Dr Ruth Kennan - Researcher Profile

Biography

Ruth works in the Faculty of Medicine, Nursing & Health Sciences at Monash University as a Research Fellow.

Qualifications

DOCTOR OF PHILOSOPHY

Institution: La Trobe University

Year awarded: 1992

Publications

Book Chapters

Hampson, D.J., Nagaraja, T.G., Kennan, R.M., Rood, J.I., 2010, Gram-negative anaerobes, in Pathogenesis of Bacterial Infections in Animals, eds Carlton L. Gyles, John F. Prescott, J. Glenn Songer and Charles O. Thoen, Wiley-Blackwell, USA, pp. 513-526.

Journal Articles

Han, X.Y., Kennan, R.M., Steer, D.L., Smith, A.I., Whisstock, J.C., Rood, J.I., 2012, The AprV5 subtilase is required for the optimal processing of all three extracellular serine proteases from Dichelobacter nodosus, PLoS ONE [P], vol 7, issue 10 (Art. No.: e47932), Public Library of Science, USA, pp. 1-8.

Wong, W., Wijeyewickrema, L.C., Kennan, R.M., Reeve, S.B., Steer, D.L., Reboul, C., Smith, A.I., Pike, R.N., Rood, J.I., Whisstock, J.C., Porter, C.J., 2011, S1 pocket of a bacterially derived subtilisin-like protease underpins effective tissue destruction, Journal Of Biological Chemistry [P], vol 286, issue 49, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 42180-42187.

Kennan, R., Han, X., Porter, C., Rood, J., 2011, The pathogenesis of ovine footrot, Veterinary Microbiology [P], vol 153, issue 1-2, Elsevier Science BV, The Netherlands, pp. 59-66.

Wong, W., Kennan, R.M., Rosado, C.J., Rood, J.I., Whisstock, J., Porter, C.J., 2010, Crystallization of the virulent and benign subtilisin-like proteases from the ovine footrot pathogen Dichelobacter nodosus, Acta Crystallographica Section F: Structural Biology..., vol 66, issue 3, Wiley-Blackwell Publishing, Inc., US, UK, pp. 289-293.

Calvo-Bado, L.A., Green, L.E., Medley, G.F., Ul-Hassan, A., Grogono-Thomas, R., Buller, N., Kaler, J., Russell, C.L., Kennan, R.M., Rood, J.I., Wellington, E.M., 2010, Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus, Veterinary Microbiology [P], vol 147, issue 3-4, Elsevier BV, The Netherlands, pp. 358-366.

Kennan, R.M., Wong, W., Dhungyel, O., Han, X., Wong, D.M., Parker, D., Rosado, C.J., Law, R.H., McGowan, S., Reeve, S.B., Levina, V., Powers, G.A., Pike, R.N., Bottomley, S.P., Smith, A.I., Marsh, I., Whittington, R.J., Whisstock, J., Porter, C.J., Rood, J.I., 2010, The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates, Plos Pathogens [P], vol 6, issue 11, Public Library of Science, USA, pp. 1-12.

Cheetham, B.F., Parker, D., Bloomfield, G.A., Shaw, B.E., Sutherland, M., Hyman, J.A., Druitt, J., Kennan, R.M., Rood, J.I., Katz, M.E., 2008, Isolation of the bacteriophage DinoHI from Dichelobacter nodosus and its interactions with other integrated genetic elements, The Open Microbiology Journal, vol 2, Bentham Open, Netherlands, pp. 1-9.

Zhou, H., Bennett, G., Kennan, R.M., Rood, J.I., 2008, LETTER TO THE EDITOR: Identification of a leukotoxin sequence from Fusobacterium equinum, Veterinary Microbiology, vol E-Pub, Elsevier BV, The Netherlands, pp. 1-2.

