction, vol 74, Society for the Study of Reproduction, USA, pp. 275-287.

O'Bryan, M.K., Gerdprasert, O., Nikolic-Paterson, D.J., Meinhardt, A., Muir, J.A., Foulds, L.M., Phillips, D.J., de Kretser, D.M., Hedger, M.P., 2005, Cytokine profiles in the testes of rats treated with lipopolysaccharide reveal localized suppression of inflammatory responses, American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol 288, issue 6, Amercan Physiological Society, USA, pp. R1744-R1755.

Webster, K.E., O'Bryan, M.K., Fletcher, S., Crewther, P.E., Aapola, U., Craig, J., Harrison, D.K., Aung, H., Phutikanit, N., Lyle, R., Meachem, S.J., Antonarakis, S.E., de Kretser, D.M., Hedger, M.P., Peterson, P., Carroll, B.J., Scott, H.S., 2005, Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis, Proceedings of the National Academy of Sciences, vol 102, issue 11, National Academy Sciences, USA, pp. 4068-4073.

Lynch, M., Cram, D.S., Reilly, A., O'Bryan, M.K., Baker, H.W.G., de Kretser, D.M., McLachlan, R., 2005, The Y chromosome gr/gr subdeletion is associated with male infertility, Molecular Human Reproduction, vol 11, issue 7, Oxford University Press, Oxford England, pp. 507-512.

Read, S.H., O'Bryan, M.K., Goodnow, C.C., 2005, Unlocking the mammalian "phenome double right arrow genome" code with the support of the Australian Phenomics Facility, Tissue Antigens, vol 66, issue 5, Blackwell Publishing, Oxford England, p. 361.

Gold, E.J., O'Bryan, M.K., Mellor, S.L., Cranfield, M., Risbridger, G.P., Groome, N.P., Fleming, J.S., 2004, Cell-specific expression of in the rat reproductive tract, adrenal and liver, Molecular and Cellular Endocrinology, vol 222, Elsevier Science, Ireland, pp. 61-69.

Buzzard, J.J., Loveland, K.A.L., O'Bryan, M.K., O'Connor, A., Bakker, M.R., Hayashi, T., Wreford, N.G., Morrison, J.R., de Kretser, D.M., 2004, Changes in Circulating and Testicular Levels of Inhibin A and B and Activin A During Postnatal Development in the Rat, Endocrinology, vol 145, issue 7, The Endocrine Society, USA, pp. 3532-3541.

Krebs, D.L., Metcalf, D., Merson, T.D., Voss, A.K., Thomas, T., Zhang, J., Rakar, S., O'Bryan, M.K., Willson, T.A., Viney, E.M., Mielke, L.A., Nicola, N.A., Hilton, D., Alexander, W.S., 2004, Development of Hydrocephalus in mice lacking SOCS7, Proceedings of the National Academy of Sciences of the USA, vol 101, issue 43, National Academy of Sciences, USA, pp. 15446-15451.

Cram, D.S., Lynch, M., O'Bryan, M.K., Salvado, C.L., McLachlan, R., de Kretser, D.M., 2004, Genetic screening of infertile men, Reproduction, Fertility and Development, vol 16, CSIRO Publishing, Vic Australia, pp. 573-580.

Kennedy, C.L., Sebire, K.L., de Kretser, D.M., O'Bryan, M.K., 2004, Human sperm associated antigen 4 (SPAG4) is a potential cancer marker, Cell and Tissue Research, vol 315, issue 2, Springer-Verlag, Germany, pp. 279-283.

Kennedy, C.L., Sebire, K.L., de Kretser, D.M., O'Bryan, M.K., 2004, Human sperm associated antigen 4 (SPAG4) is a potential cancer marker, Cell and Tissue Research, vol 315, issue 2, Springer-Verlag, Germany, pp. 279-282.

O'Bryan, M.K., Foulds, L.M., Cannon, J.F., Winnall, W.R., Muir, J.A., Sebire, K.L., Smith, A.I., Keah, H.H., Hearn, M.T.W., de Kretser, D.M., Hedger, M.P., 2004, Identification of a Novel Apolipoprotein, ApoN, in Ovarian Follicular Fluid, Endocrinology, vol 145, issue 11, The Endocrine Society, USA, pp. 5231-5242.

Aitken, R.J., Baker, M.A., O'Bryan, M.K., 2004, Shedding Light on Chemiluminescence: The Application of Chemiluminescence in Diagnostic Andrology, Journal of Andrology, vol 25, issue 4, American Society of Andrology Inc, USA, pp. 455-465.

