Prof Ross Coppel - Researcher Profile
Address
Faculty of Medicine, Nursing & Health SciencesMonash University, Clayton
Contact Details
Email: Ross.Coppel@monash.edu
Biography
Higher duties still leave time for fundamental disease research
As Deputy Dean and Director of Research in the Faculty of Medicine, Nursing and Health Sciences, Professor Ross Coppel has many responsibilities. These include overseeing and maximising the quality and effectiveness of research in his faculty, ensuring that technological platforms are up-to-date and affordable, and supervising the faculty’s commercial and business development. Ross is also still exploring his research interests by studying two diseases that are responsible for around 10 per cent of the world’s deaths every year.
Malaria and tuberculosis germs are incredibly well-evolved to cause disease in many ways and have strong mechanisms to avoid the immune system. Ross says they also pose a huge challenge because therapies against them are becoming less effective. He is approaching them from different stages in the process.
“My tuberculosis research is aimed at understanding how the bacterium makes its cell wall,” he explains. “Tuberculosis bacteria have a different cell wall structure to other bacteria, and the cell wall stops it being killed by host cells as well as by many common antibiotics. Our research is based on the premise that if we understood how the unique components of the cell wall are put together, we could target them with new drugs. The research is around identifying those targets.
“In malaria, which again is largely treated with drugs, my interest has been more around vaccines. One of the problems, particularly in developing countries, is to have adequate drugs delivered in a timely manner to where the infections are occurring. We’ve done a lot of work over the years trying to develop malaria vaccines, and looking at how you might design and deliver them. We have an interest in understanding how the parasite works and causes disease, particularly when it lives inside the red cells,” he says.
Ross is also researching primary biliary cirrhosis (PBC), an uncommon autoimmune disease of the liver. While this disease only affects only a few thousand Australians at present, Ross thinks it offers some great lessons for diseases where the immune system turns against the body.
“With PBC, the immune system decides that part of the human body is foreign and makes an immune response. But strangely, although the component the immune system attacks exists in every single cell in the body, the damage occurs only to the cells that line the bile duct inside the liver. The immune system ignores all the other places this component exists in.
"We’ve actually worked out why this happens. All cells in the body undergo a process of replacement called apoptosis, or programmed cell death. The cells that line the bile ducts undergo their replacement in a different way, so the immune system sees the component as foreign and targets only those cells. In addition to this, people with PBC have the misfortune of some form of bacterial infection that has sensitised their immune system.”
Ross says this discovery may open doors to understanding immune responses against other organs.
“We’re hoping that what we’ve dissected in PBC can be applied to other disease research. We’re studying Sjogren's Syndrome, which targets the parotid gland, and we’d like to see if the immune system abnormalities we found with PBC exist in a different organ. Our past work has been in the group of diseases where the target is everywhere, but the damage is localised. We may also be able to look at diseases where the damage is everywhere, such as lupus, for example.”
Qualifications
- Unknown
- Institution: Australian Society of Microbiology
- Year awarded: 1996
- PHD
- Institution: University of Melbourne
- Year awarded: 1984
- DIPLOMA OF TROPICAL MEDICINE & HYGIENE
- Institution: The London School of Hygiene & Tropical Medicine
- Year awarded: 1979
- M.B.B.S SECOND CLASS HONOURS MED SURG OBS & GYNAE
- Institution: University of Melbourne
- Year awarded: 1976
- BACHELOR OF MEDICAL SCIENCE
- Institution: University of Melbourne
- Year awarded: 1974
Publications
Book Chapters
Zuerner, R., Bulach, D.M., Seemann, T., Coppel, R.L., Adler, B., 2006, Comparative analysis of pathogenic leptospira genomes, in Molecular Biology of Spirochetes, eds FC Cabello, D Hulinska and HP Godgrey, IOS Press, Amsterdam Netherlands, pp. 101-114.
Selmi, C., Coppel, R.L., Gershwin, M., 2006, Primary biliary cirrhosis, in The Autoimmune Diseases, eds Noel R. Rose, Ian R. Mackay, Elsevier, USA, pp. 749-765.
Topolska, A.E., Wang, L., Black, C.G., Coppel, R.L., 2004, Merozoite Cell Biology, in Malaria Parasites, eds A P Waters and C J Janse, Caister Academic Press, Norfolk England, pp. 365-444.
Cooke, B.M., Coppel, R.L., Nash, G.B., 2002, Analysis of the Adhesive Properties of Plasmodium Faciparum - infected red blood cells under conditions of flow, in Malaria Methods and Protocols, eds Denise L Doolan, Humana Press, Inc., Towota USA, pp. 561-569.
Menting, J.G.T., Coppel, R.L., 2002, Immunoprecipitation for Antigen Localization, in Malaria Methods and Protocols, eds Denise L Doolan, Humana Press Inc, Totowa USA, pp. 587-604.
Cooke, B.M., Coppel, R.L., Nash, G.B., 2002, Preparation of Adhesive Targets for Flow-Based Gytoadhesion Assays, in Malaria Methods and Protocols, eds Denis L Doolan, Humana Press Inc, Totowa USA, pp. 571-579.
Wang, L., Coppel, R.L., 2002, Triton x-114 Phase Partitioning for Antigen Characterization, in Malaria Methods and Protocols, eds Denise L Doolan, Humana Press Inc., Totowa USA, pp. 581-585.
Smith, K.A., Spithill, T.W., Coppel, R.L., 2001, Neural network classification of malaria protein sequences, in Intelligent Engineering Systems Through Artificial Neural Networks. Volume II - Smart Engineering System Design, eds Cihan H Dagli, Anna L Buczak, Joydeep Ghosh, Mark J Embrechts, Okan Ersoy and Stephen Kercel, ASME Press, New York NY USA, pp. 783-788.
Coppel, R.L., Black, C.G., 1998, Malaria parasite DNA, in Malaria. Parasite Biology, Pathogenesis, and Protection, ASM Press, Washington USA, pp. 185-202.
Leung, P.S., Manns, M.P., Coppel, R.L., Gershwin, M.E., 1997, Detection of antimitochondrial autoantibodies in primary biliary cirrhosis and liver-kidney microsomal antibodies in autoimmune hepatitis, in Manual of Clinical Laboratory Immunology, ASM Press, Washington DC, pp. 989-996.
Journal Articles
Tsuda, M., Zhang, W., Yang, G., Tsuneyama, K., Ando, Y., Kawata, K., Park, O., Leung, P.S., Coppel, R.L., Ansari, A.A., Ridgway, W.M., Gao, B., Lian, Z., Flavell, R.A., He, X., Gershwin, M.E., 2013, Deletion of IL-12p35 induces liver fibrosis in dominant negative transforming growth factor beta receptor type II mice, Hepatology [P], vol E-pub, John Wiley & Sons Inc, USA, pp. 1-36. View Publication
Al-deen, F.M.N., Ma, C.W.C., Xiang, S.D., Selomulya, C., Plebanski, M., Coppel, R.L., 2013, On the efficacy of malaria DNA vaccination with magnetic gene vectors, Journal of Controlled Release [P], vol 168, issue 1, Elsevier Science BV, Netherlands, pp. 10-17. View Publication
Jin, Q., Moritoki, Y., Lleo, A., Tsuneyama, K., Invernizzi, P., Moritoki, H., Kikuchi, K., Lian, Z., Hirschfield, G.M., Ansari, A.A., Coppel, R.L., Gershwin, M., Niu, J., 2012, Comparative analysis of portal cell infiltrates in antimitochondrial autoantibody-positive versus antimitochondrial autoantibody-negative primary biliary cirrhosis, Hepatology [P], vol 55, issue 5, John Wiley & Sons Inc, USA, pp. 1495-1506. View Publication
Yang, C., Leung, P.S., Yang, G., Kenny, T., Zhang, W., Coppel, R.L., Norman, G., Ansari, A.A., Mackay, I.R., Worman, H.J., Gershwin, M.E., 2012, Epitope-specific anti-nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine-dependent, Clinical And Experimental Immunology [P], vol 168, issue 3, Wiley-Blackwell Publishing Ltd, UK, pp. 261-267. View Publication
Nguyen, V., Chetty, M.R., Coppel, R.L., Wangikar, P.P., 2012, Gene regulatory network modeling via global optimization of high-order dynamic bayesian network, BMC Bioinformatics [P], vol 13, issue 131, BioMed Central Ltd., United Kingdom, pp. 1-16.
Nguyen, V., Chetty, M.R., Coppel, R.L., Wangikar, P.P., 2012, Gene regulatory network modeling via global optimization of high-order dynamic bayesian network, BMC Bioinformatics [P], vol 13, issue 131, BioMed Central Ltd, United Kingdom, pp. 1-16. View Publication
Pelosi, A., Smith, D.J., Brammananth, R., Topolska, A.E., Billman-Jacobe, H., Nagley, P., Crellin, P.K., Coppel, R.L., 2012, Identification of a novel gene product that promotes survival of mycobacterium smegmatis in macrophages, PLoS ONE [P], vol 7, issue 2 (e31788), Public Library of Science, USA, pp. 1-11. View Publication
Nguyen, V., Chetty, M.R., Coppel, R.L., Wangikar, P.P., 2012, Issues impacting genetic network reverse engineering algorithm validation using small networks, Biochimica et Biophysica Acta - Proteins and Proteomics [P], vol 1824, issue 12, Elsevier BV, Netherlands, pp. 1434-1441.
