6 points, SCA Band 2, 0.125 EFTSL
Undergraduate - Unit
Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.
- Second semester 2017 (Day)
This subject aims to provide students with an understanding of:
- The use of functional groups in carbon-carbon and carbon-heteroatom bond formation;
- The fundamentals of molecular orbitals in pericyclic reactions;
- The preparation and use of organometallic in organic synthesis.The synthesis of organic molecules, including naturally occurring bioactives and other drug molecules.
This will involve:
- functional group manipulation .The chemistry of organometallic reagents.
- pericyclic chemistry
- synthesis of heterocycles
- reactions of aromatic heterocycles
- synthesis of heterocyclic drugs
At the end of this unit students will be able to:
- Draw mechanisms and rationalise the outcome of a range of functional group manipulations;
- Rationalise the use of functional groups in organic synthesis;
- Understand the use of organometallic reagents in synthesis and their reaction mechanisms;
- Understand the role of molecular orbitals in pericyclic reactions;
- Apply knowledge of organometallic, pericyclic and heterocyclic reactions to the design of synthetic routes for preparing simple organic compounds.
Final exam (2 hour): 50%; Mid-semester assessments: 20%; Practical assessments: 20%; Practical exam:10%.
Contact hours for on-campus students:
- Twenty 1-hour lectures
- Ten 1-hour whole class tutorials / active learning sessions
- Nine 4-hour laboratory practical exercises, including practical exam
- Twelve hours practical report preparation
See also Unit timetable information