Douglas, G.C., O'Bryan, M.K., Hedger, M.P., Lee, D.K.L., Yarski, M.A., Smith, A.I., Lew, R., 2004, The Novel Angiotensin-Converting Enzyme (ACE) Homolog, ACE2, Is Selectively Expressed by Adult Leydig Cells of the Testis, Endocrinology, vol 145, issue 10, The Endocrine Society, USA, pp. 4703-4711.

McManamny, P., Chy, H.S., Finkelstein, D., Craythorn, R.G., Crack, P.J., Kola, I., Cheema, S., Horne, M.K., Wreford, N.G., O'Bryan, M.K., de Kretser, D.M., Morrison, J.R., 2002, A mouse model of spinal and bulbar muscular atrophy, Human Molecular Genetics, vol 11, issue 18, Oxford University Press, Oxford UK, pp. 2103-2111.

Gerdprasert, O., O'Bryan, M.K., Nikolic-Paterson, D.J., Sebire, K.L., de Kretser, D.M., Hedger, M.P., 2002, Expression of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor in normal and inflamed rat testis, Molecular Human Reproduction, vol 8, issue 6, Oxford University Press, Oxford UK, pp. 518-524.

Hickox, D., Gibbs, G., Morrison, J.R., Sebire, K.L., Edgar, K., Keah, H., Alter, K., Loveland, K.L., Hearn, M.T.W., de Kretser, D.M., O'Bryan, M.K., 2002, Identification of a novel testis-specific member of the phosphatidykethanolamine binding protein family, pebp-2, Biology of Reproduction, vol 67, Society for the study of Reproduction, Madison WI USA, pp. 917-927.

Gerdprasert, O., O'Bryan, M.K., Muir, J.A., Caldwell, A.M., Schlatt, S., de Kretser, D.M., Hedger, M.P., 2002, The response of testicular leukocytes to lipopolysaccharide-induced inflammation: further evidence for heterogeneity of the testicular macrophage population, Cell and Tissue Research, vol 308, issue 2, Springer-Verlag, New York NY USA, pp. 277-285.

Dickins, R.A., Frew, I.J., House, C.M., O'Bryan, M.K., Holloway, A.J., Haviv, I., Traficante, N., de Kretser, D.M., Bowtell, D.D.L., 2002, The ubiquitin ligase component sia 1a is required for completion of meiosis 1 in the male mouse, Molecular and Cellular Biology, vol 22, American Society for Microbiology, Washington DC USA, pp. 2294-2303.

Gow, R.M., O'Bryan, M., Canny, B., Ooi, G.T., Hedger, M., 2001, Differential effects of dexamethasone treatment on lipopolysaccharide-induced testicular inflammation and reproductive hormone inhibition in adult rats, Journal of Endocrinology, vol 168, issue 1, Society for Endocrinology, Stokebristol England, pp. 193-201.

de Kretser, D.M., Loveland, K.A.L., Meehan, T.A., O'Bryan, M.K., Phillips, D.J., Wreford, N.G., 2001, Inhibins, activins and follistatin: actions on the testis, Molecular and Cellular Endocrinology, vol 180, Elsevier Ireland Ltd, Ireland, pp. 87-92.

Cram, D.S., O'Bryan, M., de Kretser, D.M., 2001, Male infertility genetics - The future, Journal of Andrology, vol 22, issue 5, American Society of Andrology, Lawrence Kansas USA, pp. 738-746.

Zini, A., O'Bryan, M.K., Schlegel, P.N., 2001, Nitric oxide synthase activity in human seminal plasma, Urology, vol 58, issue 1, Elsevier Science Ltd, New York, NY, USA, pp. 85-89.

Keah, H., O'Bryan, M., de Kretser, D.M., Hearn, M.T., 2001, Synthesis and application of peptide immunogens related to the sperm tail protein tpx-1, a member of the CRISP superfamily of proteins, Journal of Peptide Science, vol 57, John Wiley & Sons Ltd, West Sussex England, pp. 1-10.

O'Bryan, M., Sebire, K.L., Meinhardt, A., Edgar, K., Keah, H., Hearn, M.T., de Kretser, D.M., 2001, Tpx-1 is a component of the outer dense fibers and acrosome of rat spermatozoa, Molecular Reproduction and Development, vol 58, Wiley-Liss, New York NY USA, pp. 116-125.