Ma, C.W.C., Wang, L., Webster, D.E., Campbell, A.E., Coppel, R.L., 2012, Production, characterisation and immunogenicity of a plant-made Plasmodium antigen - the 19 kDa C-terminal fragment of Plasmodium yoelii merozoite surface protein 1, Applied Microbiology And Biotechnology [P], vol 94, issue 1, Springer, Germany, pp. 151-161. View Publication
Zhang, J., Czabotar, P.E., Policheni, A.N., Caminschi, I., Wan, S., Kitsoulis, S., Tullett, K.M., Robin, A.Y., Brammananth, R., van Delft, M.F., Lu, J., O'Reilly, L.A., Josefsson, E.C., Kile, B.T., Chin, W., Mintern, J.D., Olshina, M.A., Wong, W., Baum, J., Wright, M.D., Huang, D.C., Mohandas, N., Coppel, R.L., Colman, P.M., Nicola, N.A., Shortman, K., Lahoud, M.H., 2012, The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments, Immunity [P], vol 36, issue 4, Cell Press, USA, pp. 646-657. View Publication
Ando, Y., Yang, G., Tsuda, M., Kawata, K., Zhang, W., Nakajima, T., Tsuneyama, K., Leung, P.S., Lian, Z., Okazaki, K., Ridgway, W.M., Norman, G.L., Ansari, A.A., He, X., Coppel, R.L., Gershwin, M.E., 2012, The immunobiology of colitis and cholangitis in IL-23p19 and IL-17A deleted dominant negative form of transforming growth factor beta receptor type II mice, Hepatology [P], vol 56, issue 4, John Wiley & Sons Inc, USA, pp. 1418-1426. View Publication
Rainczuk, A.K., Yamaryo-Botte, Y., Brammananth, R., Stinear, T.P., Seemann, T., Coppel, R.L., McConville, M.J., Crellin, P.K., 2012, The lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria, Journal Of Biological Chemistry [P], vol 287, issue 51, American Society for Biochemistry and Molecular Biology Inc., USA, pp. 42726-42738. View Publication
Dhirapong, A., Lleo, A., Yang, G., Tsuneyama, K., Dunn, R., Kehry, M., Packard, T.A., Cambier, J.C., Liu, F., Lindor, K., Coppel, R.L., Ansari, A.A., Gershwin, M.E., 2011, B cell depletion therapy exacerbates murine primary biliary cirrhosis, Hepatology [P], vol 53, issue 2, John Wiley & Sons, Inc., USA, pp. 527-535. View Publication
Crellin, P.K., Brammananth, R., Coppel, R.L., 2011, Decaprenylphosphoryl-beta-D-ribose 2'-epimerase, the target of benzothiazinones and dinitrobenzamides, is an essential enzyme in Mycobacterium smegmatis, PLoS ONE [P], vol 6, issue 2 (Art. No: e16869), Public Library of Science, USA, pp. 1-8. View Publication
Salwati, E., Minigo, G., Woodberry, T., Piera, K., De Silva, H., Kenangalem, E., Tjitra, E., Coppel, R., Price, R., Anstey, N., Plebanski, M., 2011, Differential cellular recognition of antigens during acute Plasmodium falciparum and Plasmodium vivax malaria, Journal Of Infectious Diseases [P], vol 203, issue 8, Oxford University Press, USA, pp. 1192-1199. View Publication
Naiyanetr, P., Butler, J., Meng, L., Pfeiff, J., Kenny, T., Guggenheim, K., Reiger, R., Lam, K., Kurth, M., Ansari, A., Coppel, R., Lopez-Hoyos, M., Gershwin, M., Leung, P., 2011, Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity, Journal Of Autoimmunity [P], vol 37, issue 3, Academic Press, UK, pp. 209-216. View Publication
Rong, G., Zhong, R., Lleo, A., Leung, P., Bowlus, C., Yang, G., Yang, C., Coppel, R., Ansari, A., Cuebas, D., Worman, H., Invernizzi, P., Gores, G., Norman, G., He, X., Gershwin, M., 2011, Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis, Hepatology [P], vol 54, issue 1, John Wiley & Sons, Inc., USA, pp. 196-203. View Publication
Tsuda, M., Ambrosini, Y., Zhang, W., Yang, G., Ando, Y., Rong, G., Tsuneyama, K., Sumida, K., Shimoda, S., Bowlus, C., Leung, P., He, X., Coppel, R., Ansari, A., Lian, Z., Gershwin, M., 2011, Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis, Hepatology [P], vol 54, issue 4, John Wiley & Sons, Inc., USA, pp. 1293-1302. View Publication
Nguyen, V., Chetty, M., Coppel, R., Wangikar, P., 2011, GlobalMIT: learning globally optimal dynamic Bayesian network with the mutual information test criterion, Bioinformatics [P], vol 27, issue 19, Oxford University Press, Oxford England, pp. 2765-2766. View Publication
Botte, C., Yamaryo-Botte, Y., Janouskovec, J., Rupasinghe, T., Keeling, P., Crellin, P., Coppel, R., Marechal, E., McConville, M., McFadden, G., 2011, Identification of plant-like galactolipids in Chromera velia, a photosynthetic relative of malaria parasites, Journal Of Biological Chemistry [P], vol 286, issue 34, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 29893-29903. View Publication
Selmi, C., Bowlus, C., Gershwin, M., Coppel, R., 2011, Primary biliary cirrhosis, Lancet [P], vol 377, issue 9777, The Lancet Publishing Group, UK, pp. 1600-1609. View Publication
Al-deen, F., Ho, J., Selomulya, C., Ma, C., Coppel, R., 2011, Superparamagnetic nanoparticles for effective delivery of malaria DNA vaccine, Langmuir [P], vol 27, issue 7, American Chemical Society, USA, pp. 3703-3712. View Publication
De Silva, H.D., Saleh, S.M., Kovacevic, S., Wang, L., Black, C.G., Plebanski, M., Coppel, R.L., 2011, The antibody response to Plasmodium falciparum Merozoite Surface Protein 4: Comparative assessment of specificity and growth inhibitory antibody activity to infection-acquired and immunization-induced epitopes, Malaria Journal [P], vol 10, issue Art. No: 266, BioMed Central Ltd, UK, pp. 1-12. View Publication
Ambrosini, Y.M., Yang, G., Zhang, W., Tsuda, M., Shu, S., Tsuneyama, K., Leung, P.S., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 2011, The multi-hit hypothesis of primary biliary cirrhosis: Polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis, Clinical And Experimental Immunology [P], vol 166, issue 1, Wiley-Blackwell Publishing Ltd, UK, pp. 110-120. View Publication
Wang, L., Ma, C.W.C., Coppel, R.L., 2010, Alternative approaches to vaccine delivery, Human Vaccines [P], vol 6, issue 1, Landes Bioscience, USA, pp. 133-138. View Publication
Logan, G.J., Wang, L., Zheng, M., Coppel, R.L., Alexander, I.E., 2010, Antigen fusion with C3d3 augments or inhibits humoral immunity to AAV genetic vaccines in a transgene-dependent manner, Immunology And Cell Biology [P], vol 88, Nature Publishing Group, UK , Australia, pp. 228-232. View Publication
Ma, C., Harrison, P.F., Wang, L., Coppel, R.L., 2010, Automated estimation of parasitaemia of Plasmodium yoelii-infected mice by digital image analysis of Giemsa-stained thin blood smears, Malaria Journal [P], vol 9, issue Art. No: 348, BioMed Central Ltd, UK, pp. 1-9. View Publication
Lleo, A., Bowlus, C., Yang, G., Invernizzi, P.L., Podda, M., Van De Water, J., Ansari, A.A., Coppel, R.L., Worman, H.J., Gores, G.J., Gershwin, M., 2010, Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis, Hepatology [P], vol 52, issue 3, John Wiley & Sons, Inc., USA, pp. 987-996. View Publication
Scoble, J.A., McAlister, A.D., Fulton, Z.J., Troy, S.T., Byres, E., Vivian, J., Brammananth, R., Wilce, M.C.J., Le Nours, J., Zaker-Tabrizi, L., Coppel, R.L., Crellin, P., Rossjohn, J., Beddoe, T.C., 2010, Crystal structure and comparative functional analyses of a Mycobacterium aldo-keto reductase, Journal of Molecular Biology [P], vol 398, issue 1, Academic Press, UK, pp. 26-39. View Publication
Zhang, W., Tsuda, M., Yang, G., Tsuneyama, K., Rong, G., Ridgway, W.M., Ansari, A.A., Flavell, R.A., Coppel, R.L., Lian, Z., Gershwin, M., 2010, Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis, Hepatology [P], vol 52, issue 1, John Wiley & Sons, Inc., USA, pp. 215-222. View Publication
Proellocks, N.I., Coppel, R.L., Waller, K.L., 2010, Dissecting the apicomplexan rhoptry neck proteins, Trends in Parasitology [P], vol 26, issue 6, Elsevier Ltd, UK, pp. 297-304. View Publication
Murhandarwati, E.E.H., Wang, L., De Silva, H.D., Ma, C.W.C., Plebanski, M., Black, C.G., Coppel, R.L., 2010, Growth-inhibitory antibodies are not necessary for protective immunity to malaria infection, Infection And Immunity [P], vol 78, American Society for Microbiology, USA, pp. 680-687. View Publication
Waller, K.L., Stubberfield, L.M., Dubljevic, V., Buckingham, D.W., Mohandas, N., Coppel, R.L., Cooke, B.M., 2010, Interaction of the exported malaria protein Pf332 with the red blood cell membrane skeleton, Biochimica et Biophysica Acta - Biomembranes [P], vol 1798, issue 5, Elsevier BV, The Netherlands, pp. 861-871. View Publication
Liu, S., Danquah, M.K., Forde, G., Ma, C.W.C., Wang, L., Coppel, R.L., 2010, Microparticle-mediated gene delivery for the enhanced expression of a 19-kDa fragment of merozoite surface protein 1 of Plasmodium falciparum, Biotechnology Progress [P], vol 26, Wiley-Blackwell Publishing, Inc., USA, pp. 257-262.
Morita, Y.S., Yamaryo, Y., Miyanagi, K., Callaghan, J.M., Patterson, J.H., Crellin, P., Coppel, R.L., Billman-Jacobe, H., Kinoshita, T., McConville, M.J., 2010, Stress-induced synthesis of phosphatidylinositol 3-phosphate in mycobacteria, Journal Of Biological Chemistry [P], vol 285, issue 22, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 16643-16650. View Publication
Crellin, P., Vivian, J., Scoble, J.A., Chow, F.M., West, N.P., Brammananth, R., Proellocks, N.I., Shahine, A.E., Le Nours, J., Wilce, M.C., Britton, W.J., Coppel, R.L., Rossjohn, J., Beddoe, T.C., 2010, Tetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viability, Journal Of Biological Chemistry [P], vol 285, issue 39, American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 30050-30060. View Publication
Bracho, G., Zayas, C., Wang, L., Coppel, R.L., Perez, O., Petrovsky, N., 2009, AFCo1, a meningococcal B-derived cochleate adjuvant, strongly enhances antibody and T-cell immunity against Plasmodium falciparum merozoite surface protein 4 and 5, Malaria Journal, vol 8, issue 35, BioMed Central Ltd., UK, pp. 1-10. View Publication
Logan, G.J., Wang, L., Zheng, M., Ginn, S.L., Coppel, R.L., Alexander, I.E., 2009, Antigen-specific humoral tolerance or immune augmentation induced by intramuscular delivery of adeno-associated viruses encoding CTLA4-Ig-antigen fusion molecules, Gene Therapy, vol 16, issue 2, Nature Publishing Group, UK, pp. 200-210. View Publication
Lleo, A., Selmi, C., Invernizzi, P., Podda, M., Coppel, R.L., Mackay, I.R., Gores, G.J., Ansari, A.A., Van De Water, J., Gershwin, M., 2009, Apotopes and the biliary specificity of primary biliary cirrhosis, Hepatology, vol 49, issue 3, John Wiley & Sons, Inc., USA, pp. 871-879. View Publication
Moritoki, Y., Zhang, W., Tsuneyama, K., Yoshida, K., Wakabayashi, K., Yang, G., Bowlus, C., Ridgway, W.M., Ueno, Y., Ansari, A.A., Coppel, R.L., Mackay, I.R., Flavell, R.A., Gershwin, M., Lian, Z., 2009, B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis, Gastroenterology, vol 136, issue 3, WB Saunders Co., USA, pp. 1037-1047. View Publication
Moritoki, Y., Lian, Z., Lindor, K., Tuscano, J., Tsuneyama, K., Zhang, W., Ueno, Y., Dunn, R., Kehry, M., Coppel, R.L., Mackay, I.R., Gershwin, M., 2009, B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice, Hepatology [P], vol 50, issue 6, John Wiley & Sons, Inc., USA, pp. 1893-1903. View Publication
Proellocks, N.I., Kats, L.M., Sheffield, D.A., Hanssen, E., Black, C.G., Waller, K.L., Coppel, R.L., 2009, Characterisation of PfRON6, a Plasmodium falciparum rhoptry neck protein with a novel cysteine-rich domain, International Journal for Parasitology, vol 39, issue 6, Elsevier Ltd, UK, pp. 683-692. View Publication
Yoshida, K., Yang, G., Zhang, W., Tsuda, M., Tsuneyama, K., Moritoki, Y., Ansari, A.A., Okazaki, K., Lian, Z., Coppel, R.L., Mackay, I.R., Gershwin, M., 2009, Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice, Hepatology [P], vol 50, issue 5, John Wiley & Sons, Inc., USA, pp. 1494-1500. View Publication
Hsu, W., Zhang, W., Tsuneyama, K., Moritoki, Y., Ridgway, W.M., Ansari, A.A., Coppel, R.L., Lian, Z., Mackay, I.R., Gershwin, M., 2009, Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha-/- mice, Hepatology, vol 49, John Wiley & Sons, Inc., United States, pp. 133-140. View Publication
Stewart, V.A., Coppel, R.L., 2009, EDITORIAL: Issues in malaria vaccine development, Parasite Immunology [P], vol 31, issue 9, Wiley-Blackwell Publishing Ltd, UK, pp. 489-491. View Publication
Glenister, F.K., Fernandez, K.M., Kats, L.M., Hanssen, E., Mohandas, N., Coppel, R.L., Cooke, B.M., 2009, Functional alteration of red blood cells by a megadalton protein of Plasmodium falciparum, Blood, vol 113, issue 4, American Society of Hematology, USA, pp. 919-928. View Publication
Lan, R.Y., Salunga, T.L., Tsuneyama, K., Lian, Z., Yang, G., Hsu, W., Moritoki, Y., Ansari, A.A., Kemper, C., Price, J., Atkinson, J.P., Coppel, R.L., Gershwin, M., 2009, Hepatic IL-17 responses in human and murine primary biliary cirrhosis, Journal of Autoimmunity, vol 32, Academic Press, United Kingdom, pp. 43-51. View Publication
Sehgal, M.B., Gondal, I., Dooley, L.S., Coppel, R.L., 2009, How to improve postgenomic knowledge discovery using imputation, Eurasip Journal on Bioinformatics and Systems Biology [P], vol 2009, Hindawi Publishing Corporation, New York NY USA, pp. 1-14.
