Undergraduate - UnitCHM2942 - Synthetic chemistry II

Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.

Synopsis

This unit develops further the basic principles and key aspects of synthesis, structure and reactivity of carbon based molecules and metal complexes discussed in CHM2911. It will cover aspects of aromatic and heterocyclic chemistry including electrophilic aromatic substitution; physical organic chemistry; reactive intermediates; molecular rearrangements; nucleophilic addition; properties and bonding in transition metal complexes; metal ions in biology including metalloproteins and metal based drugs including Cisplatin.

Outcomes

On completion of this unit students will have a greater appreciation of aromatic and heterocyclic chemistry and metal complexes and how these types of compounds are then applied in order to develop an understanding of: substitution, addition and elimination reactions, the reactions of carbonyl compounds and their importance in biosynthesis, drug synthesis and in the rationalisation of the properties and functions of metalloproteins. Students will also develop a well-rounded expertise in the handling and manipulation of chemicals, the use of commonly used synthetic procedures relating to the lecture material and the application of modern spectroscopic methods in the analysis of compounds. During practical classes students will become conversant with the identification and management of risks concerned with their individual experiments, experience group work, interact with modern information technologies and develop skills in report writing and oral presentation.

Assessment

Examination (2 hours): 50%
Mid-semester test (45 mins): 15%
Laboratory work: 25%
Assignment: 10% +Students must achieve a pass mark in their laboratory work to achieve an overall pass grade.

Chief examiner(s)

Dr Perran Cook

Contact hours

Three 1-hour lectures and an average of 3 hours laboratory activity per week

Prerequisites

CHM2911