O'Bryan, M.K., Schlatt, S., Phillips, D.J., de Kretser, D.M., Hedger, M., 2000, Bacterial lipopolysaccharide-induced inflammation compromises testicular function at multiple levels in vivo, Endocrinology, vol 141 issue 1, Endocrine Society, Bethesda USA, pp. 238-246.

O'Bryan, M.K., Sebire, K.L., Gerdprasert, O., Hedger, M., Hearn, M.T.W., de Kretser, D.M., 2000, Cloning and regulation of the rat activin betaE subunit, Journal of Molecular Endocrinology, vol 24, Society for Endocrinology, Bristol UK, pp. 409-418.

Buzzard, J.J., Morrison, J.R., O'Bryan, M.K., Song, Q., Wreford, N.G., 2000, Developmental expression of thyroid hormone receptors in the rat testis, Biology of Reproduction, vol 62, Society for the Study of Reproduction, Madison USA, pp. 664-669.

de Kretser, D.M., O'Bryan, M.K., Cram, D.S., McLachlan, R.I., 2000, Expanding our understanding of spermatogenesis: the future genetic tests for infertility, International Journal of Andrology, vol 23 supp 2, Blackwell Science Ltd, Oxford UK, pp. 30-33.

O'Bryan, M.K., Schlatt, S., Gerdprasert, O., Phillips, D.J., de Kretser, D.M., Hedger, M., 2000, Inducible nitric oxide synthase in the rat testis: Evidence for potential roles in both normal function and inflammation-mediated infertility, Biology of Reproduction, vol 63, Soc Study Reproduction, Madison USA, pp. 1285-1293.

Meehan, T., Schlatt, S., O'Bryan, M.K., de Kretser, D.M., Loveland, K.L., 2000, Regulation of germ cell and sertoli cell development by activin, follistatin, and FSH, Developmental Biology, vol 220, Academic Press Inc, San Diego USA, pp. 225-237.

de Kretser, D.M., Meinhardt, A., Meehan, T., Phillips, D.J., O'Bryan, M.K., Loveland, K.L., 2000, The roles of inhibin and related peptides in gonadal function, Molecular and Cellular Endocrinology, vol 161, Elsevier Science Ireland Ltd, Co Clare Ireland, pp. 43-46.

Meinhardt, A., Bacher, M., O'Bryan, M.K., McFarlane, J.R., Mallidis, C., Lehmann, C., Metz, C.N., de Kretser, D.M., Bucala, R., Hedger, M., 1999, A switch in the cellular localization of macrophage migration inhibitory factor in the rat testis after ethane dimethane sulfonate treatment, Journal of Cell Science, vol 112, Company of Biologists Ltd, Cambridge UK, pp. 1337-1344.

Kim, Y.H., McFarlane, J.R., O'Bryan, M.K., Almahbobi, G., Temple-Smith, P.D., de Kretser, D.M., 1999, Isolation and characterization of rat sperm tail outer dense fibres and comparison with rabbit and human spermatozoa using a polyclonal antiserum, Journal of Reproduction and Fertility, vol 116, Journals of Reproduction & Fertility Ltd, Cambridge UK, pp. 345-353.

Zini, A., O'Bryan, M.K., Israel, L., Schlegel, P.N., 1998, Human sperm NADH and NADPH diaphorase cytochemistry: correlation with sperm motility, UROLOGY, vol 51 (3), ELSEVIER SCIENCE INC, WWW.ELSEVIER.COM, pp. 464-468.

O'Bryan, M.K., Loveland, K.L., Herszfeld, D., McFarlane, J.R., Hearn, M.T., de Kretser, D.M., 1998, Identification of a rat testis-specific gene encoding a potential rat outer dense fibre protein, Molecular Reproduction and Development, vol 50, Wiley-Liss Inc, West Sussex UK, pp. 313-322.

O'Bryan, M.K., Loveland, K.L., Herszfeld, D., McFarlane, J.R., Hearn, M.T., de Kretser, D.M., 1998, Identification of a rat testis-specific gene encoding a potential rat outer dense fibre protein, MOLECULAR REPRODUCTION AND DEVELOPMENT, vol 50, WILEY-LISS, INC, New York NY USA, pp. 313-322.