Richard, D., Kats, L.M., Langer, C., Black, C.G., Mitri, K., Boddey, J.A., Cowman, A.F., Coppel, R.L., 2009, Identification of rhoptry trafficking determinants and evidence for a novel sorting mechanism in the malaria parasite Plasmodium falciparum, PL o S Pathogens, vol 5, issue 3 (e1000328), Public Library of Science, USA, pp. 1-13. View Publication
Wakabayashi, K., Yoshida, K., Leung, P.S.C., Moritoki, Y., Yang, G., Tsuneyama, K., Lian, Z., Hibi, T., Ansari, A.A., Wicker, L.S., Ridgway, W.M., Coppel, R.L., Mackay, I.R., Gershwin, M., 2009, Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization, Clinical and Experimental Immunology, vol 155, Wiley-Blackwell Publishing Ltd., UK, pp. 577-586. View Publication
Murhandarwati, E.E.H., Wang, L., Black, C.G., Nhan, D.H., Richie, T.L., Coppel, R.L., 2009, Inhibitory antibodies specific for the 19-kilodalton fragment of merozoite surface protein 1 do not correlate with delayed appearance of infection with Plasmodium falciparum in semi-immune individuals in Vietnam, Infection And Immunity [P], vol 77, issue 10, American Society for Microbiology, USA, pp. 4510-4517. View Publication
Morahan, B.J., Wang, L., Coppel, R.L., 2009, No TRAP, no invasion, Trends in Parasitology, vol 25, Elsevier Ltd., United Kingdom, pp. 77-84. View Publication
Liu, S., Danquah, M.K., Ho, J., Ma, C.W.C., Wang, L., Coppel, R.L., Forde, G., 2009, Preparation and characterization of poly(lactic-co-glycolic acid) microparticles containing DNA molecules encoding a malaria vaccine candidate, Journal of Chemical Technology and Biotechnology [P], vol 84, issue 5, John Wiley & Sons Ltd, England, pp. 782-788. View Publication
Padgett, K.A., Lan, R.Y., Leung, P.C., Lleo, A., Dawson, K., Pfeiff, J., Mao, T.K., Coppel, R.L., Ansari, A.A., Gershwin, M., 2009, Primary biliary cirrhosis is associated with altered hepatic microRNA expression, Journal of Autoimmunity, vol 32, issue 3-4, Academic Press, UK, pp. 246-253. View Publication
Webster, D.E., Wang, L., Mulcair, M., Ma, C., Santi, L., Mason, H., Wesselingh, S.L., Coppel, R.L., 2009, Production and characterization of an orally immunogenic Plasmodium antigen in plants using a virus-based expression system, Plant Biotechnology Journal [P], vol 7, Blackwell Publishing Ltd, USA, pp. 846-855. View Publication
Coppel, R.L., 2009, Vaccinating with the genome: a Sisyphean task?, Trends in Parasitology, vol 25, issue 5, Elsevier Ltd, UK, pp. 205-212. View Publication
Murhandarwati, E.E.H., Black, C.G., Wang, L., Weisman, S., de Koning-Ward, T.F., Baird, J.K., Tjitra, E., Richie, T.L., Crabb, B.S., Coppel, R.L., 2008, Acquisition of invasion-inhibitory antibodies specific for the 19-kDa fragment of merozoite surface protein 1 in a transmigrant population requires multiple infections, The Journal of Infectious Diseases, vol 198, issue 8, University of Chicago Press, USA, pp. 1212-1218. View Publication
Kats, L., Wang, L., Murhandarwati, E.E.H., Mitri, K., Black, C.G., Coppel, R.L., 2008, Active immunisation with RAMA does not provide protective immunity against Plasmodium yoelii challenge despite its association with protective responses in endemic populations, Vaccine, vol 26, issue 26, Elsevier Ltd., United Kingdom, pp. 3261-3267. View Publication
Yang, G., Lian, Z., Chuang, Y., Moritoki, Y., Lan, R.Y., Wakabayashi, K., Ansari, A.A., Flavell, R.A., Ridgway, W.M., Coppel, R.L., Tsuneyama, K., Mackay, I.R., Gershwin, M., 2008, Adoptive transfer of CD8+ T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice, Hepatology, vol 47, issue 6, John Wiley & Sons, Inc., United States, pp. 1974-1982. View Publication
Sehgal, S.B., Gondal, I., Dooley, L.S., Coppel, R.L., 2008, Ameliorative missing value imputation for robust biological knowledge inference, Journal of Biomedical Informatics, vol 41, Academic Press, United States, pp. 499-514.
Lea-Smith, D.J., Martin, K., Pyke, J.S., Tull, D., McConville, M.J., Coppel, R.L., Crellin, P., 2008, Analysis of a new mannosyltransferase required for the synthesis of phosphatidylinositol mannosides and lipoarbinomannan reveals two lipomannan pools in corynebacterineae, Journal of Biological Chemistry, vol 283, issue 11, American Society for Biochemistry and Molecular Biology, Inc., United States, pp. 6773-6782. View Publication
Woodberry, T., Minigo, G., Piera, K.A., Hanley, J., De Silva, H.D., Salwati, E., Kenangalem, E., Tjitra, E., Coppel, R.L., Price, R.N., Anstey, N.M., Plebanski, M., 2008, Antibodies to Plasmodium falciparum and Plasmodium vivax merozoite surface protein 5 in Indonesia: Species-specific and cross-reactive responses, Thr Journal of Infectious Diseases, vol 198, issue 1, University of Chisago Press, United States, pp. 134-142. View Publication
Fulton, Z.J., McAlister, A.D., Wilce, M.C., Brammananth, R., Zaker-Tabrizi, L., Perugini, M.A., Bottomley, S.P., Coppel, R.L., Crellin, P., Rossjohn, J., Beddoe, T.C., 2008, Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species, Journal of Biological Chemistry, vol 283, issue 41, American Society for Biochemistry and Molecular Biology, Inc., United States, pp. 27881-27890. View Publication
Maier, A.G., Rug, M., O'Neill, M.T., Brown, M., Srabasti, S., Szestak, T., Chesson, J., Wu, Y., Hughes, K., Coppel, R.L., Newbold, C., Beeson, J.G., Craig, A., Crabb, B.S., Cowman, A.F., 2008, Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes, Cell, vol 134, issue 1, Cell Press, United States, pp. 48-61. View Publication
Fulton, Z.J., Crellin, P., Brammananth, R., Zaker-Tabrizi, L., Coppel, R.L., Rossjohn, J., Beddoe, T.C., 2008, Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria, Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, vol 64, issue Pt 5, Wiley-Blackwell Munksgaard, Denmark, pp. 428-431. View Publication
Picardeau, M., Bulach, D.M., Bouchier, C., Zuerner, R.L., Zidane, N., Wilson, P., Creno, S., Kuczek, E., Bommezzadri, S., Davis, J., McGrath, A., Johnson, M., Boursaux-Eude, C., Seemann, T., Rouy, Z., Coppel, R.L., Rood, J.I., Lajus, A., Davies, J.K., Medigue, C., Adler, B., 2008, Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis, PL o S One, vol 3, issue 2 (e1607), Public Library of Science, USA, pp. 1-9. View Publication
Von Itzstein, M., Plebanski, M., Cooke, B.M., Coppel, R.L., 2008, Hot, sweet and sticky: The glycobiology of Plasmodium falciparum, Trends in Parasitology, vol 24, issue 5, Elsevier Ltd., Trends Journals, United Kingdom, pp. 210-218. View Publication
Wang, L., Webster, D., Campbell, A.E., Dry, I.B., Wesselingh, S.L., Coppel, R.L., 2008, Immunogenicity of Plasmodium yoelii merozoite surface protein 4/5 produced in transgenic plants, International Journal of Parasitology, vol 38, Pergamon-Elsevier Science Ltd, Oxford England UK, pp. 103-110. View Publication
Oertelt-Prigione, S., Mao, T.K., Selmi, C., Tsuneyama, K., Ansari, A.A., Coppel, R.L., Invernizzi, P., Podda, M., Gershwin, M., 2008, Impaired indoleamine 2,3-dioxygenase production contributes to the development of autoimmunity in primary biliary cirrhosis, Autoimmunity, vol 41, issue 1, Informa Healthcare, United Kingdom, pp. 92-99. View Publication
Black, C.G., Proellocks, N.I., Kats, L., Cooke, B.M., Mohandas, N., Coppel, R.L., 2008, In vivo studies support the role of trafficking and cytoskeletal-binding motifs in the interaction of MESA with the membrane skeleton of Plasmodium falciparum-infected red blood cells, Molecular and Biochemical Parasitology, vol 160, issue 2, Elsevier BV, Netherlands, pp. 143-147. View Publication
Wakabayashi, K., Lian, Z., Leung, P.S.C., Moritoki, Y., Tsuneyama, K., Kurth, M.J., Lam, K.S., Yoshida, K., Yang, G., Hibi, T., Ansari, A.A., Ridgway, W.M., Coppel, R.L., Mackay, I.R., Gershwin, M., 2008, Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease, Hepatology, vol 48, issue 2, John Wiley & Sons, Inc., United States, pp. 531-540. View Publication
Plebanski, M., Locke, E., Kazura, J.W., Coppel, R.L., 2008, Malaria vaccines: into a mirror, darkly?, Trends in Parasitology, vol 24, issue 12, Elsevier Ltd., Trends Journals, United Kingdom, pp. 532-536. View Publication
Crellin, P., Kovacevic, S., Martin, K.L., Brammananth, R., Morita, Y.S., Billman-Jacobe, H., McConville, M.J., Coppel, R.L., 2008, Mutations in pimE restore lipoarabinomannan synthesis and growth in a Mycobacterium smegmatis lpqW mutant, Journal of Bacteriology, vol 190, issue 10, American Society for Microbiology, USA, pp. 3690-3699. View Publication
Wang, L., Coppel, R.L., 2008, Oral vaccine delivery: can it protect against non-mucosal pathogens?, Expert Review of Vaccines, vol 7, issue 6, Expert Reviews Ltd., United Kingdom, pp. 729-738. View Publication
Kats, L., Cooke, B.M., Coppel, R.L., Black, C.G., 2008, Protein trafficking to apical organelles of malaria parasites - building an invasion machine, Traffic, vol 9, Blackwell Publishing, Oxford, England, UK, pp. 176-186. View Publication
Danquah, M.K., Liu, S., Ho, J., Wang, L., Coppel, R.L., Forde, G., 2008, Rapid production of a plasmid DNA encoding a malaria vaccine candidate via amino-functionalized poly(GMA-co-EDMA) monolith, AIChE Journal, vol 54, issue 11, Wiley, USA, pp. 2990-2998.
Oertelt, S., Rieger, r., Selmi, C., Invernizzi, P., Ansari, A.A., Coppel, R.L., Podda, M., Leung, P.S.C., Gershwin, M., 2007, A sensitive bead assay for antimitochondrial antibodies: Chipping away at AMA-negative primary biliary cirrhosis, Hepatology, vol 45, issue 3, John Wiley & Sons Inc, Hoboken NJ USA, pp. 659-665. View Publication
Logan, G.J., Wang, L., Zheng, M., Cunningham, S.C., Coppel, R.L., Alexander, I.E., 2007, AAV vectors encoding malarial antigens stimulate antigen-specific immunity but do not protect from parasite infection, Vaccine, vol 25, Elsevier Ltd, UK, pp. 1014-1022.
