units

VCP4031

Faculty of Pharmacy and Pharmaceutical Sciences

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Monash University Handbook 2010 Undergraduate - Unit

6 points, SCA Band 0 (NATIONAL PRIORITY), 0.125 EFTSL

LevelUndergraduate
FacultyFaculty of Pharmacy and Pharmaceutical Sciences
OfferedParkville First semester 2010 (Day)
Coordinator(s)Dr Michelle McIntosh

Synopsis

The aim of this unit is to:

  • Complete the biopharmaceutical and pharmacokinetics and the drug delivery streams of pharmaceutics including topics relating to non-oral routes of delivery, non-linear pharmacokinetics and the pharmacokinetics of drug interactions.
  • Introduce students to the concept of therapeutic drug monitoring.
  • Develop skills to utilise the knowledge base in pharmaceutics to solve problems and deal with issues that are likely to occur in practice.

This will involve the study of:
  • Applied Pharmaceutics
  • Drug Interactions
  • Drug Delivery
  • Therapeutic Drug Monitoring
  • Non-linear Pharmacokinetics

Objectives

At the end of this unit students will be able to:
Knowledge based objectives:

  1. Describe the biopharmaceutical barriers to effective drug delivery via non-parenteral routes of drug delivery.
  2. Discuss the formulation approaches that can be employed to overcome the biopharmaceutical barriers to effective drug delivery via non-parenteral routes of drug delivery.
  3. Analyse pharmaceutical formulations and identify key excipients and describe the potential function of the excipient in the formulation.
  4. Identify mechanisms of drug interactions that impact on drug pharmacokientics and discuss the clinical consequences of these interactions.
  5. Describe the role of therapeutic drug monitoring and how it is used to optimize clinical effect.
  6. Discuss the sources and consequences of non-linear pharmacokinetics.

Skill based objectives:

  1. Use the Mechaelis-Menten equation to calculate pharmacokinetic parameters.
  2. Locate and evaluate scientific literature on pharmaceutical drug formulations.
  3. Prepare a plan and write a scientific report that reflects an understanding of the pharmaceutical and biopharmaceutical rationale behind a specific pharmaceutical formulation.

Assessment

Final exam (2 hour): 65%; mid-semester exam: 10%; Applied Pharmaceutics research project: 20%; Drug Delivery Assignment: 5%.

Chief examiner(s)

Dr Michelle McIntosh

Contact hours

28 hours of contact (24 1 hour lectures and one 2 hour workshop) and self directed learning: four on-line modules (20 hours) and an applied pharmaceutics project (24 hours)

Prerequisites

Both 3rd year Drug Delivery units

Additional information on this unit is available from the faculty at:

http://www.monash.edu.au/muso/support/students/browserset.html