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Laboratory animal allergy (LAA) - OHS information sheet number 8

November 2011

Monash University is committed to providing staff and students with a healthy and safe environment for work and study.

What is a Laboratory Animal Allergy (LAA)?

An allergy is an exaggerated reaction by the body's immune system, most frequently to proteins. In the case of a laboratory animal allergy, the proteins most commonly  associated with allergic reactions are found in animal's urine, salivia, and dander.

  1. Symptoms of LAA may include rashes and itchiness of the skin
  2. watering and redness of the eyes
  3. sneezing, dry and sore throat
  4.  cough with asthma-like symptoms

Anyone who has regular contact with laboratory animals has the potential to develop allergies to them. Although those workers who have had a personal history of asthma, seasonal allergies, and dermatitis are at increased risk, individuals with no prior history of allergies and only brief work exposures can also develop allergic reactions to laboratory animals.  Most workers who develop allergic reactions to laboratory animals will do so within one to two years of working with them.

Continued exposure, may increase the severity of symptoms.

Infrequently sensitisation may occur and this can pose a significant health risk.

Early contact with the Occupational Health Team is required

Which laboratory animals are associated with allergic reactions?

Most species of animals used in research have been identified as a source of allergic symptoms. Because mice and rats are the animals most frequently used in research studies, there are more reported allergies to rodents than any other laboratory animals.

What can be done to reduce the risk of developing an allergic reaction to laboratory animals?

The best approach for reducing the likelihood of developing an allergic reaction is to eliminate or minimise exposure to the proteins found in animal urine,saliva, and dander. A comprehensive risk assessment and implementation of appropriate control measures should be undertaken prior to working with animals.

Guiding documentation is available in Using Biologicals and Animals at Monash University and the Risk Management Program

Personal protective equipment

A gown and gloves should be worn when handling animals or changing cages.

Respiratory protection of various types, may be necessary to reduce exposure to airborne allergens. Advice on suitable and effective respiratory protection should be sought from the Occupational Health and Safety branch.

For additional information, contact the Occupational Health team on:
Telephone: 990 51014
Email: ohsehelpline@monash.edu