Moritoki, Y., Lian, Z., Wulff, H., Yang, G., Chuang, Y., Lan, R.Y., Ueno, Y., Ansari, A.A., Coppel, R.L., Mackay, I.R., Gershwin, M., 2007, AMA production in primary biliary cirrhosis is promoted by the TLR9 ligand CpG and suppressed by potassium channel blockers, Hepatology, vol 45, issue 2, John Wiley & Sons Inc, Hoboken NJ USA, pp. 314-322. View Publication
Eisen, D.P., Wang, L., Jouin, H., Murhandarwati, E.E.H., Black, C.G., Mercereau-Puijalon, O., Coppel, R.L., 2007, Antibodies elicited in adults by a primary Plasmodium falciparum blood-stage infection recognize different epitopes compared with immune individuals, Malaria Journal, vol 6, issue 86, Biomed Central Ltd, London England UK, pp. 1-9. View Publication
Lleo, A., Invernizzi, P., Selmi, C., Coppel, R.L., Alpini, G., Podda, M., Mackay, I.R., Gershwin, M., 2007, Autophagy: highlighting a novel player in the autoimmunity scenario, Journal of Autoimmunity, vol 29, issue 2-3, Academic Press Ltd Elsevier Science Ltd, London, England, UK, pp. 61-68. View Publication
Leung, P.S., Park, O., Tsuneyama, K., Kurth, M.J., Lam, K.S., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 2007, Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic Immunization, Journal of Immunology, vol 179, issue 4, American Association of Immunologists, Bethesda MD USA, pp. 2651-2657. View Publication
Waller, K.L., Stubberfield, L.M., Dubljevic, V., Nunomura, W., An, X., Mason, A.J., Mohandas, N., Cooke, B.M., Coppel, R.L., 2007, Interactions of Plasmodium falciparum erythrocyte membrane protein 3 with the red blood cell membrane skeleton, Biochimica et Biophysica ACTA-Biomembranes, vol 1768, issue 9, Elsevier Science BV, Amsterdam Netherlands, pp. 2145-2156. View Publication
Oertelt, S., Ridgway, W.M., Ansari, A.A., Coppel, R.L., Gershwin, M., 2007, Murine models of primary biliary cirrhosis: Comparisons and contrasts, Hepatology Research, vol 37, issue Suppl 3, Blackwell Publishing, Oxford, England, UK, pp. S365-S369. View Publication
Proellocks, N.I., Kovacevic, S., Ferguson, D.J., Kats, L., Morahan, B.J., Black, C.G., Waller, K.L., Coppel, R.L., 2007, Plasmodium falciparum Pf34, a novel GPI-anchored rhoptry protein found in detergent-resistant microdomains, International Journal for Parasitology, vol 37, issue 11, Pergamon-Elsevier Science Ltd, Oxford England UK, pp. 1233-1241. View Publication
Pei, X., Guo, X., Coppel, R.L., Mohandas, N., An, X., 2007, Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) destabilizes erythrocyte membrane skeleton, Journal of Biological Chemistry, vol 282, issue 37, American Society of Biochemistry & Molecular Biology Inc, Bethesda MD USA, pp. 26754-26758. View Publication
Davis, C.B., Hartnell, R.D., Madge, P.D., Owen, D.J., Thomson, R.J., Chong, A.K., Coppel, R.L., Von Itzstein, M., 2007, Synthesis and biological evaluation of galactofuranosyl alkyl thioglycosides as inhibitors of mycobacteria, Carbohydrate Research, vol 342, issue 12-13, Elsevier Sci Ltd, Oxford England UK, pp. 1773-1780. View Publication
Owen, D.J., Davis, C.B., Hartnell, R.D., Madge, P.D., Thomson, R.J., Chong, A.K.J., Coppel, R.L., Von Itzstein, M., 2007, Synthesis and evaluation of galactofuranosyl N,N-dialkyl sulfenamides and sulfonamides as antimycobacterial agents, Bioorganic & Medicinal Chemistry Letters, vol 17, issue 8, Pergamin-Elsevier Science Ltd, Oxford England UK, pp. 2274-2277. View Publication
Lea-Smith, D.J., Pyke, J.S., Tull, D., McConville, M.J., Coppel, R.L., Crellin, P., 2007, The reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactan, Journal of Biological Chemistry, vol 282, issue 15, American Society of Biochemistry & Molecular Biology Inc, Bethesda MD USA, pp. 11000-11008. View Publication
Pei, x., Guo, X., Coppel, R.L., Bhattacharjee, S., Haldar, K., Gratzer, W., Mohandas, N., An, X., 2007, The ring-infected erythrocyte surface antigen (RESA) of plasmodium falciparum stabilizes spectrin tetramers and suppresses further invasion, Blood, vol 110, issue 3, American Society of Hematology, Washington DC USA, pp. 1036-1042. View Publication
Cooke, B.M., Buckingham, D.W., Glenister, F.K., Fernandez, K.M., Bannister, L.H., Marti, M., Mohandas, N., Coppel, R.L., 2006, A Maurer's cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells, Journal of Cell Biology, vol 172, issue 6, Rockefeller University Press, USA, pp. 899-908. View Publication
Sanders, P.R., Kats, L., Drew, D.R., O'Donnell, R.A., O'Neill, M.T., Maier, A.G., Coppel, R.L., Crabb, B.S., 2006, A set of glycosylphosphatidyl inositol-anchored membrane proteins of Plasmodium falciparum is refractory to genetic deletion, Infection and Immunity, vol 74, issue 7, Amer Soc Microbiology, WASHINGTON DC USA, pp. 4330-4338.
Oertelt, S., Lian, Z., Cheng, C., Chuang, Y., Padgett, K., He, X., Ridgway, W.M., Ansari, A.A., Coppel, R.L., Li, M.O., Flavell, R.A., Kronenberg, M., Mackay, I.R., Gershwin, M., 2006, Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice, Journal of Immunology, vol 177, issue 3, American Association of Immunologists, Bethesda USA, pp. 1655-1660. View Publication
Plebanski, M., Lopez, E., Proudfoot, O., Cooke, B.M., Von Itzstein, M., Coppel, R.L., 2006, Economic and practical challenges to the formulation of vaccines against endemic infectious diseases such as malaria, Methods, vol 40, issue 1, Academic Press Inc Elsevier Science, SAN DIEGO USA, pp. 77-85. View Publication
Raza, S.M., Gondal, I., Green, D.G., Coppel, R.L., 2006, Fusion of FNA-cytology and gene-expression data using Dempster-Shafer theory of evidence to predict breast cancer tumors, Bioinformation, vol 1, issue 5, Biomedical Informatics Publishing Group, India, pp. 170-175.
Bulach, D.M., Zuerner, R.L., Wilson, P., Seemann, T., McGrath, A., Cullen, P.A., Davis, J., Johnson, M., Kuczek, E., Alt, D.P., Peterson-Burch, B., Coppel, R.L., Rood, J.I., Davies, J.K., Adler, B., 2006, Genome reduction in Leptospira borgpetersenii reflects limited transmission potential, Proceedings of The National Academy of Sciences of The United States of America, vol 103, issue 39, Natl Acad Scicences, Washington DC USA, pp. 14560-14565. View Publication
Marland, Z., Beddoe, T.C., Zaker-Tabrizi, L., Lucet, I., Brammananth, R., Whisstock, J.C., Wilce, M.C.J., Coppel, R.L., Crellin, P.K., Rossjohn, J., 2006, Hijacking of a substrate-binding protein scaffold for use in mycobacterial cell wall biosynthesis, Journal of Molecular Biology, vol 359, issue 4, Academic Press Ltd Elsevier Science Ltd, London UK, pp. 983-997. View Publication
Wakabayashi, K., Lian, Z., Moritoki, Y., Lan, R.Y., Tsuneyama, K., Chuang, Y., Yang, G., Ridgway, W.M., Ueno, Y., Ansari, A.A., Coppel, R.L., Mackay, I.R., Gershwin, M.E., 2006, IL-2 receptor alpha-/- mice and the development of primary biliary cirrhosis, Hepatology, vol 44, issue 5, John Wiley & Sons Inc, Hoboken USA, pp. 1240-1249. View Publication
Rieger, r., Leung, P.S.C., Jeddeloh, M.R., Kurth, M.J., Nantz, M.H., Lam, K.S., Barsky, D., Ansari, A.A., Coppel, R.L., Mackay, I.R., Gershwin, M., 2006, Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis, Journal of Autoimmunity, vol 27, issue 1, Academic Press Ltd Elsevier Science Ltd, London UK, pp. 7-16. View Publication
Kovacevic, S., Anderson, D., Morita, Y.S., Patterson, J., Haites, R.E., McMillan, B.N.I., Coppel, R.L., McConville, M.J., Billman-Jacobe, H., 2006, Identification of a novel protein with a role in lipoarabinomannan biosynthesis in Mycobacteria, The Journal of Biological Chemistry, vol 281, issue 14, The American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 9011-9017. View Publication
Chuang, Y., Lian, Z., Tsuneyama, K., Chiang, B., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 2006, Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis, Journal of Autoimmunity, vol 26, issue 4, Academic Press Ltd Elsevier Science Ltd, London UK, pp. 232-240.
Lan, R.Y., Cheng, C., Lian, Z., Tsuneyama, K., Yang, G., Moritoki, Y., Chuang, Y., Nakamura, T., Saito, S., Shimoda, S., Tanaka, A., Bowlus, C.L., Takano, Y., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 2006, Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis, Hepatology, vol 43, issue 4, John Wiley & Sons Inc, USA, pp. 729-737. View Publication
He, X., Ansari, A.A., Ridgway, W.M., Coppel, R.L., Gershwin, M.E., 2006, New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis, Cellular Immunology, vol 239, issue 1, Academic Press Inc Elserier Science, SAN DIEGO CA USA, pp. 1-13.
Kats, L., Black, C.G., Proellocks, N.I., Coppel, R.L., 2006, Plasmodium rhoptries: how things went pear-shaped, Trends in Parasitology, vol 22, issue 6, ELSEVIER SCI LTD, OXON ENGLAND UK, pp. 269-276. View Publication
Mao, T.K., Lian, Z., Selmi, C., Ichiki, Y., Ashwood, P., Ansari, A.A., Coppel, R.L., Shimoda, S., Ishibashi, H., Gershwin, M.E., 2005, Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis, Hepatology, vol 42, issue 4, John Wiley & Sons, Inc., Hoboken USA, pp. 802-808. View Publication
Kikuchi, K., Lian, Z., Yang, G., Ansari, A.A., Ikehara, S., Kaplan, M.M., Miyakawa, H., Coppel, R.L., Gershwin, M., 2005, Bacterial CpG induces hyper-IgM production in CD27+ memory B cells in primary biliary cirrhosis, Gastroenterology, vol 128, issue 2, W B Saunders Co-Elsevier Inc., Philadelphia USA, pp. 304-312. View Publication
Cooke, B.M., Mohandas, N., Cowman, A.F., Coppel, R.L., 2005, Cellular adhesive phenomena in apicomplexan parasites of red blood cells, Veterinary Parasitology, vol 132, Elsevier, Amsterdam The Netherlands, pp. 273-295. View Publication
Amano, K., Leung, P.S.C., Rieger, R., Quan, C., Wang, X., Marik, J., Suen, Y.F., Kurth, M.J., Nantz, M.H., Ansari, A.A., Lam, K.S., Zeniya, M., Matsuura, E., Coppel, R.L., Gershwin, M.E., 2005, Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid, Journal of Immunology, vol 174, issue 9, American Association of Immunologists, Bethesda USA, pp. 5874-5883.
Leung, P.S.C., Coppel, R.L., Gershwin, M.E., 2005, Etiology of primary biliary cirrhosis: the search for the culprit, Seminars in Liver Disease, vol 25, issue 3, Thieme Medical Publishers, New York USA, pp. 327-336.
Marland, Z., Beddoe, T.C., Zaker-Tabrizi, L., Coppel, R.L., Crellin, P., Rossjohn, J., 2005, Expression, purification, crystallization and preliminary X-ray diffraction analysis of an essential lipoprotein implicated in cell-wall biosynthesis in Mycobacteria, Acta Crystallographica, vol 61, issue 12, Blackwell Publishing, Oxford England, pp. 1081-1083.
Matsoso, L., Kana, B.D., Crellin, P., Lea-Smith, D.J., Pelosi, A., Powell, D.R., Dawes, S.S., Rubin, H., Coppel, R.L., Mizrahi, V., 2005, Function of the cytochrome bc1-aa3 branch of the respiratory network in mycobacteria and network adaptation occurring in response to its disruption, Journal of Bacteriology, vol 187, issue 18, American Society for Microbiology, USA, pp. 6300-6308. View Publication
Kimura, Y., Selmi, C., Leung, P.S.C., Mao, T.K., Schauer, J., Watnik, M.R., Kuriyama, S., Nishioka, M., Ansari, A.A., Coppel, R.L., Invernizzi, P., Podda, M., Gershwin, M., 2005, Genetic polymorphisms influencing xenobiotic metabolism and transport in patients with primary biliary cirrhosis, Hepatology, vol 41, issue 1, John Wiley & Sons Inc., Hoboken USA, pp. 55-63. View Publication
Kikuchi, K., Lian, Z., Kimura, Y., Selmi, C., Yang, G., Gordon, S.C., Invernizzi, P., Podda, M., Coppel, R.L., Ansari, A.A., Ikehara, S., Miyakawa, H., Gershwin, M.E., 2005, Genetic polymorphisms of toll-like receptor 9 influence the immune response to CpG and contribute to hyper-IgM in primary biliary cirrhosis, Journal of Autoimmunity, vol 24, issue 4, Academic Press Ltd Elsevier Science Ltd, London England, pp. 347-352. View Publication
Chuang, Y., Lian, Z., Cheng, C., Lan, R.Y., Yang, G., Moritoki, Y., Chiang, B., Ansari, A.A., Tsuneyama, K., Coppel, R.L., Gershwin, M.E., 2005, Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relatives, Journal of Autoimmunity, vol 25, issue 2, Elsevier, London UK, pp. 126-132. View Publication
Wang, L., Kedzierski, L., Schofield, L., Coppel, R.L., 2005, Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5, Vaccine, vol 23, issue 32, Elsevier, Kidlington England, pp. 4120-4127. View Publication
Black, C.G., Wu, T., Wang, L., Topolska, A.E., Coppel, R.L., 2005, MSP8 is a non-essential merozoite surface protein in Plasmodium falciparum, Molecular & Biochemical Parasitology, vol 144, issue 1, Elsevier, The Netherlands, pp. 27-35. View Publication
Coppel, R.L., Black, C.G., 2005, Parasite genomes, International Journal for Parasitology, vol 35, issue 5, Elsevier, UK, pp. 465-479. View Publication
Padgett, K.A., Selmi, C., Kenny, T.P., Leung, P.S.C., Balkwill, D.L., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 2005, Phylogenetic and immunological definition of four lipoylated proteins from Novosphingobium aromaticivorans, implications for primary biliary cirrhosis, Journal of Autoimmunity, vol 24, issue 3, Academic Press Ltd Elsevier Science Ltd, London England, pp. 209-219. View Publication
Pouniotis, D., Proudfoot, O., Bogdanoska, V., Scalzo, K., Kovacevic, S., Coppel, R.L., Plebanski, M., 2005, Selectively impaired CD8+ but not CD4+ T cell cycle arrest during priming as a consequence of dendritic cell interaction with plasmodium-infected red cells, Journal of Immunology, vol 175, issue 6, American Association of Immunologists, USA, pp. 3525-3533.
