Dr Richard Burke - Researcher Profile

Biography

Richard works in the School of Biological Sciences at Monash University as a Lecturer.

Richard’s research areas of interest are:

·         Molecular genetics of Drosophila melanogaster

·         Heavy metal homeostasis

·         Invertebrate developmental biology

·         Animal models of human neurodegenerative diseases

 

 

Keywords

Molecular genetics, heavy metal homeostasis, invertebrate development biology

Qualifications

GRADUATE CERTIFICATE IN HIGHER EDUCATION

Institution: Monash University

Year awarded: 2009

DOCTOR OF PHILOSOPHY

Institution: University of Zurich, Switzerland

Year awarded: 1998

B SCIENCE

Institution: University of Melbourne, The

Year awarded: 1992

Publications

Journal Articles

Lye, J.C., Richards, C.D., Dechen, K., Paterson, D.J., De Jonge, M., Howard, D., Warr, C.G., Burke, R.E., 2012, Systematic functional characterization of putative zinc transport genes and identification of zinc toxicosis phenotypes in Drosophila melanogaster, Journal Of Experimental Biology [P], vol 215, issue 18, Company of Biologists, Cambridge England, pp. 3254-3265.

Van Hiel, M.B., Breugelmans, B., Pagel, C.N., Williams, A.K., Varan, A.K., Burke, R.E., Bowles, V.M., Batterhams, P., 2012, The ovicidal, larvacidal and adulticidal properties of 5,5'-Dimethyl-2,2'-Bipyridyl against Drosophila melanogaster, PLoS ONE [P], vol 7, issue 11, Public Library Service, San Francisco USA, pp. 1-9.

Lye, J., Hwang, E., Paterson, D., De Jonge, M., Howard, D., Burke, R., 2011, Detection of genetically altered copper levels in Drosophila tissues by synchrotron x-ray fluorescence microscopy, PLoS ONE [P], vol 6, issue 10, Public Library Science, San Francisco USA, pp. 1-8.

Southon, A., Greenough, M., Hung, Y., Norgate, M., Burke, R., Camakaris, J., 2011, The ADP-ribosylation factor 1 (Arf1) is involved in regulating copper uptake, International Journal of Biochemistry and Cell Biology [P], vol 43, issue 1, Pergamon-Elsevier Science Ltd, Oxford England, pp. 146-153.

Ponsford, J., McLaren, A., Schonberger, M., Burke, R., Rudzki, D., Olver, J., Ponsford, M., 2011, The association between Apolipoprotein E and traumatic brain injury severity and functional outcome in a rehabilitation sample, Journal of Neurotrauma [P], vol 28, issue 9, Mary Ann Liebert Inc, New Rochelle USA, pp. 1683-1692.

Southon, A., Palstra, N., Veldhuis, N., Gaeth, A., Robin, C., Burke, R., Camakaris, J., 2010, Conservation of copper-transporting P(IB)-type ATPase function, BioMetals [E], vol 23, issue 4, Springer, GZ Dordrecht Netherlands, pp. 681-694.

Sanokawa-Akakura, R., Cao, W., Allan, K., Patel, K., Heiman, G., Ganesh, A., Burke, R., Kemp, F., Bogden, J., Camakaris, J., Birge, R., Konsolaki, M., 2010, Control of alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila, PLoS ONE [P], vol 5, issue 1, Public Library of Science, San Francisco USA, pp. 1-10.

Scott, R., Hides, L., Allen, J., Burke, R., Lubman, D., 2010, Depressive and anxiety symptomatology in ecstasy users: The relative contribution of genes, trauma, life stress and drug use, Psychopharmacology [P], vol 209, issue 1, Springer, Germany, pp. 25-36.

Norgate, M., Southon, A., Greenough, M., Cater, M., Farlow, A., Batterham, P., Bush, A., Subramaniam, N., Burke, R., Camakaris, J., 2010, Syntaxin 5 is required for copper homeostasis in Drosophila and mammals, PLoS ONE [P], vol 5, issue 12, Public Library of Science, San Francisco USA, pp. 1-10.

Binks, T., Lye, J., Camakaris, J., Burke, R., 2010, Tissue-specific interplay between copper uptake and efflux in Drosophila, Journal of Biological Inorganic Chemistry [E], vol 15, issue 4, Springer, New York USA, pp. 621-628.

Burke, R.E., Commons, E.F., Camakaris, J., 2008, Expression and localisation of the essential copper transporter DmATP7 in drosophila neuronal and intestinal tissues, The International Journal of Biochemistry and Cell Biology, vol 40, issue 9, Elsevier, UK, pp. 1850-1860.

Southon, A., Farlow, A., Norgate, M.B., Burke, R.E., Camakaris, J., 2008, Malvolio is a copper transporter in Drosophila melanogaster, The Journal of Experimental Biology, vol 211, issue 5, The Company of Biologists, UK, pp. 709-716.

Norgate, M.B., Lee, E., Southon, A., Farlow, A., Batterham, P., Camakaris, J., Burke, R.E., 2006, Essential roles in development and pigmentation for the Drosophila copper transporter DmATP7, Molecular Biology of the Cell, vol 17, American Society for Cell Biology, USA, pp. 475-484.

Southon, A., Burke, R.E., Norgate, M.B., Batterham, P., Camakaris, J., 2004, Copper homoeostatis in Drosophila melanogaster S2 cells, Biochemical Journal, vol 383, Portland Press Ltd, UK, pp. 303-309.

Verhagen, A.M., Silke, J., Ekert, P.G., Pakusch, M., Kaufmann, H., Connolly, L.M., Day, C.L., Tikoo, A., Burke, R.E., Wrobel, C., Moritz, R.L., Simpson, R.J., Vaux, D.L., 2002, HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins, The Journal of Biological Chemistry, vol 277, issue 1, JBC Papers in Press, USA, pp. 445-454.

Bellotto, M., Bopp, D., Senti, K., Burke, R.E., Deak, P., Maroy, P., Dickson, B., Basler, K., Hafen, E., 2002, Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome, International Journal of Developmental Biology, vol 46, Universidad del Pais Vasco, Spain, pp. 149-157.

Postgraduate Research Supervisions

Current Supervision

Program of Study:

(MASTER'S BY RESEARCH).

Thesis Title:

A structure/function analysis of zinc efflux proteins in Drosophila melanogaster.

Supervisors:

Burke, R (Main).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Functional Characterisation of Chloride Channel Coding Genes in Drosophila Melanogaster.

Supervisors:

Burke, R (Main), Warr, C (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Investigating the function of MACPF proteins in immunity in Drosophila melanogaster.

Supervisors:

Warr, C (Main), Burke, R (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Investigating the genetic basis of zinc homeostasis in drosophila melanogaster.

Supervisors:

Burke, R (Main), Warr, C (Associate).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Investigating the role of copper in the nervous system.

Supervisors:

Burke, R (Main).

Program of Study:

(DOCTORATE BY RESEARCH).

Thesis Title:

Modelling the effect of pathogenic Menkes and Wilson disease mutations in vivo.

Supervisors:

Burke, R (Main), Warr, C (Associate).

Completed Supervision

Student:

Binks, T.

Program of Study:

Investigating Drosophila midgut copper homeostasis and novel regulation mechanisms. (PHD) 2012.

Supervisors:

Burke, R (Main).

Student:

Lye, J.

Program of Study:

Functional characterization of zinc transport genes in Drosophila melanogaster. (PHD) 2012.

Supervisors:

Burke, R (Main).