Meinhardt, A., O'Bryan, M.K., McFarlane, J.R., Loveland, K.L., Mallidis, C., Foulds, L.M., Phillips, D.J., de Kretser, D.M., 1998, Localization of follistatin in the rat testis, Journal Of Reproduction And Fertility, vol 112, Journals of Reproduction and Fertility Ltd, CAMBRIDGE UK, pp. 233-241.

Thomas, T.J., Wang, H., Niclasen, P., O'Bryan, M.K., Evans, L.W., Groome, N.P., Pedersen, J., Risbridger, G.P., 1997, Expression and localization of activin subunits and follistatins in tissues from men with high grade prostate cancer, Journal of Clinical Endocrinology and Metabolism, vol 82, The Endocrine Society USA, Bethesda MD, pp. 3851-3858.

Conference Proceedings

O'Bryan, M.K., Borg, C.L., Jamsai, D., 2009, Mouse models as a tool to discover key regulators of male fertility, 9th International Congress of Andrology, 7-10 March 2009, MediMond International Proceedings, Italy, p. 57.

Gow, R.D., O'Bryan, M.K., Canny, B., Ooi, G.T., Hedger, M., 1999, Dexamethosone ameliorates the effects of lipopolysaccharide on systemic inflammation and hormone production in the rat but not local testicular inflammation, The Endocrine Society of Australia Proceedings 1999, Melbourne VIC 26-29 September 1999, Endocrine Society of Australia, Adelaide SA Australia, p. 158.

Meinhardt, A., Bacher, M., McFarlane, J.R., Metz, C.N., O'Bryan, M.K., de Kretser, D.M., Bucala, R., Hedger, M., 1998, Compensatory production of MIF in rat testis after EDS treatment, 10th European Workshop On Molecular And Cellular Endocrinology Of The Testis, CAPRI, ITALY 28.3.98, THE ARES-SERONO FOUNDATION, ROME ITALY, p. 23.

O'Bryan, M.K., Schlatt, S., Phillips, D.J., de Kretser, D.M., Hedger, M., 1998, Endotoxin-induced inflammation causes a biphasic inhibition of testicular function: possible roles for nitric oxide?, 10th European Workshop On Molecular And Cellular Endocrinology Of The Testis, CAPRI, ITALY 28.3.98, THE ARES-SERONO FOUNDATION, ROME ITALY, p. 10.

Hedger, M., Duckett, R., Gerdprasert, O., Meinhardt, A., O'Bryan, M.K., 1998, Immunology of the male reproductive tract, Proceedings Of The Aust Physiological & Pharmacological Society, BRISBANE - 27.9.98, ICMS AUSTRALASIA, Sydney NSW Australia, p. 402.

O'Bryan, M.K., Phillips, D.J., Schlatt, S., de Kretser, D.M., Hedger, M., 1998, Nitric oxide modulates steroidogenesis in the normal rat testis but is not the primary cause of reduced testosterone production during systemic inflammation, The Endocrine Society Of Australia Proceedings 1998 Volume 41, PERTH, 23.8.98, The Endocrine Society of Australia, Melbourne Vic Australia, p. 95.

O'Bryan, M.K., Hearn, M.T., de Kretser, D.M., 1998, Sperm tail genes and infertility, The Australian Society For Medical Research, HOBART, 22.11.98, LILLY AUSTRALIA, HTTP://WWW.LILLY.COM.AU, p. 39.

Keah, H., O'Bryan, M.K., de Kretser, D.M., Hearn, M.T., 1998, The use of synthetic peptides in the study of sperm tail development function, 3rd Australian Peptide Conference "From Discovery to Therapeutics", Laguna Quays The Whitsundays QLD Oct 4-9, 1998, Pink Panther Printing, Melbourne Vic Australia, p. 43.

O'Bryan, M.K., Keah, H., Hearn, M.T., de Kretser, D.M., 1998, Tpx-1 an outer dense fibre encoding gene in humans and rats, FSA'98 Program, Abstracts And Mini-Posters, HOBART, AUSTRALIA 28.10.98, The Fertility Society of Australia, Canberra ACT Australia, p. 25.

O'Bryan, M.K., Schlatt, S., Phillips, D.J., de Kretser, D.M., Hedger, M., 1997, Inhibition of testicular function during lipopolysaccharide-induced inflammation, The Endocrine Society of Australia - Proceedings, 28/9-2/10/97 Canberra, Endocrine Society of Australia, Prahran, p. 64.

de Kretser, D.M., Loveland, K.L., McFarlane, J.R., Meinhardt, A., O'Bryan, M.K., Simorangkir, D.R., Wreford, N.G., 1997, Paracrine interactions influencing germ cell development in the testis, The Endocrine Society Program and Abstracts, June 11-14 1997 Minnesota USA, The Endocrine Society Press, Bethesda USA, p. 54.