Pei, X., An, X., Guo, X., Tarnawski, M., Coppel, R.L., Mohandas, N., 2005, Structural and functional studies of interaction between Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and erythrocyte spectrin, The Journal of Bological Chemistry, vol 280, issue 35, The American Society for Biochemistry and Molecular Biology, Inc., USA, pp. 31166-31171. View Publication
Tsuji, K., Watanabe, Y., Kouno, H., Aisaka, Y., Masanaga, T., Ishihara, H., Kamiyasu, M., Nakanishi, T., Chayama, K., Asahara, T., Coppel, R.L., Gershwin, M.E., 2004, A case of latent primary biliary cirrhosis, Hepatology Research, vol 28, issue 3, Elsevier Science Ireland Ltd, Clare Ireland, pp. 166-169.
Topolska, A.E., Richie, T.L., Nhan, D.H., Coppel, R.L., 2004, Associations between responses to the rhoptry-associated membrane antigen of Plasmodium falciparum and immunity to malaria infection, Infection and Immunity, vol 72, issue 6, American Society for Microbiology, Washington USA, pp. 3325-3330. View Publication
Cooke, B.M., Coppel, R.L., 2004, Blue skies or stormy weather: what lies ahead for malaria research?, TRENDS in Parasitology, vol 20, issue 12, Elsevier, Kidlington England, pp. 611-614. View Publication
Matsumura, S., Van de Water, J., Leung, P.S., Odin, J.A., Yamamoto, K., Gores, G.J., Mostov, K.E., Ansari, A.A., Coppel, R.L., Shiratori, Y., Gershwin, M.E., 2004, Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis, Hepatology, vol 39, issue 5, John Wiley & Sons Inc., Hoboken USA, pp. 1415-1422. View Publication
Topolska, A.E., Lidgett, A.J., Truman, D., Fujioka, H., Coppel, R.L., 2004, Characterization of a membrane-associated rhoptry protein of Plasmodium falciparum, The Journal of Biological Chemistry, vol 279, issue 6, American Society for Biochemistry and Molecular Biology, Bethesda USA, pp. 4648-4656. View Publication
Topolska, A.E., Lidgett, A.J., Truman, D., Fujioka, H., Coppel, R.L., 2004, Characterization of a membrane-associated rhoptry protein of Plasmodium falciparum, The Journal of Biological Chemistry, vol 279, issue 6, American Society for Biochemistry and Molecular Biology, Inc., Bethesda USA, pp. 4648-4656. View Publication
Selmi, C., Invernizzi, P., Keefe, E.B., Coppel, R.L., Podda, M., Rossaro, L., Ansari, A.A., Gershwin, M.E., 2004, Epidemiology and pathogenesis of primary biliary cirrhosis, Journal of Clinical Gastroenterology, vol 38, issue 3, Lippincott, Williams & Wilkins, Philadelphia USA, pp. 264-271.
Topolska, A.E., Black, C.G., Coppel, R.L., 2004, Identification and characterisation of RAMA homologues in rodent, simian and human malaria species, Molecular & Biochemical Parasitology, vol 138, issue 2, Elsevier, Amsterdam The Netherlands, pp. 237-241. View Publication
Selmi, C., Ross, S.R., Ansari, A.A., Invernizzi, P., Podda, M., Coppel, R.L., Gershwin, M.E., 2004, Lack of immunological or molecular evidence for a role of mouse mammary tumor retrovirus in primary biliary cirrhosis, Gastroenterology, vol 127, issue 2, WB Saunders Co., Philadelphia USA, pp. 493-501. View Publication
Cooke, B.M., Mohandas, N., Coppel, R.L., 2004, Malaria and the red blood cell membrane, Seminars in Hematology, vol 41, issue 2, W B Saunders Co, Philadelphia USA, pp. 173-188.
Goschnick, M.W., Black, C.G., Kedzierski, L., Holder, A.A., Coppel, R.L., 2004, Merozoite surface protein 4/5 provides Protection against lethal challenge with a heterologous malaria parasite strain, Infection and Immunity, vol 72, issue 10, American Society for Microbiology, Washington USA, pp. 5840-5849. View Publication
Black, C.G., Wang, L., Topolska, A.E., Finkelstein, D.I., Horne, M.K., Thomas, A., Mohandas, N., Coppel, R.L., 2004, Merozoite surface proteins 4 and 5 of Plasmodium knowlesi have differing cellular localisation and association with lipid rafts, Molecular & Biochemical Parasitology, vol 138, issue 1, Elsevier, Amsterdam The Netherlands, pp. 153-158. View Publication
Ichiki, Y., Leung, P.S.C., Ishibashi, H., Coppel, R.L., Ansari, A.A., Gershwin, M.E., 2004, Mitochondria and autoimmunty in primary biliary cirrhosis, Mitochondrion, vol 4, issue 5-6, Elesevier Science Ltd, Kidlington UK, pp. 743-753. View Publication
Wang, L., Goschnick, M.W., Coppel, R.L., 2004, Oral immunization with a combination of Plasmodium yoelii merozoite surface proteins 1 and 4/5 enhances protection against lethal malaria challenge, Infection and Immunity, vol 72, issue 10, American Society for Microbiology, Washington USA, pp. 6172-6175. View Publication
Wang, L., Webster, D., Wesselingh, S., Coppel, R.L., 2004, Orally delivered malaria vaccines: not too hard to swallow, Expert Opinion on Biological Therapy, vol 4, issue 10, Ashley Publications Ltd, London England, pp. 1585-1594.
Haselhorst, T., Wilson, J.C., Thomson, R.J., McAtamney, S., Menting, J.G.T., Coppel, R.L., 2004, Saturation transfer difference (STD) 1H-NMR experiments and in silico docking experiments to probe the binding of N-acetylneuraminic acid and derivatives to Vibrio cholerae sialidase, Proteins: Structure, Function, and Bioinformatics, vol 56, issue 2, Wiley-Liss, New York USA, pp. 346-353. View Publication
Mao, T.K., Davis, P.A., Odin, J.A., Coppel, R.L., Gershwin, M.E., 2004, Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis, Hepatology, vol 40, issue 6, John Wiley & Sons Inc, Hoboken USA, pp. 1241-1248. View Publication
Coppel, R.L., Roos, D.S., Bozdech, Z., 2004, The genomics of malaria infection, TRENDS in Parasitology, vol 20, issue 12, Elsevier, Kidlington England, pp. 553-557. View Publication
Amano, K., Leung, P.S.C., Xu, Q., Marik, J., Quan, C., Kurth, M.J., Nantz, M.H., Ansari, A.A., Lam, K.S., Zeniya, M., Coppel, R.L., Gershwin, M.E., 2004, Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible, The Journal of Immunology, vol 172, issue 10, The American Association of Immunologists, Inc., Bethesda USA, pp. 6444-6452.
Black, C.G., Wang, L., Wu, T., Coppel, R.L., 2003, Apical location of a novel EGF-like domain-containing protein of Plasmodium falciparum, Molecular & Biochemical Parasitology, vol 127, issue 1, Elsevier Science BV, Amsterdam The Netherlands, pp. 59-68. View Publication
Bruggraber, S.F.A., Leung, P.S.C., Amano, K., Quan, C., Kurth, M.J., Nantz, M.H., Benson, G.D., Van de Water, J., Luketic, V.A.C., Roche, T.E., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 2003, Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis, Gastroenterology, vol 125, issue 6, WB Saunders Co., Philadelphia USA, pp. 1705-1713. View Publication
Wang, L., Mohandas, N., Thomas, A., Coppel, R.L., 2003, Detection of detergent-resistant membranes in asexual blood-stage parasites of Plasmodium falciparum, Molecular & Biochemical Parasitology, vol 130, issue 2, Elsevier BV, Amsterdam The Netherlands, pp. 149-153. View Publication
Leung, P.S.C., Quan, C., Park, O., Van de Water, J., Kurth, M.J., Nantz, M.H., Ansari, A.A., Coppel, R.L., Lam, K.S., Gershwin, M.E., 2003, Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies, The Journal of Immunology, vol 170, issue 10, American Association of Immunologists, Bethesda USA, pp. 5326-5332.
Waller, K.L., Nunomura, W., An, X., Cooke, B.M., Mohandas, N., Coppel, R.L., 2003, Mature parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum binds to the 30-kDa domain of protein 4.1 in malaria-infected red blood cells, Blood, vol 102, issue 5, American Society of Hematology, Washington USA, pp. 1911-1914. View Publication
Wu, C., Eiserich, J.P., Ansari, A.A., Coppel, R.L., Balasubramanian, S., Bowlus, C.L., Gershwin, M.E., Van De Water, J., 2003, Myeloperoxidase-positive inflammatory cells participate in bile duct damage in primary biliary cirrhosis through nitric oxide-mediated reactions, Hepatology, vol 38, issue 4, WB Saunders Co., Philadelphia USA, pp. 1018-1025. View Publication
Wang, L., Crouch, L., Richie, T.L., Nhan, D.H., Coppel, R.L., 2003, Naturally acquired antibody responses to the components of the Plasmodium falciparum merozoite surface protein 1 complex, Parasite Immunology, vol 25, issue 8/9, Blackwell Publishing Ltd, Oxford England, pp. 403-412. View Publication
Wang, L., Kedzierski, L., Wesselingh, S.L., Coppel, R.L., 2003, Oral immunization with a recombinant malaria protein induces conformational antibodies and protects mice against lethal malaria, Infection and Immunity, vol 71, issue 5, American Society for Microbiology, Washington USA, pp. 2356-2364. View Publication
Selmi, C., Balkwill, D.L., Invernizzi, P., Ansari, A.A., Coppel, R.L., Podda, M., Leung, P.S., Kenny, T.P., Van De Water, J., Nantz, M.H., Kurth, M.J., Gershwin, M., 2003, Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium, Hepatology, vol 38, issue 5, WB Saunders Co., Philadelphia USA, pp. 1250-1257. View Publication
Kita, H., Ansari, A.A., He, X., Lian, Z., Van de Water, J., Coppel, R.L., Luketic, V.A.C., Kaplan, M.M., Inamori, H., Isoda, N., Sugano, K., Imawari, M., Gershwin, M.E., 2003, Proteasome is required for class I-restricted presentation by Fc receptor-mediated endocytosis in primary biliary cirrhosis, Journal of Autoimmunity, vol 21, Academic Press Ltd, Elsevier Science Ltd, London UK, pp. 175-182. View Publication
Rainczuk, A., Smooker, P.M., Kedzierski, L., Black, C.G., Coppel, R.L., Spithill, T.W., 2003, The protective efficacy of MSP4/5 against lethal Plasmodium chabaudi adami challenge is dependent on the type of DNA vaccine vector and vaccination protocol, Vaccine, vol 21, issue 21-22, Elsevier Science Ltd, Kidlington England, pp. 3030-3042. View Publication
Siekmann, J.H., Allen, L.H., Watnik, M.R., Nestel, P., Neumann, C.G., Shoenfeld, Y., Peter, J.B., Patnik, M., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 2003, Titers of antibody to common pathogens: relation to food-based interventions in rural Kenyan schoolchildren, American Journal of Clinical Nutrition, vol 77, issue 1, American Society for Clinical Nutrition, Inc., Bethesda USA, pp. 242-249.
Eisen, D., Saul, A., Fryauff, D.J., Reeder, J.C., Coppel, R.L., 2002, Alterations in Plasmodium Falciparum genotypes during sequential infections suggest the presence of strain specific immunity, American Journal of Tropical Medicine and Hygiene, vol 67, issue 1, American Society for Tropical Medicine and Hygiene, McLean USA, pp. 8-16.
Kita, H., Matsumura, S., He, X., Ansari, A.A., Lian, Z., Van De Water, J., Coppel, R.L., Kaplan, M.M., Gershwin, M., 2002, Analysis of TCR Antogonism and Molecular Mimicry of an HLA-A*0201- Restricted CTL Epitope in Primary Biliary Cirrhosis, Hepatology, vol 36, issue 4, WB Saunders Co, Philadelphia USA, pp. 918-926.
Cooke, B.M., Glenister, F.K., Mohandas, N., Coppel, R.L., 2002, Assignment of functional roles to parasite proteins in malaria-infected red blood cells by competitive flow-based adhesion assay, British Journal of Haematology, vol 117, issue 1, Blackwell Science Ltd, Oxford UK, pp. 203-211.
