units

TRM4002

Faculty of Medicine, Nursing and Health Sciences

print version

This unit entry is for students who completed this unit in 2016 only. For students planning to study the unit, please refer to the unit indexes in the the current edition of the Handbook. If you have any queries contact the managing faculty for your course or area of study.

6 points, SCA Band 3, 0.125 EFTSL

Postgraduate - Unit

Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.

Faculty

Medicine, Nursing and Health Sciences

Organisational Unit

Central Clinical School

Coordinator(s)

Dr Steven Petratos

Offered

Alfred Hospital

  • First semester 2016 (On-campus block of classes)

Monash Medical Centre

  • Second semester 2016 (On-campus block of classes)

Synopsis

Translational research is a growing and exciting new discipline in medicine that deals with the development of fundamental scientific findings into tangible clinical outcomes. Translational researchers are involved in identifying a worthwhile scientific finding that can be applied to a clinical setting. Along this research and development pipeline are a series of critical check-points that provide the investigator vital tools to generate a valuable result that has merit for translation. This unit will establish a fundamental knowledge in the processes involved in developing a basic science finding through to clinical studies. The unit provides workshop-based learning in the development of discipline-specific laboratory research questions and how they are applied to broader clinical applications. The main focus of this unit is to identify how fundamental scientific questions may have multidisciplinary clinical answers. Other core learning outcomes are through understanding how scientific concepts can be marketed and communicated effectively through research pipeline procedures and the responsibilities of the researcher that may be derived from this.

Outcomes

Upon successful completion of this unit, students should be able to:

  1. Identify the pathways to commercialisation and compare the translation of research conducted primarily through universities with that of industry.
  2. Define the criteria for engaging in contract research projects with stakeholders from industry, government and academia.
  3. Discuss Good Laboratory and Good Manufacturing Practice in the context of commercialising protein and bio-product research.
  4. Apply Good Laboratory and Good Manufacturing Practice to the stages of scale-up, production and downstream processing of a bio-product.
  5. Identify and select platform technologies appropriate to a specific multi-disciplinary research project.
  6. Outline the key criteria for assessing promising drug candidates during the discovery process and discuss these using recently developed pharmaceutical examples.

Assessment

Essay 1: Intellectual property & commercialisation (1,500 words) (25%)
Essay 2: Bioprocessing/bioinformatics/biobanking/bioimaging/phenomics (1,500 words) (25%)
Media release - executive summary (500 words) (10%)
Online self-directed learning tasks (6 x 5% = 30%)
Online test (1 hour) (10%)

Workload requirements

On-campus: Approximately 60 contact hours either face-to-face workshops or online modules. The remaining 84 hours (7 hours per week over a 12 week period) is made up of private study time completing online exercises, 3 major assignments and an end of semester online test.

See also Unit timetable information

Chief examiner(s)

Prerequisites

Students need to have completed and passed a minimum of 96 credit points in an undergraduate Science Discipline programme prior to enrolling in this unit.