Gerdprasert, O., O'Bryan, M.K., Schlatt, S., Phillips, D.J., de Kretser, D.M., Hedger, M., 1997, Regulation of macrophages in the testis during endotoxin-induced imflammation, Australian Society for Medical Research Program and Abstracts, 23-26 November, Adelaide, Australian Society for Medical Research, Adelaide SA Australia, p. P23.B.

O'Bryan, M.K., 1997, Sperm tails and motility, Hormones & Men's Health Programme and Abstract Book, 19-21/3/97 Clayton, IRD & PHIMR, Clayton Vic Australia, p. 43.

Hedger, M., O'Bryan, M.K., Phillips, D.J., Schlatt, S., de Kretser, D.M., 1997, The effects of lipopolysaccharide on testicular androgen secretion are preceded by changes in the testicular vasculature, Journal of Reproductive Immunology, 30/9-3/10/97 Virginia, USA, Elsevier, New York NY USA, p. 35.

O'Bryan, M.K., Loveland, K.L., Herszfeld, D., McFarlane, J.R., Hearn, M.T., de Kretser, D.M., 1997, Tpx-1: A Rat Outer Dense Fibre Protein Gene, Aust Society for Reproductive Biology program and miniposters of abstracts, 29/9-1/10/97 Canberra, Vertebrate Biocontrol Cooperative Research Centre, Canberra ACT Australia, p. 27.

Grants

Title:

A new model of asthenospermia and a candidate gene for multiple ciliopathies.

Investigators:

O'Bryan, M, Ishikawa, T

Funding:

(2010 - 2013). National Health & Medical Research Council (NHMRC).

Title:

ABI 7400 ToF ToF mass spectrometer I.D. 264650.

Investigators:

Smith, A, Aguilar, M, Cooke, B, O'Bryan, M

Funding:

(2005 - 2009). National Health & Medical Research Council (NHMRC).

Title:

Aperio ScanScope AT (Digital slide scanner) with operating software and web-based SpectrumTM server license for an unlimited number of digital images.

Investigators:

O'Bryan, M, Furic, L, Risbridger, G, Bertram, J, Lieschke, G, Smyth, I, Watkins, D, Cole, T, McMenamin, P, Abud, H, Loveland, K

Funding:

(2012 - 2016). National Health & Medical Research Council (NHMRC).

Title:

Benign Prostatic Hyperplasia (BHP) and Male Fertility Control.

Investigators:

O'Bryan, M

Funding:

(2006 - 2010). Schering Aktiengesellschaft.

(2009 - 2013). Schering Aktiengesellschaft.

Title:

Cysteine rich secretory proteins (Crisp) are ion channel regulators with essential roles in male fertility.

Investigators:

O'Bryan, M, Gibbs, G

Funding:

(2007 - 2011). National Health & Medical Research Council (NHMRC).

(2009 - 2013). National Health & Medical Research Council (NHMRC).

Title:

Denaturing high pressure liquid chromatography (DHPLC) system.

Investigators:

de Kretser, D, O'Bryan, M, Cram, D, McLachlan, R, Clyne, C, Stanley, E, Fuller, P, Elefanty, A, Harley, V, Simpson, E, Perkins, A

Funding:

(2003 - 2007). National Health & Medical Research Council (NHMRC).

Title:

GGN as a regulator of DNA double strand break repair and genome integrity.

Investigators:

O'Bryan, M, Jamsai, D, Ormandy, C, Handel, M

Funding:

(2011 - 2015). Australian Research Council (ARC).

Title:

HEN1 is a regulator of piRNA metabolism, transcriptional regulation and mammalian male fertility.

Investigators:

O'Bryan, M, Adelson, D, Scott, H

Funding:

(2012 - 2016). Australian Research Council (ARC).

(2012 - 2016). Monash University.

Title:

High Performance Liquid Chromatography (hplc) System - Equipment Grant 2000.

Investigators:

de Kretser, D, Phillips, D, Hedger, M, Loveland, K, O'Bryan, M, Morrison, J, Risbridger, G, Pera, M, Hertzog, P

Funding:

(2000 - 2000). National Health & Medical Research Council (NHMRC).