Fukushima, N., Nalbandian, G., Van De Water, J., White, K., Ansari, A.A., Leung, P.S., Kenny, T., Kamita, S.G., Hammock, B.D., Coppel, R.L., Stevenson, F., Ishibashi, H., Gershwin, M., 2002, Characterization of Recombinant Monoclonal IgA Anit-PDC-E2 Autoantibodies Derived from Patients with PBC, Hepatology, vol 36, issue 6, WB Saunders Co, Philadelphia USA, pp. 1383-1392.
Matsumura, S., Kita, H., He, X., Ansari, A.A., Lian, Z., Van De Water, J., Yamamoto, K., Tsuji, T., Coppel, R.L., Kaplan, M.M., Gershwin, M., 2002, Comprehensive Mapping of HLA-A*0201 - Restricted CD* T-Cell Epitopes on PDC-E2 in Primary Biliary Cirrhosis, Hepatology, vol 36, issue 5, WB Saunders Co, Philadelphia USA, pp. 1125-1134.
Glenister, F.K., Coppel, R.L., Cowman, A.F., Mohandas, N., Cooke, B.M., 2002, Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells, Blood, vol 99, issue 3, American Society of Hematology, Washington DC USA, pp. 1060-1063.
Matsumura, S., Van De Water, J., Kita, H., Coppel, R.L., Tsuji, T., Yamamoto, K., Ansari, A.A., Gershwin, M., 2002, Contribution to Antimitochondrial Antibody Production: Cleavage of Pyruvate Dehydrogenase Complex-E2 by Apoptosis-Related Proteases, Hepatology, vol 35, issue 1, WB Saunders Co, Philadelphia USA, pp. 14-22.
Kimura, Y., Leung, P.S., Kenny, T., Van De Water, J., Nishioka, M.E., Giraud, A.S., Neuberger, J.M., Benson, G.D., Kaul, R., Ansari, A.A., Coppel, R.L., Gershwin, M., 2002, Diffential Expression of Intestinal Trefoil Factor in Biliary Eptithelial Cells of Primary Biliary Cirrhosis, Hepatology, vol 36, issue 5, WB Saunders Co, Philadelphia USA, pp. 1227-1235.
Kita, H., Lian, Z., Van De Water, J., He, X., Matsumura, S., Kaplan, M.M., Luketic, V.A.C., Coppel, R.L., Ansari, A.A., Gershwin, M., 2002, Identification of HLA-A2-restricted CD8+ Cytoxic T Cell Responses in Primary Biliary Cirrhosis: T Cell Activation is Augmented by Immune Complexes Cross-Presented by Dendritic Cells, Journal of Experimental Medicine, vol 195, issue 1, The Rockerfeller University Press, New York NY USA, pp. 113-123.
Kedzierski, L., Black, C.G., Goschnick, M.W., Stowers, A.W., Coppel, R.L., 2002, Immunization with a Combination of Merzoite Surface Proteins 4/5 and 1 Enhances Protection against Lethal Challenge with Plasmodium yoelii, Infection and Immunity, vol 70, issue 12, American Society for Microbiology, Washington USA, pp. 6606-6613.
Plebanski, M., Proudfoot, O., Pouniotis, D., Coppel, R.L., Apostolopoulos, V., Flannery, G., 2002, Immunogenetics and the design of Plasmodium falciparum vaccines for use in malaria-endemic populations, The Journal of Clinical Investigation, vol 110, issue 3, American Society for Clinical Investigation, Ann Arbor USA, pp. 295-301.
Wang, L., Marshall, V.M., Coppel, R.L., 2002, Limited polymorphism of the vaccine dandidate merozoite surface protein 4 of Plasmodium faciparum, Molecular & Biochemical Parasitology, vol 120, Elsevier, Science, Amsterdam Netherlands, pp. 301-303.
Waller, K.L., Nunomura, W., Cooke, B.M., Mohandas, N., Coppel, R.L., 2002, Mapping the domains of the cytoadherence ligand Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) that bind to the knob-associated histidine-rich protein (KAHRP), Molecular & Biochemical Parasitology, vol 119, issue 1, Elsevier Science, Amsterdam Netherlands, pp. 125-129.
Kedzierski, L., Escalante, A.A., Isea, R., Black, C.G., Barnwell, J.W., Coppel, R.L., 2002, Phylogenetic analysis of the genus Plasmodium based on the gene encoding adenylosuccinate lyase, Infection, Genetics and Evolution, vol 1, Elsevier Science, Amsterdam Netherlands, pp. 297-301.
Bahl, A., Bunk, B., Coppel, R.L., Crabtree, J., Diskin, S.J., Fraunholz, M.J., Grant, G.R., Gupta, D., Huestis, R., Kissinger, J.C., Labo, P., Li, L., McWeeney, S.K., Milgram, A.J., Roos, D.S., Shug, J., Stoeckert Jnr, C.J., 2002, PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished), Nucleic Acids Research, vol 30, issue 1, Oxford University Press, Oxford UK, pp. 87-90.
Kita, H., Naidenko, O.V., Kronenberg, M., Ansari, A.A., Rogers, P., He, X., Koning, F., Mikayama, T., Van De Water, J., Coppel, R.L., Kaplan, M.M., Gershwin, M., 2002, Quantitation and Phenotypic Analysis of Natural Killer T Cells in Primary Biliary Cirrhosis Using a Human CD1d Tetramer, Gastroenterology, vol 123, WB Saunders, Philadelphia USA, pp. 1031-1043.
Kita, H., Matsumura, S., He, X., Ansari, A.A., Lian, Z., Van De Water, J., Coppel, R.L., Kaplan, M.M., Gershwin, M., 2002, Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis, The Journal of Clinical Investigation, vol 109, issue 9, American Society for Clinical Investigation, Ann Arbor USA, pp. 1231-1240.
Black, C.G., Barnwell, J.W., Huber, C.S., Galinski, M.R., Coppel, R.L., 2002, The Plasmodium vivax homologues of merozoite surface proteins 4 and 5 from Plasmodium falciparum are expressed at different locations in the merozoite, Molecular & Biochemical Parasitology, vol 120, issue 2, Elsevier Science, Amsterdam Netherlands, pp. 215-224.
Weisman, S., Wang, L., Billman-Jacobe, H., Nhan, D.H., Richie, T.L., Coppel, R.L., 2001, Antibody responses to infections with strains of plasmodium falciparum expressing diverse forms of merozoite surface protein 2, Infection and immunity, vol 69, issue 2, American Society for Microbiology, Washington DC USA, pp. 959-967.
Coppel, R.L., 2001, Bioinformatics and the malaria genome: facilitating access and exploitation of sequence information, Molecular and Biochemical Parasitology, vol 118, issue 2, Elsevier Science, Amsterdam Netherlands, pp. 139-145.
Kedzierski, L., Black, C.G., Stowers, A., Goschnick, M., Kaslow, D.C., Coppel, R.L., 2001, Comparison of the protective efficacy of yeast-derived and Escherichia coli-derived recombinant merozoite surface protein 4/5 against lethal challenge by Plasmodium yoelii, Vaccine, vol 19, Elsevier Science Ltd, Oxford England, pp. 4661-4668.
Wang, L., Menting, J.G.T., Black, C.G., Stowers, A., Kaslow, D.C., Hoffman, S.L., Coppel, R.L., 2001, Differences in epitope recognition, isotype and titer of antisera to Plasmodium falciparum merozoite surface protein 4 raised by different modes of DNA or protein immunization, Vaccine, vol 19, Elsevier Science Ltd, Oxford England, pp. 816-824.
Stern, L., Allison, L., Coppel, R.L., Dix, T.I., 2001, Discovering patterns in Plasmodium falciparum genomic DNA, Molecular and Biochemical Parasitology, vol 118, issue 2, Elsevier Science BV, Amsterdam The Netherlands, pp. 175-186. View Publication
Tanaka, A., Leung, P.S., Kenny, T., Au-Young, J., Prindiville, T., Coppel, R.L., Ansari, A.A., Gershwin, M., 2001, Genomic analysis of differentially expressed genes in liver and biliary epithelial cells of patients with primary biliary cirrhosis, Journal of Autoimmunity, vol 17, Academic Press Ltd, London England, pp. 89-98.
Migliaccio, C., Van De Water, J., Ansari, A.A., Kaplan, M.M., Coppel, R.L., Lam, K.S., Thompson, R.E., Stevenson, F., Gershwin, M., 2001, Heterogeneous response of antimitochondrial autoantibodies and bile duct apical staining monoclonal antibodies to pyruvate dehydrogenase complex E2: the molecule versus the mimic, Hepatology, vol 33, issue 4, W B Saunders Company, USA, pp. 792-801.
Sasaki, M., Van De Water, J., Kenny, T., Gallo, M.L., Leung, P.S., Nakanuma, Y., Ansari, A.A., Coppel, R.L., Neuberger, J.M., Gershwin, M., 2001, Immunoglobulin gene usage and immunohistochemical characteristics of human monoclonal antibodies to the mitochondrial autoantigens of primary biliary cirrhosis induced in the XenoMouse (*Human Study*), Hepatology, vol 34, issue 4, W B Saunders, USA, pp. 631-637.
Long, S.A., Quan, C., Van De Water, J., Nantz, M.H., Kurth, M.J., Barsky, D., Colvin, M.E., Lam, K.S., Coppel, R.L., Ansari, A.A., Gershwin, M., 2001, Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis, Journal of Immunology, vol 167, America Association of Immunologists, Bethesda USA, pp. 2956-2963.
Black, C.G., Wu, T., Wang, L., Hibbs, A.R., Coppel, R.L., 2001, Merozoite surface protein 8 of Plasmodium falciparum contains two epidermal growth factor-like domains, Molecular & Biochemical Parasitology, vol 114, Elsevier, Amsterdam The Netherlands, pp. 217-226. View Publication
Van De Water, J., Ishibashi, H., Coppel, R.L., Gershwin, M., 2001, Molecular mimicry and primary biliary cirrhosis: premises not promises, Hepatology, vol 33, issue 4, W B Saunders Co., Philadelphia USA, pp. 771-775. View Publication
Wang, L., Richie, T.L., Stowers, A., Nhan, D.H., Coppel, R.L., 2001, Naturally acquired antibody responses to plasmodium falciparum merozoite surface protein 4 in a population living in an area of endemicity in Vietnam, Infection and Immunity, vol 69, issue 7, American Society for Microbiology, Washington DC USA, pp. 4390-4397.
Nishio, A., Bass, N.M., Luketic, V.A.C., Coppel, R.L., Gershwin, M., 2001, Primary biliary cirrhosis: from induction to destruction, Seminars in Gastrointestinal Disease, vol 12, issue 2, W.B. Saunders Co., USA, pp. 89-102.
Uhlemann, A., Oguariri, M., McColl, D.J., Coppel, R.L., Kremsner, P.G., Anders, R.F., Kun, J.F.J., 2001, Properties of the plasmodium falciparum homologue of a protective vaccine candidate of plasmodium yoelii, Molecular and Biochemical Parasitology, vol 118, Elsevier Science, Amsterdam Netherlands, pp. 41-48.
Cooke, B.M., Mohandas, N., Coppel, R.L., 2001, The malaria-infected red blood cell:structural and functional changes, Advances in parasitology Vol 50, vol 50, Academic Press Inc, San Diego USA, pp. 1-86.
Wang, L., Menting, J.G.T., Stowers, A., Charoenvit, Y., Sacci Jr, J.B., Coppel, R.L., 2000, Antigens cross reactive with Plasmodium falciparum merozoite surface protein 4 are found in pre-erythrocytic and sexual stages, Molecular and Biochemical Parasitology, vol 109, Elsevier Science BV, Amsterdam Netherlands, pp. 189-194.
Kedzierski, L., Black, C.G., Coppel, R.L., 2000, Characterisation of the merozoite surface protein 4/5 gene of Plasmodium berghei and Plasmodium yoelii, Molecular and Biochemical Parasitology, vol 105, Elsevier Science BV, Amsterdam Netherlands, pp. 137-147.
Sasaki, M., Ansari, A.A., Pumford, N., Van De Water, J., Leung, P.S., Humphries, K.M., Szweda, L.I., Nakanuma, Y., Roche, T.E., Coppel, R.L., Bach, J., Gershwin, E., 2000, Comparative immunoreactivity of anti-trifuloroacetyl (TFA) antibody and anti-lipoic acid antibody in primary biliary cirrhosis: Searching for a mimic, Journal of Autoimmunity, vol 15, Academic Press Ltd, London UK, pp. 51-60.
Reynoso-Paz, S., Leung, P.S., Van De Water, J., Tanaka, A., Munoz, S., Bass, N.M., Lindor, K., Donald, P.J., Coppel, R.L., Ansari, A.A., Gershwin, E., 2000, Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis, Hepatology, vol 31 issue 1, WB Saunders Co, Philadelphia USA, pp. 24-29.