Han, X.Y., Kennan, R.M., Davies, J.K., Reddacliff, L.A., Dhungyel, O.P., Whittington, R.J., Turnbull, L., Whitchurch, C.B., Rood, J.I., 2008, Twitching motility is essential for virulence in Dichelobacter nodosus, Journal of Bacteriology, vol 190, issue 9, American Society for Microbiology, United States, pp. 3323-3335.

Myers, G.S., Parker, D., Al-Hasani, K., Kennan, R.M., Seemann, T., Ren, Q., Badger, J.H., Selengut, J.D., DeBoy, R.T., Tettelin, H., Boyce, J.D., McCarl, V., Han, X.Y., Nelson, W.C., Madupu, R., Mohamoud, Y., Holley, T., Fedorova, N., Bottomley, S.P., Whittington, R.J., Adler, B., Songer, J., Rood, J.I., Paulsen, I.T., 2007, Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus, Nature Biotechnology, vol 25, issue 5, Nature Publishing Group, New York NY USA, pp. 569-575.

Han, X.Y., Kennan, R.M., Parker, D., Davies, J.K., Rood, J.I., 2007, Type IV fimbrial biogenesis is required for protease secretion and natural transformation in Dichelobacter nodosus, Journal of Bacteriology, vol 189, issue 14, American Society of Microbiology, Washington DC USA, pp. 5022-5033.

Parker, D., Kennan, R.M., Myers, G.S., Paulsen, I.T., Songer, J., Rood, J.I., 2006, Regulation of type IV fimbrial biogenesis in Dichelobacter nodosus, Journal of Bacteriology, vol 188, issue 13, Amer Soc Microbiology, USA, pp. 4801-4811.

Parker, D., Kennan, R.M., Myers, G.S., Paulsen, I.T., Rood, J.I., 2005, Identification of a Dichelobacter nodosus ferric uptake regulator and determination of its regulatory targets, Journal Of Bacteriology, vol 187, issue 1, American Society for Microbiology, USA, pp. 366-375.

Kennan, R.M., Dhungyel, O.P., Whittington, R.J., Egerton, J.R., Rood, J.I., 2003, Transformation-mediated serogroup conversion of Dichelobacter nodosus, Veterinary Microbiology, vol 92, issue 1-2, Elsevier BV, Amsterdam The Netherlands, pp. 169-178.

Kennan, R.M., Dhungyel, O.P., Whittington, R.J., Egerton, J.R., Rood, J.I., 2001, The type IV fimbrial subunit gene (fimA) of Dichelobacter nodosus is essential for virulence, protease secretion, and natural competence, Journal of Bacteriology, vol 183, issue 15, American Society for Microbiology, Washington DC USA, pp. 4451-4458.

Kennan, R.M., Billington, S.J., Rood, J.I., 1998, Electroporation - mediated transformation of the ovine footrot pathogen Dichelobacter nodosus, FEMS Microbiology Letters, vol 169, Elsevier Science BV, Amsterdam Netherlands, pp. 383-389.

Kennan, R.M., McMurray, L.M., Levy, S.B., Rood, J.I., 1997, Glutamate residues located within putative transmembrane helices are essential for TetA(P)-mediated tetracycline efflux, Journal of Bacteriology, vol 179, American Society for Microbiology, Washington DC, pp. 7011-7015.

Conference Proceedings

Kennan, R.M., Billington, S.J., Rood, J.I., 1998, Electroporation - mediated transformation of the ovine footrot pathogen Dichelobacter nodusus, Microbiology Australia, Hobart 27 September - 2 October 1998, Ink Press International, Subiaco WA Australia, p. P20.4.

Postgraduate Research Supervisions

Completed Supervision

Student:

Han, X.

Program of Study:

Type IV fimbrial biogenesis, protease secretion, natural transformation, and virulence of Dichelobacter nodosus. (PHD) 2007.

Supervisors:

Rood, J (Main), Davies, J (Associate), Kennan, R (Associate).

Student:

Parker, D.

Program of Study:

Regulation and genomics of Dichelobacter nodosus. (PHD) 2005.

Supervisors:

Rood, J (Main), Kennan, R (Associate).