Title:

Identification of genes essential for male fertility.

Investigators:

Gibbs, G, O'Bryan, M

Funding:

(2004 - 2008). Rebecca L. Cooper Medical Research Foundation Ltd.

Title:

Katanin p80 is a key regulator of microtubule dynamics and male fertility.

Investigators:

O'Bryan, M, O'Donnell, L, de Kretser, D

Funding:

(2012 - 2016). National Health & Medical Research Council (NHMRC).

Title:

Leica upgrade of multiphoton SPS TiSAF imaging system.

Investigators:

Harper, I, Marcelle, C, Lackmann, M, Bourne, J, Currie, P, McMenamin, P, Loveland, K, O'Bryan, M, Verkade, H, Bowman, J, Burke, R, Warr, C

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Title:

Leucine-rich guanylate kinase is a regulator of sperm tail development and motile cilia function.

Investigators:

O'Bryan, M, McLachlan, R, de Kretser, D

Funding:

(2013 - 2017). National Health & Medical Research Council (NHMRC).

Title:

NHMRC 1996 F/Ship - Dr M O'Bryan --- The expression and regulation of nitric oxide synthases in the male reproductive tract.

Investigators:

O'Bryan, M

Funding:

(2000 - ). National Health & Medical Research Council (NHMRC).

Title:

NHMRC Senior Research Fellowship - Level A . ID:384132.

Investigators:

O'Bryan, M

Funding:

(2006 - 2010). National Health & Medical Research Council (NHMRC).

(2009 - 2013). National Health & Medical Research Council (NHMRC).

Title:

Olympus MVX10 Macroview Microscope with DP72 digital camera andn imaging system.

Investigators:

Lieschke, G, O'Bryan, M, Loveland, K, Heng, J, McMenamin, P, Abud, H, Bourne, J, Verkade, H, Kaslin, V, Rosenthal, N

Funding:

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Title:

Seahorse XF24 Extracellular Flux Analyser.

Investigators:

Watt, M, Mitchell, C, Tiganis, T, Currie, P, Andrews, Z, Clarke, I, O'Bryan, M, Cowley, M, Sleeman, M, Dowling, D, Gabriel, K, Risbridger, G, Bruce, C, Brown, K, Johns, T, Sobey, C, Henry, B

Funding:

(2012 - 2016). National Health & Medical Research Council (NHMRC).

Title:

Studies on the genetic basis of male and idiopathic infertility and the trans-generational health of children conceived through ART.

Investigators:

O'Bryan, M

Funding:

(2010 - 2014). Monash IVF.

(2011 - 2016). Monash IVF.

(2012 - 2016). Monash IVF.

Title:

The Biology of Sperm Tail Development.

Investigators:

O'Bryan, M

Funding:

(2001 - 2004). National Health & Medical Research Council (NHMRC).

Title:

The Genetics of Male Infertility - Gene Discovery and Mutation Detection.

Investigators:

O'Bryan, M, de Kretser, D, Loveland, K

Funding:

(2001 - 2001). Rebecca L. Cooper Medical Research Foundation Ltd.

Title:

The expression and regulation of nitric oxide synthases in the male reproductive tract.

Investigators:

O'Bryan, M

Funding:

(1996 - 2000). Heart Foundation of Australia.

Title:

The function of gametogenetin in male fertility and embryogenesis.

Investigators:

O'Bryan, M, Jones, K

Funding:

(2008 - 2011). National Health & Medical Research Council (NHMRC).

(2008 - 2014). National Health & Medical Research Council (NHMRC).

(2009 - 2013). National Health & Medical Research Council (NHMRC).

Title:

The identification of male meiosis genes using a new mouse line and human genome scans for gene copy number variations.

Investigators:

O'Bryan, M

Funding:

(2008 - 2011). National Health & Medical Research Council (NHMRC).

(2009 - 2013). National Health & Medical Research Council (NHMRC).

Title:

Australian Centre for Vertebrate Mutation.

Investigators:

Hilton, D, Bertram, E, Currie, P, Forrest, S, Heath, J, Kile, B, Lieschke, G, O'Bryan, M

Funding:

(2007 - 2011). National Health & Medical Research Council (NHMRC).

(2009 - 2013). National Health & Medical Research Council (NHMRC).

(2011 - 2015). National Health & Medical Research Council (NHMRC).

Title:

Characterization of the molecular basis of human sperm-oocyte interaction.