Cooke, B.M., Wahlgren, M., Coppel, R.L., 2000, Falciparum malaria: Sticking up, standing out and out-standing, Parasitology Today, vol 16 issue 10, Elsevier Science Ltd, Amsterdam Netherlands, pp. 416-420.
Kedzierski, L., Black, C.G., Coppel, R.L., 2000, Immunization with recombinant Plasmodium yoelii merozoite surface protein 4/5 protects mice against lethal challenge, Infection and Immunity, vol 68 issue 10, American Society for Microbiolgy, Washington USA, pp. 6034-6037.
Magowan, C., Nunomura, W., Waller, K.L., Yeung, J., Liang, J., Van Dort, H., Low, P.S., Coppel, R.L., Mohandas, N., 2000, Plasmodium falciparum histidine-rich protein 1 associates with the band 3 binding domain of ankyrin in the infected red cell membrane, Biochimica et Biophysica Acta, vol 1502, Elsevier Science BV, Amsterdam Netherlands, pp. 461-470.
Gershwin, M., Ansari, A.A., Mackay, I.R., Nakanuma, Y., Nishio, A., Rowley, M.J., Coppel, R.L., 2000, Primary biliary cirrhosis: an orchestrated immune response against epithelial cells, Immunological Reviews, vol 174 issue 1, Munksgaard International Publishers Ltd, Copenhagen Denmark, pp. 210-225.
Black, C.G., Coppel, R.L., 2000, Synonymous and non-synonymous mutations in a region of the Plasmodium chabaudi genome and evidence for selection acting on a malaria vaccine candidate, Molecular and Biochemical Parasitology, vol 111, Elsevier Science BV, Amsterdam Netherlands, pp. 447-451.
Waterkeyn, J.G., Wickham, M.E., Davern, K.M., Cooke, B.M., Coppel, R.L., Reeder, J.C., Culvenor, J.G., Waller, R.F., Cowman, A.F., 2000, Targeted mutagenesis of Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) disrupts cytoadherence of malaria-infected red blood cells, The EMBO Journal, vol 19 issue 12, Oxford University Press, Oxford UK, pp. 2813-2823.
Nishio, A., Coppel, R.L., Ishibashi, H., Gershwin, E., 2000, The pyruvate dehydrogenase complex as a target autoantigen in primary biliary cirrhosis, Best Practice and Research Clinical Gastroenterology, vol 14 issue 4, Bailliere Tindall, London UK, pp. 535-547.
Kun, J.F.J., Waller, K.L., Coppel, R.L., 1999, "Plasmodium falciparum:" Structural and functional domains of the mature-parasite-infected erythrocyte surface antigen, Experimental Parasitology, vol 91, Academic Press Inc, San Diego USA, pp. 258-267.
Eisen, D., Marshall, V.M., Billman-Jacobe, H., Coppel, R.L., 1999, A "Plasmodium falciparum" apical membrane antigen-1 (AMA-1) gene apparently generated by intragenic recombination, Molecular and Biochemical Parasitology, vol 100, Elsevier Science BV, Amsterdam Netherlands, pp. 243-246.
Tanaka, A., Prindiville, T., Gish, R., Solnick, J.V., Coppel, R.L., Keeffe, E.B., Ansari, A.A., Gershwin, M., 1999, Are infectious agents involved in primary biliary cirrhosis? A PCR approach, Journal of Hepatology, vol 31, Munksgaard International Publishing Ltd, Copenhagen Denmark, pp. 664-671.
Quaranta, S., Shulman, H., Ahmed, A., Shoenfeld, Y., Peter, J., McDonald, G.B., Van De Water, J., Coppel, R.L., Ostlund, C., Worman, H.J., Rizzetto, M., Tsuneyama, K., Nakanuma, Y., Ansari, A.A., Locatelli, F., Paganin, S., Rosina, F., Manns, M.P., Gershwin, M., 1999, Autoantibodies in human chronic graft-versus-host disease after hematopoietic cell transplantation, Clinical Immunology, vol 91 issue 1, Acadmic Press Inc, San Diego USA, pp. 106-116.
Dubel, L., Tanaka, A., Leung, P.S., Van De Water, J., Coppel, R.L., Roche, T.E., Johanet, C., Motokawa, Y., Ansari, A.A., Gershwin, M., 1999, Autoepitope mapping and reactivity of autoantibodies to the dihydrolipoamide dehydrogenase-binding protein (E3BP) and the glycine cleavage proteins in primary biliary cirrhosis, Hepatology, vol 29 issue 4, W B Saunders Co, Philadelphia USA, pp. 1013-1018.
Billman-Jacobe, H., Haites, R.E., Coppel, R.L., 1999, Characterization of a "Mycobacterium smegmatis" mutant lacking penicillin binding protein 1, Antimicrobial Agents and Chemotherapy, vol 43 issue 12, American Society for Microbiology, Washington USA, pp. 3011-3013.
Tsuji, K., Watanabe, Y., Van De Water, J., Nakanishi, T., Kajiyama, G., Parikh-Patel, A., Coppel, R.L., Gershwin, M., 1999, Familial primary biliary cirrhosis in Hiroshima, Journal of Autoimmunity, vol 13, Academic Press Ltd, London UK, pp. 171-178.
Tanaka, A., Lindor, K., Gish, R., Batts, K.P., Shiratori, Y., Omata, M., Nelson, J.N., Ansari, A.A., Coppel, R.L., Newsome, M., Gershwin, M., 1999, Fetal microchimerism alone does not contribute to the induction of primary biliary cirrhosis, Hepatology, vol 30 issue 4, WB Saunders Co, Philadelphia USA, pp. 833-838.
Katayanagi, K., Van De Water, J., Kenny, T., Nakanuma, Y., Ansari, A.A., Coppel, R.L., Gershwin, M., 1999, Generation of monoclonal antibodies to murine bile duct epithelial cells: identification of annexin V as a new marker of small intrahepatic bile ducts, Hepatology, vol 29 issue 4, W B Saunders Co, Philadelphia USA, pp. 1019-1025.
Billman-Jacobe, H., McConville, M.J., Haites, R.E., Kovacevic, S., Coppel, R.L., 1999, Identification of a peptide synthetase involved in the biosynthesis of glycopeptidolipids of "Mycobacterium smegmatis", Molecular Microbiology, vol 33 issue 6, Blackwell Science Ltd, Oxford UK, pp. 1244-1253.
Black, C.G., Wang, L., Hibbs, A.R., Werner, E.B., Coppel, R.L., 1999, Identification of the "Plasmodium chabaudi" homologue of merozoite surface proteins 4 and 5 of "Plasmodium falciparum", Infection and Immunity, vol 67 issue 5, American Society for Microbiology, Washington USA, pp. 2075-2081.
Wu, T., Black, C.G., Wang, L., Hibbs, A.R., Coppel, R.L., 1999, Lack of sequence diversity in the gene encoding merozoite surface protein 5 of "Plasmodium falciparum", Molecular and Biochemical Parasitology, vol 103, Elsevier Science BV, Amsterdam Netherlands, pp. 243-250.
Waller, K.L., Cooke, B.M., Nunomura, W., Mohandas, N., Coppel, R.L., 1999, Mapping the binding domains involved in the interaction between the "Plasmodium falciparum" knob-associated histidine-rich protein (KAHRP) and the cytoadherence ligand "P. falciparum" erythrocyte membrane protein 1 (PfEMP1), The Journal of Biological Chemistry, vol 274 issue 34, Amer Soc for Biochemistry & Molecular Biology Inc, Bethesda USA, pp. 23808-23813.
Wang, L., Black, C.G., Marshall, V.M., Coppel, R.L., 1999, Structural and antigenic properties of merozoite surface protein 4 of "Plasmodium falciparum", Infection and Immunity, vol 67 issue 5, Americal Society for Microbiology, Washington USA, pp. 2193-2200.
Quaranta, S., Van De Water, J., Ishibashi, H., Rosina, F., Coppel, R.L., Uibo, R., Gershwin, M., 1999, The immunopathogenesis of primary biliary cirrhosis, Hepato-Gastroenterology, vol 46, HGE Update Medical Publishing Ltd, Athens Greece, pp. 3041-3047.
Tanaka, A., Quaranta, S., Mattalia, A., Coppel, R.L., Rosina, F., Manns, M.P., Gershwin, M., 1999, The tumor necrosis factor-alpha promoter correlates with progression of primary biliary cirrhosis, Journal of Hepatology, vol 30, Munksgaard International Publishing Ltd, Copenhagen Denmark, pp. 826-829.
Reynoso-Paz, S., Coppel, R.L., Ansari, A.A., Gershwin, M., 1999, Vanishing bile duct syndromes: considerations of the immunobiology of autoimmune biliary diseases, The Israel Medical Association Journal, vol 1, The Israel Medical Association, Ramat Gan Israel, pp. 37-44.
Cooke, B.M., Nicoll, C.L., Baruch, D.I., Coppel, R.L., 1998, A recombinant peptide based on PfEMP - 1 blocks and reverses adhesion of malaria - infected red blood cells to CD36 under flow, Molecular Microbiology, vol 3 no 1, Blackwell Science Ltd, Oxford UK, pp. 83-90.
Coppel, R.L., Brown, G.V., Nussenzweig, V., 1998, Adhesive proteins of the malaria parasite, Current Opinion in Microbiology, vol 1, Current Biology Publications, London UK, pp. 472-481.
Mattalia, A., Quaranta, S., Leung, P.S., Bauducci, M., Van De Water, J., Calvo, P.L., Danielle, F., Rizzetto, M., Ansari, A.A., Coppel, R.L., Rosina, F., Gershwin, E., 1998, Characterization of antimitochondrial antibodies in healthy adults, Hepatology, vol 27 no 3, W B Saunders, Philadelphia USA, pp. 656-661.
Marshall, V.M., Wu, T., Coppel, R.L., 1998, Close linkage of three merozite surface protein genes on chromosome 2 of Plasmodiumfalciparum, Molecular and Biochemical Parasitology, vol 94, Elsevier Science BV, Amsterdam Netherlands, pp. 13-25.
Shimoda, S., Van De Water, J., Ansari, A.A., Nakamura, M., Ishibashi, H., Coppel, R.L., Lake, J., Keeffe, E.B., Roche, T.E., Gershwin, E., 1998, Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis, Journal of Clinical Investigation, vol 102 no 10, American Society for Clinical Investigation, New York NY USA, pp. 1831-1840.
Masanaga, T., Watanabe, Y., Van De Water, J., Leung, P.S., Nakanishi, T., Kajiyama, G., Ruebner, B.H., Coppel, R.L., Gershwin, E., 1998, Induction and persistence of immune-mediated cholangiohepatitis in neonatally thymectomized mice, Clinical Immunology and Immunopathology, vol 89 no 2, Academic Press, New York NY USA, pp. 141-149.
Migliaccio, C., Nishio, A., Van De Water, J., Ansari, A.A., Leung, P.S., Nakanuma, Y., Coppel, R.L., Gershwin, E., 1998, Monoclonal antibodies to mitochondrial E2 components define autoepitopes in primary biliary cirrhosis, The Journal of Immunology, vol 161, Williams & Wilkins Co, Baltimore USA, pp. 5157-5163.
Malmborg, A., Shultz, D.B., Luton, F., Mostov, K.E., Richly, E., Leung, P.S., Benson, G.D., Ansari, A.A., Coppel, R.L., Gershwin, E., Van De Water, J., 1998, Penetration and co-localization in MDCK cell mitochondria of IgA derived from patients with primary biliary cirrhosis, Journal of Autoimmunity, vol 11, Academic Press, Orlando USA, pp. 573-580.
Magowan, C., Liang, J., Yeung, J., Takakuwa, Y., Coppel, R.L., Narla, M., 1998, Plasmodiumfalciparum: influence of malarial and host erythrocyte skeletal protein interactions on phosphorylation in infected erythrocytes, Experimental Parasitology, vol 89, Academic Press, Orlando USA, pp. 40-49.
Eisen, D., Billman-Jacobe, H., Marshall, V.M., Fryauff, D., Coppel, R.L., 1998, Temporal variation of the merozite surface protein - 2 gene of Plasmodiumfalciparum, Infection and Immunity, vol 66 no 1, American Society for Microbiology, Washington USA, pp. 239-246.
Yeung, J., Brown, J.T., Nair, A., Meites, E., Coppel, R.L., Narla, M., Meyer-Ilse, W., Magowan, C., 1998, X-ray microscopic visualization of specific labeling of adhesive molecule CD36 and cytoadherence by Plasmodiumfalciparum infected erytrhrocytes, Research Communications in Molecular Pathology and Pharmacology, vol 99 no 3, PJD Publications, Westbury USA, pp. 245-258.
Marshall, V.M., Silva, A., Foley, M., Cranmer, S., Wang, L., McColl, D.J., Kemp, D.J., Coppel, R.L., 1997, A second merozoite surface protein (MSP-4) of Plasmodium falciparum that contains an epidermal growth factor-like domain, Infection and Immunity, vol 65, American Society for Microbiology, Washington DC, pp. 4460-4467.
Turchany, J.M., Uibo, R.D., Kivik, T., Van De Water, J., Prindiville, T., Coppel, R.L., Gershwin, M.E., 1997, A study of antimitochondrial antibodies in a random population in Estonia, The American Journal of Gastroenterology, vol 92, Williams & Wilkins, Baltimore MD, pp. 124-126.
Cranmer, S., Magowan, C., Liang, J., Coppel, R.L., Cooke, B.M., 1997, An alternative to serum for cultivation of Plasmodium falciparum in vitro, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol 91, Royal Society of Tropical Medicine and Hygiene, London UK, pp. 363-365.
Leung, P.S., Coppel, R.L., Ansari, A.A., Munoz, S., Gershwin, M.E., 1997, Antimitochondrial antibodies in primary biliary cirrhosis, Seminars in Liver Disease, vol 17, Thieme Medical Publishers Inc, New York NY USA, pp. 61-69.
Marshall, V.M., Coppel, R.L., 1997, Characterisation of the gene encoding adenylosuccinate lyase of Plasmodium falciparum, Molecular and Biochemical Parasitology, vol 88, Elsevier Science Ireland, Shannon Co Clare Ireland, pp. 237-241.
Nishio, A., Van De Water, J., Leung, P.S., Joplin, R.E., Neuberger, J.M., Lake, J.R., Bjorkland, A., Totterman, T.H., Peters, M., Worman, H.J., Ansari, A.A., Coppel, R.L., Gershwin, M.E., 1997, Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis, Hepatology, vol 25, WB Saunders Company, Philadelphia PA, pp. 1085-1089.
Bennetts, B.J., Mohandas, N., Coppel, R.L., 1997, Defining the minimal domain of the Plasmodium falciparum protein MESA involved in the interaction with the red cell membrane skeletal protein 4.1, The Journal of Biological Chemistry, vol 272, Amer Soc for Biochemistry and Molecular Biology, Bethesda MD, pp. 15299-15306.
Harada, K., Van De Water, J., Leung, P.S., Coppel, R.L., Ansari, A.A., Nakanuma, Y., Gershwin, M.E., 1997, In situ acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th 1 subset, Hepatology, vol 25, WB Saunders Company, Philadelphia PA, pp. 791-796.
Harada, K., Van De Water, J., Leung, P.S., Coppel, R.L., Nakanuma, Y., Gershwin, M.E., 1997, In situ nucleic hybridization of pyruvate dehydrogenase complex - E2 in primary biliary cirrhosis: pyruvate dehydrogenase complex - E2 messenger RNA is expressed in hepatocytes but not in biliary epithelium, Hepatology, vol 25, WB Saunders Company, Philadelphia PA, pp. 27-32.
Magowan, C., Brown, J.T., Liang, J., Heck, J.G., Coppel, R.L., Mohandas, N., Meyer-Ilse, W., 1997, Intrancellular structures of normal and aberrant Plasmodium falciparum malaria parasites imaged by soft x-ray microscopy, Proceedings of the National Academy of Sciences of the United States of America, vol 94, The National Academy of Sciences, Washington DC, pp. 6222-6227.
Tsuneyama, K., Van De Water, J., Yamazaki, K., Suzuki, K., Sato, S., Takeda, Y., Ruebner, B.H., Yost, B.A., Nakanuma, Y., Coppel, R.L., Gershwin, M.E., 1997, Primary biliary cirrhosis an epithelitis: evidence of abnormal salivary gland immunohistochemistry, Autoimmunity, vol 26, Harwood Academic, Amsterdam Netherlands, pp. 23-31.
Crabb, B.S., Cooke, B.M., Reeder, J.C., Waller, R.F., Caruana, S.R., Davern, K.M., Wickham, M.E., Brown, G.V., Coppel, R.L., Cowman, A.F., 1997, Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress, Cell, vol 89, Cell Press, Cambridge MA, pp. 287-296.
Van De Water, J., Shimoda, S., Niho, Y., Coppel, R.L., Ansari, A.A., Gershwin, M.E., 1997, The role of T cells in primary biliary cirrhosis, Seminars in Liver Disease, vol 17, Thieme Medical Publishers Inc, New York NY USA, pp. 105-113.
Conference Proceedings
Nguyen, V., Chetty, M.R., Coppel, R.L., Wangikar, P.P., 2012, Data discretization for dynamic Bayesian network based modeling of genetic networks, Neural Information Processing 19th International Conference, ICONIP 2012 Proceedings, Part II, 12 November 2012 to 15 November 2012, Springer, Berlin Heidelberg Germany, pp. 298-306. View Publication
Nguyen, V., Chetty, M.R., Coppel, R.L., Wangikar, P.P., 2012, Local and global algorithms for learning dynamic Bayesian networks, The 12th IEEE International Conference on Data Mining (ICDM 2012), 10 December 2012 to 13 December 2012, IEEE Computer Society Press, Washington DC USA, pp. 685-694.
Nguyen, V., Chetty, M., Coppel, R., Wangikar, P., 2011, Dynamic bayesian network modeling of cyanobacterial biological processes via gene clustering, 18th International Conference on Neural Information Processing (ICONIP 2011), 13 November 2011 to 17 November 2011, Springer-Verlag, Berlin Germany, pp. 97-106. View Publication
Nguyen, V., Chetty, M., Coppel, R., Wangikar, P., 2011, Polynomial time algorithm for learning globally optimal dynamic bayesian network, 18th International Conference on Neural Information Processing (ICONIP 2011), 13 November 2011 to 17 November 2011, Springer-Verlag, Berlin Germany, pp. 719-729. View Publication
Al-deen, F.M.N., Ho, J., Selomulya, C., Ma, C., Coppel, R.L., 2010, Pei-coated superparamagnetic iron oxide for delivering malaria DNA vaccine encoding merozoit surface protein MSP1 19, Proceedings of Chemeca 2010, 26 September 2010 to 29 September 2010, Engineers Australia, Australia, pp. 1-9. View Publication
Wang, L., Ma, C.W.C., Webster, D.E., Wesselingh, S.L., Coppel, R.L., 2009, Examination of novel strategies for the production and delivery of malaria vaccines, Symposium 7: Cancer: From genes to therapy, April 24-27, The Australia Chinese Association for Biomedical Sciences Inc., Australia, p. 194.
Sehgal, M.B., Gondal, I., Dooley, L.S., Coppel, R.L., 2008, Heuristic non parametric collateral missing value imputation: A step towards robust post-genomic knowledge discovery, Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008), 15 October 2008 to 17 October 2008, Springer - Verlag, Berlin Germany, pp. 373-387.
Raza, S.M., Gondal, I., Mok, G., Green, D.G., Coppel, R.L., 2007, Fuzzy weighted bio-fusion framework for breast cancer tumor intensity using mathematical theory of evidence, PRIB 2007 Proceedings, Supplemental: Second IAPR International Workshop on Pattern Recognition in Bioinformatics, 1 October 2007 to 2 October 2007, Bioinformatics Research Centre, Singapore, pp. 1-7.
Sehgal, M.S.B., Gondal, I., Dooley, L.S., Coppel, R.L., Mok, G., 2007, Transcriptional gene regulatory network reconstruction through cross platform gene network fusion, Proceedings of the Second IAPR International Workshop on Pattern Recognition in Bioinformatics (PRIB 2007), 1 October 2007 to 2 October 2007, Springer, Germany, pp. 274-285.
Sehgal, M.S.B., Gondal, I., Dooley, L.S., Coppel, R.L., 2006, AFEGRN: adaptive fuzzy evolutionary gene regulatory network reconstruction framework, 2006 IEEE World Congress on Computational Intelligence - 2006 IEEE International Conference of Fuzzy Systems, 16 July 2006 to 21 July 2006, Omnipress Technical Support, WI USA, pp. 1737-1741.
Raza, S.M., Gondal, I., Green, D.G., Coppel, R.L., 2006, Classifier fusion using Dempster-shafer theory of evidence to predict breast cancer tumors, TENCON 2006 Hong Kong IEEE Region 10 Conference, 14 November 2006 to 17 November 2006, IEEE, Hong Kong, pp. 1-4.
Sehgal, M.S.B., Gondal, I., Dooley, L.S., Coppel, R.L., 2006, Coalesce gene regulatory network reconstruction: A cross-platform transcriptional gene network fusion framework, TENCON 2006 Hong Kong IEEE Region 10 Conference, 14 November 2006 to 17 November 2006, IEEE, Hong Kong China, pp. 1-4.
Myers, R., Dix, T.I., Coppel, R.L., Green, D.G., 2006, Polyome: a learning system for extracting bioinformatic data, Proceedings of the 2006 International Conference on Bioinformatics and Computational Biology, 26 June 2006 to 29 June 2006, CSREA Press, USA, pp. 534-540. View Publication
Raza, S.M., Gondal, I., Green, D.G., Coppel, R.L., 2005, Classifier fusion to predict breast cancer tumors based on microarray gene expression data, Proceedings of the 9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems (KES 2005), 14 September 2005 to 16 September 2005, Springer-Verlag, Berlin Germany, pp. 866-874. View Publication
Raza, S.M., Gondal, I., Green, D.G., Coppel, R.L., 2005, Comparative study of Support Vector Machine and Compound Covariant Predictor based classification for microarray gene-expression data of hereditary breast cancer, Proceedings of the 2nd International Conference on Computational Intelligence in Medicine and Healthcare, 29 June 2005 to 01 July 2005, IEE, Portugal, pp. 424-430.
Raza, S.M., Gondal, I., Green, D.G., Coppel, R.L., 2005, Comparative study of multivariate classification methods using microarray gene expression data for BRCA1/BRCA2 cancer tumors, Third International Conference on Information Technology and Applications, 04 July 2005 to 07 July 2005, IEEE Computer Society, Los Alamitos USA, pp. 475-480.
Myers, R., Dix, T.I., Coppel, R.L., Green, D.G., 2005, Database integration and querying in the bioinformatics domain, Proceedings of the ICWE 2005 Workshop on Web Information Systems Modelling, 25 July 2005 to 29 July 2005, University of Wollongong, Wollongong NSW Australia, pp. 14-20.
De Silva, H.D., Kovacevic, S., Mitri, K., Dubljevic, V., Coppel, R.L., 2005, Development of Plasmodium falciparum merozoite surface protein 4 for a subunit malaria vaccine, Tissue Antigens, Blackwell Publishing, Oxford England, p. 395.
Raza, S.M., Gondal, I., Green, D.G., Coppel, R.L., 2005, Feature selection and classification of gene expression profile in hereditary breast Cancer, Fourth International Conference on Hybrid Intelligent Systems, 05 December 2004 to 08 December 2004, IEEE Computer Society, Los Alamitos USA, pp. 315-320.
Dubel, L., Tanaka, A., Shimoda, S., Van De Water, J., Ishibashi, H., Coppel, R.L., Gershwin, M., 1999, Immunopathogenesis of primary biliary cirrhosis: contemporary issues, Diseases of the liver and the bile ducts. New aspects and clinical implications, Prague Czech Republic, 12-13 September 1998, Kluwer Academic Publishers, Dordrecht Netherland, pp. 112-125.
Cooke, B.M., Mohandas, N., Coppel, R.L., 1999, Molecular basis for the abnormal rheological properties of malaria-infected red blood cells, Biorheology, Pecs Hungary, 18-22 July 1999, IOS Press, Amsterdam Netherlands, p. 59.
Cooke, B.M., Waller, K.L., Nunomura, W., Mohandas, N., Coppel, R.L., 1999, Protein-protein interactions that influence the abnormal rheological properties of malaria-infected red blood cells, Biorheology, Pecs Hungary, 18-22 July 1999, IOS Press, Amsterdam Netherlands, p. 123.
Galperin, C., Coppel, R.L., Ansari, A.A., Gershwin, M.E., 1997, Immunopathology of vanishing bile duct syndrome, Vanishing bile duct syndrome - pathophysiology and treatment, Spoleto, Italy, 30/05-01/06/97, Kluwer Academic Publishers, Lancaster UK, pp. 159-174.
Other
Reynoso-Paz, S., Coppel, R.L., Mackay, I.R., Bass, N.M., Ansari, A.A., Gershwin, M.E., 1999, The Immunology of Bile and Biliary Epithelium, Hepatology, vol 30, issue 2, W.H. Saunders & Co, Philadelphia PA USA, pp. 351-357.
Coppel, R.L., Cooke, B.M., Magowan, C., Narla, M., 1998, Malaria and the erythrocyte, Current Opinion in Hematology. Erythrocytes, vol 5, issue 2, Lippincott-Raven Publishers, Philadelphia USA, pp. 132-138.
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