Investigators:

O'Bryan, M, Nixon, B, McLaughlin, E

Funding:

(2009 - 2013). National Health & Medical Research Council (NHMRC).

Title:

NHMRC Australian Phenome Bank.

Investigators:

Goodnow, C, de Kretser, D, O'Bryan, M

Funding:

(2004 - 2008). National Health & Medical Research Council (NHMRC).

(2006 - 2010). National Health & Medical Research Council (NHMRC).

Title:

The role of importins in the control of spermatogenesis: (ARC Centre of Excellence in Biotechnology and Development).

Investigators:

Aitken, R, Jans, D, Loveland, K, Koopman, P, Sinclair, A, de Kretser, D, O'Bryan, M, Hime, G, Roman, S, McLaughlin, E, Goodnow, C, Holland, M

Funding:

(2003 - 2007). Australian Research Council (ARC).

(2009 - 2013). Australian Research Council (ARC).

Title:

Victorian node of the Australian Phenomics Network (APN-VIC).

Investigators:

O'Bryan, M, Hilton, D, Hertzog, P, Furness, J, Holland, M

Funding:

(2007 - 2011). Victorian Department of Innovation, Industry & Regional Development (DIIRD).

(2008 - 2012). Victorian Department of Innovation, Industry & Regional Development (DIIRD).

(2009 - 2013). Victorian Department of Innovation, Industry & Regional Development (DIIRD).

Title:

Cysteine-rich secretory protein regulation of ion channels in male fertility and prostate cancer.

Investigators:

O'Bryan, M, Gibbs, G, McIntyre, P

Funding:

(2010 - 2013). National Health & Medical Research Council (NHMRC).

(2010 - 2014). The University of Melbourne.

Title:

Control mechanisms of reproductive processes. ID: 334011.

Investigators:

de Kretser, D, Wallace, E, Risbridger, G, Hearn, M, Jenkin, G, Hedger, M, Loveland, K, Phillips, D, O'Bryan, M

Funding:

(2004 - 2008). National Health & Medical Research Council (NHMRC).

(2006 - 2010). National Health & Medical Research Council (NHMRC).

(2008 - 2012). National Health & Medical Research Council (NHMRC).

(2010 - 2014). National Health & Medical Research Council (NHMRC).

Postgraduate Research Supervisions

Completed Supervision

Student:

Cotton, L.

Program of Study:

FIBROBLAST GROWTH FACTOR RECEPTOR-1 (FGFR-1) IS ESSENTAL FOR SPERMIOGENESIS AND MALE FERTILITY. (PHD) 2005.

Supervisors:

De Kretser, D (Joint-Co), O''Bryan, M (Joint).

Student:

Gerdprasert, O.

Program of Study:

CELLULAR AND CYTOKINE RESPONSES TO INFLAMMATION IN THE RAT TESTIS. (PHD) 2002.

Supervisors:

De Kretser, D (Main), O''Bryan, M (Joint).

Student:

Hickox, D.

Program of Study:

CHARACTERISATION OF THE MOUSE TESTIS-SPECIFIC CYSTEINE-RICH SECRETORY PROTEIN TPX-1. (PHD) 2003.

Supervisors:

De Kretser, D (Main), O''Bryan, M (Associate).

Student:

Ip, C.

Program of Study:

The Role of Abca12 in Harlequin Ichthyosis.. (Masters) 2012.

Supervisors:

Smyth, I (Main), O''Bryan, M (Associate).

Student:

Kennedy, C.

Program of Study:

STUDIES TO IDENTIFY KEY MALE FERTILITY RELATED GENES USING ENU MUTAGENESIS. (PHD) 2005.

Supervisors:

De Kretser, D (Joint-Co), O''Bryan, M (Joint).

Student:

Reddy, T.

Program of Study:

The role of cysteine-rich secretory protein 4 in sperm function. (PHD) 2010.

Supervisors:

O''Bryan, M (Main).

Student:

Swain, L.

Program of Study:

THE DEVELOPMENT OF A MOUSE gDNA AND SPERM REPOSITORY FOR THE RAPID GENERATION OF GENETICALLY MODIFIED MOUSE LINES. (Masters) 2007.

Supervisors:

O''Bryan, M (Main), Jamsai, D (Associate).

Student:

Zamudio, N.

Program of Study:

Epigenetic regulation and male fertility. (PHD) 2009.

Supervisors:

O''Bryan, M (Main).